Patents Assigned to The University
  • DISSOLUTION GUIDED WETTING OF STRUCTURED SURFACES
    Publication number: 20150210972
    Abstract: A microfabricated device having at least one gas-entrapping feature formed therein in a configuration that entraps air bubbles upon wetting the feature with a solvent or solution is described. The device includes a sacrificial residue in contact with the gas-entrapping feature, the dissolution of which guides the wetting of the gas-entrapping feature.
    Type: Application
    Filed: May 31, 2013
    Publication date: July 30, 2015
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Nancy Allbritton, Yuli Wang, Christopher Sims
  • DEVICE MEMBER INICLUDING CAVITY AND METHOD OF PRODUCING THE DEVICE MEMBER INCLUDING CAVITY
    Publication number: 20150211949
    Abstract: [Problem] The enclosing layer is not invaded in the gap, and the gap might not be buried, and the cavity which has the predetermined shape to be aimed can be formed by an easy step. [Resolution Approach] In the invention, comprising; the base member including the semiconductor 12, the interlayer 14, which is formed on the base member 12 and has the nonconductivity, the upper layer 16, which is formed on the interlayer 14 and includes the semiconductor, the opening portion 18 formed to the upper layer 16, the gas-permeable sealing layer 20, which is formed to seal the opening portion 18, wherein the cavity 22 is a cavity which is formed by removing the interlayer 14 with an etching gas that is penetrated through the sealing layer 20.
    Type: Application
    Filed: June 18, 2013
    Publication date: July 30, 2015
    Applicants: The University of Tokyo, Kabushiki Kaisha Saginomiya Seisakusho
    Inventors: Hiroyuki Fujita, Hiroshi Toshiyoshi, Hiroyuki Mitsuya
  • Antimalarial drug which contains 5-aminolevulinic acid or derivative thereof as active ingredient
    Patent number: 9089530
    Abstract: Provided is an antimalarial drug which is useful for prevention and treatment of infectious diseases caused by malaria parasites. A preventive and/or therapeutic agent for malaria, which contains, as an active ingredient, 5-aminolevulinic acid (ALA), a derivative thereof, or a pharmacologically acceptable salt thereof, is used.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: July 28, 2015
    Assignees: SBI Pharmaceuticals Co., Ltd., The University of Tokyo
    Inventors: Tohru Tanaka, Satofumi Kawata, Takeo Kohda, Motowo Nakajima, Kiyoshi Kita
  • Co-incubating confined microbial communities
    Patent number: 9090885
    Abstract: This invention provides devices and methods that enable co-incubation of microorganisms. Also provided are methods of making such devices for co-incubation of microorganisms, and various applications of such devices.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: July 28, 2015
    Assignee: The University of Chicago
    Inventors: James Q. Boedicker, Rustem F. Ismagilov, Hyun Jung Kim
  • Method and system for sharing router resources via a mobile virtual router
    Patent number: 9094342
    Abstract: An approach is provided for creating a single mobile virtual router (MVR) to share pooled resources. A mobile virtual router is formed to utilize resources of multiple routers of a network, wherein the routers include one or more physical routers, one or more virtual routers, one or more other mobile virtual routers, or a combination thereof. The resources of the single mobile virtual router are dynamically partitioned in response to an operational criterion of the network.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: July 28, 2015
    Assignees: Verizon Patent and Licensing Inc., Board of Regents, The University of Texas System, University of Houston System
    Inventors: Ning So, Andrea Fumagalli, Yuhua Chen
  • Acoustic source separation
    Patent number: 9093078
    Abstract: A method of separating a mixture of acoustic signals from a plurality of sources comprises: providing pressure signals indicative of time-varying acoustic pressure in the mixture; defining a series of time windows; and for each time window: a) providing from the pressure signals a series of sample values of measured directional pressure gradient; b) identifying different frequency components of the pressure signals c) for each frequency component defining an associated direction; and d) from the frequency components and their associated directions generating a separated signal for one of the sources.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: July 28, 2015
    Assignee: The University of Surrey
    Inventors: Banu Gunel Hacihabiboglu, Huseyin Hacihabiboglu, Ahmet Kondoz
  • Class of near infrared optical probes for biological applications
    Patent number: 9090602
    Abstract: 2,5-Bis(benzoxazol-2?-yl)benzene-1,4-diol derivatives (Zinhbo derivatives) are used to detect zinc ions and have particular application in vivo and in vitro. Zinhbo derivatives upon excitation give a florescence response emission that can be used to determine the presence of zinc cation in solution. Zinhbo derivatives complexed with zinc cations upon excitation can produce a florescence response emission in the visible and near infrared range. Zinhbo derivatives complexed with zinc cations exhibit a large stoke shift between the excitation and emission wavelengths.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: July 28, 2015
