Abstract: Disclosed is a method for wet chemical functionalization of single crystal diamond surfaces that involves gentle reaction conditions. This method enables a wide range of functional groups and molecules to be tethered to the diamond surface. The method is compatible with the formation of stable nitrogen vacancy centers with long spin coherence times within nanometers of the diamond surface.

Abstract: Organic-inorganic perovskite nanoparticle compositions are described herein. In some embodiments, a nanoparticle composition comprises a layer of organic-inorganic perovskite nanocrystals, the organic-inorganic perovskite nanocrystals comprising surfaces associated with ligands of size unable to incorporate into octahedral corner sites of the perovskite crystal structure.

Abstract: Various embodiments comprise systems, methods, architectures, mechanisms, apparatus, and improvements thereof for scaling and summing a plurality of weighted-data-representative analog signals provided by columns of in-memory computing bit cells within an N×M array of bit cells such that analog accumulation or summation of the weighted-data-representative analog signals provides a scaled result for further processing.

Abstract: According to various embodiments, a cellular architecture for enhanced privacy regarding identity and location of a computing device is disclosed. The architecture includes a privacy gateway connected to the core packet forwarding gateway, where the privacy gateway is configured to authenticate the computing device while hiding the identity of the computing device by verifying authentication tokens that represent units of access. The architecture further includes an over-the-air (OTA) gateway configured to select an international mobile subscriber identity (IMSI) from a pool of valid IMSIs and deliver the selected IMSI to a subscriber identity module (SIM) card of the computing device, where the SIM card periodically shuffles the pool of valid IMSIs.

Abstract: Using thermal radiation to supply occupant comfort has long existed in the heating domain, and to a lesser scale in the cooling domain. Cooling power of radiant cooling systems is limited by the risk of condensation on the panel itself, as well as adjacent surfaces. Similarly, convective system losses to the ambient air prevent maintaining a large temperature difference from the surface and the surroundings. The disclosed approach combats these common pitfalls of radiant cooling systems in the building domain, increasing the power and therefore applicability of radiant cooling.

Abstract: Disclosed are methods for using guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof, to reduce the virulence of a bacterial pathogen. When treating a patient, the method generally involves administering to the patient a therapeutically effective dose of guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof. An alternative method involves contacting the bacterial pathogen with guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed are a system and method for active stabilization of parasitic fringes in optical spectrometers, wherein the spectrometer obtains the transmission spectrum, and a signal processor extracts the etalon drift from the spectral signatures of parasitic fringes. The disclosed approach improves spectrometer accuracy, minimizes drift, and increases time between calibrations.

Abstract: Disclosed is an enabling process for high throughput manufacturing of large variety of chemical and biological sensors that utilize well-developed spin-based sensing of analyte binding. A method for producing a nanometer scale analyte specific sensor may be provided, that includes providing a first material (such as a diamond) having a luminescent center (such as an NV center) within predetermined distance (such as 2-5 nm) of a first surface, where the luminescent center configured to emit within an optical emission range, providing photochemically active molecules (such as molecules with a photo-uncaging protective group) where an optical absorption range of the photochemically active molecules at least partially overlaps the optical emission range, coating the first surface of the first material with the photochemically active molecules, and may include placement of the photochemically active surface molecule within a distance smaller than the Forster Resonant Excitation Transfer (i.e.

Abstract: Microbial reactors are provided for ammonium oxidation. Briefly, a reactor comprises a medium including an ammonium component and a Feammox bacterium and/or enzyme(s) thereof capable of oxidizing ammonium with electron transfer to an anode in contact with the medium. As described further herein, use of the anode as an electron acceptor can mitigate or overcome the disadvantages associated Fe(III) acceptor. In some embodiments, for example, ammonium oxidation in the reactor can proceed in the absence of Fe(III) and/or other metal compounds operable to function as an electron acceptor in the medium. Moreover, the medium may further comprise one more contaminants in addition to the ammonium component.

Abstract: Disclosed are a system and method for quantifying changes in animal posture from video recordings of multiple interacting animals. Also disclosed are a system and method for training a posture identification algorithm efficiently with minimal human effort and evaluating the posture of millions of animal images. The disclosed process employs video recordings of behaving animals to produce a full set of geometrical coordinates for each body part over time. Inter alia, the disclosed system should be useful for organizations interested in doing large small-molecule screens to find drugs that affect the behavior of animals, and for those investigating new behavioral diagnostics for human patients. The disclosed system allows one to record video of animals and then automatically calculate the position of each body part over time. The output of this calculation can be used for simple analysis of the amount of movement for specific body parts, or part of a more complex scheme for measuring behaviors.

Abstract: In one aspect, phosphine compounds comprising three adamantyl moieties (PAd3) and associated synthetic routes are described herein. Each adamantyl moiety may be the same or different. For example, each adamantyl moiety (Ad) attached to the phosphorus atom can be independently selected from the group consisting of adamantane, diamantane, triamantane and derivatives thereof. Transition metal complexes comprising PAd3 ligands are also provided for catalytic synthesis including catalytic cross-coupling reactions.

