Abstract: A peptide mixture suitable for eliciting an immune response, comprising a first peptide and a second peptide. The first peptide comprises a first sequence of at least (8) amino acids, wherein said first sequence has at least 75% sequence identity to a first region of (8) amino acids of SEQ ID NO: 11. This first region includes position (201) of the SEQ ID NO: 11 such that the first sequence includes the amino acid in position (201) of the SEQ ID NO: 11. The second peptide comprises a second sequence of at least (8) amino acids, wherein said second sequence has at least 75% sequence identity to a second region of (8) amino acids of SEQ ID NO: 12. This second region includes position (201) of the SEQ ID NO: 12 such that the second sequence includes the amino acid in position (201) of the SEQ ID NO: 12.

Abstract: As one example, an apparatus includes a dielectric microsensor having a microfluidic chamber that includes a capacitive sensing structure. The microfluidic chamber is adapted to receive a volume of a blood sample, and a bioactive agent is adapted to interact with the blood sample, as a sample under test (SUT), within the microfluidic chamber. A transmitter can provide an input radio frequency (RF) signal to the dielectric microsensor, and a receiver can receive an output RF signal from the dielectric microsensor. A computing device is configured to compute dielectric permittivity values for the SUT based on the output RF signal over a time interval in which the dielectric permittivity values are representative of the bioactive agent interacting with the blood sample over the time interval. The computing device is further configured to provide a readout representative of hemostatic dysfunction for the blood sample based on the dielectric permittivity values.

Abstract: Provided are a composition for treating or preventing recurrence of keloid comprising tauroursodeoxycholic acid as an active ingredient, and a method for treating keloid or preventing recurrence of keloid using the composition.

Abstract: The present invention relates to a contact lens-type dressing manufactured by using a partially cured amniotic membrane dressing and a method of manufacturing same. The method of manufacturing a partially cured contact lens-type amniotic membrane dressing, and the partially cured contact lens-type amniotic membrane dressing of the present invention have a simple manufacturing method, can produce a contact lens-type amniotic membrane without foreign matter, have excellent biocompatibility, have excellent lens compatibility such as transparency and tensile strength compared to a fully cured contact lens-type amniotic membrane dressing, and also have excellent wound healing effects, and therefore, can be effectively used for the treatment of eye diseases such as corneal damage.

Abstract: A method is provided, which comprises providing a dried body fluid card sample, extracting body fluid from said dried body fluid card sample, and detecting gene products associated with extracellular vesicles. An application of the method is also applied for diagnosing and/or prognosing a clinical condition, where gene products associated with a population of extracellular vesicles and gene products associated with the clinical condition are detected.

Abstract: Provided is a photographing apparatus including an image capturing unit including a first light source, an object lens, and a first light detector, a surface detecting unit including a second light source, the object lens, and a second light detector, a processor configured to obtain a strong reflection signal area where a reflection signal is strong in an oblique plane image obtained from the second light detector, and obtain a relative position relationship between a region of interest and a focal plane of the object lens, and an actuator configured to adjust the region of interest to be in focus.

Abstract: The disclosure provides a human laryngeal model for simulation of endoscopic guided injection laryngoplasty surgery and for an insertion of a syringe containing a fluid. The human laryngeal model includes a laryngeal body, a seat body, and a vocal cord. The seat body is mounted to the laryngeal body. The seat body has an accommodation space. The vocal cord includes a plate and at least one bag body. The plate is stacked on the seat body, the bag body is fixed to the plate and located in the accommodation space of the seat body, and the bag body has a storage space. The vocal cord is configured for the insertion of the syringe to allow the syringe to inject the fluid into the storage space of the bag body. In addition, the disclosure also provides a human head and neck model including the human laryngeal model.

Abstract: The present disclosure relates to gutta-percha containing carbon nanotubes and a preparation method therefor. The gutta-percha is prepared by mixing a raw material, prepared from the following components of eucommia ulmoide gum, zinc oxide and carbon nanotubes, and extruding the mixed raw material. An orientation factor of the carbon nanotubes in the gutta-percha is greater than 10.8. The preparation method comprises: mixing the components according to dosages, and extruding a mixed product to prepare the gutta-percha containing carbon nanotubes.

Abstract: The present disclosure relates to an artificial intelligence-based oral CT automatic color conversion device and a method for driving same. The artificial intelligence-based oral CT automatic color conversion device according to an embodiment of the present invention comprises: a storage unit which stores a color conversion image related to the bone density of an alveolar bone, which is previously prepared by a user; and a control unit which, when an oral CT input image of a patient is received, converts color of the received oral CT input image on the basis of a predetermined parameter value, and adjusts the predetermined parameter value by using an error value resulting from the converted oral CT input image and the (pre)stored color conversion image to automatically convert the color of an oral CT input image to be input later.

