Abstract: Embodiments of the invention are directed to a device having one or more electromagnetic components embedded in an anisotropic metamaterial (AM) comprising an array of asymmetric unit cells comprising a substrate forming a plurality of channels or spaces having at least one material with different electromagnetic properties included in the channels or spaces in the first material forming an anisotropic metamaterial.
Type:
Grant
Filed:
June 23, 2015
Date of Patent:
September 19, 2017
Assignee:
Board of Regents, The University of Texas System
Abstract: Some aspects of the invention include methods of treating a patient who has or is at risk of developing kidney disease, methods of selecting a suitable regimen for the prevention or treatment of kidney disease, and to methods of monitoring the effectiveness of a treatment regimen for the prevention or treatment of kidney disease. Other aspects of the invention include medical uses of a binding partner for an anti-IQCJ antibody, and methods of preventing or treating kidney disease in a subject using such binding partners. Still other aspects of the invention include devices for the extracorporeal treatment of a patient's blood.
Abstract: A flame resistant polymer is obtained by reacting polyacrylonitrile with amine and nitro compounds, the polyacrylonitrile being polymerized by aqueous suspension polymerization using a redox initiator and containing an S component at an amount of 3,000 ?g/g or less. A PAN-based polymer in which both yarn producing properties and flame resistance are improved can be realized.
Abstract: This invention is a device that provides feedback controlled pressure output that delivers a highly controlled and accurate air stimulus into the larynx for diagnostic use. The device is designed to be significantly more accurate, safer for the patient, and highly modular for easy future modifications compared to previously available commercial devices.
Type:
Application
Filed:
November 19, 2014
Publication date:
September 14, 2017
Applicant:
The University of Toledo
Inventors:
Reginald Baugh, Ali Hassani, Payam Entezami
Abstract: Sulfur containing, hydroxyl-telechelic PIBs, hydrolytically and oxidatively resistant, biocompatible and biostable polyurethanes (PUs) made therefrom, and methods for making both are disclosed. Well-defined hydroxyl telechelic PIBs are synthesized by a thiol-ene click photochemical reaction between PIBs carrying unsaturated end groups and 2-mercaptoethanol (HS—CH2CH2—OH). This regioselective process affords HO—CH2CH2—S-PIB-S—CH2CH2—OH (abbreviated herein as HO—S-PIB-S—OH) in high yield. In some embodiments, these HO—S-PIB-S—OH polymers may be reacted with diisocyanates and a chain extender to form sulfur containing PIB-based PUs. These sulfur containing PIB-based PUs have been found to have properties and chemical stability that are very similar to that of PUs made from di-hydroxyl terminated PIBs (OH-PIB-OHs) without sulfur, but have surprisingly increased creep resistance and are easier and less expensive to make.
Type:
Application
Filed:
August 26, 2015
Publication date:
September 14, 2017
Applicant:
The University of Akron
Inventors:
Joseph KENNEDY, Kalman TOTH, Nihan NUGAY, Turgut NUGAY
Abstract: Systems and methods are disclosed that describe a MEMS device and a method of sensing based on a consensus algorithm. The MEMS device is a sensor comprising multiple piezoelectric layers attached to a microcantilever. It can be used to sense deflections or variations in corresponding parameters of systems in micro- and nano-scales. Multiple piezoelectric elements on a microcantilever can provide a more accurate measurement of the microcantilever's deflection. The device can eliminate bulky laser sensors in SPMs and provide additional use as a biosensor, or chemical sensor at the micro- and nano-scale. The consensus sensing algorithm can provide added robustness into the system. If one of the sensing elements or electrodes fails during a sensing process, other elements can compensate and allow for near zero-error measurement.
Type:
Grant
Filed:
June 2, 2016
Date of Patent:
September 12, 2017
Assignee:
The Board of Trustees of The University of Alabama
Abstract: An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 59.
