Abstract: The present invention belongs to the field of organophosphorus pesticide (OP) detection, and relates to a method for detecting an OP by a microfluidic chip based on a fluorescent sensing film. A porous fluorescent sensing film and the microfluidic chip are first constructed. The fluorescent sensing film is fabricated through layer-by-layer self-assembly of a platinum nanoparticle@oxalate-metal-organic framework (MOF) composite and a porous two-dimensional (2D) nanosheet, and has the functions of specifically detecting OPs and blocking macromolecular interferents. The microfluidic chip includes a sample channel, injection channels, reaction tanks, microfluidic channels, a detection tank, and an optical fiber channel, such that sample pretreatment and detection processes are integrated in the chip.
Abstract: Devices and systems for droplet generation and methods for generating droplets are described. In an embodiment, the devices and systems include a capillary configured to eject a droplet, such as in response to a voltage applied to an end of the capillary. In an embodiment, the devices and systems include a moveable stage configured to carry a multi-well plate and move the stage relative to the capillary such that the ejected droplet is selectively received by a well of the multi-well plate carried by the moveable stage.
Abstract: Ossicular prostheses, and methods for producing such, are disclosed for treatment of middle ear damage caused by a malady of the middle ear such as cholesteatoma. The ossicular prostheses comprises a strut component attached to a disc via a rigid or flexible connecting joint. The strut is attachable to a head or footplate of a subject's stapes. The disc is attachable to the subject's existing tympanic membrane, or, alternatively, to an artificial tympanic membrane graft. In some embodiments, a scaffold is used to support the ossicular prosthesis and the tympanic membrane graft.
Type:
Grant
Filed:
January 21, 2020
Date of Patent:
April 22, 2025
Assignee:
The Board of Regents of the University of Oklahoma
Inventors:
Rong Z. Gan, Betty Tsai Do, Marcus A. Brown
Abstract: A bismuth iodide oxide/zinc oxide composite material, a preparation method therefor and an application thereof in piezoelectric photocatalytic removal of organic pollutants. The conductive substrate spin-coated with a zinc oxide seed solution is annealed and added to the precursor solution for reaction to obtain a zinc oxide nanorod array (ZnO NRs); the zinc oxide nanorod array is added into a bismuth iodide precursor solution for reaction to obtain the bismuth iodide oxide/zinc oxide composite material (BiOI/ZnO NAs). The composite material is put into an aqueous solution containing bisphenol A, adsorption is performed in the dark for half an hour, and then ultrasound and visible light are used together to remove organic pollutants in the water. After piezoelectric photocatalytic degradation of 90 minutes, bisphenol A in the aqueous solution is almost completely degraded.
Abstract: This present disclosure provides devices, systems, and methods relating to the modulation of tissue temperature. In particular, the present disclosure provides devices, systems, and methods for rapidly cooling or heating tissue in a subject as a therapeutic and/or prophylactic means for treating tissue that has been injured or damaged.
Type:
Grant
Filed:
September 6, 2019
Date of Patent:
April 22, 2025
Assignee:
DUKE UNIVERSITY
Inventors:
Rafael Eduardo Chaparro, Paolo Maccarini, Luis Fernando Gonzalez, Donald Pearce, Edward Lysk Wyckoff, III, Syed Faaiz Enam, Jikai Shen, Aliesha O'Raw, Rachel Yang
Abstract: Disclosed are a tungsten hexafluoride preparation method and apparatus based on photoelectric synergy. A photocatalyst and metal tungsten are sequentially filled in a discharge area of a plasma reactor in a direction of gas entry, and the discharge area of the plasma reactor is irradiated with light at the same time; the background gas generates a large amount of plasma in the discharge area, SF6 undergoes decomposition under the synergistic effect of photocatalysis and plasma, SF6 is decomposed to generate fluorine atoms and low-fluorine sulfides such as SF5 and SF4. The generated fluorine ions, SF5, SF4 and low-fluorine sulfides further react with metal tungsten to generate WF6 specialty gas, which not only realizes the utilization of fluorine resources of SF6, but also replaces highly toxic fluorine gas with non-toxic SF6 exhaust gas in the plasma reactor for reaction, thereby ensuring safe operation and low energy consumption.
Type:
Grant
Filed:
October 30, 2024
Date of Patent:
April 22, 2025
Assignees:
Hubei University of Technology, Electric Power Research Institute China Southern Power Grid, Handan Puxin Electric Power Technology Co., Ltd.
