Patents Assigned to The Royal Institution for the Advancement of Learning (McGill University)
  • Patent number: 8898537
    Abstract: Low-Density Parity-Check (LDPC) codes offer error correction at rates approaching the link channel capacity and reliable and efficient information transfer over bandwidth or return-channel constrained links with data-corrupting noise present. LDPC codes also offer error correction performance approaching channel capacity exponentially fast in terms of the code length, linear processing complexity, and parallelism that scales with the code length. They also offer challenges relating to the decoding complexity of the binary error-correction codes themselves and error floors limiting achievable bit-error rates. A new Relaxed Half-Stochastic (RHS) decoding algorithm is presented that reduces decoding complexity for high decoding throughput applications. The RHS algorithm uses an approach based on stochastic decoding algorithms but differs significantly from the conventional approaches of LDPC decoder implementation.
    Type: Grant
    Filed: March 17, 2011
    Date of Patent: November 25, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Warren Gross, Francois Leduc-Primeau, Saied Hemati, Shie Mannor
  • Publication number: 20140343124
    Abstract: The present invention relates to novel compositions and therapeutic methods for the treatment of cancer, in particular malignant glioma. The compositions include antisense oligonucleotides or RNAs or vectors encoding them which reduce expression of downregulated in renal cell carcinoma (DRR) in tumor cells, and inhibit malignant glioma cell invasion.
    Type: Application
    Filed: May 22, 2014
    Publication date: November 20, 2014
    Applicant: The Royal Institution for The Advancement of Learning/McGill University
    Inventors: Kevin PETRECCA, Masad DAMHA, Glen DELEAVEY
  • Patent number: 8886578
    Abstract: Stabilizing the visual system for any sighted mobile system increases immunity of the mobile system's gaze and reduces information processing task complexity. Two human reflexes are the optokinetic reflex and vestibulo-ocular reflex (VOR). The VOR stabilizes retinal images during head movement by producing eye movements in the opposite direction. Improved analysis of the VOR in humans would improve the diagnosis/treatment of patients, provide improvements in visual prosthesis performance for patients, and also vision systems performance for mobile robotic systems. However, an important issue for prior art mathematical analysis techniques is the requirement to classify the nystagmus segments before applying any analysis techniques, wherein this classification should be preferably performed non-subjectively. Accordingly the inventors overcome these limitations by performing classification, i.e.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: November 11, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Henrietta Galiana, Atiyeh Ghoreyshi
  • Publication number: 20140329767
    Abstract: Nutraceutical or pharmaceutical compositions, functional foods, extracts, dietary supplements and food/feed additives enriched in phytochemicals having antioxidant and/or anti-inflammatory activity may be derived from the skin, pith, or cortex from stem tubers of select potato cultivars, such as Onaway, Russet Burbank, Purple Valley or Bora Valley cultivars. These cultivars and combinations thereof provide a useful antioxidant source enriched in ferulic acid, caffeic acid, chlorogenic acids, ascorbic acid, anthocyanins, and rutin, isomers or derivatives thereof having antioxidant and/or anti-inflammatory activity.
    Type: Application
    Filed: May 1, 2014
    Publication date: November 6, 2014
    Applicant: The Royal Institution For The Advancement Of Learning/McGill University
    Inventors: Stanley Kubow, Danielle Donnelly, Andre Piccolomini, Luis Agellon
  • Publication number: 20140323535
    Abstract: The present invention relates to novel pharmaceutically-useful compounds which are antagonists of the 5-oxo-ETE receptors, such as the OXE receptor. These compounds have use as therapeutic and/or prophylactic agents for diseases characterized by tissue eosinophilia, such as inflammatory conditions including respiratory diseases. The invention also relates to pharmaceutical compositions, to the use of such compounds and compositions as medicaments, and to therapeutic methods.
