Patents Assigned to The University
  • Non-invasive ocular analyte sensing system
    Patent number: 9456772
    Abstract: A noninvasive method and apparatus for determining analyte concentration (e.g., glucose) in a subject that includes measuring light refraction from at least a portion one or more structures. One example of such structure is the subject's iris.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: October 4, 2016
    Assignee: The University of Toledo
    Inventors: Brent D. Cameron, Anthony J. Webb
  • Polyethylene glycol-based dendrons
    Patent number: 9457099
    Abstract: The instant invention relates to polyethylene glycol-based dendrons, otherwise known as PEGtide dendrons, compositions thereof and methods of use.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: October 4, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Jieming Gao, Yashveer Singh, Xiaoping Zhang, Matthew S. Palombo, Stanley Stein
  • Unified motion planning algorithm for autonomous driving vehicle in obstacle avoidance maneuver
    Patent number: 9457807
    Abstract: A method for automated lane centering and/or lane changing purposes for a vehicle traveling on a roadway that employs roadway points from a map database to determine a reference vehicle path and sensors on the vehicle for detecting static and moving objects to adjust the reference path. The method includes reducing the curvature of the reference path to generate a reduced curvature reference path that reduces the turning requirements of the vehicle and setting the speed of the vehicle from posted roadway speeds from the map database. The method also includes providing multiple candidate vehicle paths and vehicle speeds to avoid the static and moving objects in front of the vehicle.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: October 4, 2016
    Assignees: GM Global Technology Operations LLC, Carnegie Mellon University
    Inventors: Jin-Woo Lee, Upali Priyantha Mudalige, Tianyu Gu, John M. Dolan
  • Methods for treating polycystic kidney disease
    Patent number: 9457016
    Abstract: Methods for treating autosomal dominant polycystic kidney disease (ADPKD) are described herein. More particularly, methods described herein relate generally to administering glutaminase1 inhibitors to subjects afflicted with ADPKD. Accordingly, the use and application of compounds or agents that inhibit glutaminase1 for treating ADPKD or for use in a medicament for treating ADPKD are encompassed herein.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: October 4, 2016
    Assignee: New York University
    Inventors: Edward Skolnik, Zhai Li
  • Training simulator for mechanical ventilation
    Patent number: 9460639
    Abstract: A diaphragm respiratory signal simulator is activated by skin voltage that is coupled to the simulator by many ways such as but not limited to a user sliding a finger over a conductive surface, the user sliding a finger over surfaces close to the conductive element, touch or sliding the finger over the ventilator screen. The conductive surface is electrically connected to a ring electrode at a distal part of a manikin's esophagus. The diaphragm respiratory signal simulator produces a synthetic diaphragm electrical signal that triggers a ventilator to deliver a supported breath, which is proportional to the strength of the generated signal. This process allows safe and successful training on the operations of NAVA mode of ventilation and catheter positioning.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: October 4, 2016
    Assignee: University of Dammam
    Inventor: Ahmed Abdelkarim Mansi
  • Method for distributing a list of certificate revocations in a vanet
    Patent number: 9461827
    Abstract: In a vehicle-to-vehicle wireless communication system utilizing certificates to verify trustworthiness of received communications, a method for distributing a list of certificate revocations to vehicles in the communication system. At least one main station transmits a list of certificate revocations to at least one vehicle and the vehicle thereafter transmits the list of certificate revocations to other vehicles in the communication network. Each of the other vehicles in the communication network updates its list of certificate revocations in response to the receipt of the list of certificate revocations from another vehicle in the system. The other vehicles thereafter transmit their updated list of certificate revocations to other vehicles in the system.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: October 4, 2016
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., The Board of Trustees, University of Illinois at Urbana-Champaign
    Inventors: Kenneth P. Laberteaux, Yih-Chun Hu, Jason Haas
  • Immunomodulating compositions and methods of use thereof
    Patent number: 9457047
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: October 4, 2016
    Assignees: Whitehead Institute, Massachusetts Institute of Technology, Trustees of Boston University, The General Hospital Corporation
    Inventors: Ifat Rubin-Bejerano, Gerald R. Fink, Claudia Abeijon, Daniel S. Kohane, Jason E Fuller, Robert S. Langer
  • Materials and design for an electrocatalytic device and method which produces carbon nanotubes and hydrocarbon transportation fuels
    Patent number: 9458542
