Abstract: A method of analysing labelled analyte ions comprises fragmenting labelled analyte ions to produce analyte fragment ions and reporter ions or complementary ions, analysing the analyte fragment ions using a time-of-flight mass analyser operating in a first mode of operation, and analysing the reporter ions or the complementary ions using the time-of-flight mass analyser operating in a second mode of operation. In the first mode of operation, ions are caused to travel along a flight path having a first length, and in the second mode of operation, ions are caused to travel along a flight path having a second length, wherein the second length is greater than the first length.

Abstract: A fuel delivery system for controlling an inlet pressure of a prime mover in a transport climate control system is provided. The fuel delivery system includes a fuel tank, a pressure regulator, a pump disposed downstream of the fuel tank, a first filter disposed downstream of the pump, and the prime mover disposed downstream of the first filter. The prime mover is located above the fuel tank in a vertical direction. The pump is configured to provide a first fuel flow through the first filter. The prime mover is configured to accept a first portion of the first fuel flow and is configured to provide a return fuel flow. The pressure regulator is disposed downstream of the first filter. The pressure regulator is configured to accept a second portion of the first fuel flow, and to accept a pressure of the return fuel flow as a reference pressure.

Abstract: A bracket for a power module of a transport refrigeration unit is provided. The bracket includes a body portion including: an opening for receiving a shaft of an electric machine of the power module; a plurality of first mounting holes extending through the body portion and spaced around the opening for connecting the bracket to the electric machine; and a plurality of second mounting holes for connecting the bracket to an engine of the power module.

Abstract: A transport climate control system is disclosed. The system includes a compressor, a motor-generator-rectifier machine, a belt drive connected to the motor-generator-rectifier machine and the compressor, at least one condenser fan, at least one evaporator fan, and a DC to DC converter. The motor-generator-rectifier machine connects to the at least one condenser fan, the at least one evaporator fan, and the DC to DC converter. The motor-generator-rectifier machine includes a motor, a low voltage generator connected to the motor, and a rectifier connected to the low voltage generator. The motor-generator-rectifier machine can provide a first low voltage DC power to the at least one condenser fan, the at least one evaporator fan, and the DC to DC converter. The DC to DC converter can convert the first low voltage DC power to a second low voltage DC power that is different from the first low voltage DC power.

Abstract: Methods are described for the automatic determination and correction of retention time shift of a MS data set relative to a control data set, to correct for retention time drifts endemic to targeted LCMS analyses. In an embodiment, a 2D grid of periodic MS spectra versus time is collected for a control experiment, and RT windows are determined with an additional set of unscheduled mass spectral analyses. During successive experiments, spectra from periodic MS scans are used to determine the correspondence between the current time and the time in the control experiment. The active set of MSn scans to be acquired by the instrument is then determined as the scans with adjusted retention time windows that bracket the corrected retention time.

Abstract: Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.

Abstract: A method for cleaning an electrospray emitter of a mass spectrometer comprises the steps of: (a) changing a mode of operation of the electrospray emitter from a stable jet mode of operation to a dripping mode or a pulsating mode of operation by lowering a magnitude, |V|, of a voltage applied between a counter electrode and the electrospray emitter; and (b) changing the mode of operation of the electrospray emitter from the dripping mode or the pulsating mode of operation to the stable jet mode of operation by increasing the magnitude, |V|, of the applied voltage; wherein the repetitions are performed at a predetermined frequency that depends on one or more of liquid flow rate, an emitter internal diameter, and liquid properties.

Abstract: The present invention relates to a centrifuge rotor with a rotor body and a receptacle arranged centrally therein for receiving a drive head of a drive shaft of a centrifuge which can be rotated about an axis of rotation (R), and sample receptacles for accommodating a plurality of sample containers. A holding crown is arranged on a top side (O) of the rotor body facing away from an insertion side (E) of the drive head, said holding crown having an annular base body, which encloses a central opening, and prongs extending upward away from the top side (O), wherein the holding crown is arranged in such a way that the axis of rotation (R) runs through the central opening. The present invention further relates to a holding crown for use with a centrifuge rotor and having an annular base body enclosing a central opening and prongs emanating from the base body and extending upward, wherein the prongs are offset at least in the region of their free ends by a spacing (A) from an inner edge of the base body.

Abstract: A power distribution unit (PDU) for use with an electrically powered accessory is disclosed. The PDU includes at least one power input configured to receive electrical power from an electrical supply equipment and/or a second power source. The PDU also includes an accessory power interface configured to provide power to the electrically powered accessory. The PDU further includes a vehicle power interface configured to provide power to a vehicle electrical system of the vehicle. Also the PDU includes at least one switch configured to selectively connect the at least one power input to a power bus, and selectively connect the power bus to at least one of the accessory power interface and the vehicle power interface. The PDU also includes a controller configured to control the at least one switch to provide power to the electrically powered accessory and/or the vehicle electrical storage device of the vehicle electrical system.

Abstract: This disclosure relates generally to a prime mover system. More specifically, this disclosure relates to a prime mover exhaust system that can prevent the accumulation of debris (e.g., soot or unburned fuel) in the prime mover system. In accordance with at least one embodiment described and recited herein, a self-cleaning prime mover exhaust system is provided. The prime mover exhaust system includes an exhaust tip, an exhaust pipe, and a cleaning tube. The exhaust tip is configured to eject exhaust out of the prime mover exhaust system, the exhaust pipe is configured to direct the exhaust away from a prime mover, and the cleaning tube is configured to accumulate debris exiting from the exhaust pipe and configured to vacuum the debris out of the self-cleaning prime mover exhaust system through the exhaust tip using the Venturi effect.

Abstract: A condenser fan includes a lock hub and multiple blades that are fastened to the hub. Each of the blades includes six planes, each of which having variable parameters including pitch angle, sickle, chord length, and blade curve. For each embodiment of the evaporator fan, the blades are identically configured.

Abstract: A method of performing mass spectrometry includes accessing a series of mass spectra of detected ions derived from components eluting from a chromatography column; obtaining, based on the series of mass spectra, an elution profile including a plurality of detection points representing intensity of at least a set of the detected ions as a function of time; and determining, based on a set of detection points included in the plurality of detection points, a predicted next detection point of the elution profile to be obtained based on a next mass spectrum to be acquired subsequent to acquisition of the series of mass spectra.

Abstract: A method for compositional analysis includes providing a sample having a surface, moving an ablation point to a plurality of positions on the surface along a fractal path, pulsing an energy source to provide an electromagnetic energy beam to ablate material at the ablation point, collecting an emission spectrum in response to pulsing the energy source, and analyzing the emission spectrum to determine a composition at the surface.

Abstract: A signal processing unit comprises: at least one data signal input line adapted to receive a measured data signal generated by an image current, the measured data signal comprising an added crosstalk signal induced by a source of electromagnetic disturbance; at least one disturbance signal input line adapted to receive a decoupled disturbance signal, extracted from the source of electromagnetic disturbance; an output line adapted to supply a compensated data signal; a conditioning module, to which the decoupled disturbance signal is supplied via the disturbance signal input line and which provides a compensation signal; and an adding module, to which the measured data signal and the compensation signal are provided and in which the measured data signal and the compensation signal are superposed, whereby the decoupled disturbance signal is conditioned by the conditioning module such that the compensation signal essentially corresponds to an inverted added crosstalk signal.

Abstract: A transport climate control system to cost-effectively maintain an ultra-low temperature over an extended period of time is provided. The transport climate control system includes a primary climate control system and a secondary climate control system. The primary climate control system includes a first compressor, a first condenser, a first expander, and a main evaporator that is configured to thermally communicate with a climate controlled space. The secondary climate control system includes an ultra-low temperature phase changing medium packaged inside or outside of an enclosure for a cargo. The secondary climate control system is configured to thermally communicate with the climate controlled space, the primary climate control system, and the cargo to provide additional or backup climate control capacity at the ultra-low temperature.

Abstract: This disclosure relates to thermophilic family B DNA polymerases comprising a neutral amino acid residue at a certain position near the C-terminus of the catalytic domain, which corresponds to a position occupied by a basic amino acid residue in wild-type Pfu polymerase. The thermophilic family B DNA polymerases provided herein also comprise an N-terminal domain comprising a uracil-binding pocket that has been modified to reduce template uracil binding. Related uses, methods, and compositions are also provided. In some embodiments, the polymerases comprise a 3?-5? exonuclease domain and/or a sequence nonspecific dsDNA binding domain.

Abstract: A method for compositional analysis includes providing a sample having a surface and determining with a controller a plurality of equidistant positions along an oscillatory path along the surface. The oscillatory path is sinusoid in at least one orthogonal dimension within a plane approximately parallel to the surface. The method further includes, for each equidistant position of the plurality of equidistant position, moving an ablation point along the oscillatory path to the each equidistant position, pulsing an energy source to provide an electromagnetic energy beam to ablate material at the ablation point, and collecting an emission spectrum with a spectrographic instrument in response to pulsing the energy source. The method also includes analyzing the emission spectrum to determine a composition at the surface.

Abstract: A mass spectrometry method comprises: introducing a first packet of ions into an electrostatic trap mass analyzer through a set of electrostatic lenses, wherein, during the introducing of the first packet, either the lenses are operated in a first mode of operation or an injection voltage of a first pre-determined magnitude is applied to an electrode of the mass analyzer; mass analyzing the first ion packet using the mass analyzer; introducing a second packet of ions into the mass analyzer through the set of lenses, wherein, during the introducing of the second packet, either the lenses are operated in a second mode of operation or an injection voltage of a second pre-determined magnitude is applied to the electrode of the mass analyzer; and mass analyzing the second packet of ions using the electrostatic trap mass analyzer.