Abstract: The invention provides a method for delivering cells across the surface of a tissue, the method comprising distributing the cells on and/or within a sheet of biomaterial to form a cell bandage and applying the cell bandage to the surface, wherein, after application of the cell bandage to the surface of the tissue, the cells are released from the cell bandage. Further provided is a method for bonding two or more tissues, the method comprising providing a cell bandage in intimate contact with the surfaces to be joined, wherein the cell bandage comprises a sheet of biomaterial, said biomaterial having cells distributed on and/or within it. Also provided is a cell bandage for use in the methods of the invention.

Abstract: The present invention provides compositions and methods for modulating G-alpha-q activity and methods of screening of test substances for the ability to modulate G-alpha-q activity.

Abstract: The present invention is directed to irciniastatin analogs. Uses of these analogs also described.

Abstract: The present invention relates, in general, to a prostate-specific antigen, PCA3. In particular, the present invention relates to nucleic acid molecules coding for the PCA3 protein; purified PCA3 proteins and polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to PCA3 proteins and polypeptides; hybridomas containing the antibodies; nucleic acid probes for the detection of nucleic acids encoding PCA3 proteins; a method of detecting nucleic acids encoding PCA3 proteins or polypeptides in a sample; kits containing nucleic acid probes or antibodies; bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess, or prognose a mammal afflicted with prostate cancer; therapeutic uses; and methods of preventing prostate cancer in an animal.

Abstract: Described herein is a method and system for characterizing in-ground rock types from measurement-while-drilling data in a mining environment. The method includes the steps of drilling holes at a plurality of selected locations within a region of interest; collecting measurements while drilling to obtain an array of data samples (162) indicative of rock hardness at various drilling depths in the drill hole locations; obtaining a characteristic measure (163) of the array of data samples; performing Gaussian Process regression (164) on the characteristic measure; and applying boundary detection (166) to the rock hardness output data obtained from the Gaussian process model to identify the distribution (280) of at least one cluster of rock type within the region of interest.

Abstract: Embodiments of an informatics platform where collected data can be normalized, integrated and mapped to a knowledge source, such as medical vocabulary systems are disclosed. One example of such a knowledge source is Unified Medical Language System (UMLS) which is a knowledge source for biomedical applications. Embodiments as depicted herein may provided a method to convert the desired information from UMLS into an ontology representation to allow for its use in conjunction with an informatics system.

Abstract: The present invention relates to a method of designing or optimizing a control surface for use with plasma actuators for controlling an aircraft, missile, munition or automobile, and more particularly to controlling fluid flow across their surfaces or other surfaces using plasma actuators, which would benefit from such a method. The various embodiments provide the steps to increase the efficiency of aircraft, missiles, munitions and automobiles. The method of flow control also provides a means for reducing aircraft, missile's, munition's and automobile's power requirements. These methods also provide alternate means for aerodynamic control using low-power hingeless plasma actuator devices.

Abstract: The present invention relates to a converter for transferring power between a first DC system of DC voltage V1 and a second DC system of DC voltage V2, the converter comprising: —a first AC/DC converter for transforming DC voltage V1 into a first single phase AC voltage V1ac, of frequency ?, root mean square line-neutral magnitude V1acm and angle ?1; a second AC/DC converter for transforming DC voltage V2 into a second single phase AC voltage V2ac, of frequency ?, root mean square line-neutral magnitude V2acm and angle ?2; and two inductors L1, L2 and a capacitor C, wherein the first terminals of the inductors and capacitor are connected together, the second terminal of inductor L1 and the second terminal of the capacitor C are connected to the first AC voltage V1ac, and the second terminal of inductor L2 and the second terminal of the capacitor C are connected to the second AC voltage V2ac; wherein the value of the capacitor C, inductor L1 and inductor L2 are selected to enable required power transfer and to

Abstract: Various methods and systems are provided for estimating and compensating for table deflection in reconstructed images. In one embodiment, a method for computed tomography (CT) imaging comprises reconstructing images from data acquired during a helical CT scan where table deflection parameters are estimated and the reconstruction is adjusted based on the table deflection parameters. In this way, images may be reconstructed without artifacts caused by table deflection.

Abstract: Embodiments may pertain to methods for preparing a transition metal oxide.