Abstract: A method is disclosed for coating and patterning hydrogels in order to modify surface properties. The method exploits the water content of the hydrogel and the hydrophobicity of the reaction solvent to create a thin oxide adhesion layer on the hydrogel surface. This oxide adhesion layer enables rapid transformation of the hydrophilic, cell non-adhesive hydrogel into either a highly hydrophobic or a cell-adhesive hydrogel by reaction with an alkylphosphonic acid or an ?,?-diphosphonoalkane, respectively. Also disclosed are coated, patterned hydrogels and constructs comprising the coated, patterned hydrogels.

Abstract: Biomineralization—the synthesis of inorganic materials using proteins—has recently gained interest as a low cost, green route for the production of metal chalcogenide semiconductor nanocrystals. Typical biomineralization approaches rely on proteins or biomolecules identified from organisms which possess a native biomineralization response. Disclosed herein is an alternative biomineralization approach for synthesizing metal chalcogenide nanocrystals which uses an artificially designed de novo protein. De novo proteins are non-natural proteins, allowing for facile modification of the protein through the tuning of amino acids within the sequence. This de novo protein was employed to produce size-controlled populations of semiconductor nanocrystals, with properties consistent with those produced using traditional routes.

Abstract: A synthetic peptide may be provided for use in dissolving tau inclusions. The peptide may include a first sequence consisting of M serine residues, where M is at least 30, and may be, e.g., 36-48. The synthetic peptide may include a second sequence fused to the C— or N-terminus of the first sequence. The second sequence may include 4-7 amino acids, the 4-7 amino acids including a kinase docking site. The kinase docking site may be configured such that the kinase phosphorylates an adjacent serine residue and starts a cascade such that all serine residues in the first sequence become phosphorylated. In some embodiments, the 4-7 amino acids may include a glutamic acid residue and/or an aspartic acid residue. In some embodiments, the glutamic acid residue and/or an aspartic acid residue is adjacent to a serine residue. Introduction of these peptides to cells allows for the dissolution of tau aggregates.

Abstract: According to various embodiments, a system for detecting security vulnerabilities in at least one of cyber-physical systems (CPSs) and Internet of Things (IoT) devices is disclosed. The system includes one or more processors configured to construct an attack directed acyclic graph (DAG) unique to each CPS or IoT device of the devices. The processors are further configured to generate an aggregate attack DAG from a classification of each device and a location of each device in network topology specified by a system administrator. The processors are also configured to calculate a vulnerability score and exploit risk score for each node in the aggregate attack DAG. The processors are further configured to optimize placement of defenses to reduce an adversary score of the aggregate attack DAG.

Abstract: Disclosed is a method of debris mitigation in laser produced plasma EUV light sources. The method describes a class of magnetic field configurations which exhausts debris away from sensitive components of the EUV device. This class contains a large range of configurations that may be suited and tuned to specific application requirements with a high degree of flexibility and can be generated by coils that are located away from the light collection cone.

Abstract: Disclosed is a class of organic salts and electrolytes, generally for use with electrochemical devices. Some of these salts enable the transport of magnesium ions without the presence of any additives, such as halide ions. Precursors are generated using simple fluorinated alcohols as well as abundant reagents. These precursors, often dissolved in ethereal solvents, may be combined with an appropriate Lewis acid to result in solutions that are able to conduct ions and allow for reversible electrodeposition.

Abstract: Devices and methods for processing detected signals at a detector using a processor are provided. The system involves (i) a data compressor that implements an algorithm for converting a set of data into a compressed set of data, (ii) a machine learning (ML) module coupled to the data compressor, the ML module transforming the compressed set of data into a vector and filtering the vector, (iii) a data encryptor coupled to the ML module that encrypts the filtered vector, and (iv) an integrity protection module coupled to the ML module, wherein the integrity protection module protects the integrity of the filtered vector.

Abstract: A fabric dielectric barrier discharge (DBD) device, a textile material comprising interconnected insulated conductive fibers can be used to generate a cold homogenous plasma by forming a discharge path from a conductive core of a first fiber, to a dielectric layer surrounding the conductive core, through an air gap towards, e.g., a second fiber or human skin. When the plasma that lights in and around the air gap comes into contact with a contaminated surface (containing, e.g., bacteria and/or viruses), it induces reactive species to form on the contaminated surface, and the reactive species are then allowed to kill the bacteria and/or viruses.

Abstract: Methods and devices for additive production of multi-materials are provided. Various devices may include a plurality of toolheads, each toolhead operably coupled to a different composition and having a kinematic coupling mechanism. The compositions may include a first composition comprising a cement paste or mortar, and a second composition comprising a thermoplastic polymer and/or an elastomeric polymer. The devices may include a moveable tool mount configured to be removably coupled to the kinematic coupling mechanism of each toolhead. A processor may be included that is configured to cause the deposition of the first composition and cause the deposition of the second composition simultaneous with the first composition and/or deposit the second composition after the first composition is deposited. Systems and techniques for toolpath creation may also be provided. In-situ structures may be provided that may include cement paste in contact with a thermoplastic polymer or an elastomeric polymer.