Abstract: A vapour of a blend comprising the oil of orange and the oil of bergamot, a process for its preparation and its use as an antimicrobial. The vapour has been found to be particularly useful on food contaminated with microorganisms without affecting the sensory properties of the food.
Abstract: The present invention relates to cGMP protein kinase (PKG) and regulatory domains and methods of use thereof. The structural determination of PKG domains is also described. cGMP independent PKG activators and uses thereof are also described.
Type:
Application
Filed:
March 13, 2013
Publication date:
February 6, 2014
Applicant:
The University of Vermont and State Agricultural College
Inventors:
Wolfgang Dostmann, Brent W. Osborne, Thomas M. Moon
Abstract: A method for producing light emission from a two terminal semiconductor device with improved efficiency, includes the following steps: providing a layered semiconductor structure including a semiconductor drain region comprising at least one drain layer, a semiconductor base region disposed on the drain region and including at least one base layer, and a semiconductor emitter region disposed on a portion of the base region and comprising an emitter mesa that includes at least one emitter layer; providing, in the base region, at least one region exhibiting quantum size effects; providing a base/drain electrode having a first portion on an exposed surface of the base region and a further portion coupled with the drain region, and providing an emitter electrode on the surface of the emitter region; applying signals with respect to the base/drain and emitter electrodes to obtain light emission from the base region; and configuring the base/drain and emitter electrodes for substantial uniformity of voltage distrib
Type:
Application
Filed:
July 23, 2013
Publication date:
February 6, 2014
Applicants:
The Board of Trustees of The University of Illinois
Inventors:
Gabriel Walter, Nick Holonyak, Milton Feng, Chao-Hsin Wu
Abstract: The present disclosure is directed to compositions and methods for formulating a pharmaceutical dosage form by forming a composition comprising acetyl-11-keto-?-boswellic acid, diindolylmethane, or curcumin with one or more pharmaceutically acceptable excipients for enhanced solubility to increase bioavailability and improve therapeutic efficacy. The composition can be processed by thermo-kinetic compounding along with conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
Type:
Application
Filed:
February 23, 2012
Publication date:
February 6, 2014
Applicants:
Dispersol Technologies. LLC, Board of Regents, The University of Texas System
Inventors:
Chris Brough, Robert O. Williams, III, James W. McGinity, Dave A. Miller, Justin Hughey, Ryan Bennett
Abstract: The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.
Type:
Application
Filed:
September 8, 2011
Publication date:
February 6, 2014
Applicants:
The University of Queensland, Howard Florey Institute of Experimental Physiology and Medicine
Inventors:
Karl Johan Rosengren, Linda Maria Haugaard-Kedstrom, Ross Alexander David Bathgate, Mohammed Akhter Hossain, John Desmond Wade, Andrew Lawrence Gundlach, Andrew J. Lawrence
Abstract: A method for producing light emission from a two terminal semiconductor device with improved efficiency, includes the following steps: providing a layered semiconductor structure including a semiconductor drain region comprising at least one drain layer, a semiconductor base region disposed on the drain region and including at least one base layer, and a semiconductor emitter region disposed on a portion of the base region and comprising an emitter mesa that includes at least one emitter layer; providing, in the base region, at least one region exhibiting quantum size effects; providing a base/drain electrode having a first portion on an exposed surface of the base region and a further portion coupled with the drain region, and providing an emitter electrode on the surface of the emitter region; applying signals with respect to the base/drain and emitter electrodes to obtain light emission from the base region; and configuring the base/drain and emitter electrodes for substantial uniformity of voltage distrib
Type:
Application
Filed:
July 22, 2013
Publication date:
February 6, 2014
Applicants:
The Board of Trustees of The University Of IIIinois, Quantum Electro Opto Systems Sdn. Bhd.
Inventors:
Gabriel Walter, Nick Holonyak, JR., Milton Feng, Chao-Hsin Wu
Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer, ovarian cancer of low malignant potential, benign ovarian disease or other malignant condition. The biomarkers can be detected by SELDI mass spectrometry.
Type:
Application
Filed:
June 12, 2013
Publication date:
February 6, 2014
Applicants:
The University of Kentucky Research Foundation, Vermillion, Inc.
