Patents Assigned to The University of Bath
  • Publication number: 20100173977
    Abstract: The present invention relates to a crystal. In particular the present invention relates to a crystal of the N-domain of ACE protein. The present invention also relates to methods, processes, domain specific modulators, pharmaceutical compositions and uses of the N-domain crystal and the structure co-ordinates thereof.
    Type: Application
    Filed: January 10, 2007
    Publication date: July 8, 2010
    Applicants: University of Bath, University of Cape Town
    Inventors: Ravi Acharya, Edward David Sturrock
  • Publication number: 20100160180
    Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of the ACE crystal and the structure co-ordinates thereof.
    Type: Application
    Filed: February 26, 2010
    Publication date: June 24, 2010
    Applicants: UNIVERSITY OF BATH, University of Cape Town
    Inventors: Ravi Acharya, Edward Sturrock
  • Patent number: 7704319
    Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of ACE crystal and the structure coordinates thereof.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: April 27, 2010
    Assignees: University of Bath, University of Cape Town
    Inventors: Ravi Acharya, Edward Sturrock
  • Publication number: 20100010269
    Abstract: A reactor for carrying out a heterogeneously catalyzed reaction includes at least first and second reaction zones that are arranged in series and that each include catalytic material, heat transfer zones that are located between said serially arranged reaction zones, and a pulse-generating device, which is arranged to deliver pulses to liquid in the reactor. The reactor allows three-phase reactions to be carried out efficiently and can reduce the impact of deposited reaction by-products on reaction efficiency.
    Type: Application
    Filed: October 5, 2007
    Publication date: January 14, 2010
    Applicant: The University of Bath
    Inventor: Stanislaw Tadeusz Kolaczkowski
  • Publication number: 20090304269
    Abstract: A method of creating a viewable image comprises applying a colour vector or matrix comprising colour values and a coverage value to a material represented as a projective transformation matrix including a further coverage value. The method further comprises rendering the transformed illumination vector or matrix as an image vector or matrix.
    Type: Application
    Filed: August 23, 2007
    Publication date: December 10, 2009
    Applicant: University of Bath Research and Innovation Services
    Inventor: Philip Willis
  • Publication number: 20090142822
    Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of ACE crystal and the structure coordinates thereof.
    Type: Application
    Filed: July 14, 2008
    Publication date: June 4, 2009
    Applicants: UNIVERSITY OF BATH, UNIVERSITY OF CAPE TOWN
    Inventors: RAVI ACHARYA, EDWARD DAVID STURROCK
  • Patent number: 7268275
    Abstract: TcdB2, a protein from Photorhabdus luminescens W-14, and nucleotide sequences encoding TcdB2, are useful for enhancing expression of orally active Photorhabdus luminescens insecticidal toxins in heterologous organisms.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: September 11, 2007
    Assignee: University of Bath
    Inventors: Richard H. ffrench-Constant, Nicholas R. Waterfield
  • Publication number: 20070106393
    Abstract: A method of fabricating a bone substitute material comprises the steps of providing a foam material (3) having an open cell structure, distorting the shape of the foam material (3) and holding the material in a distorted shape, coating the walls of the cells of the foam material with a ceramic slip (5), removing the foam material, and sintering the ceramic slip to form a bone substitute material that is approximately a positive image of the distorted foam material (3). In another method, a granular bone material is formed from a multiplicity of pieces of foam that are not distorted.
    Type: Application
    Filed: August 12, 2004
    Publication date: May 10, 2007
    Applicant: UNIVERSITY OF BATH
    Inventors: Anthony Miles, Irene Turner, Jonathan Gittings
  • Publication number: 20060174816
    Abstract: The present invention relates to a crystal of ACE protein. The present invention further relates to methods, processes, ACE modulators, pharmaceutical compositions and uses of the ACE crystal and the structure co-ordinates thereof.