    Abstract: The present teachings are directed toward an electrocatalytic cell including a barrier, having at least a first side and a second side opposite the first side, comprising a material permeable to oxygen ions and impermeable to at least CO2, CO, H2, H2O and hydrocarbons, an electrical power supply in communication with the barrier, a catalyst adjacent the first side of the barrier, a supply of feedstock components in communication with the first side of the barrier, a supply of a carrier gas component in communication with the second side of the barrier; wherein the feedstock components contact the catalyst and react to form hydrocarbon-containing components and oxygen-containing components, and the electrical power supply biases the barrier to thereby conduct oxygen ions from the first side to the second side. Also presented are a device and methods for producing carbon nanotubes.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: October 4, 2016
    Assignees: Honda Motor Co., Ltd., University of Connecticut, The
    Inventors: Steven L. Suib, Christopher James Brooks, Samuel Frueh, Boxun Hu, Eric Rolland Kreidler
  • Hydrogels for delivery of therapeutic polypeptides
    Patent number: 9457101
    Abstract: Disclosed herein is a hydrogel composition comprising a polymer covalently linked to glutathione (GSH). Also disclosed herein is a method for providing localized delivery of one or more agents in a subject suffering from a disease. The method comprises administering to the subject a GST/GSH affinity hydrogel comprising a therapeutically effective amount of the one or more agents.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: October 4, 2016
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Richard Gemeinhart, Jason Buhrman, Jamie Rayahin
  • Method for chemical vapor identification using swelling-based sensors
    Patent number: 9459223
    Abstract: The method for chemical vapor identification using swelling-based sensors uses an apparatus that having a first gas chamber including a gas inlet port for inletting a hydrocarbon vapor to be analyzed; a second gas chamber having a hydrocarbon vapor outlet port for exiting the vapor; a chemical sensor placed inside the first and the second gas chambers; and a thermometer placed inside the first and the second gas chambers for measuring the internal temperature; wherein the second gas chamber is placed at a lower temperature compared with the first chamber; and wherein the first gas chamber is in communication with the second chamber by a pipe for transmitting the hydrocarbon vapor from the first chamber to the second chamber.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: October 4, 2016
    Assignee: KING SAUD UNIVERSITY
    Inventors: Hadi Rasam Alqahtani, Martin F. Grell
  • Stream-switching in a content distribution system
    Patent number: 9462306
    Abstract: Stream-switching techniques are applied in a content delivery system. A merge frame is generated as a function of bit-rates, distortion, and a piecewise constant operator. Parameters of the piecewise constant operator are selected to optimize the merge frame. Data streams are switched based on bandwidth requirements, switch requests, and throughput of a network. Images are reconstructed based on the merge frames and prediction frames. Reconstructed images are identically reconstructed for any prediction frame based on the merge frame.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: October 4, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Oscar Chi Lim Au, Wei Dai, Gene Cheung, Ngai Man Cheung, Antonio Ortega Diego
  • Manipulating microRNA for the management of neurological diseases or conditions and compositions related thereto
    Patent number: 9458458
    Abstract: This disclosure relates to manipulating microRNA for the management of neurological disorders and compositions related thereto. In certain embodiments, the disclosure contemplates inhibition of miR324 or miR324-5p, e.g., the use of nucleobase polymers for antisense disruptions or RNA interference of miR-324 expression or for miR324-5p binding in order to increase Kv4.2 expression. In certain embodiments, the disclosure relates to methods of treating or preventing a neurological disease or condition comprising administering an effective amount of an inhibitor to a subject in need thereto.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: October 4, 2016
    Assignee: Emory University
    Inventors: Gary J. Bassell, Xiaodi Yao, Christina Gross
  • Nano-seaurchin contrast agents with pore-filled gold nanorods and the preparation method thereof
    Patent number: 9457105
    Abstract: A nano-photoacoustic imaging agent is disclosed. The nano-photoacoustic imaging agent includes a porous carrier and a gold filling material embedded in the porous carrier. A method for the preparation of the nano-photoacoustic imaging agent is also provided.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: October 4, 2016
    Assignee: National Chiao Tung University
    Inventors: San-Yuan Chen, Po-Jung Chen, Dean-Mo Liu, Shang-Hsiu Hu
  • Active manipulation of electromagnetic wave propagation in metamaterials
    Patent number: 9459375
