Patents Assigned to The University
  • Polymers functionalized with ion-specific recognition elements
    Patent number: 9585910
    Abstract: Polymeric compounds containing polymer backbones functionalized with ion-specific recognition elements and methods for the use of these compounds are described herein. The polymeric compounds may contain multiple types of ion-specific recognition elements depending on a specific application. The polymeric compounds can be used to remove ionic species from a solution, for example, in separations applications in which a single or multiple types of ionic species are desired to be removed from the solution.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: March 7, 2017
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jonathan L. Sessler, Christopher W. Bielawski, Abdullah Aydogan, Daniel J. Coady
  • Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor 1 (IGF-1)
    Patent number: 9587024
    Abstract: The present invention provides an antibody or antigen-binding fragment thereof that binds ?v?3 integrin, as well as methods of use in the treatment of diseases and disorders.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: March 7, 2017
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: David Clemmons, Laura Maile, Michael Naso, Francis J. Carr, Timothy D. Jones, Simon William Keen
  • Therapeutic agent for emphysema and COPD
    Patent number: 9585930
    Abstract: The invention described herein relates to methods of treating emphysema and COPD with a GHK tripeptide. The invention further relates to methods of determining the state of the lungs using biomarkers described herein.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: March 7, 2017
    Assignees: Trustees of Boston University, The University of British Columbia
    Inventors: Avrum Spira, Marc Lenburg, Joshua Campbell, Dimitri Petchkovski, Darryl Andrew Knight, James Cameron Hogg, Julie Erin Zeskind Gil
  • Polyisobutylene-based polyurethanes containing organically modified montmorillonite
    Patent number: 9587069
    Abstract: The present invention generally relates to polyurethanes and polyurethane prepolymers having improved mechanical properties over ordinarily produced polyurethanes or polyurethane prepolymers. Such polyurethanes and prepolymers include very small amounts of organically-modified layered clays, and more specifically, less than 1 weight percent, based upon the total polymer composition, of a layered clay exfoliated with organic quaternary ammonium salts having alkyl substituents, wherein at least one of the alkyl substituents carries an —NH2 group.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: March 7, 2017
    Assignee: The University of Akron
    Inventors: Joseph Kennedy, Nihan Nugay, Turgut Nugay
  • Methods and compositions for measuring cell permeability
    Patent number: 9588106
    Abstract: Embodiments of the present invention provide an in vitro assay that measures cell monolayer permeability. The assay utilizes detection of a binding pair initially separated by the cell monolayer as a qualitative and quantitative measure of the permeability of the monolayer. In certain embodiments, the assay is performed in the presence of a test substance that may or may not affect cell permeability. In particular aspects, the assay is performed on a substrate that is elastic. One can also assay spatial resolution of local changes by visualizing regional variations of the cell monolayers.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: March 7, 2017
    Assignee: The University of Chicago
    Inventors: Oleksii Dubrovskyi, Konstantin Birukov
  • Use of nitrated lipids for treatment of side effects of toxic medical therapies
    Patent number: 9585855
    Abstract: The present invention relates to methods of treating the side effects of a toxic medical therapy using nitrated lipids. In particular, the methods comprise the use of nitrated fatty acids or esters thereof to treat side effects, including organ system damage, caused by chemotherapy, radiotherapy, and the administration of other toxic agents.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: March 7, 2017
    Assignee: The University of Utah Research Foundation
    Inventor: Tianxin Yang
  • Compositions Comprising Citrate and Applications Thereof
    Publication number: 20170056435
    Abstract: In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells. In some embodiments, the citrate-presenting composition is provided to the bone cells at a first stage of cell development selected to obtain a first cell differentiation or phenotype progression. Additionally, in some cases, a second citrate-presenting composition is further provided to the bone cells at a second stage of cell development selected to obtain a second cell differentiation or phenotype progression.
    Type: Application
    Filed: November 11, 2016
    Publication date: March 2, 2017
    Applicant: Board of Regents, The University of Texas System
    Inventor: Jian Yang
  • PHOTODETECTOR UTILIZING QUANTUM DOTS AND PEROVSKITE HYBRIDS AS LIGHT HARVESTERS
    Publication number: 20170062139
    Abstract: A broad-band photodetector utilizes perovskite hybrid material and quantum dots as light harvesters. In particular, the photodetector is configured so that the structural defects on the surface of a quantum dot layer are passivated with perovskite hybrid material. As a result, the trap states on the surface of the quantum dot material is reduced, allowing leakage currents in the quantum dot material to be significantly reduced. As such, the photodetector is able to achieve broad-band operation, with enhanced photoresponsitivity and detectivity.
