Abstract: A method for forming a scaffold for use in fabricating a soft tissue implant, comprising: receiving, by a processor, soft tissue data corresponding to dimensions for a soft tissue, and a first and second weighting factor selected based on the dimensions of the soft tissue; transforming, by the processor, the soft tissue data, based on the first and second weighting factors, into a plurality of pin coordinates in a multi-dimensional space defining a shape of the scaffold for use in fabricating the soft tissue implant; and providing, by the processor, instructions to form the scaffold using weaving operations based on the pin coordinates.

Abstract: It is disclosed herein that ssAAV and scAAV vectors of the same serotype administered by injection into the cerebrospinal fluid (CSF) via the intracerebroventricular (ICV) or intrathecal (cisternal or lumbar) route exhibit different cellular tropisms in the central nervous system. Thus, a subject can be treated by injection into the CSF of ssAAV or scAAV vector encoding a therapeutic protein, such as an ssAAV9 or scAAV9 vector. The therapeutic protein can be targeted to specific cells using these vectors. In some embodiments, scAAV9 is utilized to achieve superior transduction in the hippocampus, cerebellum and cerebral cortex where both neurons, particularly Purkinje neurons, and glial cells (such as astrocytes) are transduced. In other embodiments, ssAAV9 is utilized to minimize transduction of astrocytes. In further embodiments, an immunosuppressive agent is also administered to the subject.

Abstract: Disclosed herein are compositions comprising a polymer and a metabolic inhibitor, as well as a method of using the composition to modulate an immune response. The composition may be produced in the form of a synthetic tissue for provision in a subject. The composition or synthetic tissue may further comprise additional therapeutic agents.

Abstract: A method of transmitting and receiving a signal at a terminal in a wireless communication system may be provided. A method of, at a terminal, transmitting and receiving a signal may comprise generating a first signal at transmitting end of the terminal and transmitting the generated first signal through an antenna and receiving a second signal through the antenna and transferring the second signal to a receiving end of the terminal. A differential circulator may be provided between the transmitting end and receiving end and the antenna, and the first signal may be transmitted and the second signal may be received at the same time based on the differential circulator.

Abstract: Systems, processes and devices are provided for wafer-level fabrication of a resonator. A process is provided that includes chemical etching of glass and silicon, high-temperature glassblowing, controlling assembly of at least one YIG sphere relative to a nest structure, and plasma assisted wafer bonding. The process can include formation of loop coils and spherical coils defined by the glassblowing process including inner and outer hemispherical structures. The inner hemispherical structure may provide loops to drive and detect resonance in YIG spheres. Processes discussed herein allow for placement of loops in close proximity (e.g., few microns) to ferrimagnetic elements. The outer hemisphere may provide harmonic magnetic coils for frequency tuning. Embodiments are also directed to a resonator including first and second wafer-level glass blown wafer stacks each with inner hemisphere and outer hemispheres.

Abstract: Provided is a chemical pretreatment system for waste fat, oil and grease (FOG), including: a catalyst preparation device; a first esterification reactor; a first separation device; a second separation device; an evaporation device set; a cooling device; and a methanol separation device. The first separation device is connected with an outlet of the first esterification reactor and connected with an inlet end of the second separation device. The second separation device is connected with an evaporation device by a first outlet and with another evaporation device by a second outlet. Outlets of multiple evaporation devices simultaneously connect with the cooling device which connects with the methanol separation device. A reflux device is connected with an outlet of the methanol separation device and also connected with the first esterification reactor.

Abstract: The present disclosure discloses a method for collaboratively controlling a multi-channel braking system of a mine hoist, including obtaining the abrasion loss of the brake shoe by detecting position information of the brake shoe of each of disc brakes in real time, dividing abrasion loss levels by determining different abrasion degrees of the brake shoe, formulating three braking force distributing modes: an average distribution, a proportional distribution, and an index distribution according to the abrasion loss levels, thereby dynamically adjusting a set braking pressure of each of the disc brakes, tracking and controlling the set braking pressure through the disc brakes by adopting a pressure closed-loop control method by utilizing a pressure signal feedback from an oil pressure sensor, implementing a collaborative braking control of the multi-channel braking system of the mine hoist based on the abrasion loss of the brake shoe.

Abstract: There is provided an apparatus for calculations based on a systolic array, comprising: a memory in which one or more operand data chunks are stored, a conveyor queue configured to shift the one or more operand data chunks in sequence and one or more synchronous processing units (SPUs) including one or more processing elements (PEs), and configured to access the operand data chunks shifted along the conveyor queue, wherein the one or more processing elements perform calculations based on the operand data chunks that the synchronous processing unit including each processing element has accessed.

Abstract: A two-dimensional continuous-discontinuous combined numerical approach for solid fracturing simulation, which includes: discretizing two-dimensional solid into finite elements to obtain a mapping linked list relationship between master-slave nodes; determining whether a crack is initiated according to whether the local stress of the finite element satisfies a strength criterion; if a crack initiates, activating a corresponding pre-embedded cohesive element, updating the mapping linked list relationship between the master-slave nodes at the same time, the cohesive element at the crack enters a yield state, and the mechanical behavior thereof is controlled by a strain softening constitutive curve; and, according to the mapping linked list relationship between the master-slave nodes, accumulating node forces and masses of the slave nodes onto the master node, and updating the velocity and the displacement of the master-slave nodes by adopting a governing equation.

Abstract: The present disclosure provides a device and method for recycling selective laser melting gradient powders, which comprises an ultrasonic powder suction device, a vertical support frame, the first vacuum pump, a sealing device, the second rotary motor, a powder storage bag, a vacuum box, a vibrating screen, a waste bin, the second vacuum pump, a powder conveying pipe, a cooling device, a water tank, and a spiral powder conveying pipe. This invention effectively reduces the risk of metal powder explosion through the cooling device's cooling. By multiple vibration screenings, this invention screens out the optimal gradient powders. The structure of this invention is simple, highly controllable, with easy-to-implement operating conditions, effectively avoiding the mixing and adhesion of different powders, improving the recovery utilization rate of gradient powders, and enabling the manufacturing of gradient materials with different compositions.

Abstract: A piezoelectric speaker includes: a peripheral rectangular frame having four sides; a central rectangular frame disposed on the peripheral rectangular frame, wherein the central rectangular frame has four corners and four sides, and the four corners are connected to the four sides of the peripheral rectangular frame; four central triangular cantilevers disposed within the central rectangular frame, wherein each of the central triangular cantilevers has a vibrating end and a fixed end opposite to the vibrating end, and each of the fixed ends of the central triangular cantilevers is connected to the four sides of the central rectangular frame, the four vibrating ends of the four central triangular cantilevers are close to each other, and the four central triangular cantilevers have different dimensions of their respective areas defined within the central rectangular frame; and four peripheral triangular cantilevers disposed between the peripheral rectangular frame and the central rectangular frame.

Abstract: A semiconductor device includes a channel structure, source region, a drain region, metal gate structure, and a self-assembled layer. The source region and the drain region are on opposite sides of the channel structure. A bottom surface of the source region is lower than a bottom surface of the channel structure, and a top surface of the source region is higher than a top surface of the channel structure. The metal gate structure covers the channel structure and between the source region and the drain region. The self-assembled layer is between the source region and the metal gate structure. The self-assembled layer is in contact with the bottom surface of the channel structure but spaced apart from the top surface of the channel structure.

Abstract: The present disclosure features, inter alia, a cyclic multifunctional linker, including at least two cleavable moieties; at least two connecting chains connected to the at least two cleavable moieties to provide a cyclic structure; and at least two linking groups, each linking group being bonded at one end to a connecting chain and being located between two cleavable moieties, and each linking group having a second end configured to bond to crosslinkable moieties. In the cyclic multifunctional linker, each connecting chain has at least two ends, and at least two of the connecting chains are each connected at each end to a cleavable moiety.

Abstract: A vehicle violation detection method and vehicle violation detection system are provided. The method includes the following steps. A video clip including a plurality of consecutive frames is obtained, wherein the video clip is generated through photographing an intersection by an image capture device. A traffic sign object corresponding to a traffic sign and a license plate object corresponding to a license plate are detected from each of the frames. According to a sign position of the traffic sign object and a plate position of the license plate object in each of the frames, vehicle behavior information of each of the frames is obtained. By conducting regression analysis to the vehicle behavior information of each of the frames, whether a vehicle violation event has occurred is determined.

Abstract: In some embodiments, devices for use as blood-brain barrier models are disclosed. The devices may include either a hydrogel component that surrounds a channel formed between a first opening and a second opening of the hydrogel component, or a hydrogel component that forms a groove. The devices may further include pericytes disposed in the channel or the groove, and endothelial cells may be disposed in the channel or the groove. The hydrogel component may include astrocytes (e.g., printed into the hydrogel component via projection stereolithography). Also disclosed are various methods of making and using these devices.

Abstract: Provided are: an antibody which specifically binds to and neutralizes USAG-1 or an antigen-binding fragment thereof; and a pharmaceutical composition containing the antibody or the antigen-binding fragment.

Abstract: Provided is a method of decomposing a crosslinked rubber that includes: a first decomposition step of decomposing a crosslinked rubber containing a diene rubber, using a catalyst represented by the following general formula (1), (2), or (3), where Mis ruthenium, molybdenum, etc., X1, X2, L1, L2, and L3 each independently represent a ligand, R1, R2, and R3 each independently represent hydrogen, an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aryl group, etc. (these groups may be substituted by one or more alkyl groups, halogens, alkoxy groups, etc.), L1 and L2, R1 and R2, and L1 and R1 may respectively bond with each other to form rings; and a second decomposition step of pyrolyzing a decomposition product obtained by the first decomposition step under an inert gas atmosphere and in the absence of a catalyst at a temperature of 300° C. to 450° C.

Abstract: Embodiments of the present disclosure provide three-dimensional (3D) printing methods, systems, and devices for target objects, and relate to a field of image data processing technology. The method includes performing a layering process to a 3D model of a target object and designing a printing path sequence, after each layer of the print is completed, according to a current layer 3D model and point cloud data of a single-layer 3D model corresponding to the current layer 3D model, performing the inspection of a height difference, a horizontal dimension difference and a void region in the printing, and according to the inspection result, performing timely feedback and adjustment, which can not only improve the professionalism, stability and efficiency of the printing, but also improve the similarity between the printed physical object and the target object, resulting in achieving a more accurate 3D printing.

Abstract: A system and method for measuring acceleration. The system comprises a diamond having a nitrogen-vacancy centre configured to emit fluorescence under optical illumination in presence of a radio frequency field tuned to a resonant frequency of the nitrogen-vacancy centre, and a magnet, wherein a distance between the magnet and the diamond varies in response to acceleration of the system, the change in distance altering a magnetic field experienced by the diamond. The system also comprises an optical sensor, the optical sensor configured to sense variation in fluorescence emitted by the diamond in response to the altered magnetic field for measuring acceleration.

Abstract: An example of a three-dimensionally printed object includes a bulk portion having a ferritic microstructure; and a site-specific alloyed section having a pearlite microstructure. The three-dimensionally printed object may be generated using different examples of a three-dimensional (3D) printing method. Each example of the 3D printing method utilizes a two-stage heat treatment.