Abstract: A power conversion device comprises: power conversion circuitry for converting DC power into AC power and supplying it into a load according to a switching state quantity defined by combinations among switching parameters of switching devices; a voltage output calculation device for calculating a voltage output value on the power conversion circuitry, based on the switching state quantity; an integration value calculation device for acquiring a voltage reference integration value and a voltage output integration value by integrating a voltage reference value and the calculated voltage output value; a switching update-determination unit for outputting an update signal of the switching state quantity, based on the voltage reference integration value, its allowance value, and the voltage output integration value; and a switching determination table for determining a switching state quantity of the switching devices, based on the voltage reference integration value, the voltage output integration value and the up

Abstract: A method of diagnosing Alzheimer's disease and related dementias (ADRD) in a patient comprising obtaining a plasma sample from the patient; determining a level of a biochemical sulfide in the plasma sample from the subject by trapping volatilized H2S in the plasma sample using alkaline buffer with monobromobiamine, and detecting the level of biochemical sulfide in the plasma sample, the biochemical sulfide being one of acid-labile sulfide, bound sulfide, and total sulfide; and diagnosing the patient with ADRD when the level of the biochemical sulfide is at least an elevated threshold level for the biochemical sulfide.

Abstract: The present invention relates to the field of intelligent vehicles, and more specifically, to a human-machine shared control method based on trajectory prediction. It comprises: establishing a road-vehicle model based on vehicle-related parameters and then designing a path-tracking controller; further predicting the driver's driving trajectory, evaluating the driving risk, and switching the control power between the automatic system and the human driver based on the driving risk. The present invention ensures that when the driver's inputs will cause high risk to the vehicle, the driver's input is deprived of; and that when the driver's driving inputs will not cause high risk to the vehicle, the driving is carried out by the driver, so that in the case where the automatic system is having a problem, the driver can effectively realize a safe intervention, and the safety of the intelligent driving is improved.

Abstract: A tRNA that hybridizes to a non-optimal codon can be used to increase expression in a mammalian cell of a gene product encoded by a gene containing the non-optimal codon or to treat a haploinsufficiency disorder in a subject having a haploinsufficient gene containing the non-optimal codon.

Abstract: The present disclosure relates to a device and process for preparing sebacic acid through electromagnetic induction heating coupled with dry constant-temperature alkaline hydrolysis. The device includes an electromagnetic heating cylinder and a reaction kettle arranged in the electromagnetic heating cylinder, heat storage pellets fill space between the reaction kettle and the electromagnetic heating cylinder, and the heat storage pellets adhere to an inner wall of the electromagnetic heating cylinder and an outer wall of the reaction kettle. The upper end of the reaction kettle is provided with a feeding port, a gas outlet and a temperature measuring port, the reaction kettle is also provided with a stirring device, a lower portion of the reaction kettle is provided with a discharging port, and the feeding port, the gas outlet, the temperature measuring port and the discharging port all extend out of the thermal insulation cotton.

Abstract: The present disclosure relates to a method that includes utilizing a microorganism for the converting of a substrate to an acid contained in a mixture that includes the acid and water, maintaining a pH of the mixture to less than 5, and treating the mixture with a first stream comprising an organic.

Abstract: A process for preparing a modified heat-treated platelet pellet lysate, said process comprising the steps of: a) Providing a platelet pellet lysate, b) Heat-treating the platelet pellet lysate at a temperature of 55° C. to 65° C. during 20 to 40 minutes, c) Purifying the heat-treated platelet pellet lysate of step b) so as to obtain a modified heat treated platelet pellet lysate having a total protein content of less than 70% of the total protein content of the platelet pellet lysate of step a).

Abstract: Provided herein is a percutaneous expandable venous cannula device, and related methods. The device is easily inserted, for example, using standard Seldinger technique via the right internal jugular. The device includes multiple, multi-holed limbs that softly fill, e.g., the right atrium to facilitate complete drainage, enable retraction of the chamber in surgery, and mitigate suction occlusion, filling the entire atrium and allowing for efficient and rapid emptying of the chamber. In aspects, the device facilitates minimally-invasive aortic or mitral valve surgery with single placement via the right internal jugular as the sole cannula needed for full support.

Abstract: Disclosed herein is a class of molecules termed remodilins that are effective in treating asthma, pulmonary fibrosis, and associated disorders. The molecules ameliorate asthma and pulmonary fibrosis symptoms by various mechanisms, including inhibiting airway smooth muscle contractile protein accumulation, reducing airway constrictor hyperresponsiveness, inhibiting bronchial fibroblast transformation into myofibroblasts, and/or treating or preventing airway or pulmonary fibrosis.

Abstract: The present application provides an underwater-wellhead feeding tool assembly and a use method thereof. The device controls a controller to add pressure to an inside of a drive cylinder through a first pipeline via a first port, and to add pressure to a cavity apace between a pressure-bearing cylinder and the drive cylinder through a first branch line; the controller controls, through a third branch line, the drive device to transmit a torque to the underwater wellhead feeding tool, and transmit, through a second branch line, an axial force to the underwater wellhead feeding tool; and then a sensing component transmits a detected stress signal and/or strain signal to a data acquisition device through a test lead, thereby testing and analyzing an effect of different force field conditions on mechanical behaviors and performance of the underwater wellhead feeding tool.

