Abstract: The present invention aims to provide a mesenchymal stem cell attractant capable of attracting a mesenchymal stem cell; and others. The present invention provides a mesenchymal stem cell attractant containing at least one selected from the group consisting of an extract of a Bodhi tree, an extract of the root bark of Paeonia suffruticosa Andrews, an extract of Mallotus philippinensis, an extract of Uncaria gambir an extract of Pashanbheda, and an extract of a plant belonging to the genus Prunus.

Abstract: Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a fatty acid, and/or an alcohol (e.g., ethanol). In various aspects these components may synergistically act to kill or reduce the growth of microbes, such as bacteria or fungi, present in a biofilm.

Abstract: The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.

Abstract: A method of preparing an epitope for a secondary antibody detected protein tag, comprising: constructing a expressing vector, comprising a nucleotide sequence for encoding the secondary antibody detected protein tag comprising at least one epitope selected from at least one primary antibody which is detected by corresponding secondary antibody; expressing the vector in a host cell; and obtaining the secondary antibody detected protein tag which is expressed in the host cell. Further, a method for constructing a protein molecular weight marker ladder, comprising constructing a plurality of recombinant protein tags with different molecular weights, wherein each the recombinant protein tag comprises at least one epitope of primary antibody. Besides, a secondary antibody detected protein tag comprises at least two peptide sequences of epitopes selected from primary antibodies of at least two different species.

Abstract: The present invention relates to liquid entrapping devices (e.g., absorbent non-woven fibrous mats) and to a process for preparing such devices. More particularly, the present invention relates to mechanically strong absorbent materials made from such liquid entrapping devices (e.g., non-woven fibrous mats) and to a method for preparing same. In one embodiment, a liquid entrapping device of the present invention comprises at least one hydrophilic elastomeric fibrous component (HEFC) and at least one wetting agent component. In another embodiment, a liquid entrapping device of the present invention comprise at least one hydrophilic elastomeric fibrous component (HEFC), at least one absorbent component, and at least one wetting agent component. In one instance, the wetting agent component of the present invention is contained on and/or within the fibers and/or nanofibers that form the liquid entrapping device (e.g., a non-woven fibrous mat) of the present invention.

Abstract: The present invention relates to a pharmaceutical composition comprising an anti-cancer drug and an inhibitor of bone morphogenetic protein 4 (BMP-4) or its gene expression. The present invention also relates to methods of treating cancer and prognostic methods.

Abstract: The present invention relates to the field of neurology. More specifically, the present invention provides methods and composition useful for treating neuropathic pain. In a specific embodiment, the present invention provides a recombinant Kcna2 sense fragment. In another embodiment, the present invention provides a method of treating neuropathic pain comprising the step of administering a composition comprising a recombinant Kcna2 sense fragment.

Abstract: The present invention relates to the field of viral gene therapy. More specifically, the present invention provides compositions and methods for retargeting virus constructs. In one embodiment, the present invention provides an adenoviral construct comprising a nucleic acid encoding the peptide sequence MAE-X-PDP (SEQ ID NO:45), wherein X is an antigen targeting peptide. In a more specific embodiment, an adenoviral construct comprises a nucleic acid sequence encoding the peptide sequence MAEWQPDTAHHWALTLPDP (SEQ ID NO:10) inserted into the HI-loop of adenovirus fiber protein.

Abstract: A water absorption property of a concrete surface of an actual structure is measured in situ for clarification and evaluation of causative factors and so forth related to densification of surface layer concrete. An apparatus for a water absorption test has a position-fixing device, a detecting device and a measuring device. A device for water absorption test having vent means is positionally fixed on the concrete surface by the position-fixing device, with use of negative pressure or a mechanical connection. The detecting device detects an amount of water held in a chamber, and results detected by the detecting device are input into the measuring device. A water absorption rate is measured by the detecting device and the measuring device. On the basis of the water absorption rate measured at predetermined elapsed time, identification or comparison of causative or evaluative factors related to densification of the surface layer concrete is carried out.

