Patents Assigned to The University
  • Visualizing sound with an electro-optical eardrum
    Patent number: 9786204
    Abstract: An educational system for visualizing sound by a student in a laboratory. The system includes a speaker powered by an audio amplifier. A function generator or a microphone controls the amplitude and frequency of pressure waves originating from the speaker. A model of the ear canal is suspended over the speaker, the model having a plastic pipe with two open ends and a membrane stretched taut over one of the open ends with constant tension. A mirror is affixed to the membrane, creating a mass-loaded membrane. A laser pointer emits light directed toward the mirror. A screen receives a light reflection pattern created by the light reflected from the mirror, with the model ear canal, speaker, membrane, and mirror placed equidistant between the screen and the laser pointer. The system is adapted to demonstrate hearing sensitivity to a deaf or hearing-impaired person in an educational setting.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: October 10, 2017
    Assignee: The University of Scranton
    Inventors: Nicholas P. Truncale, Michelle Graham
  • Method for producing peptides having azole-derived skeleton
    Patent number: 9783800
    Abstract: Object of the present invention is to develop an artificial synthesis system of various peptides having an azole derivative structure and develop a library of such peptides.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: October 10, 2017
    Assignee: The University of Tokyo
    Inventors: Hiroaki Suga, Yuki Goto, Yasuharu Kato
  • Synthesis of polymeric ionic liquids using a photochemical polymerization process
    Patent number: 9782748
    Abstract: Photo-initiated polymeric ionic liquids, methods of making and methods of using the same are disclosed. A preferred embodiment for making a photo-initiated polymeric ionic liquid (P-PIL) coated support, comprises: mixing at least one ionic liquid (IL) monomer with at least one photo-initiator; at least partially coating a support with the mixture; and exposing the coated support to UV light to form a photo-initiated polymeric ionic liquid (P-PIL) coated support.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: October 10, 2017
    Assignee: The University of Toledo
    Inventor: Jared L. Anderson
  • Coiled and non-coiled twisted nanofiber yarn torsional and tensile actuators
    Patent number: 9784249
    Abstract: Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate torsional and/or tensile actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize non-coiled or coiled yarns and can be either neat or comprising a guest. Devices comprising these artificial muscles are also described.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: October 10, 2017
    Assignee: The Board of Regents, The University of Texas System
    Inventors: Na Li, Carter S. Haines, Marcio D. Lima, Monica Jung De Andrade, Shaoli Fang, Jiyoung Oh, Mikhail E. Kozlov, Dongseok Suh, Ray H. Baughman
  • Microfluidic oscillator pump utilizing a ring oscillator circuit implemented by pneumatic or hydraulic valves
    Patent number: 9784258
    Abstract: Microfluidic oscillator circuits and pumps for microfluidic devices are provided. The microfluidic pump may include a plurality of fluid valves and a microfluidic oscillator circuit having an oscillation frequency. The fluid valves may be configured to move fluids. Each fluid valve may be connected to a node of the microfluidic oscillator circuit. The pumps may be driven by the oscillator circuits such that fluid movement is accomplished entirely by circuits on a microfluidic chip, without the need for off-chip controls.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: October 10, 2017
    Assignee: The Regents of The University of California
    Inventors: Elliot E. Hui, Philip N. Duncan, Transon V. Nguyen
  • Systems and methods for radiation treatment planning using combined imaging and treatment dose
    Patent number: 9782607
    Abstract: Systems and methods for radiation treatment planning that integrate the MV therapeutic radiation dose imparted to a subject together with the kV imaging radiation dose imparted to a subject during radiation therapy are provided. For instance, dose optimization is based on the combined effect of both a kV imaging dose that is imparted to the subject during the image guided radiation treatment procedure and the therapeutic dose delivered to the subject by a treatment radiation source, such as an MV source. Using this optimization, the kV beam and MV beam are equally treated as radiation producing sources and are thus optimized together at the treatment planning stage to produce a patient treatment plan that optimally uses the kV imaging dose. Thus, the kV beam is treated both as an additional source of therapeutic radiation and as a tool for imaging the subject.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: October 10, 2017