Abstract: There is provided a user interaction training system. The user interaction training system comprises: a photographing device configure to photograph an original image including a first object at a plurality of photographing angles; an image warping device configured to receive an image including a second object corresponding to a user and the original image including the first object photographed by the photographing device, and to generate a converted image converting the first object into a third object different from the first object based on characteristic information of the second object by using a pre-trained image warping model; and a display device configured to display the generated converted image.

Abstract: An automatic calculation method of gray-to-white-matter ratio for head computed tomography of patients with cardiac arrest is disclosed and includes an image registration step, a K-means segmentation step, a segmentation refinement step and a GWR calculation step. Measure the gray-white-matter ratio through brain computed tomography early after cardiac arrest to automatically identify the corpus callosum, caudate nucleus, putamen, and posterior branch of the internal brain cyst. It is a 3D three-dimensional structure rather than a manually selected flat circular area to evaluate the effectiveness of predicting neurological prognosis at discharge.

Abstract: In one aspect, disclosed herein is a method of diagnosing and/or prognosing a neurodegenerative disease in a subject, the method comprising: obtaining a plasma or blood sample from a subject; and detecting a level of acetylated Tau in the plasma or blood sample, wherein a level of acetylated Tau that is at least 25% or 50% higher than a control level in a healthy subject indicates that the subject has a neurodegenerative disease such as traumatic brain injury.

Abstract: A treatment of rejection of a transplant by a recipient of the transplant is disclosed. Methods for prolonging transplant survival in a recipient of the transplant, prolonging survival of the recipient, delaying and/or suppressing delayed graft function in the recipient, and/or reducing the amount of an immunosuppressant administered for transplantation. The methods include providing the transplant with a CHP or a pharmaceutically acceptable salt thereof is disclosed. Also provided is a method for the production of a pharmaceutical composition for the treatment of a transplant allowing modulating transplant survival in a recipient of the transplant.

Abstract: The present disclosure provides an anti-tumor antigen nanobody that specifically binds to a human leukocyte antigen-G. The present disclosure also provides the nucleic acid sequence of the anti-tumor antigen nanobody, use of the anti-tumor antigen nanobody for treating cancer and immune-related disorders, and a method for detecting expression levels of HLA-G.

Abstract: The present invention relates to an artificially manipulated neovascularization-associated factor for regulating neovascularization and a use thereof. More particularly, the present invention relates to a system for artificially regulating neovascularization, which includes an artificially manipulated neovascularization-associated factor for regulating neovascularization and/or a composition for artificially manipulating the neovascularization-associated factor. In a specific aspect, a neovascularization regulatory system including a neovascularization-associated factor such as artificially manipulated VEGFA, HIF1A, ANGPT2, EPAS1, or ANGPTL4 and/or an expression product thereof is provided.

Abstract: Some embodiments of the present disclosure provide a pneumothorax detection method performed by a computing device. The method may comprise obtaining predicted pneumothorax information, predicted tube information, and a predicted spinal baseline with respect to an input image from a trained pneumothorax prediction model; determining at least one pneumothorax representative position for the predicted pneumothorax information and at least one tube representative position for the predicted tube information, in a prediction image in which the predicted pneumothorax information and the predicted tube information are displayed; dividing the prediction image into a first region and a second region by the predicted spinal baseline; and determining a region in which the at least one pneumothorax representative position and the at least one tube representative position exist among the first region and the second region.

Abstract: A bypass device can be implanted into a body tissue to provide fluid channels through the body tissue. The bypass device includes an open tubular base, and a plurality of pronged features attached to the open tubular base, the pronged features being reconfigurable from a first position to a second position. In the first position the pronged features extend longitudinally along a plane of the open tubular base, and the pronged features are reconfigurable to the second position by flexing the pronged features relative to the tubular base, such that in the second position the pronged features are configured for insertion through the body tissue. The pronged features may be configured as opposing arrow-shaped tangs that are flexed to form tent structures that are insertable through the body tissue.

Abstract: This specification discloses systems, methods, devices, and other techniques for determining the location of a seizure-generating region of the brain of a mammal.

Abstract: Present invention is related to a tumor microenvironment on chip or a biochip for cell therapy having a carrier, a first cell or tissue culture area and a second cell or tissue area imbedded within the carrier. The present invention provides a biochip successfully cooperating micro fluidic technology and cell culture achieving the goal for detecting or testing the function of cell therapy for cancer or tumor.

Abstract: A vacuum therapy device for treatment of a defect internal of a human or animal body, the device comprising: a porous medium for treatment of the defect; a catheter having a proximal end and a distal end, wherein the catheter is configured to be inserted into the body to enable deployment of the porous medium through an opening at the distal end for treatment of the defect; and a suction element within the catheter, the suction element comprising a suction tube connected to the porous medium to provide suction thereat; wherein the porous medium is movable between: (i) a proximal position in which a majority of the porous medium is inside the catheter for insertion of the catheter and the porous medium into the body, and (ii) a distal position in which a portion of the porous medium is located outside the catheter for treatment of the defect; wherein a cross-section of the shape of the porous medium includes one or more spokes extending radially outward, wherein two adjacent spokes are separated by a separatio