    Type: Application
    Filed: August 30, 2016
    Publication date: March 2, 2017
    Applicant: The University of Akron
    Inventors: Xiong Gong, Chang Liu
  • FLEXIBLE TACTILE SENSORS AND METHODS OF MAKING
    Publication number: 20170059426
    Abstract: A tactile sensor includes a first insulating layer having a first array of electrically conductive strips embedded therein and extending in a first direction. An intermediate layer of conductive soft polymer material is positioned above the first insulating layer and the first array of said electrically conductive strips. A second insulating layer having a second array of electrically conductive strips embedded therein, which extend in a second direction which is different than the first direction, is positioned above the intermediate layer. The first array of electrically conductive strips are connected to the second array of electrically conductive strips, and both the first and second array of electrically conductive strips are also connected to an impedance measuring device.
    Type: Application
    Filed: September 20, 2016
    Publication date: March 2, 2017
    Applicant: The University of Akron
    Inventors: Jae-Won Choi, Erik Daniel Engeberg, Morteza Vatani, Ho-Chan Kim, Thomas Swiger
  • Microfabricated Surfaces for The Physical Capture of Insects
    Publication number: 20170055512
    Abstract: Novel devices and methods of capturing, controlling and preventing infestation of insects using microfabricated surfaces are provided. In particular, a mechanism of insect capture inspired by the microstructures of the leaf surfaces of plants and the key features of those surfaces with respect to the capture and control of pests have been determined and engineered into a variety of microfabricated surfaces capable of reproducing the effectiveness of these physical capture methods.
    Type: Application
    Filed: September 19, 2016
    Publication date: March 2, 2017
    Applicants: The Regents of the University of California, The University of Kentucky Research Foundation
    Inventors: Catherine Loudon, Robert Corn, Megan Szyndler, Kenneth F. Haynes, Michael F. Potter
  • ANTIMICROBIAL SURFACE
    Publication number: 20170057998
    Abstract: The invention relates to an antimicrobial surface, in particular a surface functionalised with a peptide comprising an antimicrobial moiety. The invention comprises a surface functionalised with a peptide comprising an antimicrobial moiety and a binder moiety, wherein the peptide is immobilized on the surface by electrostatic interactions between the binder moiety and the surface. Further provided is a medical device, a peptide and a method for the immobilization of a peptide.
    Type: Application
    Filed: February 25, 2015
    Publication date: March 2, 2017
    Applicants: The University of Birmingham, The Secretary of State for Defence of the United Kingdom of Great Britain and Northern Ireland
    Inventors: Artemis Stamboulis, Felicity Jane de Cogan, Robert Scott, Anna Frances Acushia Peacock
  • SYSTEMS AND METHODS FOR REMOVING REVERBERATION FROM AUDIO SIGNALS
    Publication number: 20170061984
    Abstract: Disclosed herein are systems and methods for removing reverberation from signals. The systems and methods can be applicable to audio signals, for example, to voice, musical instrument sounds, and the like. Signals such as the vowel sounds in speech and the sustained portions of many musical instrument sounds can be composed of a fundamental frequency component and a series of harmonically related overtones. The systems and methods can exploit the intrinsically high degree of mutual correlation among the overtones. When such signals are passed through a reverberant channel, the degree of mutual correlation among the partials can be reduced. An inverse channel filter for the removal of reverberation can be found by employing an adaptive filter technique that maximizes the cross-correlation among signal overtones.
    Type: Application
    Filed: September 2, 2016
    Publication date: March 2, 2017
    Applicant: The University of Rochester
    Inventors: Mark F. Bocko, Sarah Smith
  • ANALYSIS OF GENOMIC DNA, RNA, AND PROTEINS IN EXOSOMES FOR DIAGNOSIS AND THERANOSIS
    Publication number: 20170059572
    Abstract: The present invention provides that exosomes from human body fluid samples contain double stranded genomic DNA that spans all chromosomes and may be used to determine the mutation status of genes of interest in diseases, such as cancer. Furthermore, the present invention provides the use of exosomes to produce therapeutic proteins and for their use in therapy as well as the detection of cancer cell-derived exosomes to diagnose cancer and monitor therapeutic response.
    Type: Application
    Filed: December 4, 2014
    Publication date: March 2, 2017
    Applicant: Board of Regents, The University of Texas System
    Inventors: Raghu KALLURI, Sónia MELO
  • NOVEL CYTOCHROME P450 FUSION PROTEIN
    Publication number: 20170058267
    Abstract: This disclosure relates to the isolation of a nucleic acid molecule[s] that encode a novel cytochrome P450 and an oxidoreductase from a Papaver somniferum [P. somniferum] cultivar, transgenic cells transformed with said nucleic acid molecule and sequence variants thereof; and including methods for the production of intermediates in the production of morphinans.
