Abstract: An antenna assembly may include a shape change antenna configured to transmit an electromagnetic wave or receive an electromagnetic wave. The shape change antenna may have an antenna shape and may be formed of a conductive shape memory material that physically moves in response to changes in a non-geometric characteristic. The antenna assembly may also include a shape change stimulator configured to change the non-geometric characteristic of the shape change antenna to cause the antenna shape to physically change between a first geometry and a second geometry.

Abstract: The present invention provides a pharmaceutical composition comprising a compound exhibiting coronavirus proliferation inhibitory activity. A pharmaceutical composition comprising a compound represented by the formula: wherein Y is N; R1 is substituted or unsubstituted aromatic heterocyclyl; R2 is substituted or unsubstituted 6-membered aromatic carbocyclyl; R3 is substituted or unsubstituted aromatic heterocyclyl; —X— is —NH—; m is 0 or 1; R5a is a hydrogen atom; R5b is a hydrogen atom; n is 1; R4a is a hydrogen atom; and R4b is a hydrogen atom, or a pharmaceutically acceptable salt thereof.

Abstract: A waterborne autonomous rescue device floats in a body of water and continuously senses an ambient audio in the body of water, and performs voice recognition on the ambient audio to recognize a cry-out-for-help voice, and calculates a direction of an emission source (e.g. a drowning person) that emits the cry-out-for-help voice, and then the waterborne autonomous rescue device will automatically move forward in the direction of the emission source, so that the drowning person can cling to the waterborne autonomous rescue device and be carried to a safe location; a waterborne autonomous rescue system includes the waterborne autonomous rescue device which is further connected to a monitoring device; a monitoring personnel can check the status of the waterborne autonomous rescue device through the monitoring device. When a drowning incident occurs, the monitoring personnel can go to a location of the waterborne autonomous rescue device to carry out subsequent rescue.

Abstract: It has been found that by generating multiple nicks in the DNA region proximal to a specific site of homologous chromosomes, DNA exceeding 100 bp can be deleted in one of the homologous chromosomes.

Abstract: Provided is a driving device for detecting mechanical characteristics and electrical characteristics of cells. A structure of the driving device includes a piezoelectric stack, a bridge-type flexible hinge mechanism, a parallel hinge mechanism, a lead screw guide rail, a stepping motor, a linear displacement sensor, a force sensor, a ceramic needle, a first electrode, a second electrode, a cell container, an XY axis displacement platform, a positioning hole, a first metal base, a second metal base, a first metal connecting plate, a second metal connecting plate, a first pre-tightening wedge, a second pre-tightening wedge, screws, and a pre-tightening screw. During the operation of the driving device, the piezoelectric stack is driven under an excitation effect of a driving electric field signal, such that the bridge-type flexible hinge mechanism stretches, and the ceramic needle is driven by the parallel flexible hinge mechanism to move downwards.

Abstract: DNA is sequenced by (a) independently sequencing first and second strands of a dsDNA to obtain corresponding first and second sequences; and (b) combining the first and second sequences to generate a consensus sequence of the dsDNA. By independently sequencing first and second strands the error probability of the consensus sequence approximates a multiplication of those of the first and second sequences.

Abstract: A bone regeneration material is formed by a complex. The complex includes: a base material including octacalcium phosphate; and functional molecules, adsorbed to the octacalcium phosphate.

Abstract: An optical architecture for enhancing phase modulation depth for a phase light modulator includes a laser light source, a 4f, 1:1 relay where a tilted mirror with a center hole is placed at the backfocal point of the first lens. A vertically polarized (VP) and collimated light is deflected by a polarized beam splitter (PBS), followed by passing through a Quarter Wave Plate (QWP) that converts linear polarization (LP) to right circular polarization (RCP). Upon interaction of the RCP light with PLM, spatial phase is modulated by 2kd(i,j). PLM reflects and modulates phase of light while changing the handness of polarization from RHP to left hand circular polarization (LCP). The 2nd interaction with QWP changes polarization of light from LCP to horizontally polarized (HP) light. The mirror M1 is placed at a half of the Talbot distance from the PLM as described later. The reflected light by M1 is a HP light, therefore it goes through the PBS and is converted to RCP by the 3rd interaction with QWP.

Abstract: The method of manufacturing a copper foil with a high elongation rate includes: preparing a plating solution by mixing a copper ion, an additive for improving conductivity, a plating inhibitor, and a plating accelerator; and manufacturing the copper foil by immersing a substrate in the plating solution and applying an electric current to the plating solution to electroplate the copper foil on a surface of the substrate.

Abstract: Disclosed are a traffic prediction method for a metropolitan optical network and related devices. The traffic prediction method may include: classifying nodes in the metropolitan optical network into multiple node sets based on locations of the nodes; for nodes in each node set, inputting temporal traffic data of the nodes into a traffic prediction model corresponding to the node set to obtain traffic prediction results of the nodes in the node set. In the method, the traffic prediction model is obtained by deep learning using historical time-series traffic data of the node sets as a training set.