    Abstract: An apparatus for controlling propagation of an electromagnetic wave includes a metamaterial having an array of cells, each cell containing a metallic structure having a resonant frequency; a plurality of devices integrated in the metamaterial, each of said devices being in electrical communication with a metallic structure in a cell in the array of cells; and a controller for electrically activating each of said plurality of devices to cause said resonant frequency to change, thereby causing at least one of a permeability and permittivity of the metamaterial to change.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: October 4, 2016
    Assignees: TUFTS UNIVERSITY, TRUSTEES OF BOSTON COLLEGE
    Inventors: Sameer Sonkusale, Willie John Padilla, Saroj Rout
  • Control device, control method and control program
    Patent number: 9457467
    Abstract: A control device includes a main actuator configured to drive a plant through a torque transfer device disposed on a driving side, a load side sub-actuator configured to drive the plant that is disposed on a plant side, and a processor configured to: generate a torque reference input value driving the main actuator and the load side sub-actuator, and cancel out resonance by multiplying the generated torque reference input value by: a first gain including an inertia coefficient, a viscosity coefficient, and a reduction ratio of the torque transfer device on the driving side and on the plant side, and a second gain including: the inertia coefficient, the viscosity coefficient, and the reduction ratio of the torque transfer device on the driving side and on the plant side, and thereby adjusting a ratio of the torque reference input value of the main actuator and the load side sub-actuator.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: October 4, 2016
    Assignees: THE UNIVERSITY OF TOKYO, TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Hiroshi Fujimoto, Kenji Inukai, Taro Takahashi
  • Adeno-associated virus virions with variant capsid and methods of use thereof
    Patent number: 9458517
    Abstract: The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via intravitreal injection, compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: October 4, 2016
    Assignee: The Regents of the University of California
    Inventors: David V. Schaffer, Ryan R. Klimczak, James T. Koerber, John G. Flannery, Deniz Dalkara Mourot, Meike Visel, Leah C. T. Byrne
  • Engineered cellular pathways for programmed autoregulation of differentiation
    Patent number: 9458471
    Abstract: The present invention provides compositions and methods for programming mammalian cells to perform desired functions. In particular, the present invention provides compositions and methods for programming stem cells to differentiate into a desired cell type. A quorum sensing systems that regulates the expression of cell fate regulators is introduced into mammalian host cells, such as stem cells. The quorum sensing systems generally comprises vectors that express the components of a bacterial quorum sensing pathway, including proteins which catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer, and vectors in which genes encoding cell fate regulators are operably linked to a promoter induced by the autoinducer/regulatory partner complex.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: October 4, 2016
    Assignee: The Trustees of Princeton University
    Inventors: Ron Weiss, Ihor Lemischka, Priscilla Purnick, Christoph Schaniel, Miles Miller, Patrick Guye
  • Methods for producing enteroendocrine cells that make and secrete insulin
    Patent number: 9457079
    Abstract: Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more Foxo proteins or biologically active fragments or variants thereof.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: October 4, 2016
    Assignee: The Trustees Of Columbia University In The City Of New York
    Inventors: Chutima Talchai, Domenico Accili
  • Methods and compositions for producing aluminum tolerant alfalfa
    Patent number: 9456561
    Abstract: The invention relates to alfalfa plants and lines having aluminum tolerance. The invention also relates to parts of alfalfa plants from lines having aluminum tolerance, including seeds capable of growing aluminum tolerant alfalfa plants. Methods for the use and breeding of aluminum tolerant alfalfa plants are also provided.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: October 4, 2016
    Assignees: The Samuel Roberts Noble Foundation, Inc., The University of Georgia Research Foundation, Inc.
    Inventors: Dong-Man Khu, Joseph H. Bouton, Maria J. Monteros, Rafael Reyno, E. Charles Brummer
  • Methods and apparatuses for generating a steerable pressure field in a shock wave lithotripter
    Patent number: 9456835
    Abstract: Lithotripter apparatuses and methods are provided for selectively modifying an acoustic pressure field and can include a shock wave source operable to generate a shock wave having a substantially axisymmetric acoustic pressure field, an acoustic focusing member positioned between the shock wave source and a target, and an acoustic barrier positioned between the shock wave source and the acoustic focusing member. The acoustic barrier can be operable to selectively block a portion of the shock wave generated by the shock wave source such that the substantially axisymmetric pressure field is transformed into a modified acoustic pressure field.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: October 4, 2016
    Assignee: DUKE UNIVERSITY
    Inventors: Pei Zhong, Walter Neal Simmons, Georgy N. Sankin, Nathan Smith, Franklin Hadley Cocks, Glenn M. Preminger