Abstract: The present disclosure describes digital watermark detection systems and methods. In one such system, a plurality of intellectual property cores are integrated on a system-on-chip, such that the intellectual property cores comprise a first intellectual property core and a second intellectual property core. The system further includes a first network interface connected to the first intellectual property core that can encode a first digital watermark into a packet stream designated for the second intellectual property core. The system further includes a second network interface connected to the second intellectual property core that can receive the packet stream and decode the packet stream to generate a second digital watermark. The second network interface is further configured to perform a validation test on the packet stream and deliver the packet stream to the second intellectual property core when the first digital watermark is determined to match the second digital watermark.

Abstract: A method and system for 3D contour reconstruction of AM parts based on light field imaging, belonging to the field of image reconstruction technology is provided. The method includes constructing an EPI-UNet framework, where a preset light field dataset is used to construct a training set, learning labels from the disparity maps corresponding to the preset light field dataset are obtained, and EPI-UNet framework is trained to obtain a predicted disparity vector with the training set and learning labels. Two mappings including disparity and depth mapping, and disparity and 3D mapping, are established to get 3D contour of the AM part. The experiments of validation for accuracy and 3D contour reconstruction of AM parts were performed. By applying light field multi-view vision to the AM process and combining the rich angle and spatial domain view information of the light field, this disclosure provides a reliable quality assurance for AM monitoring.

Abstract: A wearable haptic modulation device for real-time simulation of texture properties of a material surface in mixed reality environments is provided. Particularly, it includes a U-shaped pneumatic actuator surrounds a user's fingertip, a finger-housing support creating a space for fingertip containment, a resonant actuator on the finger-housing support generating vibrotactile feedback to enhance perceived roughness on touched physical surfaces, and a pneumatic control system generating pneumatic actuation to reduce the perceived roughness on touched physical surface. Notably, the U-shaped pneumatic actuator allows direct contact of the user's fingerpad with the touched physical surface.

Abstract: A method and system for quantifying semantic variance between neural network representations is provided. Two neural network representations to be compared are first extracted, the weight of each filter in an intermediate layer corresponding to each semantic concept is learned on a reference dataset using the Net2Vec method, then set IoU of each representation for all semantic concepts in the reference dataset are calculated, and finally variance between the set IoU of the two representations for all the semantic concepts are integrated to obtain semantic variance between the two neural network representations. The method solves the problem of lack of accurate measurement on the variance between neural network representations on a semantic information level, and has an accurate measurement effect.

Abstract: An operating circuit and an operating method of a resistive random-access memory are provided, the operating circuit includes: at least one capacitance connected in series with the resistive random-access memory, so that the resistive random-access memory is grounded through the at least one capacitance. The operating method includes: connecting at least one capacitance in series with a resistive random-access memory, so that the resistive random-access memory is grounded through the capacitance; applying a forming pulse voltage or a set pulse voltage on the resistive random-access memory to achieve a forming operation or a set operation of the resistive random-access memory.

Abstract: The present invention provides a recombinant Vaccinia virus as a dengue virus vaccine that can be used as a therapeutic or prophylactic agent in the clinic. This recombinant Vaccinia virus is characterized by including: all or part of a cDNA that encodes a non-structural protein from a dengue virus; and an expression promoter.

Abstract: The present disclosure refers to direct current-to-direct current (DC-DC) converters and power supplies including the same. In an embodiment, a DC-DC converter includes a first switching circuit, a second switching circuit, a fourth capacitor coupled to a second node, and an inductor-capacitor (LC) filter coupled to a third node. The first switching circuit includes a first transistor coupled between a first capacitor and an input node, a second transistor coupled between the first capacitor and a second capacitor, a third transistor coupled between a first node and a third capacitor, and a fourth transistor coupled between the third capacitor and a ground node. The second switching circuit includes a fifth transistor coupled between the second capacitor and the third capacitor, a sixth transistor and a seventh transistor coupled between the first capacitor and the third capacitor, and an eighth transistor coupled between the first capacitor and the ground node.

Abstract: A particulate mesoporous nanocomposite having the general formula ZrO2·Mg6MnO8, wherein the nanocomposite comprises a monoclinic zirconium dioxide (ZrO2) crystalline phase, a tetragonal ZrO2 crystalline phase, and a cubic magnesium manganese oxide (Mg6MnO8) crystalline phase. The nanocomposite may be obtained by a method comprising: forming an aqueous mixture by adding an aqueous solution of a chelating agent into an aqueous solution of a magnesium salt, a manganese salt and a zirconium salt; adding a polyol in the aqueous mixture to form a gel; heating the gel under stirring at a temperature of about 200° C. to about 400° C. for a sufficient duration to form a dry powder; and, calcining the dry powder at a temperature of about 700° C. to about 1000° C. to form the nanocomposite material.

Abstract: A renal tube assay device can include: a container having an inlet port and an outlet port; a matrix material in the container; and a lumen in the matrix material extending from the inlet port to the outlet port. The lumen can include a luminal surface with at least one low density region that has a lower density compared to another adjacent region of the matrix material that is located at least partially around the at least one low density region. The low density region can have a form of a bubble, bulge, capsule, or the like. The low density region can bulge into the lumen. A port can be adapted for receiving a pipette tip. The matrix material can include a hydrogel. The container can be located in a cell culture dish.

Abstract: Provided is a series of homologous small molecule immune agonists and novel bifunctional immune targeting compounds having targeting and immune activation functions, which are obtained by coupling the small molecule immune agonists to targeting drugs. The resulting immune targeting compounds are beneficial for enhancing immune activation effects, and anti-tumor and other disease fighting effects of the targeting drug. The enhanced effect is produced from a synergy of immunological anti-tumor factors (such as IFN-?) and inhibition at pathogenic targeting sites.