Abstract: The present invention discloses a dual-vortical-flow hybrid rocket engine, including a main body and a nozzle communicating with an end of the main body. The main body includes a plurality of disk-like combustion chambers arranged longitudinally, and a central combustion chamber formed along the axial portion and communicating the disk-like combustion chambers. Each of the disk-like combustion chambers is provided with a plurality of oxidizer injection nozzles at its inner circumference surface. Inside the disk-like combustion chambers, the oxidizer is injected in nearly the tangent directions of the circumference, and the injection directions are opposite for the neighboring disk-like combustion chambers, which creates vortical flows with opposite rotating directions so as to increase the total residence time of the combustion reactions of the oxidizer and the solid-state fuel in the disk-like combustion chambers of the present invention.

Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.

Abstract: The present invention includes bis- and tris-benzamide compounds that block AR signaling and have activity against prostate cancer. Uses for these compounds, and pharmaceutical compositions containing the same, also are provided.

Abstract: Dimethyl trisulfide antidote compositions may be used to as a cyanide poisoning antidote. Formulations of dimethyl trisulfide may be made in an aqueous solvent system that includes water and one or more of a co-solvent, a surfactant, a cyclodextrin, and a phospholipid.

Abstract: The present technology comprises a method and apparatus for a routing protocol for a router including an apparatus and method for distance vector multicast routing. The method and apparatus as disclosed and claimed offers a new interpretation of the routing information stored in a DVMRP routing table. This interpretation relates to the knowledge of the locations of a multicast source router and the routers connected to hosts with group members in a DVMRP domain. The methodology exploits this knowledge to create two conditional packet forwarding checks, based on pseudo-diameter and super-pseudo-diameter respectively, and used these conditions to extend the two phases of the existing DVMRP to improve its performance from the viewpoint of much better utilization of bandwidth.

Abstract: Present embodiments provide efficient and cost-effective use of chloramines such as monochloramine, NH2Cl, to degrade styrene butadiene rubber, a material from which tires and other products are made, so that it can be recycled, and do so by overcoming the limitations of monochloramine due to its thermodynamic instability by achieving and maintaining adequate monochloramine concentrations for the degrading process.

Abstract: A physical environment is equipped with a plurality of non-obtrusive sensors (e.g., motion sensors). As a plurality of residents perform various activities within the physical environment, sensor readings are received from one or more of the sensors. Based on the sensor readings, each of the plurality of residents is identified and locations of each of the plurality of residents are tracked.

Abstract: The present disclosure provides compositions and methods for increasing bone growth and/or enhancing wound healing, for example, fracture repair. The disclosure provides recombinant nucleic acids useful for promoting bone growth. For example, the disclosure provides recombinant nucleic acids that encode a fibroblast growth factor-2 (FGF-2) analog. The disclosure also provides vectors and cells incorporating these nucleic acids, as well as FGF-2 analogs encode by them. The disclosure also provides a mouse system of bone marrow transplantation and methods for producing as well as methods for using the system. Methods for inducing division and/or inducing differentiation of a hematopoietic stem cell are also provided, as are methods for enhancing bone growth and/or wound repair (for example, fracture repair).

Abstract: In various embodiments, the invention provides phosphine ligand supported first row metal catalysts with surprising and efficacious catalytic activity for hydrosilylation of pi-bonded substrates. Also provided are methods of using the catalysts of the invention to prepare hydrosilylated compounds.

Abstract: A high efficiency plant expression promoter from Capsicum annuum serine hydroxymethyl transferase gene and uses thereof. This high efficiency plant expression promoter and 5?-untranslated region (5?-UTR) from Capsicum annuum serine hydroxymethyl transferase gene, a high efficiency plant expression vector having the same, a plant transformed with the vector, a process for high efficiency expression of a foreign gene by using the vector and a transformed plant which expresses with high efficiency a foreign gene based on the process and seeds of the transformed plant.

Abstract: A method for making an orthopaedic implant, the method comprising: characterizing at least a portion of a bone corresponding to the bone to be replaced, said corresponding bone being on the contralateral side of the patient; providing a model of the orthopaedic implant based on a mirror image of the contralateral bone; and forming the orthopaedic implant based on the model.