Patents Assigned to The State University
  • Red lettuces with increased anthocyanins, polyphenols, and oxygen radical absorption capacity
    Patent number: 9480235
    Abstract: Provided herein are several improved lettuce varieties, having increased anthocyanin and polyphenol content, and increased oxygen radical absorption capacity, as compared to other known varieties of lettuce. Also provided are parts of such new lettuces, such as leaves, heads, seeds, tissue cultures, and extracts generated from such varieties. The disclosure also provides methods of using the new lettuces and parts thereof, for example to reduce blood glucose levels.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: November 1, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Ilya Raskin, Diana Cheng, Natalia Pogrebnyak
  • Proteins expressed by mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines
    Patent number: 9482671
    Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: November 1, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Maria L. Gennaro
  • Metal fluoride compositions for self formed batteries
    Patent number: 9484594
    Abstract: The described invention provides compositions related to an electronically insulating amorphous or nanocrystalline mixed ionic conductor composition comprising a metal fluoride composite to which an electrical potential is applied to form 1) a negative electrode, and 2) a positive electrode, wherein the negative electrode and positive electrode are formed in situ.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: November 1, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Glenn G. Amatucci, Anna Halajko, Fadwa Badway
  • Attenuated viruses useful for vaccines
    Patent number: 9476032
    Abstract: This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: October 25, 2016
    Assignee: The Research Foundation for The State University of New York
    Inventors: Eckard Wimmer, Steve Skiena, Steffen Mueller, Bruce Futcher, Dimitris Papamichail, John Robert Coleman, Jeronimo Cello
  • Antimicrobial agents
    Patent number: 9475783
    Abstract: The invention provides compounds of formula (I): wherein R1-R7 and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: October 25, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Ajit Parhi, Yongzheng Zhang, Daniel S. Pilch, Malvika Kaul
  • Coherent imaging fiber based hair removal device
    Patent number: 9474576
    Abstract: A photoepilation device including a compact hand piece applicator and a portable electronics module for use in a non-medical setting. The hand piece, which contains no electrical signals, allows the user to focus on individual hair follicles by observing a magnified image provided on a semiconductor display. The image from the hand piece is transported to a remote CCD through a coherent imaging fiber. which also delivers the therapeutic energy pulse from a remotely located source to the localized target. Destruction of pluripotential follicular stems cells found in the hair bulb and bulge regions is possible via a single low power laser diode. Control of pulse width and spot size attains a range of fluence levels up to 85 J·cm?2.
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: October 25, 2016
    Assignee: The Research Foundation for The State University of New York
    Inventor: Harbans S. Dhadwal
  • MULTIPLEX DIAGNOSTIC ASSAYS FOR LYME DISEASE AND OTHER TICK-BORNE DISEASES
    Publication number: 20160289746
    Abstract: The present invention provides novel methods of diagnosing and determining treatment strategies for Lyme disease and other tick-borne illnesses.
    Type: Application
    Filed: September 10, 2014
    Publication date: October 6, 2016
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Nikhat Parveen, Salvatore A. Marras
  • Antimicrobial agents
    Patent number: 9458150
    Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: October 4, 2016
    Assignees: Rutgers, The State University of New Jersey, Taxis Pharmaceuticals, Inc.
    Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20160271081
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: March 11, 2016
    Publication date: September 22, 2016
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit K. Parhi, Malvika Kaul, Daniel S. Pilch
  • BACTERIAL EFFLUX PUMP INHIBITORS
    Publication number: 20160271082
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: March 10, 2016
    Publication date: September 22, 2016
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Edmond J. LaVoie, Ajit K. Parhi, Gifty A. Blankson, Malvika Kaul, Daniel S. Pilch
  • Compositions and methods for gene silencing
    Patent number: 9441221
    Abstract: Compositions and methods for modulating the expression of a protein of interest are provided.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: September 13, 2016
    Assignees: Rutgers, The State University of New Jersey, Silagene, Inc.