Inventors:
Eric Thomas Fung, Frederick Rand Ueland, Van Nagell, JR., Paul Duane Depriest, Andre Thomas Baron
Abstract: A method for fingerprinting a video involving identifying motion within the video and using a measure of the identified motion as a fingerprint. Once videos are fingerprinted, these fingerprints can be used in a method for identifying video. This involves creating a motion fingerprint for unidentified videos; comparing the fingerprints of the known and unknown videos, and identifying whether the unknown video is a copy of the known video based on the step of comparing.
Type:
Application
Filed:
October 15, 2013
Publication date:
February 6, 2014
Applicant:
The University Court of the University of St. Andrews
Abstract: Disclosed are electrochemical methods, apparatus, systems and kits for the detection or monitoring of proteolysis of proteinaceous matrices such as fibrin clots. The methods, apparatus, systems and kits generally include the use of voltammetric techniques to measure the changes in current that result from diffusion of an electroactive species towards an electrode on proteolysis of a proteinaceous matrix.
Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain (4-phenyl-piperidin-1-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds that, inter alia, inhibit 11?-hydroxysteroid dehydrogenase type 1 (11?-HSD1). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit 11?-hydroxysteroid dehydrogenase type 1; to treat disorders that are ameliorated by the inhibition of 11?-hydroxysteroid dehydrogenase type 1; to treat the metabolic syndrome, which includes disorders such as type 2 diabetes and obesity, and associated disorders including insulin resistance, hypertension, lipid disorders and cardiovascular disorders such as ischaemic (coronary) heart disease; to treat CNS disorders such as mild cognitive impairment and early dementia, including Alzheimer's disease; etc.
Type:
Grant
Filed:
September 14, 2010
Date of Patent:
February 4, 2014
Assignee:
The University Of Edinburgh
Inventors:
Scott Peter Webster, Jonathan Robert Seckl, Brian Robert Walker, Peter Ward, Thomas David Pallin, Hazel Joan Dyke, Trevor Robert Perrior
Abstract: This invention provides a family of functionalized polymers capable of forming membranes having exceptional OH? ionic conductivity as well as advantageous mechanical properties. The invention also provides membranes including the provided polymers and AEMFC/HEMFC fuel cells including such membranes. In a preferred embodiment, preferred function groups include a quaternary phosphonium, and in a more preferred embodiment the provided polymer is (tris(2,4,6-trimethoxyphenyl) phosphine)3 functionalized phosphonium polysulfone hydroxide.
Type:
Grant
Filed:
October 9, 2009
Date of Patent:
February 4, 2014
Assignee:
The Regents of The University of California
Abstract: This application describes methods and compositions for detecting and treating C6Orf150-associated neoplasia. Differential methylation of the C6Orf150 nucleotide sequences has been observed in C6Orf150-associated neoplasia such as colon neoplasia.
Type:
Grant
Filed:
August 27, 2010
Date of Patent:
February 4, 2014
Assignees:
Case Western Reserve University, Board of Regents, The University of Texas System
Inventors:
Sanford D. Markowitz, Helen Moinova, Lois Myeroff, Jean-Pierre Issa, Osamu Maeda
Abstract: An apparatus for retaining a photovoltaic panel on a rooftop includes a vessel having a first side, second side, front, bottom, and top panels, wherein the panels are attached to define a void within the vessel. A fill port is disposed on the vessel. A first hole is adapted to receive a screw on the top panel, wherein the first hole is aligned with a second hole disposed on the bottom panel, wherein the first and second holes are adapted to be aligned with a third hole on a first mounting cross arm. The top panel is inclined at an angle relative to the bottom panel.
Type:
Grant
Filed:
September 2, 2010
Date of Patent:
February 4, 2014
Assignees:
The University of Houston System, Metalab LLC, Standard Renewable Energy Inc.
Inventors:
Joseph Meppelink, Andrew Vrana, Chris Boyer
Abstract: A method for altering the lifespan of a eukaryotic organism. The method comprises the steps of providing a lifespan altering compound, and administering an effective amount of the compound to a eukaryotic organism, such that the lifespan of the organism is altered. In one embodiment, the compound is identified using the DeaD assay.