    Assignee: The University of Akron
    Inventors: Yi Pang, Yongqian Xu
  • Rapid isolation of monoclonal antibodies from animals
    Patent number: 9090674
    Abstract: Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: July 28, 2015
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Sai Reddy, Xin Ge, Jason Lavinder, Daniel Boutz, Andrew D. Ellington, Edward M. Marcotte, George Georgiou
  • Modified peptide substrate
    Patent number: 9091700
    Abstract: The invention provides novel reagents and methodologies for detecting free versus bound enzyme. It is particularly useful to detect thrombin when it is not bound to A2M in the presence of thrombin bound to A2M by using a modified substrate that is sterically hindered from reacting with the bound thrombin.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: July 28, 2015
    Assignees: McMaster University, The University of Melbourne
    Inventors: Leslie R. Berry, Vera Ignjatovic, Paul T. Monagle, Anthony K. Chan
  • Tumor specific antibodies and uses therefor
    Patent number: 9090698
    Abstract: Provided are isolated antibodies, and fragments and derivatives thereof, which bind to tumor antigens. Also provided are compositions and delivery agents that include the disclosed antibodies and fragments and derivatives thereof; cells that produce the same; methods for producing the same; methods of using the same for detecting, targeting, and/or treating tumors and/or metastatic cells derived therefrom and/or tumor stem cells; and methods for predicting the recurrence of cancer in a subject.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: July 28, 2015
    Assignee: The University of North Carolina at Charlotte
    Inventor: Pinku Mukherjee
  • Bis-(8-quinolinolato-N,O)platinum(II) based organic photovoltaic cell
    Patent number: 9093654
    Abstract: Organic photovoltaic (OPV) cells and methods of forming the same are provided. An OPV cell can include an organic photoactive layer comprising bis-(8-quinolinolato-N,O)platinum (II) (PtQ2) having a general structure disclosed herein as Structure I. A method of forming an OPV cell can include forming an organic photoactive layer on a substrate, which can include a transparent electrode. The organic photoactive layer can comprises PtQ2 having the general structure of Structure I.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: July 28, 2015
    Assignee: The University of Hong Kong
    Inventors: Chi Ming Che, Hai Feng Xiang
  • Method of transfection and compositions therefor
    Patent number: 9089508
    Abstract: The present invention relates to the targeted delivery of molecules to cells expressing toll-like receptors (TLRs). Aspects of the invention provide compounds comprising a positively charged group linked to a TLR ligand. These compounds are useful for in vitro and in vivo methods of transfection of TLR-expressing cells. Other aspects of the invention relate to the use of such compounds for repression of gene expression and DNA vaccination approaches.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: July 28, 2015
    Assignee: The University of Melbourne
    Inventors: David Charles Jackson, Weiguang Zeng, Brendon Yew Loong Chua
  • Method of preventing or treating influenza A viral infection using cloned DI influenza A viral particles
    Patent number: 9089516
    Abstract: Cloned, i.e. defined, defective interfering (DI) influenza A virus is produced in embryonated hens eggs using a method which generates large quantities of DI virus material. Co-administration of cloned DI influenza A virus with a lethal dose of virulent influenza A virus conferred protection in mice compared to a control of inactivated cloned DI influenza A virus. Control mice which received only cloned DI influenza A virus and no lethal challenge of virulent influenza A virus were not protected three weeks later on lethal challenge with infective virus. Cloned DI influenza A virus of one subtype is found to act in vivo as an effective antiviral against the same or any other sub-type of influenza A virus. The antiviral effect has been found to have both a therapeutic and a prophylactic application against influenza A infection in humans, mammals and birds.
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: July 28, 2015
    Assignee: The University of Warwick
    Inventor: Nigel Dimmock
  • SUPERVISED MACHINE LEARNING TECHNIQUE FOR REDUCTION OF RADIATION DOSE IN COMPUTED TOMOGRAPHY IMAGING
    Publication number: 20150201895
    Abstract: Substantial reduction of the radiation dose in computed tomography (CT) imaging is shown using a machine-learning dose-reduction technique. Techniques are provided that (1) enhance low-radiation dosage images, beyond just reducing noise, and (2) may be combined with other approaches, such as adaptive exposure techniques and iterative reconstruction, for radiation dose reduction.