Inventors:
Yalong Li, Xiaoxing Zhang, Mingli Fu, Zhaodi Yang, Lei Jia, Kun Wan, Dibo Wang, Guozhi Zhang, Shuangshuang Tian, Guoguang Zhang, Guangke Li
Abstract: A sensing circuit for detecting hardware trojans in a target integrated circuit is provided. The sensing circuit includes an array of magnetic tunnel junction circuits where each magnetic tunnel junction circuit including one or more magnetic tunnel junctions. Characteristically, each magnetic tunnel junction circuit configured to provide data for and/or determine a temperature map or a current map of the target integrated circuit.
Abstract: A drug for the prevention or treatment of sepsis is provided. The drug comprises an exosome containing a circRNA MOTOR, and a nucleotide sequence corresponding to the circRNA MOTOR is shown in SEQ ID NO: 1.
Type:
Grant
Filed:
November 21, 2024
Date of Patent:
April 22, 2025
Assignee:
SOUTHEAST UNIVERSITY
Inventors:
Wei Huang, Haibo Qiu, Ke Fang, Jianfeng Xie, Ling Liu, Yi Yang, Ran Yang
Abstract: This invention relates to antibacterial compounds and compositions thereof. The invention also relates to the use of the compounds and compositions in methods of treating bacterial infections, particularly those bacterial infections including bacteria that exhibit antibiotic resistance. More specifically, the present invention provides a star shaped peptide polymer comprising a multifunctional core with a plurality of terminal arms extending therefrom, wherein the terminal arms are statistical or random peptide copolymers of at least a cationic amino acid residue and a hydrophobic amino acid residue.
Type:
Grant
Filed:
November 2, 2017
Date of Patent:
April 22, 2025
Assignee:
The University of Melbourne
Inventors:
Greg GuangHua Qiao, Neil Martin O'Brien-Simpson, Shu Jie Lam, Anton Richard Blencowe, Eric Charles Reynolds
Abstract: The present invention includes scalable and cost-effective auxetic foam sensors (AFS) created through conformably coating a thin conductive nanomaterial-sensing layer on a porous substrate having a negative Poisson's ratio. In general, the auxetic foam sensors possess multimodal sensing capability, such as large deformation sensing, small pressure sensing, shear/torsion sensing and vibration sensing and excellent robustness in humidity environment.
Type:
Grant
Filed:
October 11, 2023
Date of Patent:
April 22, 2025
Assignee:
The Florida State University Research Foundation, Inc.
Inventors:
Changchun Zeng, Zhiyong Liang, Yan Li, Sida Luo, Tao Liu
Abstract: A method for foundation consolidation combining vacuum preloading and geomembrane bag assembly loading, which comprises: digging a slurry pit, filling mud into the slurry pit and conducting vacuum preloading pumpdrainage for multiple times, laying the geomembrane bag assemblies above the soft slurry seam processed through vacuum preloading pumpdrainage inside the slurry pit to form a plurality of loading layers, and laying the geomembrane bag assemblies by piling geomembrane bags. In view of the engineering complexity and uneven settlement resulting from conventional vacuum preloading using slag loading, geomembrane bag for loading to overcome the adverse effects of slag loading. In the present invention, the drainage system and the geomembrane bag assemblies are laid out to fully leverage their perspective properties, so as to improve the transmission of vacuity in the whole soil mass, speed up the drainage rate, and increase the degree of consolidation.
Type:
Grant
Filed:
April 21, 2022
Date of Patent:
April 22, 2025
Assignee:
Wenhou University
Inventors:
Yuanqiang Cai, Jun Wang, Hongtao Fu, Shihu Gao, Bin Yang, Xiaoxiao Zhu, Rila Anda, Guohui Yuan
Abstract: A motor having multiple cooling flow channels, includes a housing, a stator, and a rotor. The stator comprises a winding. The housing comprises a cooling liquid inlet, an arc-shaped flow channel, and a cooling liquid outlet; the arc-shaped flow channel is defined around the housing and connected to the stator core; the rotor comprises a rotor flow channel; both the rotor flow channel and the arc-shaped flow channel are communicated with the cooling liquid inlet and outlet; and the rotor flow channel and the arc-shaped flow channel respectively correspond to two ends of the winding. A cooling liquid enters the arc-shaped flow channel for cooling the housing and a stator core of the motor, and enters the rotor flow channel for cooling the rotor. The cooling liquid flows through the rotor flow channel and the arc-shaped flow channel for respectively cooling the ends of the winding.
