Abstract: Embodiments are disclosed for generating full-band audio from narrowband audio using a GAN-based audio super resolution model. A method of generating full-band audio may include receiving narrow-band input audio data, upsampling the narrow-band input audio data to generate upsampled audio data, providing the upsampled audio data to an audio super resolution model, the audio super resolution model trained to perform bandwidth expansion from narrow-band to wide-band, and returning wide-band output audio data corresponding to the narrow-band input audio data.

Abstract: Methods for co-designing transformer-accelerator pairs are provided. The methods may include using a transformer embedding to generate a computational graph and a transformer model. The methods may include running the computational graph through a surrogate model and outputting accuracy data of the surrogate model. The methods may include using an accelerator embedding and the transformer model to simulate training and inference tasks and outputting hardware performance data of the transformer model. The methods may include sending the hardware performance data (such as latency, energy leakage, dynamic energy, and chip area, which may be optimizable performance parameters) and model accuracy data to a co-design optimizer. The methods may include generating an output transformer-accelerator or a transformer-edge-device pair from the co-design optimizer. The transformer model and accelerator embedding may be the output transformer-accelerator or a transformer-edge-device pair.

Abstract: Recombinant phages that infect and kill bacterial hosts in response to user-defined inputs are provided. The components that encode the user-defined inputs can be combined, such that multiple inputs are maintained on a single recombinant phage, enabling precise control over the targeting strategy. The phages can be engineered to kill a specific bacterial species or multiple species simultaneously. Recombinant phages can also be engineered to harbor fluorescent and bioluminescent reporter genes that enable them to be used for tracking, detection, and in biosensing applications. Recombinant phages can also be used to lyse bacterial cells that produce recombinant proteins, as a rapid method to enable extraction and high-level purification of potentially valuable and/or industrially important proteins. Systems are provided that can be used to control the activity of a protein of interest, by taking advantage of an interaction between Qtip and a phage repressor protein.

Abstract: Disclosed is a method to 3D print materials with defined bacterial communities into controlled, complex 3D structures, and compositions. The technique includes first providing an ink composition that includes a pre-polymer composition and a microorganism, where the pre-polymer composition includes a polymerizable monomer, a cross-linking agent, the photoinitiator, and a solvent. The technique also includes 3D printing a pattern in a hydrogel support matrix using the ink composition where the hydrogel support matrix is in a container. The technique may also include forming a 3D printed engineered living material by curing the 3D printed pattern.

Abstract: Systems and methods for fibrous material manufacturing are provided. The methods include dispensing a first stream of a solution (that includes a crosslinkable material) from first nozzle(s) into a bath containing a liquid (that includes a first material). The first nozzle(s) are submerged in the liquid. The methods include dispensing a second stream from second nozzle(s) also submerged in the liquid. The second stream(s) are configured to elongate and thin the first stream(s). The second stream contain a liquid. The liquid includes a second material, which may be the same, or may be different, form the first material. The methods include forming a fibrous material by crosslinking the crosslinkable material in the first stream (e.g., using a light source to cross-link a photo-crosslinkable material in the stream).

Abstract: A retroreflector tracking and sensing technique is provided. Systems may include a laser source, optical component(s), and a beam steering component disposed along an optical transmit path. The optical component(s) may be disposed between the laser source and the beam steering component (such as a mirror coupled to an actuator). The systems may include a position-sensitive detector (PSD). The beam steering component, one or more of the optical component(s), and the PSD may be disposed along an optical return path. The optical component(s) in the optical return path may be disposed between the beam steering component and the position-sensitive detector. The PSD may be operably coupled to a position tracking analyzer and an optical sensing analyzer. Electrical signals generated by the PSD may be configured to be used for retroreflector tracking and/or optical sensing.

Abstract: Compositions are provided that can be used to, e.g., treat or prevent infections caused by Streptococcus suis. The compositions may include one or more threoglucins in a carrier, at a total concentration of threoglucins being at least 1 ?M. The at least one threoglucin may include one or more of threoglucins A-R. Such threoglucins may be produced by, e.g., growing a culture of Streptococcus suis in the presence of niacin, nicotinamide, and/or anabasine.

Abstract: Described herein is a method of screening for a nuclease with an altered nuclease activity comprising; a) forming a first compartmentalizing reaction comprising a carrier and a variant nuclease template nucleic acid comprising a coding region for a variant nuclease, and amplifying said coding region for said variant nuclease, to obtain variant nuclease encoding nucleic acid; b) forming a second compartmentalizing reaction comprising said variant nuclease encoding nucleic acid, and performing an in vitro transcription and translation reaction to obtain variant nuclease polypeptides; and c) forming a third compartmentalizing reaction comprising said variant nuclease polypeptides, and assaying said variant nuclease polypeptides for the altered nuclease activity of said nuclease.

Abstract: According to various embodiments, a cellular architecture for enhanced privacy regarding identity and location of a computing device is disclosed. The architecture includes a next generation core (NGC). The NGC includes an authentication server function (AUSF) configured to determine whether the computing device contains a valid subscriber identity module (SIM) card, and a user plane function (UPF) configured to allow a computing device to connect to the Internet. The architecture further includes a gateway connected to the UPF, the gateway configured to authenticate the computing device while hiding the identity of the computing device by verifying authentication tokens that represent units of access.

Abstract: A system and method for modulating stress granule assembly, utilizing a protein construct that has a cell penetrating protein fused to one or more proteins that can bind with an NTF2-like domain of a G3BP protein. By configuring the protein construct with an appropriate number of proteins that being with NTF2-like domains, stress granule assembly can be upregulated or downregulated as needed to treat patients.

Abstract: Hydrophilic molecules such as biologics, which can include peptides, proteins, and other biologically-derived materials, can be used as therapeutic agents in medical applications. They can face administration challenges because of poor membrane permeability and rapid clearance from the blood stream. Methods for the formation of a core-shell-brush nanoparticle from an A-B-C triblock copolymer are set forth. A hydrophilic core can contain the biologic and the C Block of the copolymer. The shell can be comprised of the precipitated B Block, and the A Block can form a stabilizing brush layer. The particles can be assembled by sequential precipitations under defined mixing conditions. Presented herein are methods to tune release based on process parameters during particle assembly and triblock characteristics.

Abstract: A system and method for chat-based studies utilizing a plurality of users may be provided, utilizing at least one chat room processor and a plurality of remote processors. The chat room processors may be configured to receive a chat room template, create a plurality of chat rooms based on the chat room template, assign participants to one chat rooms, provide instructions associated with the chat room when all participants are present, provide questions or prompts at times defined by the chat room template or when conditions defined by the chat room template are met, collect all messages received from each participant, and storing information that includes the message, a time stamp the message was sent and/or received, and at least one unique identification code associated with the participant sending the message.

Abstract: In one aspect, organic-inorganic nanoparticle compositions are described herein comprising engineered surfaces which, in some embodiments, reduce non-radiative recombination mechanisms, thereby providing optoelectronic devices with enhanced efficiencies. In some embodiments, a nanoparticle composition comprises a layer of organic-inorganic perovskite nanocrystals, the organic-inorganic perovskite nanocrystals comprising surfaces associated with growth passivation ligands and trap passivation ligands, wherein the growth passivation ligands are larger than the trap passivation ligands and are of size unable to incorporate into octahedral corner sites of the perovskite crystal structure.

Abstract: Methods of polymer and/or oligomer depolymerization are described herein which, in some embodiments, enable facile polymer and/or oligomer decomposition under mild, non-energy intensive conditions. Briefly, a method of depolymerization comprises providing a reaction mixture comprising a transition metal catalyst, and a polymer or oligomer having a backbone including cyclobutane units, and decomposing the polymer or oligomer to provide diene monomer or alkene monomer.

Abstract: According to various embodiments, a method for reducing heading error in a magnetometer that uses Rb-87 atoms is disclosed. The method includes varying a direction and magnitude of a magnetic field at different spin polarization regimes. According to various embodiments, a magnetometer adapted for reduced heading error is disclosed. The magnetometer includes a multipass cell containing Rb-87 vapor, a pump laser operated in a pulse mode that is synchronous with a Larmor frequency, and two orthogonal probe lasers configured to rotate to vary a direction and magnitude of a magnetic field at different spin polarization regimes.

Abstract: Processes to determine the effect of genetic sequence on gene expression levels are described. Generally, models are used to determine spatial chromatin profile from genetic sequence, which can be used in several downstream applications. The effect of the spatial chromatin profile on gene expression is also determined in some instances. Various methods further develop research tools, perform diagnostics, and treat individuals based on sequence effects on gene expression levels.

Abstract: Systems and methods for tackling a significant problem in data analytics: inaccurate dataset labeling. Such inaccuracies can compromise machine learning model performance. To counter this, label error detection algorithm is provided that efficiently identifies and removes samples with corrupted labels. The provided framework (CTRL) detects label errors in two steps based on the observation that models learn clean and noisy labels in different ways. First, one trains a neural network using the noisy training dataset and obtains the loss curve for each sample. Then, one applies clustering algorithms to the training losses to group samples into two categories: cleanly-labeled and noisily-labeled. After label error detection, one removes samples with noisy labels and retrains the model.

Abstract: Disclosed is a framework called SCouT that employs a Transformer architecture to make counterfactual predictions that can be used in healthcare and other longitudinal decision-making scenarios. The disclosed approach can use longitudinal donors under an intervention to estimate the synthetic counterfactual for other units. The Transformer-based encoder-decoder model uses a causal map, which enables spatial bidirectionality, to autoregressively generate a synthetic control of a target unit.

Abstract: A process for water, mineral, and/or organics recovery, as well as devices and systems that practice the process, are disclosed. The process may include providing a plurality of evaporator structures, each structure physically separated from the others, and contacting the first end of each evaporator structure with a liquid containing a plurality of materials (such as a solvent and one or more minerals). The process may include allowing capillary forces and siphonic action to draw at least one material of the plurality of materials (which may be, e.g., the solvent, a volatile organic material, and/or a mineral) from the first end towards the second end, and evaporating one or more of the plurality of materials by transferring at least one form of environmental energy (such as solar energy, wind energy, and/or ambient heat of air) directly to each evaporator structure, thereby providing the latent heat of vaporization.

Abstract: Provided are phosphonopyrazole-based phosphohistidine analogs that are useful as haptens for the preparation of immunogens, immunogens that include these haptens linked to carrier molecules, antibodies thereto and uses of these antibodies, haptens, immunogens and phosphohistidine analogs.