    Assignee: The University of Chicago
    Inventors: Rodney Wiersma, Zachary Grelewicz
  • Treatment of cancer and benign proliferative disorders
    Patent number: 9782409
    Abstract: Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign proliferative disorders (warts) or in the prevention of the development of cancer. Pharmaceutical compositions formulated for topical application comprising a therapeutically effective amount of lopinavir or a therapeutically effective amount lopinavir and ritonavir in a pharmaceutically acceptable vehicle are also provided. Also disclosed are methods of treating a patient having an HPV related dysplasia of the cervix comprising administering to said patient a therapeutically effective dose of the disclosed pharmaceutical compositions.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: October 10, 2017
    Assignee: The University of Manchester
    Inventors: Ian Hampson, Lynne Hampson
  • Non-dispersive process for oil recovery
    Patent number: 9782726
    Abstract: A method of recovering one or more insoluble oils from a liquid source using one or more membrane or membrane contactors, comprising the steps of: pumping the liquid source comprising the one or more oils to the membranes or membrane contactors, contacting the liquid source with a first surface of the membrane or membrane contactors, coalescing the one or more oils within the liquid source onto the first surface of the membrane contactors, pumping one or more recovery fluids through the membrane or membrane contactors in contact with the second surface of the membrane or membrane contactors, and removing a first stream of oil coalesced from the second surface of the membranes or membrane contactors.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: October 10, 2017
    Assignee: Board of Regents, The University of Texas System
    Inventors: Frank Seibert, Stacy S. Truscott, Stephen William Briggs, Peter B. Kipp
  • Lanthanide ion complexes and imaging method
    Patent number: 9783554
    Abstract: A lanthanide complex, method of forming and method of using the lanthanide complex as a near-infrared luminescent material are described. The complex includes at least one lanthanide ion and at least one polydentate ligand derived from a molecule having the general formula of Structure 2: where: E represents a heteroatom or heteroatom-containing group and R1-R8 are independently selected from H, —OH, —NH2, —SO3H, —CO2H, halides, optionally substituted organic groups; and conjugated linking groups which link two of the polydentate ligands of Structure 2 together.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: October 10, 2017
    Assignee: The University of Akron
    Inventors: Yi Pang, Qinghui Chu
  • Digestion of waste activated sludge with algae
    Patent number: 9783442
    Abstract: Phagotrophic algae are used in connection with aerobic or anaerobic digestion of solids, especially waste activated sludge (WAS), to more efficiently digest solids and to meet, over a shorter period of time, volatile solids standards and specific oxygen uptake rate requirements as well as pathogen reduction requirements.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: October 10, 2017
    Assignees: Ovivo Inc., The University of Akron
    Inventors: Lu-Kwang Ju, Hiren K. Trivedi
  • AUTHENTICATION SYSTEM AND METHOD
    Publication number: 20170286648
    Abstract: An object of the present invention is to provide an authentication system and method which can reduce a burden on a user while ensuring security by using a combination of a plurality of authentication methods.
    Type: Application
    Filed: August 24, 2015
    Publication date: October 5, 2017
    Applicant: The University of Tokyo
    Inventors: Rie YAMAGUCHI, Hideki NAKAYAMA, Tatsuya HARADA, Daisuke SAKAMOTO
  • Proxisome Proliferator Activated Receptor (PPAR) Compounds and Methods of Using the Same
    Publication number: 20170283385
    Abstract: Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.
    Type: Application
    Filed: May 12, 2017
    Publication date: October 5, 2017
    Applicant: The University of Toledo
    Inventors: Bruce E. Heck, Dong Hyun Kim, Paul Erhardt, Brian Kress
  • BLOCKING MONOCLONAL ANTIBODIES TO AGR2 AND ITS RECEPTOR C4.4A
    Publication number: 20170283509
    Abstract: Provided herein are monoclonal antibodies that recognize, bind to, and block interactions of other molecules with AGR2 and C4.4A. Also provided herein are methods of using said antibodies to treat cancer.
