Abstract: A synthetic peptide having nestin expression inducing ability which allows induction of expression of nestin in astrocytes; an agent for inducing nestin expression including the peptide as an active ingredient; and a method for producing high nestin expressing cells derived from astrocytes, the method being characterized in that the agent for inducing nestin expression is supplied. The agent for inducing nestin expression provided by the present invention includes, as an active ingredient, a synthetic peptide including a nestin-inducing peptide sequence consisting of an amino acid sequence of SEQ ID NO: 1 or an amino acid sequence formed by conservative replacement of 1, 2 or 3 amino acid residues in the amino acid sequence. The method for producing high nestin expressing cells derived from astrocytes provided by the present invention includes preparing an astrocyte culture, and supplying, at least once, the agent for inducing nestin expression to the astrocyte culture.

Abstract: The present invention provides a method that allows highly efficient and highly reliable evaluation of genomic stability of pluripotent stem cells, a method for removing pluripotent stem cells that have been identified as genomically unstable by the evaluation method from a culture of pluripotent stem cells to be evaluated, and a synthetic peptide that can be used for the methods. The methods provided by the present invention include preparing a culture of pluripotent stem cells of interest and analyzing an expression level of calreticulin for the pluripotent stem cells in the culture followed by identifying genomic stability or genomic instability of the stem cells on the basis of the expression level of calreticulin.

Abstract: A deodorizing mask includes an air permeable mask main body for covering nose and mouth of the user with at least two types of nonwoven cloth, the mask main body having a deodorizing nonwoven cloth layer including a chemical adsorptive deodorizer and a dustproof nonwoven cloth layer having a dustproof effect, and the air permeability of the dustproof nonwoven cloth layer being ? or less of the air permeability of the deodorizing nonwoven cloth layer. Preferably, the air permeability of the dustproof nonwoven cloth layer is in a range of 10 to 120 cm/(cm·s) in a permeated air quantity based on the Frazir method, the air permeability of the deodorizing nonwoven cloth layer is in a range of 40 to 400 cm/(cm·s) in a permeated air quantity based on the Frazir method, and the permeated air quantity of the dustproof nonwoven cloth layer is ? or less of the permeated air quantity of the deodorizing nonwoven cloth layer.

Abstract: The flame-retardant adhesive composition contains a styrene-based elastomer containing a carboxyl group, an epoxy resin, and a phosphorus-containing oligomer including a structural unit represented by general formula (1), and the epoxy resin content is 1-20 parts by mass and the phosphorus-containing oligomer content is 10-50 parts by mass with respect to 100 parts by mass of the styrene-based elastomer containing carboxyl groups. (wherein, R1 and R2 are each independently a hydrogen atom or a methyl group, n is an integer of 1-20.

Abstract: A curing-type coating-agent composition according to the present invention contains: Component (A) (e.g., an isocyanuric ring-containing urethane (meth)acrylate compound) in an amount of from 20 to 80 parts by mass; Component (B) (e.g., an isocyanuric ring-containing tri(meth)acrylate compound free from any urethane bond) in an amount of from 10 to 70 parts by mass; Component (C-1) (e.g., a reaction compound between a colloidal silica and an alkoxysilane compound having a maleimide group) in amount of from 1 to 35 parts by mass, or Component (C-2) (e.g., a specific organosilicon compound) in an amount of from 5 to 35 parts by mass; a radical-polymerization initiator serving as Component (D) in an amount of from 0.

Abstract: Provided is a curable resin composition which exhibits excellent curability and is good in storage stability. The curable resin composition comprises (a) a polymer having a hydrolyzable silyl group, (b) an acid catalyst, and (c) an onium salt represented by the following general formula (1): C+A???(1) wherein C+ is an onium cation, and A? is a hydrogen sulfate anion, a hydrogen sulfite anion, a sulfonate anion represented by R1SO3? wherein R1 represents an alkyl group, perfluoroalkyl group, cycloalkyl group, vinyl group, aryl group, perfluoroaryl group, aralkyl group or halogen atom; or a bis(substituted sulfonyl)imide anion represented by (R2SO2)2N? wherein R2 represents an alkyl group, perfluoroalkyl group, or aryl group; tetrafluoroborate anion, or hexafluorophosphate anion.

Abstract: The thermosetting composition of the present invention comprises 100 parts by mass of an organosilicon compound represented by a general formula (1) and 0.01 to 10 parts by mass of a polymerization initiator having a 10-hour half-life temperature in a range from 80° C. to 130° C. (In the formula (1), R1, R2, R3, R4 and R5 are each, independently, a hydrogen atom, an alkyl group having 1 to 10 carbon atoms, an aralkyl group having 7 to 10 carbon atoms, a cycloalkyl group having 1 to 10 carbon atoms, a cycloaralkyl group having 9 to 12 carbon atoms, an aryl group having 6 to 10 carbon atoms or a group having an ethylenically unsaturated group; at least one of R1, R2, R3, R4 and R5 is a group having an ethylenically unsaturated group; R6 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; v, w, x, y and z represent number of moles and are 0 or a positive number; at least one of w and x is a positive number; 0?w/(v+x+y+z)?10 is satisfied.

Abstract: A composition including an artificially synthesized antimicrobial peptide that is not present as a mature peptide in nature. The composition includes an artificially synthesized peptide that has an antimicrobial activity against at least one strain of bacteria or fungi and includes an amino acid sequence represented by any one of SEQ ID NOs: 1 to 6 or an amino acid sequence formed by substituting, deleting and/or adding one, two or three amino acid residues in/from/to the amino acid sequence, and further including at least one species of pharmaceutically acceptable carrier.

Abstract: This invention provides a TNFR2 expression-inducing composition including as an active ingredient a peptide having TNFR2 expression-inducing activity, and a method for producing cells that express TNFR2 selectively by use of the composition. The cell production method provided by this invention includes: culturing at least one species of cells capable of expressing TNF receptor 2, and supplying the cells with a synthetic peptide consisting of a nuclear localization signal sequence (NLS) or a nucleolar localization signal sequence (NoLS) to enhance TNFR2 expression in the cells.

Abstract: This invention provides a multipolar cell including three or more centrosomes dispersed therein and a multipolar spindle formed so as to extend from the three or more respective centrosomes. The multipolar cell production method provided by the present invention supplies cultured eukaryotic cells with a synthetic peptide as a multipolarity-inducing peptide, with the synthetic peptide having an amino acid sequence selected from SEQ ID NO: 1 to SEQ ID NO: 12 or an amino acid sequence formed by substituting, deleting and/or adding one, two or three amino acid residues in/from/to the selected amino acid sequence.

Abstract: A 2-cyanoacrylate-based adhesive composition includes a 2-cyanoacrylic acid ester (a) and an onium salt (b) represented by general formula C+A?. In the formula, C+ is an onium cation, and A? is a hydrogen sulfate anion, bisulfite anion, sulfonate anion represented by R1SO3? (where R1 is an alkyl group, perfluoroalkyl group having 3 to 10 carbon atoms, cycloalkyl group, vinyl group, aryl group, perfluoroaryl group, aralkyl group, or halogen atom), or bis(substituted sulfonyl)imide anion represented by (R2SO2)2N? (where R2 is an alkyl group, perfluoroalkyl group, or aryl group).) The 2-cyanoacrylate-based adhesive composition has good storage stability and has an excellent adhesion rate to metals and thermoplastic elastomers.

Abstract: This invention provides a multipolar cell including three or more centrosomes dispersed therein and a multipolar spindle formed so as to extend from the three or more respective centrosomes. The multipolar cell production method provided by the present invention supplies cultured eukaryotic cells with a synthetic peptide as a multipolarity-inducing peptide, with the synthetic peptide having an amino acid sequence selected from SEQ ID NO: 1 to SEQ ID NO: 10 or an amino acid sequence formed by substituting, deleting and/or adding one, two or three amino acid residues in/from/to the selected amino acid sequence. As the eukaryotic cells, cultured tumor cells are used.

Abstract: This invention provides a silicon wafer polishing composition used in the presence of an abrasive. The composition comprises a silicon wafer polishing accelerator, an amide group-containing polymer, and water. The amide group-containing polymer has a building unit A in its main chain. The building unit A comprises a main chain carbon atom constituting the main chain of the amide group-containing polymer and a secondary amide group or a tertiary amide group. The carbonyl carbon atom constituting the secondary amide group or tertiary amide group is directly coupled to the main chain carbon atom.

Abstract: There is provided a method of production of chlorine.sodium hydroxide capable of being operated stably and economically by preventing calcium from being deposited in an ion exchange membrane. The liquid retention layer 3 having a liquid retention amount per unit volume of the liquid retention layer of 0.10 g-H2O/cm3 or more and 0.80 g-H2O/cm3 or less is put between the ion exchange membrane 12 and the gas diffusion electrode 16. Calcium ions transferred through the ion exchange membrane 12 easily diffuse, thereby making it possible to suppress increase in an electrolytic voltage and drop in current efficiency generated by deposition of the calcium ions inside the ion exchange membrane 12.

Abstract: Provided is an adhesive composition leading to sufficient adhesive strength when used for bonding to a polyolefin resin molded article that bonds poorly with other members. Also provided is an adhesive composition having excellent heat resistance (heat resistant adhesion) in the bonded part of a composite body obtained by joining a polyolefin resin-formed body and other member. This adhesive composition contains an organic solvent, a carboxyl group-containing polyolefin resin which is dissolved in this organic solvent and which has a melt flow rate of 5 to 40 g/10 min when measured at 130° C., and a polyfunctional isocyanate compound. This adhesive composition may further contain a carboxyl group-containing polyolefin resin having a melting point of 120° C. to 170° C.

Abstract: An advantage of some aspects of the invention is to provide an antibody against an amyloid precursor protein signal peptide. The invention provides an amyloid precursor protein signal peptide.

Abstract: To provide a method for producing an aldehyde gas deodorant which has high aldehyde deodorizing performance, and which is negative for mutagenicity and excellent in safety, and a deodorant processed product. A method for producing an aldehyde gas deodorant, the method comprises the steps of: preparing a deodorizing composition containing a dihydrazide compound, a water-containing inorganic powder, and water; and heating the deodorizing composition at a temperature of from 45° C. to 90° C. so that water remains in an amount of 4.5% by mass or more, based on the total mass of the deodorant produced, and wherein the aldehyde gas deodorant is negative for mutagenicity measured by an AMES test.

Abstract: This invention provides an antitumor peptide and an antitumor composition that includes the peptide for suppressing proliferation of at least one species of tumor cells. The antitumor composition provided by this invention includes an antitumor peptide capable of inducing formation of multipolar spindles in at least one species of tumor cells, and at least one species of pharmaceutically acceptable carrier, wherein the antitumor peptide is a synthetic peptide having an amino acid sequence selected from SEQ ID NOs: 1 to 22 or an amino acid sequence formed by substituting, deleting and/or adding one, two or three amino acid residues in/from/to the selected amino acid sequence.

Abstract: An inorganic ion adsorbent represents by Formula (1) below, wherein in powder X-ray diffraction measurement using CuK? radiation, the diffraction intensity of tetragonal tin oxide is at least 3% relative to the diffraction intensity of antimony pentoxide (Sb2O5.2H2O), and the diffraction intensity of cubic antimony pentoxide is no greater than 40% relative to the diffraction intensity of antimony pentoxide (Sb2O5.2H2O), SnO2.aSb2O5.nH2O??(1) wherein in the Formula, a denotes a number that satisfies 0.2?a?4 and n denotes hydration number and is 0 or a positive number.

Abstract: An adhesive composition for medical use of the present invention includes an acrylic copolymer, a medicament having a carboxyl group, and a base, the acrylic copolymer is prepared by copolymerization of a monomer mixture containing 0.1 to 2 mass % of an ethylenically unsaturated carboxylic acid monomer as a monomer A, 58 to 99.9 mass % of an alkyl(meth)acrylate ester having an alkyl group of 4 to 12 carbon atoms as a monomer B, 30 mass % or less of an alkyl(meth)acrylate ester having 1 to 3 carbon atoms as a monomer C, and 30 mass % or less of a monomer having an ethylenically unsaturated group other than those of the monomers A to C (the total of monomers A to D is taken as 100 mass %) as a monomer D, and the content of sulfuric acid in the acrylic copolymer is 700 ppm by mass or less.