Abstract: A technique is presented for controlling behavior tracking by mobile apps executing on a mobile computing device. A set of profiles are managed by a privacy manager, where each profile represents a different isolated execution environment on the mobile computing device and defines a set of privacy rules governing an application while executing in an associated execution environment. Prior to launching the app, a user of the app is prompted by the privacy manager to select a profile for the app from the set of profiles. The privacy manager in turn applies the set of privacy rules associated with the selected profile to the app during execution of the app on the mobile computing device.

Abstract: The present invention intends to provide an assay system using split luciferase that has a remarkably high detection sensitivity. In an embodiment, binding of mutually binding first and second proteins is detected by preparing a first fusion protein comprising the first protein fused with a peptide having the amino acid sequence of amino acid SEQ ID NO: 1 and a second fusion protein comprising the second protein fused with a peptide having an amino acid sequence selected from the group consisting of amino acid SEQ ID NOS: 2 to 6, and allowing the first fusion protein to bind with the second fusion protein to form a complex, and detecting luminescence emitted from the complex.

Abstract: Apparatus and methods for size-specific detection of particles entrained in fluids are provided. A particle size selector separates particles entrained in a sample fluid stream using a curved channel. Shroud fluid streams are interposed between the sample fluid stream and walls of the channel. Centrifugal forces arising from fluid flow through the curved channel separate differently-sized particles into different transverse sections of the channel. A detector downstream from the particle size selector specifically detects particles in one or more transverse sections of the channel.

Abstract: The present invention relates generally to a flux focusing magnetic gear assembly using ferrite magnets or the like. The present invention also relates generally to a flux focusing magnetic gear assembly using ferrite magnets or the like that incorporates an outer stator assembly that converts a variable input to a constant output. The present invention further relates generally to an axially aligned flux focusing magnetic gear assembly using ferrite magnets or the like. The improved flux focusing magnetic gear assemblies of the present invention find applicability in traction, wind, and ocean power generation, among other applications.

Abstract: A process of producing a yarn, ribbon or sheet comprising nanofibers that includes infiltrating a liquid into the yarn, ribbon or sheet and evaporating the liquid from the yarn, ribbon, or sheet to strengthen the yarn, ribbon or sheet. The yarn, ribbon, or sheet can be formed by solid-state draw from a carbon nanotube forest.

Abstract: A position guidance system for minimally invasive medical procedures includes a medical device having a first end configured for percutaneous insertion and a second end configured to remain exterior to a patient's skin, a hub connection provided at the second end of the medical device, at least one bubble level including a bubble configured to provide a visual indication of a deviation from a target angle for medical device insertion, and a connector configured to reversibly and repeatedly connect the bubble level to the hub connection of the medical device. When the bubble is positioned at a center of the bubble level, an actual insertion angle of the medical device is the same as the target angle. When the bubble is positioned off-center of the bubble level, the actual insertion angle of the medical device deviates from the target angle.

Abstract: Combustion engine linkage mechanisms providing a longer piston stroke enabling high compression ratios without compromising the size or weight of the engine. The mechanisms accommodate different engine compression and expansion ratios to optimize thermodynamic efficiency for different loading conditions on demand.

Abstract: Methods and apparatus for moving and concentrating particles by applying an alternating driving field and an alternating field that alters mobility of the particles. The driving field and mobility-varying field are correlated with one another. The methods and apparatus may be used to concentrate DNA or RNA in a medium, for example. Methods and apparatus for extracting particles from one medium into another involve applying an alternating driving field that causes net drift of the particles from the first medium into the second medium but no net drift of the particles in the second medium.

Abstract: This invention relates to methods for altering cell proliferation in a plant by modulating the expression of an endogenous plant gene whose expression product affects cell proliferation. These methods can be used to modify plant characteristics, such as seed size. In particular, the invention provides methods for modifying cell proliferation in the integuments and/or seed coats of a plant by inhibiting expression of endogenous gene encoding Auxin response factor 2 (ARF2/MNT) or an orthologue thereof, such that the number of cells in the integuments and/or seed coat is increased, resulting in increased seed size. The plant or plant propagating material can be transformed, e.g., with a nucleic acid construct, to increase or decrease the expression of endogenous genes or the orthologues thereof that affect cell proliferation. The invention also relates to modified plants and reproducible plant material produced by the methods, and nucleic acid constructs for use in such methods.

Abstract: The present invention provides polypeptides with histone H3 lysine 79 methyltransferase activity as well as nucleic acids encoding the same. Also provided are methods of using the polypeptides and nucleic acids of the invention in screening assays to identify compounds of interest. Further provided are diagnostic methods for leukemia and prognostic methods to predict the course of the disease in a subject.