    Inventors: Samuel Ian Gunderson, Rafal Goraczniak
  • Selectable marker gene and methods of use thereof in transplastomic plants
    Patent number: 9434952
    Abstract: Compositions and method for the generation of transplastomic plants are provided.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: September 6, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Pal Maliga
  • Macromolecules for treating atherosclerosis
    Patent number: 9434681
    Abstract: The invention includes compounds of the formula I and formula II and salts thereof, as well as methods for using the compounds of formula I and formula II for treating atherosclerosis. The invention also includes compounds of formula III and (2l) and salts thereof, as well as methods of using the compounds of formula III and (2l) for treating atherosclerosis. The invention also includes methods of encapsulating molecules using the compounds of the invention.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: September 6, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Kathryn E. Uhrich, Dawanne E. Poree, Prabhas Moghe
  • Plant genes that confer resistance to trichothecene mycotoxins and fusarium head blight
    Patent number: 9428758
    Abstract: Compositions and methods are disclosed for modulating disease resistance in plants.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: August 30, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Nilgun Ereken Tumer, John Edward McLaughlin, Mohamed Anwar Bin-Umer
  • METHODS AND MATERIALS FOR TREATING DIABETES OR LIVER STEATOSIS
    Publication number: 20160243152
    Abstract: This document provides methods and materials for treating diabetes and/or liver steatosis. For example, methods for using compositions containing a potato polysaccharide preparation to reduce one or more symptoms of diabetes or liver steatosis are provided. In some cases, a composition containing a potato polysaccharide preparation provided herein can be used to treat fatty liver disease.
    Type: Application
    Filed: August 29, 2014
    Publication date: August 25, 2016
    Applicant: The Research Foundation for The State University of New York
    Inventors: George B. STEFANO, Richard KREAM, Kirk J. MANTIONE
  • Lung targeting dual drug delivery system
    Patent number: 9421194
    Abstract: The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and bronchus related. The standard treatments for NSCLC include surgery, chemotherapy, radiation, laser and photodynamic therapy, all with various success rates depending on the stage of the cancer. National Cancer Institute assesses, however, that results of standard treatment are generally poor with only a 15 percent 5-year survival rate for combined cancer stages. Challenges facing the current chemotherapy drugs include excessive toxicity to healthy tissues and limited ability to prevent metastases. A dual drug delivery system described herein selectively targets the lung to deliver anti-cancer drugs and inhibit the formation of metastases.
    Type: Grant
    Filed: April 5, 2011
    Date of Patent: August 23, 2016
    Assignees: Rutgers, The State University of New Jersey, The Trustees of Princeton University
    Inventors: Robert K. Prud'homme, Patrick J. Sinko, Howard A. Stone, Nathalie M. Pinkerton, Lei Shi, Jiandi Wan, Sherif Ibrahim, Dayuan Gao
  • Stereospecific carbonyl reductases
    Patent number: 9422583
    Abstract: Stereospecific carbonyl reductases SCR1, SCR2, and SCR3 are described herein as are nucleotide sequences that encode these reductases. These stereospecific carbonyl reductases have anti-Prelog selectivity and have specificities that are useful for fine biochemical synthesis.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: August 23, 2016
    Assignees: Rutgers, The State University of New Jersey, Jiangnan University
    Inventors: Gaetano T. Montelione, Rong Xiao, Yao Nie, Yan Xu
  • Cold shock protein compositions and methods and kits for the use thereof
    Patent number: 9422599
    Abstract: The present invention provides cold shock protein-containing compositions for improved DNA synthesis reactions with improved reactivity, methods for synthesizing DNA using such compositions, kits for use in such methods, and DNA compositions yielded by such methods. The present invention further provides cold shock protein-containing compositions for the identification of endoribonuclease cleavage sites, methods for identifying endoribonuclease cleavage sites using such compositions, and kits for use in such methods.
    Type: Grant
    Filed: March 2, 2009
    Date of Patent: August 23, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Masayori Inouye, Sangita Phadtare, Ikunoshin Kato, Ling Zhu, Hiroyuki Mukai, Takashi Uemori, Kazue Nishiwaki
  • Dual-sensitizer-containing luminescent compounds, conjugates, and uses thereof
    Patent number: 9415111
    Abstract: The invention relates to novel luminescent compositions of matter containing two fluorophores (sensitizers), synthetic methods for making the compositions, macromolecular conjugates of the compositions, and the use of the compositions and their conjugates in various methods of detection. The invention also provides kits containing the compositions and their conjugates for use in the methods of detection.
    Type: Grant
    Filed: August 11, 2007
    Date of Patent: August 16, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Arkady Mustaev, Salvatore A. E. Marras
  • Apricot tree named ‘NJA152’
    Patent number: PP27166
    Abstract: A new and distinct apricot variety of Prunus armeniaca named ‘NJA152’ is provided. This variety is distinguished from other apricot varieties by its unique combination of a slightly later blooming habit, good production of glossy glabrous fruit with a red blush over a yellow-orange ground color, freestone flesh which has a melting texture and is moderately juicy, and flavor that is sweet-tart and aromatic.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: September 20, 2016
    Assignee: Rutgers, The State University
    Inventors: Joseph C. Goffreda, Anna M. Voordeckers