Abstract: Disclosed herein are methods to make hydrogen titanium oxide (HxTiyOz) compositions. The nano-HxTiyOz can be used to remove pollutants and recover valuable materials. For example, the nano-HxTiyOz can be used to isolate lithium from various aqueous mixtures, such as brines, seawater, oil gas-produced water, and lithium battery waste solutions.

Abstract: Among the various aspects of the present disclosure is the provision of methods for inhibiting neuronal activity in NF1 tumors. One aspect of the disclosure provides for a method of inhibiting tumor growth comprising administering a neuronal activity inhibiting agent to a subject in need thereof. Another aspect of the disclosure provides for a method of attenuating neuronal excitability, activity-regulated mitogen production, and tumor progression comprising administering a neuronal activity inhibiting agent to a subject in need thereof. Yet another aspect of the disclosure provides for a method of activating HCN channels in a subject comprising administering a neuronal activity inhibiting agent to a subject in need thereof. Yet another aspect of the disclosure provides for a method of treating brain or and nerve tumors in Neurofibromatosis type 1 (NF1) comprising administering a neuronal activity inhibiting agent to a subject in need thereof.

Abstract: A method is described for improving water retention in soil, which involves mixing a super absorbing resin (SAR) composite with the soil. The SAR composite comprises a natural pozzolan and at least one polymer or copolymer. The SAR composite may be in the form of granules having an average longest dimension of 0.2-10 mm, though the SAR composite may be pelletized or formed in other sizes. The SAR composite may release water at a faster rate in a soil when exposed to drought conditions.

Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo. This disclosure also relates to recombinant adeno associated virus (rAAV) capsid proteins comprising one or more amino acid substitutions in the 5-fold region of the rAAV capsid that result in decreased reactivity to neutralizing antibodies, and their use as gene delivery vehicles.

Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.

Abstract: Disclosed are compositions and methods related to RNA interference (RNAi) and the use of RNAi active sequence for treating diseases and disorders. Particular disclosed are toxic RNAi active sequences such as siRNA and shRNA for killing cancer cells. The disclosed toxic RNAi active sequences typically include trinucleotide repeats and preferentially target the expression of multiple essential genes for cell survival and/or growth.

Abstract: The present application belongs to the technical field of proteolysis-targeting chimeras (PROTACs), and discloses a PROTAC molecule and a preparation method and use thereof. A ligand for a target protein in the PROTAC molecule of the present application is a pyridine carboxylic acid-1-oxide derivative. In cell and zebrafish experiments, the PROTAC molecule exhibits no toxic and side effects at a drug concentration allowing a desired effect. At a cellular level, an inhibition level of the PROTAC molecule for human tyrosinase (TYR) reaches less than or equal to 1 ?mol/L. The PROTAC molecule in the present application can significantly reduce the generation of melanin by degrading TYR, and has excellent solubility, safety, and efficacy and a low effective concentration.

Abstract: A method of forming an electrode material includes: (1) loading an electrochemically active material onto graphene sheets; (2) combining the electrochemically active material-loaded graphene sheets with holey graphene oxide sheets to form a mixture; and (3) treating the mixture under reducing conditions to form a composite including a graphene framework loaded with the electrochemically active material.

Abstract: A sequence time window amplitude-phase-frequency characteristics analysis method and system for underwater vehicle power frequency electromagnetic field disturbance are provided. The method includes: establishing a power grid dipole group model, emulating and calculating to obtain background field intensity data of a test location, and constructing an emulated background field database; acquiring measured background field data, comparing the emulated data with the measured data, and providing a relative error; calculating a background field intensity and underwater vehicle target disturbance under the action of the above dipole group, and establishing a measured target signal database; and performing actual measurement according to an underwater vehicle motion and detection topology, performing a Fourier transform and Fourier sliding window decomposition after acquiring original data, and acquiring an amplitude spectrum and a spectrogram of an underwater vehicle target disturbance signal.

Abstract: An optimization method for bending rebound quantity of aluminum roll forming includes the following steps: S1, analyzing the process of aluminum roll forming, and determining decision variables of aluminum rebound quantity and thickness reduction; S2, constructing the optimization model of the bending rebound quantity of aluminum roll forming based on the multi-objective optimization algorithm and clarifying constraints in the process of aluminum roll forming; S3, based on characteristics of the model in S2, proposing the corresponding algorithm to optimize the aluminum rebound quantity and thickness reduction; S4, updating the decision variables that affect the aluminum rebound quantity and thickness reduction; S5, judging the iteration stop condition, and outputting the scheme that improves the bending rebound quantity of roll forming aluminum.