Abstract: In an aspect, a method of making a composite core-shell nanoparticle comprises forming a nanoparticle core comprising nickel oxide or iron oxide via thermal decomposition of a nickel complex or an iron complex; and forming an oxide shell over the core, the oxide shell comprising nickel, iron or a mixture thereof. In another aspect, a method of making composite nanoparticles comprises providing a mixture comprising nickel complex and iron complex; and thermally decomposing the nickel and iron complexes to provide the composite nanoparticles comprising (Ni,Fe)Ox alloy. In yet another aspect, a composition comprises composite nanoparticles, the composite nanoparticles including a nickel oxide core and oxide shell, the oxide shell comprising a mixture of nickel and iron.

Abstract: Methods for treating ovarian cancer comprising: administering to a patient and effective amount of a cannabis extract comprising CBD, wherein preferably, the cannabis extract is administered via a mucosal formulation.

Abstract: Described herein is an arm supporting exoskeleton, comprising an arm link mechanism. The arm link mechanism comprises a proximal link, a distal link, an arm coupler, and a variable force generator. The distal link is rotatable relative to the proximal link. The arm coupler is adapted to couple an upper arm of a person to the distal link. The variable force generator comprises a first spring and a second spring, configured to create a torque between the proximal link and the distal link. In the first force mode, the variable force generator exhibits a first stiffness rate defined by the first spring that supports the upper arm of the person against gravity forces and. In the second force mode, the variable force generator exhibits a second stiffness rate defined by the first spring and the second spring that supports the upper arm of the person against the gravity forces.

Abstract: A resonator comprising a magnetoelastic body having a mass load portion and an active resonating portion can be used in implementations such as a security tag. The resonator includes a mass at the mass load portion of the magnetoelastic body. Displacement of the magnetoelastic body is configured to occur at both the mass load portion and the active resonating portion. A strain at the active resonating portion during displacement is configured to be greater than a strain at the mass load portion during displacement.

Abstract: Precise polarimetric imaging of polarization-sensitive nanoparticles is essential to resolving their accurate spatial positions beyond the diffraction limit. However, conventional technologies typically employ mechanically rotated optical components, causing beam deviation errors that cannot be corrected beyond the diffraction limit. To overcome this limitation, a spatially stable nano-imaging system is presented for polarization-sensitive nanoparticles. In this disclosure, it is demonstrated that by integrating a voltage-tunable polarizer into optical microscopy, one is able to achieve high precision nano-imaging without mechanically induced image shift. It is also demonstrated that by integrating a voltage-tunable polarizer into photographic imaging system, one can achieve high-speed suppression of reflection glare and/or high-speed variation light exposure to the imager.

Abstract: A microscopy device comprises a continuous or pulsed wave laser light source; a pair of parallel mirrors configured to receive light from the light source and reflect an array of incoherent light sheets; a beam encoder (e.g., frequency modulation reticle, Hadamard basis, random modulation pattern) to segment the array of incoherent light sheets and encode each light sheet with a respective frequency in reciprocal space; a lens configured to direct the encoded light sheets towards a biological sample; and an image capturing device configured to receive a fluorescence signal from the biological sample.

Abstract: A sample carrier may include a sample preparation module and an amplification module. A sample mixes with a lysis medium and a nucleic acid amplification medium in the sample preparation module and then flows into a plurality of microfluidic chambers in the amplification module. The microfluidic chambers have disposed therein primers configured to initiate amplification of one or more target nucleic acid sequences corresponding to one or more pathogens. The sample carrier is inserted into an apparatus that includes a plurality of Sight sources and a camera. The light sources illuminate the microfluidic chambers with excitation light, a fluorophore emits fluorescence light indicative of nucleic acid amplification in response to the excitation-light, and the camera captures images of the microfluidic chambers. A target nucleic acid sequence in the sample is indicated by the images showing an increasing fluorescence in a microfluidic chamber that has the primers for that sequence.

Abstract: The present disclosure provides methods for identifying compounds that cause structural changes in a protein bound to an actin filament. The methods include the use of cells that include two actin-binding proteins, each labeled with a chromophore, and exposing the cells to a test compound. The method further includes detecting a change in fluorescence resonance energy transfer (FRET) between the chromophores.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: To provide novel compounds that are promising as prodrug-type anticancer agents, a compound represented by general formula (I) or a salt thereof is provided.

Abstract: The present disclosure presents aerial communication systems and methods. One such system comprises an unmanned aerial vehicle platform and a communication component integrated with the unmanned aerial vehicle platform, wherein the communication component is configured to establish an Air to Air (A2A) communication channel with a remote directional antenna that is integrated with a remote unmanned aerial vehicle platform. The system further includes a computing component integrated with the unmanned aerial vehicle platform, wherein the computing component is configured to determine an optimal heading angle for transmission of communication signals from a directional antenna to the remote directional antenna in an unknown communication environment from received signal strength indicator (RSSI) information obtained from the remote directional antenna. Other systems and methods are also disclosed.

Abstract: A fuel cell is an ammonia fuel cell using an ammonia-containing fuel. A catalyst used for an anode of the fuel cell is a ruthenium complex having two first ligands and one second ligand, and the first ligand is pyridine or a condensed cyclic pyridine compound with or without a substituent, and the second ligand is 2,2?-bipyridyl-6,6?-dicarboxylic acid with or without a substituent on a pyridine ring.

Abstract: The present invention includes a method of preparing differentiated endodermal cells comprising growing human pluripotent stem cells (hPSC) under serum free conditions for 3 days on a layer of fibronectin or a gelatinous protein layer in the presence of high activin/TGF-? with a GSK3 inhibitor and a PI3K/mTORC inhibitor in a basal differentiation medium; adding a knock out serum replacement to the media starting on day 4 through day 7; and harvesting the endodermal cells grown therein.

Abstract: A rice cultivar designated UADA1701081 is disclosed herein. The present invention provides seeds, plants, and plant parts derived from rice cultivar UADA1701081. Further, it provides methods for producing a rice plant by crossing UADA1701081 with itself or another rice variety. The invention also encompasses any rice seeds, plants, and plant parts produced by the methods disclosed herein, including those in which additional traits have been transferred into UADA1701081 through the introduction of a transgene or by breeding UADA1701081 with another rice cultivar.

Abstract: There are provided, inter alia, compositions and methods for treatment of cancer. The methods include administering to a subject in need a therapeutically effective amount of a Bruton's tyrosine kinase (BTK) antagonist and a ROR-1 antagonist. Further provided are pharmaceutical compositions including a BTK antagonist, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the BTK antagonist is ibrutinib and the ROR-1 antagonist is cirmtuzumab.

Abstract: A method for treating a noncancerous gynecological disorder comprising: administering to a patient and effective amount of composition comprising a cannabis extract comprising cannabidiol (CBD), wherein the composition is preferably administered in a mucosal form, such as intravaginally.

Abstract: A safety management system to prevent unauthorized use, accident, resale, theft, and so forth of a flying object. The safety management system includes changing, at a motor controller, a power feeding amount to each drive unit based on an instruction from a main control unit, an authentication information storage unit which records registered identification information for performing operator authentication, an authentication accepting unit which accepts an input of input identification information, an operator authentication unit which performs operator authentication of an operator of the flying object based on the input identification information and the registered identification information, and a safety managing unit connected between a power source of the flying object and the motor controller of the flying object. The safety managing unit includes a switch which controls electrical connection between the motor controller and the power source based on the result of the operator authentication.

Abstract: Antibodies and antigen-binding fragments thereof that specifically bind to human DCLK1 protein, hybridomas or other cell lines which express such antibodies and antigen-binding fragments thereof, nucleic acids, vectors, and host cells comprising nucleic acids which encode such antibodies and antigen-binding fragments thereof, and methods of use thereof are disclosed. In at least certain non-limiting embodiments, the antibodies or antigen-binding fragments thereof specifically bind to an epitope within isoform 2 or 4 of DCLK1 protein.

Abstract: A multimodal system for breast imaging includes an x-ray source, and an x-ray detector configured to detect x-rays from the x-ray source after passing through a breast. The system includes an x-ray detector translation system operatively connected to the x-ray detector so as to be able to translate the x-ray detector from a first displacement from the breast to a second displacement at least one of immediately adjacent to or in contact with the breast. The system includes an x-ray image processor configured to: receive a CT data set from the x-ray detector, the CT data set being detected by the x-ray detector at the first displacement; compute a CT image of the breast; receive a mammography data set from the x-ray detector, the mammography data set being detected by the x-ray detector at the second displacement; and compute a mammography image of the breast.

Abstract: Patterned polarizers with reduced transition regions are formed using a directional etch. Multiple layers can be combined to produce filters for polarization cameras and displays as well as achromatic filters.