    Type: Application
    Filed: July 7, 2014
    Publication date: October 30, 2014
    Applicants: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, FLORIDA INSTITUTE OF TECHNOLOGY
    Inventors: William S. POWELL, Joshua ROKACH
  • Patent number: 8860939
    Abstract: Two dimensional (2D) optical spectroscopy, wherein the spectrum has an excitation and an emission axis, reveals information formerly hidden in one-dimensional (1D) optical spectroscopy. However, current two dimensional optical spectroscopy systems are complex laboratory arrangements and accordingly limited in deployment. According to embodiments of the invention a monolithic platform providing significantly reduced complexity and increased robustness is provided allowing for “black-box” modules allowing commercial deployment of 2D optical spectroscopy instruments. Additionally, the invention supports high pulse repetition rates as well as one quantum and two quantum measurements under electronic control.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: October 14, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Patanjali Kambhampati, Jonathan Saari, Pooja Tyagi
  • Patent number: 8855215
    Abstract: A method and a circuit are provided for providing phase or frequency synthesis using sigma-delta modulation bit-stream techniques in which data is encoded utilizing sigma-delta modulation and then digital-to-time conversion (DTC) or digital-to-frequency conversion (DFC). In some embodiments this encoded data stream is further subjected to phase or frequency domain filtering, which in some embodiments is carried out by a higher-order phase-locked loop (PLL).
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: October 7, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Gordon Roberts, Sadok Aouini
  • Publication number: 20140265720
    Abstract: Monolithically integrated capacitive micromachined transducers (CMTs) offer combined process steps, shared layers, simplified packaging, and reduced die size by overlapping the CMTs with the integrated circuit (IC) electronics. Moreover, a CMT array directly above the electronics also allows for varying the excitation signal phase to each CMT element thereby enabling beam-forming techniques. Above-IC integration is particularly attractive by not requiring any alteration of the semiconductor fabrication process and allowing subsequent implementation independent of IC fabrication. Naturally, this scheme requires that the CMT technology limit itself to IC compatible materials and chemicals, as well as process step temperatures within a specific thermal budget.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: The Royal Institution for the Advancement of Learning / McGill University
    Inventors: Mourad El-Gamal, Qing Zhang, Paul-Vahe Cicek, Frederic Nabki
  • Patent number: 8835345
    Abstract: There is provided a catalyst comprising metal nanoparticles supported on nanocrystalline cellulose and a homogeneous catalyst system comprising this catalyst colloidally suspended in a fluid. There is also provided a method of producing this catalyst and various uses thereof.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: September 16, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Audrey Moores, Ciprian M. Cirtiu
  • Publication number: 20140256926
    Abstract: The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II) processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.
    Type: Application
    Filed: August 23, 2012
    Publication date: September 11, 2014
    Applicants: Hong Kong Polytechnic University, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Masad J. Damha, Matthew Hassler, Tak-Hang Chan, Mallikarjuna Reddy Nandyala, Robert Alexander Donga
  • Patent number: 8816082
    Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds;
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: August 26, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Youla S. Tsantrizos, Joris Wim De Schutter, Yih-Shyan Lin
  • Patent number: 8815942
    Abstract: The invention relates to compounds, methods, uses, compositions, combinations, kits and packages for the prevention and/or treatment of parasite infection (e.g., Plasmodium parasites) and/or disease (e.g., malaria) based on uses of (a) cystamine, cysteamine, and analogs, derivatives, prodrugs, precursors thereof; an agent capable of inducing their production; and/or salts thereof, and (b) artemisinin and functional derivative, analog, conjugate, metabolite, prodrug or precursor thereof, and/or salts thereof.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: August 26, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Philippe Gros, Gundula Min-Oo, Anny Fortin
  • Publication number: 20140230547
    Abstract: Micromachined gyroscopes, such as those based upon microelectromechanical systems (MEMS) have the potential to dominate the rate-sensor market mainly due to their small size, low power and low cost. As MEMS gyroscopes are resonant devices requiring active excitation it would be beneficial to improve the resonator Q-factor reducing the electrical drive power requirements for the excitation circuitry. Further, many prior art MEMS gyroscope designs have multiple resonances arising from design and manufacturing considerations which require additional frequency tuning and control circuitry together with the excitation/sense circuitry. It would therefore be beneficial to enhance the bandwidth of the resonators to remove the requirement for such circuitry. Further, to address the relatively large dimensions of MEMS gyroscopes it would be beneficial for the MEMS gyroscopes to be fabricated directly above the CMOS electronics thereby reducing the die dimensions and lowering per die cost.
