Abstract: Methods for operating a mass spectrometer having a skimmer and a circuit configured to apply an electric potential to the skimmer comprise obtaining an initial mass spectrum of a sample and measuring a value indicating an ion beam intensity of one or more ion species. A varying DC electric potential is applied to the skimmer to identify an operational electric potential, wherein the DC electric potential is varied until the value indicating the ion beam intensity of the one or more ion species changes by a predetermined amount. The mass spectrum with the operational electric potential applied to the skimmer is output. In some examples, a pressure within the mass spectrometer is varied to identify an operational pressure, and the mass spectrum with the pressure within the mass spectrometer at the operational pressure is output.

Abstract: A method of performing mass spectrometry includes obtaining, based on a series of mass spectra of detected ions derived from components eluting from a chromatography column, a plurality of extracted ion chromatograms (XICs), each XIC comprising a plurality of detection points representing detected intensity for a distinct selected m/z as a function of time; detecting, based on the series of mass spectra, precursor ions of each distinct selected m/z of the plurality of XICs; and determining, for each XIC based on a set of detection points of the XIC, a predicted next detection point to be obtained based on a next mass spectrum to be acquired.

Abstract: Technologies for enhancing performance of a clutch that is installed in connection with a transport climate control system is provided. Enhancing performance of the clutch can be performed by establishing engagement cycling parameters for the clutch, cycling the clutch through a repetition of engagement and disengagement in accordance with the established engagement cycling parameters, and terminating the cycling upon achievement of at least one predetermined criterion.

Abstract: An interface system for connecting a vehicle and a transport climate control system (TCCS) is disclosed. The interface system includes a two-way communication interface that connects a vehicle electrical system (VES) controller and a TCCS controller. The interface system also includes a power interface that connects a vehicle energy source of the VES to the TCCS and a TCCS energy source of the TCCS to the VES. The two-way communication interface is configured to distribute a TCCS status from the TCCS controller to the VES controller, and is configured to distribute a VES status from the VES controller to the TCCS controller. The power interface is configured to distribute power from the vehicle energy source to the TCCS when a VES instruction is received, and distribute power from the TCCS energy source to the VES when a TCCS instruction is received.

Abstract: A personal radiation and density meter system includes a housing, a radiation detection subsystem and a radiation emitting sub-system. The housing includes an interior portion configured as an interior space, and a slot. The radiation detection sub-system includes a personal radiation dosimeter positioned in the slot. The radiation emitting sub-system includes a shield assembly, a source, an actuator, a trigger, and an aperture.

Abstract: An ion mobility analyser comprising an ion guide is provided. The ion guide defines an ion drift channel extending in an axial direction an includes first and second electrode assemblies provided on opposing sides of the ion drift channel. Each of the first and second electrode assemblies extend in the axial direction and in a transverse direction which is transverse to the axial direction. The first and second electrode assemblies are spaced apart on opposing sides of the ion drift channel by a first distance at a narrowest point along the axial direction. Each of the first and second electrode assemblies comprises a set of first electrodes, and a set of second electrodes. The electrodes in the first and second sets are arranged in an alternating pattern in the transverse direction. The alternating pattern extends in the transverse direction a second distance that is greater than the first distance.

Abstract: A component of an ion optical device is manufactured. The component comprises aligned first and second electrode sets. A first material is machined to provide a part-machined first electrode set that comprises the first electrode set attached to a frame part of the first material. A second material is machined to provide a part-machined second electrode set that comprises the second electrode set attached to a frame part of the second material. The component of the ion optical device is assembled by aligning the part-machined first and second electrode sets. Subsequent to aligning the part-machined first and second electrode sets, the part-machined first electrode set is further machined to separate the first electrode set from the frame part of the first material and the part-machined second electrode set is further machined to separate the second electrode set from the frame part of the second material.

Abstract: A voltage supply for a mass analyser is provided. The voltage supply comprises a voltage source, a first voltage output, a second voltage output, and a voltage divider network. The first voltage output is configured to provide a first voltage to a first electrode of the mass analyser, wherein the first electrode of the mass analyser has a first mass shift per volt perturbation. The second voltage output is configured to provide a second voltage to a second electrode of the mass analyser, wherein the second electrode of the mass analyser has a second mass shift per volt perturbation. The second mass shift per volt perturbation opposes the first mass shift per volt perturbation. The voltage divider network comprises a first resistor and a second resistor.

Abstract: A transport climate control system for providing climate control to a climate controlled space of a transport unit. The transport climate control circuit includes a compressor, an evaporator and at least two fans. The transport climate control circuit also includes a controller for controlling the transport climate control circuit and for defrosting the evaporator coil. When a defrost event is triggered, the controller instructs the transport climate control circuit to supply heat to or around one section of the evaporator coil, and independently controls each of the at least two fans to move the air around the evaporator coil in a controlled direction so that heat from the one section of the evaporator coil is used to convectively heat the inlet of the evaporator coil.