    Type: Application
    Filed: May 15, 2015
    Publication date: March 2, 2017
    Applicants: The University of York, Sun Pharmaceutical Industries (Australia) Pty Ltd
    Inventors: Thilo Winzer, Ian Graham, Tracy Carol Walker
  • Therapies for Cancer Using RLIP76
    Publication number: 20170059556
    Abstract: The present invention is a composition identified as a region of ralA binding protein 1, wherein the region neighbors a membrane-associated portion of the ralA binding protein 1, reduces transport activity and membrane association of the ralA binding protein 1 and kills cells undergoing uncontrolled cell growth in a subject that has cells undergoing uncontrolled cell growth. The region is used to generate medicines that kill malignant cells and tumorigenic cells. Medicines may be in the form of antibodies, si-RNA and small molecules that recognize the region.
    Type: Application
    Filed: November 10, 2016
    Publication date: March 2, 2017
    Applicant: Board of Regents, The University of Texas System
    Inventors: Sanjay Aswasthi, Sharad S. Singhal, Sushma Yadav
  • Real-time object analysis with occlusion handling
    Patent number: 9582895
    Abstract: A method includes the following steps. A video sequence including detection results from one or more detectors is received, the detection results identifying one or more objects. A clustering framework is applied to the detection results to identify one or more clusters associated with the one or more objects. The clustering framework is applied to the video sequence on a frame-by-frame basis. Spatial and temporal information for each of the one or more clusters are determined. The one or more clusters are associated to the detection results based on the spatial and temporal information in consecutive frames of the video sequence to generate tracking information. One or more target tracks are generated based on the tracking information for the one or more clusters. The one or more target tracks are consolidated to generate refined tracks for the one or more objects.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: February 28, 2017
    Assignees: International Business Machines Corporation, The University of Queensland
    Inventors: Lisa M. Brown, Sayed Ali Emami, Mehrtash Harandi, Sharathchandra U. Pankanti
  • Three-electrode buffer generator and method
    Patent number: 9580822
    Abstract: An electrodialytic buffer generator is described. The buffer generator may include a central buffer-generating channel having an inlet and outlet, a second chamber, and a third chamber. The buffer-generating channel, the second chamber, and the third chamber may each include an electrode. The buffer generator may also include a first ion exchange barrier and a second ion exchange barrier. The first ion exchange barrier can be disposed between the second chamber and the buffer-generating channel. The second ion exchange barrier can be disposed between the third chamber and the buffer-generating channel.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: February 28, 2017
    Assignees: Board of Regents, The University of Texas System, Dionex Corporation
    Inventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
  • Mixing device, mixing signal processing device, mixing program and mixing method
    Patent number: 9584906
    Abstract: A mixing device includes a signal data generation unit that generates signal data on a time-frequency plane composed of a time-axis and a frequency-axis from each of two or more input signals derived from a time domain, a signal processing unit that receives the signal data for the two or more input signals, and performs a mixing process that includes an adding operation of the signal data for each corresponding point on the time-frequency plane of the signal data for each of the input signals, and an output signal generation unit that receives the operation result of the signal processing unit and outputs an output signal formed by converting the inputted signal into a signal of a predetermined format.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: February 28, 2017
    Assignee: The University of Electro-Communications
    Inventors: Kota Takahashi, Wataru Owaki
  • Device and method for pressure-driven plug transport and reaction
    Patent number: 9579622
    Abstract: The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: February 28, 2017
    Assignee: The University of Chicago
    Inventors: Rustem F. Ismagilov, Joshua David Tice, Helen Song, Lewis Spencer Roach
  • Multiple-excitation multiple-receiving (MEMR) capacitance tomography
    Patent number: 9581560
    Abstract: A method for operating a sensor, including simultaneously exciting a first set of electrodes and sensing an output of each electrode of a second set of electrodes, storing output data corresponding to the output of each electrode of the second set of electrodes in a memory storage device, shifting at least one electrode from the first set of electrodes to the second set of electrodes and at least one electrode from the second set of electrodes to the first set of electrodes, and repeating the simultaneously exciting and sensing, the storing, and the shifting until an output data has been stored for each possible pair of electrodes in the first and second set of electrodes.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: February 28, 2017
    Assignees: The University of Conneticut, United Technologies Corporation
    Inventors: Zhaoyan Fan, Robert X. Gao, Jeffery A. Lovett, Lance L. Smith