    Type: Application
    Filed: September 12, 2003
    Publication date: August 10, 2006
    Applicant: UNIVERSITY OF BATH
    Inventors: Ravi Acharya, Edward Sturrock
  • Publication number: 20040120938
    Abstract: A formulation for use as a bactericidal agent in the human or animal digestive system includes xanthine oxidoreductase. The formulation may especially be in the form of a formula feed formulation or enteral feed formulation for administration to a human or animal. The formulation is capable of functioning as a “natural antibiotic” to prevent or reduce bacterial infection within the gut, especially the neonatal gut.
    Type: Application
    Filed: December 10, 2003
    Publication date: June 24, 2004
    Applicant: The University of Bath
    Inventors: David Russell Blake, Clifford Robert Stevens, Robert Eisenthal, Roger Harrison, Timothy Marc Miller, Rachel Edwards
  • Publication number: 20040093642
    Abstract: A method for controlling endosperm size and development in plants. The method employs nucleic acid constructs encoding proteins involved in genomic imprinting, in the production of transgenic plants. The nucleic acid constructs can be used in the production of transgenic plants to affect interspecific hybridisation.
    Type: Application
    Filed: November 6, 2003
    Publication date: May 13, 2004
    Applicant: University of Bath, a Great Britain corporation
    Inventor: Roderick John Scott
  • Patent number: 6682732
    Abstract: A composition for use in the treatment of lesions of the human or animal body comprises xanthine oxidoreductase and a pharmaceutically acceptable electron donor system. The composition can accelerate wound healing, especially in a hypoxic environment.
    Type: Grant
    Filed: May 3, 2001
    Date of Patent: January 27, 2004
    Assignee: The University of Bath
    Inventors: David Russell Blake, Clifford Robert Stevens, Robert Eisenthal, Roger Harrison, Timothy Mark Millar, Tulin Bodamyali, Janos Kanczler
  • Patent number: 6639129
    Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: October 28, 2003
    Assignees: Wisconsin Alumni Research Foundation, University of Bath
    Inventors: Richard H. ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
  • Patent number: 6556719
    Abstract: A method of image compression includes significance switching of DCT coefficients in block-based embedded DCT procedures. Bitwise digitized DCT coefficients are passed through successive significance sweeps of the whole image from the most significant down to the least significant coefficient bit planes. With each new sweep, newly significant coefficients may appear within a block, and block-masking is used to transmit the addresses of those newly significant coefficients. An off-mask may also be used. The invention further relates to a hardware or software-based image encoder.
    Type: Grant
    Filed: August 17, 1999
    Date of Patent: April 29, 2003
    Assignee: University of Bath
    Inventor: Donald Martin Monro
  • Patent number: 6078619
    Abstract: An object-oriented video system is implemented as a two layer object model in a software-only video compressor. Quadtree decomposition on an error metric between the input and transmitted images directs the coder towards a foreground layer of active image fragments. A rate buffering system limits the bandwidth by transmitting only the foreground blocks which most improve the image and are above some error threshold. A high fidelity background layer is identified and communicated to the decoder, which can be used to redraw background fragments as foreground objects move across them. Blocks can be coded by various methods, such as fractal transforms or truncated DCTs. The system can be implemented in RISC processors without the need for dedicated hardware. It is suitable for low bit rate applications with slowly varying backgrounds, such as personal video communications over packet networks, or closed circuit TV surveillance.
    Type: Grant
    Filed: March 10, 1999
    Date of Patent: June 20, 2000
    Assignee: University of Bath
    Inventors: Donald Martin Monro, Jeremy Andrew Nicholls
  • Patent number: 5796257
    Abstract: A system for detecting a fault in a power line (1) includes, in the power line (1), a first circuit (4) capable of attenuating signals within a first frequency band, which is centered on a first frequency, substantially more than it attenuates signals outside the first frequency band, and, a second circuit (5) connected to the power line (1) on one side of the first circuit (4), the second circuit (5) being capable of extracting signals within a second frequency band that includes the first frequency. The relative levels of two signals extracted by the second circuit (5), are detected and signalled, the two signals being at respective frequencies which the first circuit is capable of attenuating by different relative amounts.