Abstract: A measurement system configured to examine a sample. The system comprises an internally reflective element, a contact member, an actuator, an optical assembly, a sensor, and a controller. The contact member and the reflective element are configured to apply a force to the sample. The optical assembly is configured to scan the sample. Whereby prior to the scan, an initial force is applied to the sample, and after the scan, a resulting force is applied to the sample. The sensor is configured to detect the resulting force applied to the sample, and the controller is configured to receive a signal from the sensor indicative of the detected resulting force. The controller is further configured to control the actuator to adjust the force applied to the sample by the contact member and the internally reflective element from the resulting force to the initial force.

Abstract: The present invention relates to the latching closed of doors on appliances. In particular, the present invention provides an advantageous apparatus for locking the lid of a centrifuge. Apparatus for locking an appliance door in a closed position, the apparatus comprises: a locking member for attachment to a door, the locking member having an engagement section; a locking bolt for engaging the engagement section in the locking member; a linear actuator for moving the locking bolt along an axis, wherein the linear actuator is self-locking.

Abstract: Apparatuses for trapping ions comprise an array of electrodes extending along a surface and one or more further electrodes that are distinct from the array of electrodes. A trapping region for receiving the ions is defined by the array of electrodes and the one or more further electrodes. A control circuit is configured to apply a set of oscillatory voltages to the array of electrodes to repel the ions, wherein each electrode in the array has a different phase to each adjacent electrode. A trapping voltage is applied to at least one of the one or more further electrodes to force the ions towards the array of electrodes, the set of oscillatory voltages and the trapping voltage thereby trapping the ions within the trapping region, wherein the trapping voltage is a time-varying direct current, DC, voltage that increases in magnitude over time.

Abstract: A cleaning device for cleaning electrodes of an ion optical multipole device comprises at least one substantially longitudinal cleaning section, at least one handling section extending axially from the at least one cleaning section and at least one direction section extending axially from the at least one cleaning section. The at least one cleaning section has a larger cross section than the at least one handling section. The at least one direction section is capable of allowing a longitudinal movement of the cleaning device in a first axial direction and resisting a longitudinal movement of the cleaning device in a second, opposite axial direction.

Abstract: A gas supply system for a flame module of a spectrometer and a method of controlling a flame module. The gas supply system comprises an oxidant gas supply line for providing a supply of oxidant gas, an oxidant gas flow valve for varying a gas flow rate of an oxidant gas in the oxidant gas supply line, an oxidant gas safety controller configured to control the oxidant gas flow valve, a fuel gas supply line for providing a supply of fuel gas, a fuel gas flow valve configured to control a gas flow rate of a fuel gas on the fuel gas supply line, and a fuel gas safety controller configured to control the fuel gas flow valve. During normal operation, the oxidant gas safety controller is configured to charge an energy storage circuit of the oxidant gas safety controller.

Abstract: According to a first aspect there is disclosed an assembly comprising a power device and a cooling plate which overlies the power device for heat transfer therebetween. The power device comprises a plurality of power switching components including at least a first power switching component and a second power switching component; wherein each of the power switching components is configured to dissipate heat to the cooling plate.

Abstract: The present disclosure describes oligonucleotide-tethered nucleotides, methods of making them, and methods of using them. The oligonucleotide-tethered nucleotides comprise, in some embodiments, a nucleotide linked to an oligonucleotide of from about 3 to about 100 nucleotides in length. These oligonucleotide-tethered nucleotides can be used to label a plurality of different types of nucleic acids in a plurality of different situations with a known oligonucleotide, which can serve as a barcode in some embodiments. The resulting oligonucleotide-labeled nucleic acids oligo-nucleotides can be used in a variety of nucleic acid sequencing methods.

Abstract: Gas detection devices comprise a dehydration unit a concentration unit, and a temperature control unit for controlling a temperature. The gas detection device includes a sampling mode in which sample gas flows into and out of the dehydration unit through a first port and a second port, respectively, wherein the volatile organic compounds in the sample gas are concentrated in the concentration unit. The temperature control unit may be configured such that the temperature of the sample gas after flowing out from the dehydration unit and before flowing into the concentration unit is not greater than a first preset temperature. Generation of condensed substances in the sample gas can be effectively avoided in a simple manner after the sample gas flows into the concentration unit, thereby further preventing ice blockage. Methods for detecting volatile organic compounds in a sample gas are also disclosed.

Abstract: A radiation detector is described. The detector includes a silicon photomultiplier, a scintillator, and a layer comprising metal that is spaced from the scintillator. The scintillator is arranged to emit light towards the silicon photomultiplier. The layer comprising metal is configured to receive incident light radiation and to provide additional radiation to the scintillator in response to the received incident radiation. A method of forming such a radiation detector is also described.