    Type: Application
    Filed: August 30, 2013
    Publication date: July 23, 2015
    Applicant: The University of Chicago
    Inventor: Kenji Suzuki
  • LEVEL CONVERSION CIRCUIT
    Publication number: 20150207508
    Abstract: A level conversion circuit has a keeper circuit for retaining an intermediate output node at a high output level to avoid it floating due to leakage through a pullup transistor in a shifting circuit. Thin oxide and thick oxide versions of the level conversion circuit can be provided. The level conversion circuit enables higher performance, reduced power consumption and reduced susceptibility to process variation compared to previous level conversion designs.
    Type: Application
    Filed: January 22, 2014
    Publication date: July 23, 2015
    Applicant: The Regents of The University of Michigan
    Inventors: Allan Ailun WANG, David Theodore Blaauw, Dennis Michael Sylvester
  • Orvinol and Thevinol Derivatives Useful in the Treatment of Drug and Alcohol Abuse
    Publication number: 20150202200
    Abstract: The invention provides orvinol and thevinol compounds useful for the treatment of drug and alcohol abuse, the compounds being particularly useful for the prevention of relapse in recovering addicts.
    Type: Application
    Filed: March 31, 2015
    Publication date: July 23, 2015
    Applicant: The University of Bath
    Inventors: John LEWIS, Stephen Husbands
  • Compositions and methods for controlling proliferation and differentiation of cells
    Patent number: 9084752
    Abstract: Methods and compositions for modulating cell differentiation, proliferation and morphology in vitro or in vivo are described. The methods include modifying the extracellular nanoenvironment of stem cells with a self-assembling peptide nanofiber scaffold. The extracellular nanoenvironment can be modified by changing the percentage of self-assembling peptides used to form the nanofiber scaffold, the concentration of cells in the nanofiber scaffold, the pH, or the amounts of serum. Modulating the extracellular nanoenvironment of cells in nanofiber scaffold allows for increased targeting of cell placement and therapeutic delivery, amplified by cell encapsulation and implantation.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: July 21, 2015
    Assignee: The University of Hong Kong
    Inventors: Rutledge Ellis-Behnke, David Kiong-Chiu Tay
  • Semiconductor devices with 2DEG and 2DHG
    Patent number: 9087889
    Abstract: A semiconductor device comprises three semiconductor layers. The semiconductor layers are arranged to form a 2DHG and a 2DEG separated by a polarization layer. The device comprises a plurality of electrodes: first and second electrodes electrically connected to the 2DHG so that current can flow between them via the 2DHG and a third electrode electrically connected to the 2DEG so that when a positive voltage is applied to the third electrode, with respect to at least one of the other electrodes, the 2DEG and the 2DHG will be at least partially depleted.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: July 21, 2015
    Assignee: The University of Sheffield
    Inventors: Akira Nakajima, Sankara Narayanan Ekkanath Madathil
  • Methods and apparatus for image processing in wireless capsule endoscopy
    Patent number: 9088716
    Abstract: Methods and apparatus for image processing suitable for use in wireless capsule endoscopy are provided. The image processing techniques exploit characteristic features of endoscopic images to enable low complexity compression. A color space conversion, coupled with lossless predictive coding and variable length coding are employed. Sub-sampling and clipping may also be used. The described image processing can be used both with both white-band imaging and narrow-band-imaging.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: July 21, 2015
    Assignee: The University of Saskatchewan
    Inventors: Tareq Hasan Khan, Khan Arif Wahid
  • Preparation of metal colloids
    Patent number: 9086381
    Abstract: A method for producing a silver colloid solution of highly stable resulting colloids includes adding an aqueous solution of a hydroxylamine salt to an aqueous solution of an alkali, and then dispersing into the mixture an aqueous solution of the metal ions, the hydroxylamine salt being selected such that the anion, when combined with the said metal ions, would form a metal salt having a very low solubility in water, wherein the metal ion solution is introduced into the mixture in such a manner that the metal ions are substantially dispersed throughout the mixture within one second. A maturing period, preferably at elevated temperatures, leads to a stable state.
    Type: Grant
    Filed: September 28, 2013
    Date of Patent: July 21, 2015
    Assignee: The University of Lincoln
    Inventors: Peter Cyril White, Jakob Howie Hjortkjaer