    Type: Application
    Filed: September 8, 2015
    Publication date: October 5, 2017
    Applicant: Board of Regents, The University of Texas System
    Inventors: Craig D. LOGSDSON, Vijaya RAMACHANDRAN, Thiruvengadam ARUMUGAM
  • Semi-automated heart valve morphometry and computational stress analysis from 3D images
    Patent number: 9779496
    Abstract: A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: October 3, 2017
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Benjamin M. Jackson, Robert C. Gorman, Joseph H. Gorman, Alison M. Pouch, Chandra M. Sehgal, Paul A. Yushkevich, Brian B. Avants, Hongzhi Wang
  • Recovery of regenerant electrolyte
    Patent number: 9776137
    Abstract: Methods, systems and compositions for recovery of regenerant ions from spent regenerant solution by utilization of electrodialysis are provided. For example, in certain aspects methods for separating spent regenerant using an electrodialysis system comprising selective membranes are described. Furthermore, the invention provides methods for treating a friable solid ion-removal material to prevent fragmentation during regeneration.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: October 3, 2017
    Assignee: Board of Regents, The University of Texas System
    Inventor: Thomas A. Davis
  • Low fat chocolate
    Patent number: 9775367
    Abstract: The application describes comestible products comprising a water-in-oil emulsion, the water-in-oil emulsion comprising cocoa butter and a fat-crystal stabilised aqueous phase dispersed substantially through the cocoa butter continuous phase and optionally one or more additional ingredients of chocolate. Hydrocolloids, such as gelative or carrageenan are typically used to stabilise the aqueous phase. Methods of making comestible products are also provided.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: October 3, 2017
    Assignee: The University of Birmingham
    Inventors: Ian Timothy Norton, Philip William Cox, Benjamin Jean Didier Le Reverend, Jennifer Elizabeth Norton
  • Synthesis of hyperbranched polyacrylates by emulsion polymerizsation of inimers
    Patent number: 9777082
    Abstract: A method for the production of hyperbranched polyacrylates includes the step of reacting acrylic inimers through controlled living polymerization in aqueous conditions. The inimers may have the formula: Wherein X is a halogen, a thiocarbonylthio or nitroxide group, and R is hydrogen, methyl, dodecyl, and groups containing mesogenin substituents, fluorocarbon substituents, siloxane substituents and oxyethylene substituents. In particular, the aqueous condition is emulsion or miniemulsion. The polymerization may be reverse ATRP, SN&RI and AGET polymerization or RAFT polymerization (with thiocarbonylthio X groups) or nitroxide mediated polyeization (with nitroxide X groups).
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: October 3, 2017
    Assignee: The University of Akron
    Inventors: Coleen Pugh, Guillermina Garcia
  • Multi-layered 3D printed laser direct structuring for electrical interconnect and antennas
    Patent number: 9777380
    Abstract: A multi-layered 3D printed laser direct structuring method and apparatus for electrical interconnect and antennas. 3D printed components can be configured with structurally integrated metal connections (e.g., bulk highly conductive metal) that traverse multiple layers (some embedded and others external) of a structure fabricated using an additive manufacturing system enhanced with an iterative laser activated plating processes, which includes a novel well side-wall vertical interconnect.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: October 3, 2017
    Assignee: Board of Regents, The University of Texas System
    Inventors: Eric MacDonald, David Espalin, Ryan Wicker
  • Methods for Treating GI Syndrome and Graft versus Host Disease
    Publication number: 20170273987
    Abstract: We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.
    Type: Application
    Filed: February 20, 2017
    Publication date: September 28, 2017
    Applicants: Sloan Kettering Institute for Cancer Research, Board of Regents, The University of Texas System
    Inventors: Jimmy Andrew Rotolo, Richard N. Kolesnick, Renata Pasqualini, Wadih Arap
  • THREE-DIMENSIONAL ARTIFICIAL TISSUE, METHOD FOR PRODUCING THE SAME, THREE-DIMENSIONAL ARTIFICIAL TISSUE PERFUSION DEVICE, AND DRUG EVALUATION METHOD USING THREE-DIMENSIONAL ARTIFICIAL TISSUE
    Publication number: 20170274121
    Abstract: The method for producing a three-dimensional artificial tissue is a method in which a three-dimensional artificial tissue extending in a predetermined direction is produced. The method includes: preparing a device including a culture tank having a culturing space surrounded by sidewalls, and a flow channel-forming member that penetrates through the sidewalls that face each other and is suspended in the culturing space along a predetermined direction; culturing cells in the culturing space and thereby forming a three-dimensional artificial tissue through which the flow channel-forming member penetrates; and removing the flow channel-forming member from the three-dimensional artificial tissue and thereby forming a perfusion flow channel that penetrates through the three-dimensional artificial tissue.
    Type: Application
    Filed: June 30, 2015
    Publication date: September 28, 2017
    Applicant: The University of Tokyo
    Inventors: Shoji TAKEUCHI, Yuya MORIMOTO, Nobuhito MORI