Type:
Grant
Filed:
December 5, 2022
Date of Patent:
April 22, 2025
Assignees:
South China University of Technology, KINETEK DE SHENG (SHUNDE) MOTOR CO., LTD.
Abstract: The present invention relates to the technical field of maglev transportation, specifically revealing a method and apparatus for measuring magnetic field intensity in high-temperature superconducting maglev transportation systems.
Type:
Grant
Filed:
April 25, 2024
Date of Patent:
April 22, 2025
Assignee:
Southwest Jiaotong University
Inventors:
Rong Chen, Ping Wang, Tao Lv, Jingmang Xu, Zhou Xu, Kai Liu, Min Xue
Abstract: A method of diagnosing the likelihood of recurrence of clear cell renal cell carcinoma is provided. The method involves a) detecting the gene expression signatures of mitochondrial electron transport chain subunits, mitochondrial ribosomal proteins, major histocompatibility complex class II (MHC-II) proteins or combinations thereof in a kidney tumor tissue sample; and b) determining that the subject has an elevated risk of recurrence of clear cell renal cell carcinoma if the gene expression signatures include certain sequences. In another embodiment, the method uses copper levels to diagnose the likelihood of recurrence of clear cell renal cell carcinoma.
Type:
Grant
Filed:
May 21, 2021
Date of Patent:
April 22, 2025
Assignee:
University of Cincinnati
Inventors:
Maria Franciszka Czyzyk-Krzeska, Julio Alberto Landero Figueroa, Jarek Meller, David Plas, Shuchi Gulati, Bhargav Vemuri, John Thomas Cunningham, IV
Abstract: The present disclosure provides a stretchable and flexible sweat-activated graphene-coated Ni foam-based Mg—O2 battery capable of powering an intelligent and flexible electronics for health monitoring purposes with different biosensors.
Abstract: Provided is a resource monitoring apparatus including a log generation unit for extracting a method requested from a hardware abstraction layer and generating a log; a log classification unit for classifying the generated log according to a type of an interface connected to the method; and a log determination unit for identifying a malicious activity from the classified log based on pattern information of the log set differently depending on the type of the interface.
Type:
Grant
Filed:
November 26, 2020
Date of Patent:
April 22, 2025
Assignee:
FOUNDATION OF SOONGSIL UNIVERSITY-INDUSTRY COOPERATION
Abstract: A data processing method based on a memristor array and an electronic apparatus are disclosed. The data processing method based on a memristor array includes: acquiring a plurality of first analog signals; setting the memristor array, and writing data corresponding to a convolution parameter matrix of a convolution processing into the memristor array; inputting the plurality of first analog signals respectively into a plurality of column signal input terminals of the memristor array that has been set, controlling operation of the memristor array to perform the convolution processing on the plurality of first analog signals, and obtaining a plurality of second analog signals after performing the convolution processing at a plurality of row signal output terminals of the memristor array, respectively.
Type:
Grant
Filed:
December 14, 2021
Date of Patent:
April 22, 2025
Assignee:
TSINGHUA UNIVERSITY
Inventors:
Huaqiang Wu, Zhengwu Liu, Jianshi Tang, Bin Gao, He Qian
Abstract: The widespread utilization and growing demand for radiopharmaceuticals are attributable to the development and availability of a range of radiopharmaceuticals. The present disclosure describes methods of making 3-dimensional nano-porous, micro-porous, meso-porous, or macro-porous materials. The present disclosure also describes methods of irradiating and separating isotopes using the 3-dimensional nano-porous, micro-porous, meso-porous, or macro-porous materials.
Type:
Grant
Filed:
November 5, 2021
Date of Patent:
April 22, 2025
Assignees:
NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION, UNM RAINFOREST INNOVATIONS
Inventors:
Douglas Wells, Nikolai Kalugin, Alexey Serov
Abstract: A retinal projection display device is provided. The retinal projection display device includes a light source configured to emit light, a spatial light modulator configured to generate diffracted light by diffracting the emitted light, a holographic optical element configured to reflect the diffracted light by duplicating the diffracted light into a plurality of complex wavefronts, and a field lens configured to focus the plurality of complex wavefronts to a plurality of respective focal points in an eye-box, wherein the plurality of complex wavefronts overlap each other.
Type:
Grant
Filed:
March 3, 2023
Date of Patent:
April 22, 2025
Assignees:
SAMSUNG ELECTRONICS CO., LTD., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION