Abstract: The present invention relates to an apparatus for isotope ratio mass spectrometry that comprises: a mass spectrometer comprising a sample input and a system for delivery of an analyte and a reference substance to the mass spectrometer.

Abstract: Glycerol-free enzyme formulations are described. In some embodiments, a glycerol-free enzyme formulation is stabilized by high salt concentration. The glycerol free enzyme formulation may comprise a reverse transcriptase enzyme.

Abstract: An optical measurement system measurement system for examining a sample. The measurement system comprises an internally reflective element, a stage, an optical assembly, a chassis, and a sensor. The internally reflective element has a contact surface. The stage is positioned below the internally reflective element. The stage and the internally reflective element are configured to apply a force to the sample. The optical assembly comprises a light source and a light detector. The optical assembly is configured to scan the sample by directing source light from the light source towards the contact surface and detecting source light optically interacting with the contact surface by the light detector. The chassis is configured to support the optical assembly and the internally reflective element. The sensor is mounted to the chassis and configured to detect the force applied to the sample by the internally reflective element and the stage.

Abstract: Systems and methods are provided for providing energy consumption feedback for powering a transport climate control system using external data. This can include determining whether an energy level of an energy storage source is greater than an expected energy consumption of a transport climate control system during a route, based on route parameters and route conditions. The route conditions may be obtained from a source such as a remote server, and include data such as weather data, traffic data, or the like. The systems and methods may further compare current energy levels to an updated predictions of energy consumption during transit to determine if the energy level is sufficient to complete the route and alert the user when the energy level is insufficient to complete the route.

Abstract: Method and system of mass spectrometry is provided. The method comprises performing a first and a second MS1 scans on precursor ions produced by ionising a sample. The first MS1 scan comprises mass analysing a first set of the precursor ions transported to a mass analyser using an ion transport device operated at a first setting. The second MS1 scan comprises mass analysing a second set of the precursor ions transported to a mass analyser using the ion transport device operated at a second setting. Energies imparted on the precursor ions by the ion transport device are different in the first and second settings. Based on intensities of mass spectral peaks of the first and second MS1 scans, a mass spectral peak in at least one of the first MS1 scan or the second MS1 scan indicative of a precursor ion mass spectral peak is determined.

Abstract: An interface ion guide for transmitting ions from a stacked ring ion guide (SRIG) to a multipole ion guide, the interface ion guide having a longitudinal axis and comprising n set(s) of plate electrode(s), wherein n?1; each set of plate electrodes comprising two or more plate electrodes; each plate electrode comprising a plate, the plate comprising a planar surface and an aperture formed in the planar surface for transmission of ions therethrough along the longitudinal axis, wherein the plate of each plate electrode is spaced apart from the plate of an adjacent plate electrode along the longitudinal axis; each plate electrode further comprising one or more protrusions, wherein each protrusion extends at a respective non-zero angle to the planar surface, wherein the protrusion(s) of each set of plate electrodes are configured to generate an RF multipole field to focus ions towards the longitudinal axis.

Abstract: A seal for an overhead door includes a first sidewall, and a second sidewall that extends from the first sidewall. The first and second sidewalls extend beyond a bottom corner of the overhead door to cover an opening formed by compression of an astragal attached to a bottom surface of the overhead door.

Abstract: An ion source includes an electron generator, an ionization chamber, and a magnetic field. The electron generator is configured to produce electrons. The ionization chamber has an electron entrance aperture through a first wall, an ion exit aperture through a second wall, and an axis. The ionization chamber is configured to produce ions. The magnetic field is arranged to confine electrons in a beam directed through the electron entrance aperture, in a direction within 45 degrees of parallel to the axis, and towards a location displaced from the ion exit aperture.

Abstract: An interface system for connecting a vehicle and a transport climate control system (TCCS) is disclosed. The interface system includes a two-way communication interface that connects a vehicle electrical system (VES) controller and a TCCS controller. The interface system also includes a power interface that connects a vehicle energy source of the VES to the TCCS and a TCCS energy source of the TCCS to the VES. The two-way communication interface is configured to distribute a TCCS status from the TCCS controller to the VES controller, and is configured to distribute a VES status from the VES controller to the TCCS controller. The power interface is configured to distribute power from the vehicle energy source to the TCCS when a VES instruction is received, and distribute power from the TCCS energy source to the VES when a TCCS instruction is received.

Abstract: Adjusting compensation voltage (CV) parameters of an ion mobility device is described. In one instance, the CV parameters are adjusted to reflect a different CV range, a number of CV steps, or a CV step size to increase throughput of a mass spectrometer.

Abstract: A method comprises: obtaining, from a series of mass spectra including a most recent mass spectrum and a plurality of previously-acquired mass spectra, an elution profile comprising a plurality of detection points each representing intensity of ions accumulated over an accumulation time and detected by a detector as a function of time; classifying, based on a subset of detection points included in the plurality of detection points, a current signal state of the elution profile; and setting, for a next acquisition of a mass spectrum, the accumulation time based on the classified current signal state of the elution profile.

Abstract: An embodiment of a gas analyzer is described that comprises a light source configured to produce a substantially collimated first beam with a diverging angle of less than about 15 degrees; a gas cell comprising an inlet configured to introduce a gas into the gas cell, an outlet configured to remove the gas from the gas cell, and a plurality of mirrors configured to reflect the substantially collimated first beam within the gas cell; and a detector configured to generate a signal in response to the substantially collimated first beam.

Abstract: The present invention provides an electrode arrangement 10, 10? for an ion trap, ion filter, an ion guide, a reaction cell or an ion analyser. The electrode arrangement 10, 10? comprises an RF electrode 12a, 12b, 12a?, 12b? mechanically coupled to a dielectric material 11. The RF electrode 12a, 12b, 12a?, 12b? is mechanically coupled to the dielectric material 11 by a plurality of separators 13 that are spaced apart and configured to define a gap between the RF electrode 12a, 12b, 12a?, 12b? and the dielectric material 11. Each of the plurality of separators 13 comprises a projecting portion 13b and the dielectric material 11 comprises corresponding receiving portions 11a such that on coupling of the RF electrode 12a, 12b, 12a?, 12b? to the dielectric material 11, the projecting portion 13b of each separator 13 is received within the corresponding receiving portion 11a of the dielectric material 11.

Abstract: Technologies are described herein to prioritize delivery of power to electrical components associated with a vehicle and an electrically powered accessory. A power distribution unit may assess real-time power needs for the electrical storage system associated with the vehicle and electrical storage device of the electrically powered accessory and direct incoming power to the electrical storage system associated with the vehicle and the electrical storage device of the electrically powered accessory based on a prioritization of various factors.

Abstract: Methods and systems for providing feedback for a transport climate control system are disclosed. The transport climate control system provides climate control to a climate controlled space of a transport unit. The method includes determining, by a controller, a first energy level state capable of providing power to the transport climate control system. The method also includes obtaining, by the controller, status data when a predetermined triggering event occurs. The method further includes determining, by the controller, a second energy level state capable of providing power to the transport climate control system after a predetermined time interval. Also the method includes determining energy consumption data based on the first energy level state and the second energy level state. The method further includes combining the status data and the energy consumption data to obtain feedback data. The method also includes displaying, via a display device, the feedback data.

Abstract: A climate control system includes a compressor which includes a compressor housing, a compressor element provided in the compressor housing, a lubricant circuit, and an auxiliary sump. The lubricant circuit includes a lubricant sump provided in the compressor housing. The auxiliary sump is in fluid communication with the lubricant sump. A method for maintaining lubrication supply for a compressor of a climate control system includes transferring lubricant from the auxiliary sump to the lubricant sump of the compressor when a height of the lubricant in the auxiliary sump is greater than a height in the lubricant sump and returning the lubricant from the lubricant sump to the auxiliary sump when a height of the lubricant in the lubricant sump is higher than a height of a predetermined minimum level in the lubricant sump. The lubricant in the auxiliary sump and lubricant sump are equalized by gravity.

Abstract: A method of gain calibration for an ion detector operating at a detector voltage is described. The method includes steps of: generating single ions; determining a parameter of a first relationship between a detector output of an ion detector and a number of ions for a first detector voltage; detecting an ion peak at the ion detector using the first detector voltage; adjusting the detector voltage; and determining a parameter of a second relationship between the detector output and the number of ions for the second detector voltage. A system including a mass spectrometer arrangement and a controller configured to operate the mass spectrometer arrangement in accordance with this method is also described.

Abstract: A temperature-controlled electronic apparatus, comprises: a circuit board; a plurality of electronic components, mounted on the circuit board in an arrangement to form at least one electronic circuit; a temperature sensor, configured to measure a temperature of the at least one electronic circuit; and a heat-generating component, configured to be controlled by a temperature control circuit, the temperature control circuit being configured to control an amount of heat generated by the heat-generating component in response to the temperature measured by the temperature sensor. The plurality of electronic components are arranged on the circuit board to lie on one of one or more paths, each path of the one or more paths being defined by a respective circle having a radius.

Abstract: An ion separation apparatus comprises: (a) first and second ion carpets, each comprising: a substrate having first and second faces; and a set of electrodes disposed on or beneath the first face, wherein a configuration of a first plurality of the set of electrodes defines at least one group of circle sectors; (b) an ion exit aperture passing through one ion carpet; and (c) one or more power supplies configured to provide radio frequency voltages to a first subset of the electrodes of each ion carpet, to provide electrical potential differences across electrodes of the first subset of electrodes of each ion carpet, and to provide time-varying voltages to the first plurality of electrodes of each ion carpet that migrate through the sectors as a traveling wave, wherein the ion carpets are disposed parallel to one another with a gap therebetween, the first faces facing one another across the gap.

Abstract: The present invention relates to a centrifuge, in particular a laboratory centrifuge, comprising a rotor which is rotatably mounted in an interior of a rotor chamber and is designed to accommodate sample vessels, a drive motor to set the rotor in rotation, and a cooling device which is designed to dissipate heat from the interior of the rotor chamber via a coolant, the cooling device being designed to use an elastocaloric effect and having at least one cooling unit which comprises an elastocaloric material arranged between a counter block and a punch, the punch being designed to periodically apply a force to the elastocaloric material and then to let the elastocaloric material relax again, the cooling device being designed to transfer both heat from the elastocaloric material to the coolant and from the coolant to the elastocaloric material. The present invention also relates to a method for cooling an interior of a rotor chamber of such a centrifuge.