Patents Assigned to The University of Georgia Research Foundation, Inc.
  • Patent number: 9691998
    Abstract: Briefly described, embodiments of the present disclosure relate to structures including single-walled carbon nanotube/quantum dot networks, devices including the structures, and methods of making devices including the single-walled carbon nanotube/quantum dot networks.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: June 27, 2017
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Marcus D. Lay, Pornnipa Vichchulada, Darya Asheghali
  • Publication number: 20170173175
    Abstract: Compounds, compositions, and methods are provided for covalently linking an antibody or an antibody fragment to a cargo molecule, such as a therapeutic or a diagnostic agent, using a combination of enzymatic glycan remodeling and click chemistry. The method allows a cargo molecule to be selectively and efficiently attached post-translationally to an antibody or an antibody fragment. Also provided are antibody drug conjugates, methods of making, and uses thereof.
    Type: Application
    Filed: April 8, 2015
    Publication date: June 22, 2017
    Applicant: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventor: Geert-Jan Boons
  • Patent number: 9663768
    Abstract: The invention provides compounds, compositions, non-naturally occurring organisms, and methods useful for production of 5-hydroxytryptophan (5-HTP) in a microbial cell. A microbial system which includes at least one microbial cell, such as a bacterial cell or a yeast cell, is genetically engineered to express all or a portion of non-naturally occurring biosynthetic pathway that catalyzes the conversion of a simple carbon source, such as glucose, to 5-HTP. The invention can result in improved titers of 5-HTP and permits low-cost, large scale production. Methods of making and using the genetically engineered cells are also included in the invention.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: May 30, 2017
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Yajun Yan, Xinxiao Sun
  • Publication number: 20170145447
    Abstract: The invention provides a recombinant microorganism that has been genetically engineered to contain metabolic pathway for the production of muconic acid from a salicylic acid intermediate. The genetically engineered metabolic pathway comprises both biosynthetic and biodegradative elements.
    Type: Application
    Filed: December 6, 2016
    Publication date: May 25, 2017
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Yajun Yan, Yuheng Lin
  • Patent number: 9650360
    Abstract: The present invention relates to the field of anti-mycobacterial therapeutics, in particular the treatment of tuberculosis, especially including pulmonary multidrug-resistant tuberculosis (MDR-TB), with applications in extensively drug-resistant tuberculosis (XDR-TB) and extremely drug-resistant tuberculosis (XXDR-TB), preferably in combination therapy.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: May 16, 2017
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Vasu Nair, Maurice O. Okello, Machhindra G. Gund, Byung I. Seo, Pankajkumar R. Singh, Naveen K. Mangu
  • Patent number: 9649371
    Abstract: The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/us/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to MuVIowa/us/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuV?SH) and/or incapable of expressing the V protein (rMuV?V).
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: May 16, 2017
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventor: Biao He
  • Patent number: 9629339
    Abstract: In one embodiment, a system for rearing larvae includes a plurality of culture trays arranged in at least one stack of trays, each stack comprising multiple levels of trays, each tray comprising an open-topped basin adapted to receive larvae and larval food, a feed delivery system adapted to automatically deliver larval feed to individually selected culture trays, and a water delivery system adapted to automatically deliver water to the culture trays.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: April 25, 2017
    Assignee: The University of Georgia Research Foundation, Inc.
    Inventors: G. Larry Newton, D. Craig Sheppard
  • Patent number: 9605014
    Abstract: The present invention relates to novel glycomimetic compounds that are rationally designed to inhibit the binding of various pathogens to cell surface sialylated galactose and methods of use thereof. Specifically sialic acid glycosides and C-glycosides are disclosed that form a lactam ring structure or a cyclic ether/amine ring structure with the adjacent monosaccharide residue.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 28, 2017
    Assignees: University of Georgia Research Foundation, Inc., National University of Ireland, Galway, Glycosensors and Diagnostics, LLC.
    Inventors: Robert J. Woods, Paul V. Murphy, Loretta Yang, Hannah M. K. Smith, Jenifer Hendel
  • Patent number: 9603329
    Abstract: Herein provided is a new wheat cultivar designated ‘GA 04570-10E46’ as well as the seeds, plants and derivatives of the new wheat variety ‘GA 04570-10E46’ (such as cultivars and hybrids related thereto). Also provided are tissue cultures of the new wheat variety ‘GA 04570-10E46’ and the plants regenerated therefrom. Methods for producing wheat plants by crossing the new wheat variety ‘GA 04570-10E46’ with itself or another wheat variety and plants produced by such methods are also provided.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: March 28, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Jerry W. Johnson, G. David Buntin, James W. Buck
  • Publication number: 20170086343
    Abstract: The new variety ‘T-1101’ ripens around late May in southern Georgia and mid June in middle Georgia. The fruit of the new variety ‘T-1101’ are very large, firm, have good flavor and scar. The new variety ‘T-1101’ is vigorous with an estimated chilling requirement of about 400 to 450 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 23, 2017
    Applicant: University of Georgia Research Foundation, Inc.
    Inventor: D. Scott NeSmith
  • Publication number: 20170086344
    Abstract: The new variety ‘T-460’ ripens around mid June in southern Georgia and early July in middle Georgia. The fruit of the new variety ‘T-460’ are large, with good scar and very good color. The new variety ‘T-460’ is moderately vigorous with an estimated chilling requirement of about 500 to 550 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 23, 2017
    Applicant: University of Georgia Research Foundation, Inc.
    Inventor: D. Scott NeSmith
  • Publication number: 20170076622
    Abstract: Disclosed are various embodiments for assisting students in a development of critical thinking skills pertinent to solving problems. An educational system may access predefined education modules from memory that facilitate an interaction between a student and a user interface. The user input provided by the student is measured in real-time such that an analysis platform may conduct a real-time evaluation of the user input. A heat map that visually depicts skills of the student is generated and may be rendered in an administrative user interface that may be accessed by a teacher or similar personnel.
    Type: Application
    Filed: March 2, 2015
    Publication date: March 16, 2017
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: THOMAS P. ROBERSTON, GEORGIA W. HODGES, DAVID L. DUCREST, ANGELA K. BROWN
  • Patent number: 9587256
    Abstract: Provided herein are genetically engineered microbes that include at least a portion of a carbon fixation pathway, and in one embodiment, use molecular hydrogen to drive carbon dioxide fixation. In one embodiment, the genetically engineered microbe is modified to convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof at levels greater than a control microbe. Other products may also be produced. Also provided herein are cell free compositions that convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof. Also provided herein are methods of using the genetically engineered microbes and the cell free compositions.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: March 7, 2017
    Assignees: University of Georgia Research Foundation, Inc., North Carolina State University
    Inventors: Michael W. W. Adams, Robert M. Kelly, Aaron B. Hawkins, Angeli Lal Menon, Gina Lynette Pries Lipscomb, Gerrit Jan Schut
  • Patent number: 9566338
    Abstract: The present invention includes a composition including as one component a slurry matrix that is a liquid at room temperature and a gel at physiological pH, physiological salt concentrations and/or physiological temperatures and as a second component one or more antigens. Also include are methods of inducing an immune response in a subject and vaccinating a subject by administering such compositions.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: February 14, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Donald A. Harn, Rafaella Queiroz, Lisa McEwen
  • Publication number: 20170037071
    Abstract: Pt(IV) compounds include a mitochondria targeting moiety. One example of a Pt(IV) compound having a mitochondria targeting moiety is a Pt(IV) cisplatin-based compound. Upon reduction, the mitochondrial targeting moieties are released resulting in a Pt(II) therapeutic agent. Pt(IV) compounds including a mitochondria targeting moiety can be included in nanoparticles. The compounds or nanoparticles can be used to treat, for example, cancer.
    Type: Application
    Filed: April 8, 2015
    Publication date: February 9, 2017
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Shanta Dhar, Rakesh Pathak, Sean Marrache
  • Patent number: 9560826
    Abstract: Herein provided is a new wheat cultivar designated ‘GA 041293-11E54’ as well as the seeds, plants and derivatives of the new wheat variety ‘GA 041293-11E54’ (such as cultivars and hybrids related thereto). This cultivar is a high grain yielding, medium maturing, good test weight, medium height line that has good resistance to races of leaf rust and stripe rust in Georgia and the Southeast, powdery mildew, Hessian flies, and wheat soil-borne mosaic virus. Also provided are tissue cultures of the new wheat variety ‘GA 041293-11E54’ and the plants regenerated therefrom. Methods for producing wheat plants by crossing the new wheat variety ‘GA 041293-11E54’ with itself or another wheat variety and plants produced by such methods are also provided.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: February 7, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Jerry W. Johnson, G. David Buntin, James W. Buck
  • Patent number: 9549523
    Abstract: Herein provided is a new wheat cultivar designated ‘GA 04434-11E44’ as well as the seeds, plants and derivatives of the new wheat variety ‘GA 04434-11E44’ (such as cultivars and hybrids related thereto). This cultivar is a high grain yielding, medium-late maturing, good test weight, short height line that has good resistance to races of leaf rust and stripe rust in Georgia and the Southeast, powdery mildew, and wheat soil-borne mosaic virus. Also provided are tissue cultures of the new wheat variety ‘GA 04434-11E44’ and the plants regenerated therefrom. Methods for producing wheat plants by crossing the new wheat variety ‘GA 04434-11E44’ with itself or another wheat variety and plants produced by such methods are also provided.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: January 24, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Jerry W. Johnson, G. David Buntin, James W. Buck
  • Patent number: PP27782
    Abstract: An Abutilon plant named ‘RutAbut1’ has full blooms throughout the summer, short internode lengths, and large flowers that are yellow-orange with a red throat.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: March 14, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: John M. Ruter, Donglin Zhang, Allan M. Armitage, David A. Knauft, Suzzanne C. Tate, Kelly Preslar
  • Patent number: PP27881
    Abstract: An Abutilon plant named ‘RutAbut2’ has prolific quantities of large yellow flowers, a compact and more prostrate growth habit, shorter internodes, and has an extended duration of flowering.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: April 11, 2017
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: John M. Ruter, Donglin Zhang, Allan M. Armitage, David A. Knauft, Suzzanne C. Tate, Kelly Preslar
  • Patent number: PP28033
    Abstract: The new variety Schizachyrium scoparium ‘Seasons in the Sun’ is tough, adaptable, and drought tolerant with purple and green foliage and with an upright rounded growth habit with cascading foliage. The asexually reproduced variety is reliably propagated vegetatively.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: May 16, 2017
    Assignees: University of Georgia Research Foundation, Inc., The United States of America, as Represented by the Secretary of Agriculture
    Inventors: Carol D. Robacker, Melanie L. Harrison