Type:
Grant
Filed:
November 18, 2015
Date of Patent:
September 12, 2017
Assignee:
The University of Western Australia
Inventors:
Stephen Donald Wilton, Sue Fletcher, Abbie Adams, Penny Meloni
Abstract: A novel method of fabricating carbon nanotube sheet scrolled fiber and fiber tows (carbon, graphite, glass, natural polymer, synthetic polymer, metallic, silicon carbide, Kevlar, etc.) in composites with improved interfacial shear strength, compressive strength, yield strength, stiffness and toughness has been reported. Single or multiple layers of carbon nanotube sheet, with a bias/wrapping angle of 0° and 90°, has been scrolled around single fiber and fibers tows to improve the above mentioned mechanical properties of the matrix surrounding the fiber. Other common methods of growing CNTs directly on the fibers actually damage the fiber surface during the required precursor deposition and CNTs growth process. This demonstrated solid-state method overcomes such known problems. The CNTs sheet scrolled fiber is embedded into the polymer matrix exhibits significant (80%) increase in interfacial shear strength, compressive strength and toughness.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
September 12, 2017
Assignee:
The Board of Regents, The University of Texas System
Inventors:
Hongbing Lu, Ray H. Baughman, Mohammad H. Haque, Shaoli D. Fang
Abstract: The invention provides a method for preparing a compound or a product having one or more characteristics that meet or exceed a user specification, the process comprising the step of selecting a first combination of chemical inputs, optionally together with physical inputs, and supplying those inputs to a reaction space, thereby to generate a first product; analyzing one or more characteristics of the product generated; comparing the one or more characteristics against a user specification; using a genetic algorithm selecting a second combination of chemical inputs, optionally together with physical inputs, wherein the second combination differs from the first combination, and supplying those inputs to the reaction space, thereby to generate a second product; analyzing one or more characteristics of the second product generated; comparing the one or more characteristics generated against the user specification; repeating the selecting and analyzing steps for further individual combinations of chemical and/or p
Type:
Grant
Filed:
May 24, 2013
Date of Patent:
September 12, 2017
Assignee:
The University Court of The University of Glasgow
Abstract: Lipid particles containing a nucleic acid, devices and methods for making the lipid particles, and methods for using the lipid particles.
Type:
Grant
Filed:
May 4, 2012
Date of Patent:
September 12, 2017
Assignee:
The University of British Columbia
Inventors:
Pieter R. Cullis, Nathan M. Belliveau, Carl Lars Genghis Hansen, Jens Huft, James Taylor, Andre Wild, Stuart Malcolm, Ismail Hafez, Alex Leung, David Walker
Abstract: Tools and techniques for estimating a probability that a patient is bleeding or has sustained intravascular volume loss (e.g., due to hemodialysis or dehydration) and/or to estimate a patient's current hemodynamic reserve index, track the patient's hemodynamic reserve index over time, and/or predict a patient's hemodynamic reserve index in the future. Tools and techniques for estimating and/or predicting a patient's dehydration state. Tools and techniques for controlling a hemodialysis machine based on the patient's estimated and/or predicted hemodynamic reserve index.
Type:
Grant
Filed:
July 20, 2012
Date of Patent:
September 12, 2017
Assignees:
Flashback Technologies, Inc., The Regents of The University of Colorado, a body corporate
Inventors:
Gregory Zlatko Grudic, Steven Lee Moulton, Isobel Jane Mulligan
Abstract: A computer-based detection tool for detecting whether content within a given document is common to content within a plurality of other, existing documents, the detection tool comprising: a character string recognizer for recognizing character strings in the content of the given document; a character string distinguisher for distinguishing main character strings and auxiliary character strings in the recognized character strings by reference to a closed list of main character strings; an encoder for encoding the content of the given document by assigning one or more digits to each main character string and one or more digits to auxiliary character strings; and a matcher for matching a plurality of n-digit streams from within the encoded content with any corresponding n-digit streams within previously-encoded content of the one or more other documents. The character strings may be encoded as a bit-stream.
Abstract: Apparatus and methods are provided for applying negative pressure to tissues of a patient that are transmitted to the vertebral venous system of the patient and thereby lowering intracranial pressure. Intracranial pressure is thus lowered easily without increasing the work of breathing, without needing to be intubated, and without breathing through a valve in patients with elevated increased intracranial pressure.
Type:
Grant
Filed:
April 8, 2013
Date of Patent:
September 12, 2017
Assignee:
Board of Regents, The University of Texas System
Abstract: The present invention relates to compositions and methods of use thereof for inhibiting mutant HTT mRNA transcription or CAG-expanded HTT protein expression in a cell, comprising contacting the cell with an effective amount of an oligomer targeting a differentiating polymorphism, wherein the differentiating polymorphism is selected from rs72239206, rs363107, rs362313, rs2530595, rs113407847. Specific oligomer sequences are also provided.