    Type: Application
    Filed: October 1, 2013
    Publication date: August 21, 2014
    Applicant: The Royal Institution for the Advancement of Learning / McGill University
    Inventors: Mourad El-Gamal, Mohannad Elsayed, Paul-Vahe Cicek, Frederic Nabki
  • Patent number: 8809382
    Abstract: The present invention relates to novel pharmaceutically-useful compounds which are antagonists of the 5-oxo-ETE receptors, such as the OXE receptor. These compounds have use as therapeutic and/or prophylactic agents for diseases characterized by tissue eosinophilia, such as inflammatory conditions including respiratory diseases. The invention also relates to pharmaceutical compositions, to the use of such compounds and compositions as medicaments, and to therapeutic methods.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: August 19, 2014
    Assignees: The Royal Institution for the Advancement of Learning/McGill University, Florida Institute of Technology
    Inventors: William S. Powell, Joshua Rokach
  • Publication number: 20140219279
    Abstract: Internet routers are a key component in today's Internet. Each router forwards received packets toward their final destinations based upon a Longest Prefix Matching (LPM) algorithm select an entry from a routing table that determines the closest location to the final packet destination among several candidates. Prior art solutions to LPM lookup offer different tradeoffs and that it would be beneficial for a design methodology that provides for low power large scale IP lookup engines addressing the limitations within the prior art. According to embodiments of the invention a low-power large-scale IP lookup engine may be implemented exploiting clustered neural networks (CNNs). In addition to reduced power consumption embodiments of the invention provide reduced transistor count providing for reduced semiconductor die footprints and hence reduced die cost.
    Type: Application
    Filed: February 7, 2014
    Publication date: August 7, 2014
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY
    Inventors: Warren Gross, Naoya Onizawa
  • Publication number: 20140186263
    Abstract: A maleimide-functionalized gold nanoparticle is described herein. More specifically, a maleimide-functionalized gold nanoparticle of formula (I): is described, wherein “n” and “m” are integers independently ranging from 1 to 100.
    Type: Application
    Filed: May 31, 2012
    Publication date: July 3, 2014
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Ralf Schirrmacher, Jun Zhu, R. Bruce Lennox
  • Publication number: 20140155487
    Abstract: The present invention relates to methods for the treatment of a disease or condition associated with lipid imbalance using fenretinide. The invention also relates to diagnostic and screening methods based on the determination of lipid levels.
    Type: Application
    Filed: February 5, 2014
    Publication date: June 5, 2014
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Danuta RADZIOCH, Claudine GUILBAULT, Juan Bautista DE SANCTIS
  • Patent number: 8722332
    Abstract: The invention relates to a method for determining the responsiveness of a Dirofilaria spp. nematode to a macrocyclic lactone, by determining the genotype of the nematode at a position in a P-glycoprotein gene of the nematode corresponding to position 11, and optionally to position 618, in SEQ ID NO: 1, wherein the genotype GG at a position corresponding to position 11, or at positions corresponding to positions 11 and 618, in SEQ ID NO: 1 indicates that the nematode is likely resistant to the macrocyclic lactone. The invention also relates to methods for selecting a treatment to treat an animal infected with macrocyclic lactone resistant Dirofilaria spp nematode, and treating the animal; or for selecting a prophylactic to prevent an animal from becoming infected with a macrocyclic lactone resistant Dirofilaria spp nematode, and providing the prophylactic to the animal. The invention further relates to an isolated nucleic acid having at least 80% sequence identity to SEQ ID NO: 1.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: May 13, 2014
    Assignees: The Royal Institution for the Advancement of Learning/McGill University, Novartis AG
    Inventors: Roger Prichard, Catherine Bourguinat, Timothy Geary, Rudolf Schenker
  • Publication number: 20140120149
    Abstract: A composite comprising monetite and calcium sulphate is provided.
    Type: Application
    Filed: October 30, 2013
    Publication date: May 1, 2014
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: ANDREW FLYNN, J. DENNIS BOBYN, MICHAEL TANZER, JAKE E. BARRALET
  • Patent number: D704046
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: May 6, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Colin Rogers, Thomas Morrison