    Type: Grant
    Filed: June 10, 1997
    Date of Patent: August 18, 1998
    Assignee: The University of Bath
    Inventor: Allan Thomas Johns
  • Patent number: 5516788
    Abstract: The invention concerns compounds and their enantiomers of the formula IA or IB ##STR1## and pharmaceutically acceptable salts thereof wherein each of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11 and R.sup.12 is independently selected from hydrogen or an alkyl group containing 1-6 carbon atoms and R.sup.5 is an alkoxy group containing 1-6 carbon atoms. The invention further concerns pharmaceutical compositions comprising the active compounds and methods employing the compounds for the treatment of conditions associated with free radical formation.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: May 14, 1996
    Assignees: University of Bath, University of Cincinnati, School of Medicine
    Inventors: Malcolm Sainsbury, Howard G. Shertzer
  • Patent number: 5290331
    Abstract: A localized clean air system for operating theaters and a method of supplying clean air to a localized region in such situations. A fan is connected to a delivery head, which has an outlet for directing inlet clean air to the localized region in a particular pattern. A streamlined body is positioned in the outlet so that, in use, the clean air flows around the body and is modified thereby to form, immediately downstream of the body, an inner region of low velocity air encircled by an outer region of higher velocity air. Preferably, the streamlined body is symmetrical about its axis and is aligned with the clean air flow, for instance by being centrally positioned in the air outlet. The streamlined body preferably comprises a rounded head and a tapered tail. A diffuser is disposed in the clean air flow upstream of the streamlined body to minimize turbulence in the air flow.
    Type: Grant
    Filed: November 5, 1991
    Date of Patent: March 1, 1994
    Assignee: University of Bath
    Inventors: Anthony W. Miles, Norman J. Wood, Guy A. Wilson, Stephen C. Wilcox
  • Patent number: 5185360
    Abstract: Compounds of the formula ##STR1## wherein R is hydrogen or a lower alkyl group, R.sup.1 and R.sup.2 are independently selected from hydrogen or a lower alkyl group, R.sup.3, R.sup.4 and R.sup.6 are independently selected from hydrogen, halogen or a lower alkyl group,R.sup.5 is hydrogen, hydroxy, halogen, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH.sub.2 or NR.sup.11 COR.sup.12,R.sup.7, R.sup.8, R.sup.9 and R.sup.10 are independently selected from hydrogen, hydroxy, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH.sub.2 or NR.sup.11 COR.sup.12,R.sup.11 is a hydrogen or a lower alkyl group,R.sup.12 is a lower alkyl group,with the proviso that when R is hydrogen then at least one of the substituents R.sup.1 to R.sup.10 is not hydrogen, or a salt thereof, are useful as antioxidants, within the medical and non-medical field, and that when R is hydrogen, methyl or neopentyl in formula IA, then at least one of R.sup.1 to R.sup.
    Type: Grant
    Filed: June 3, 1991
    Date of Patent: February 9, 1993
    Assignees: University of Bath, University of Cincinnati
    Inventors: Malcolm Sainsbury, Howard G. Shertzer
  • Patent number: 5017122
    Abstract: An apparatus for carrying out a process for the manufacture of a moulded product by compression of a powder or granules in a die, wherein a powdered die lubricant is used, lubricant particles are electrically charged and the charged particles are fed to the die in advance of the moulding powder is provided. The apparatus includes a first feed for feeding a powdered lubricant to the die, a second feed for feeding powder to the die after the powdered lubricant, and means for maintaining the electrical potential of the die at a predetermined value different from that of the powdered lubricant.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: May 21, 1991
    Assignee: University of Bath
    Inventor: John N. Staniforth