Type:
Application
Filed:
September 18, 2015
Publication date:
September 7, 2017
Applicant:
The University of British Columbia
Inventors:
Amber L. Southwell, Christopher Kay, Michael R. Hayden, Nicholas S. Caron
Abstract: The polynucleotide construct of (1) or (2) below is used to perform ribosome display, CIS display and/or mRNA display in order to screen a Fab against an antigen of interest: (1) a polynucleotide construct which monocistronically comprises a ribosome-binding sequence, Fab first chain-coding sequence, linker peptide-coding sequence, Fab second chain-coding sequence and scaffold-coding sequence in this order, and further comprises at its 3?-end a structure necessary for maintaining a complex with the Fab encoded by itself; and (2) a polynucleotide construct which comprises a Fab first chain-expressing cistron and a Fab second chain-expressing cistron each containing a ribosome-binding sequence, a Fab first chain-coding sequence or Fab second chain-coding sequence, and a scaffold-coding sequence in this order, the first Fab-expressing cistron further comprising at its 3?-end a ribosome stall sequence, said Fab second chain-expressing cistron further comprising at its 3?-end a structure necessary for maintaining
Type:
Grant
Filed:
November 30, 2011
Date of Patent:
September 5, 2017
Assignees:
Mitsubishi Tanabe Pharma Corporation, The University of Tokyo
Abstract: A method of using a fluidics apparatus for lysing a cell. In the method, the cell is placed in a fluid sample contacting a substrate surface. The method further includes providing surface acoustic waves (SAWs) at the substrate surface, causing cell lyses.
Type:
Grant
Filed:
May 27, 2016
Date of Patent:
September 5, 2017
Assignee:
The University Court of the University of Glasgow
Inventors:
Rab Wilson, Jonathan M. Cooper, Julien Reboud
Abstract: Liquid or solid electrolyte compositions are described that comprise a homogeneous solvent system and an alkali metal salt dissolved in said solvent system. The solvent system may comprise a fluoropolymer, having one or two terminal carbonate groups covalently coupled thereto. Batteries containing such electrolyte compositions are also described.
Type:
Grant
Filed:
March 31, 2014
Date of Patent:
September 5, 2017
Assignees:
The University of North Carolina at Chapel Hill, The Regents of the University of California
Inventors:
Joseph M. DeSimone, Ashish Pandya, Dominica Wong, Nitash P. Balsara, Jacob Thelen, Didier Devaux
Abstract: A system for disinfecting a fluid, including: a flow cell including one or more inlet ports and one or more outlet ports, wherein the flow cell is configured to communicate a fluid containing a biological contaminant from the one or more inlet ports to the one or more outlet portions through an interior portion thereof; and one or more point radiation sources disposed about the flow cell, wherein the one or more point radiation sources are operable for delivering radiation to the biological contaminant; wherein an interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources; and wherein the interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources such that a radiation intensity is uniform throughout the interior portion of the flow cell. In one exemplary embodiment, the flow cell is an integrating sphere.
Type:
Grant
Filed:
June 17, 2011
Date of Patent:
September 5, 2017
Assignees:
AquiSense Technologies LLC, The University of North Carolina at Charlotte
Inventors:
Edward Brittain Stokes, Jennifer Godwin Pagan, Thomas Andrew Schmedake
Abstract: A system combines hyperthermia and radiation treatments in a single treatment modality by using a radioactive seed having magnetic, ferromagnetic, or ferrimagnetic properties.
Type:
Grant
Filed:
April 21, 2017
Date of Patent:
September 5, 2017
Assignee:
The University of Toledo
Inventors:
E. Ishmael Parsai, Diana Shvydka, Gregory Warrell
Abstract: An example method for controlling an AC electrical machine can include providing a PWM converter operably connected between an electrical power source and the AC electrical machine and providing a neural network vector control system operably connected to the PWM converter. The control system can include a current-loop neural network configured to receive a plurality of inputs. The current-loop neural network can be configured to optimize the compensating dq-control voltage. The inputs can be d- and q-axis currents, d- and q-axis error signals, predicted d- and q-axis current signals, and a feedback compensating dq-control voltage. The d- and q-axis error signals can be a difference between the d- and q-axis currents and reference d- and q-axis currents, respectively. The method can further include outputting a compensating dq-control voltage from the current-loop neural network and controlling the PWM converter using the compensating dq-control voltage.
Type:
Grant
Filed:
August 5, 2014
Date of Patent:
September 5, 2017
Assignee:
Board of Trustees of The University of Alabama
Inventors:
Shuhui Li, Michael Fairbank, Xingang Fu, Donald Wunsch, Eduardo Alonso