Abstract: The invention is directed to a method of preparing polymeric metallomacrocycles having measurable photo- and electroluminescence properties and devices using such materials. In an embodiment, an O-hexyl-3,5-bis(terpyridine)phenol ligand has been synthesized and transformed into a hexagonal Zn(II)-metallomacrocycle by a facile self-assembly procedure capitalizing on terpyridine-Zn(II)-terpyridine connectivity. The material is usable in an OLED device based on the photo- and electro-luminescence characteristics thereof.
Type:
Grant
Filed:
August 3, 2012
Date of Patent:
February 4, 2014
Assignee:
The University of Akron
Inventors:
George R. Newkome, Charles N. Moorefield
Abstract: The present invention relates to isolated Porphyromonas gingivalis polypeptides and nucleotides. The polypeptides include an amino acid sequence selected from the group consisting of: SEQ. ID. NO. 110; SEQ. ID. NO. 111; SEQ. ID. NO. 112; SEQ. ID. NO. 113; SEQ ID NO: 120; SEQ. ID. NO. 123; SEQ. ID. NO. 124; SEQ. ID. NO. 125; SEQ. ID. NO. 130; SEQ. ID. NO. 131; SEQ. ID. NO. 132; SEQ. ID. NO. 133; SEQ. ID. NO. 135; SEQ. ID. NO. 136; SEQ. ID. NO. 137; SEQ. ID. NO. 138; SEQ. ID. NO. 143; SEQ. ID. NO. 144; SEQ. ID. NO. 145; SEQ. ID. NO. 146; SEQ. ID. NO. 147; SEQ. ID. NO. 148; and amino acid sequences at least 95% identical thereto.
Type:
Grant
Filed:
February 21, 2012
Date of Patent:
February 4, 2014
Assignees:
CSL Limited, The University of Melbourne
Inventors:
Bruce C. Ross, Ian G. Barr, Michelle A. Patterson, Catherine T. Agius, Linda J. Rothel, Mai B. Margetts, Dianna M. Hocking, Elizabeth A. Webb
Abstract: The present disclosure relates to methods of inhibiting the ATPase activity of Na/K-ATPase without stimulating the receptor function, methods of blocking Na/K-ATPase interaction with Src, methods of inhibiting cell growth, and methods of abolishing ouabain-provoked signaling transduction in the heart of a subject, which includes providing an effective amount of at least one hydroxyl xanthone derivative.
Type:
Application
Filed:
October 3, 2013
Publication date:
January 30, 2014
Applicant:
The University of Toledo
Inventors:
Zi-Jian Xie, Joseph I. Shapiro, Shuyi Si, Zhongbing Zhang
Abstract: The present invention provides a pH sensing apparatus that includes a flexible polymer substrate, one or more amorphous iridium oxide film sensor electrodes disposed on the flexible polymer substrate, and a reference electrode corresponding to each amorphous iridium oxide film sensor electrode. Each reference electrode is disposed on the flexible polymer substrate in close proximity to the corresponding amorphous iridium oxide film sensor electrode. The amorphous iridium oxide film sensor electrodes provide a potential in reference to the reference electrodes that varies according to a pH of a substance contacting the amorphous iridium oxide film sensor electrodes and the reference electrodes.
Type:
Application
Filed:
September 26, 2013
Publication date:
January 30, 2014
Applicant:
Board of Regents, The University of Texas System
Abstract: Disclosed is a method of preparing terminally functionalized telechelic polymers using a cationic living polymer product or a terminal tert-chloride chain end of a carbocationic quasiliving polymer product, which comprises quenching the polymer product with a functionalized N-substituted pyrrole to thereby introduce the functionalized N-substituted pyrrole at the terminal reactive polymer chain end(s). A method is also disclosed whereby the N-substituent may be derivatized to a basic amine containing functional group. Also disclosed are the terminal functionalized polyisobuyl N-substituted pyrrole compounds where the polyisobutyl group is substituted at the 2 and 3 position of the N-substituted pyrrole.
Type:
Application
Filed:
September 27, 2013
Publication date:
January 30, 2014
Applicants:
The University of Southern Mississippi, Chevron Oronite Company LLC
Inventors:
Robson F. Storey, Casey D. Stokes, James J. Harrison, Nemesio Martinez-Castro