Patents Assigned to Tohoku University
  • Publication number: 20220201832
    Abstract: A flow control method is a flow control method of controlling flow around a blade of a rotary wing, a plasma actuator being disposed at the blade. The flow control method includes: determining a characteristic frequency ratio that is a characteristic value among frequency ratios, each of the frequency ratios being a ratio between an actuator driving frequency and an angle of attack changing frequency, the actuator driving frequency being a frequency of an applied voltage applied to the plasma actuator, the angle of attack changing frequency being a frequency at which an angle of attack of the blade changes in accordance with a rotation angle of the blade; setting the actuator driving frequency such that the frequency ratio becomes the characteristic frequency ratio; and applying a voltage of the set actuator driving frequency to the plasma actuator to control the flow around the blade.
    Type: Application
    Filed: April 2, 2020
    Publication date: June 23, 2022
    Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, TOHOKU UNIVERSITY
    Inventors: Hidemasa YASUDA, Akio OCHI, Kenji HAYAMA, Tomoka TSUJIUCHI, Kazuyuki NAKAKITA, Taku NONOMURA, Atsushi KOMURO, Keisuke TAKASHIMA
  • Publication number: 20220198891
    Abstract: A vibration control apparatus configured to control a vibration generated by a vibration apparatus, using a signal, includes processer circuitry, and an energy controller configured to convert a waveform of the signal while maintaining energy of the signal.
    Type: Application
    Filed: March 9, 2022
    Publication date: June 23, 2022
    Applicant: TOHOKU UNIVERSITY
    Inventors: Masashi KONYO, Kosuke YAMAGUCHI, Nan CAO, Satoshi TADOKORO
  • Publication number: 20220199569
    Abstract: A bonded structure includes a first substrate; a second substrate placed opposite to the first substrate; an intermediate layer provided between the first substrate and the second substrate and including a first oxide thin film layered on the first substrate and a second oxide thin film layered on the second substrate; either or both of the first oxide thin film and the second oxide thin film of the intermediate layer being formed of oxide thin films having increased defects; and an interface between the first oxide thin film and the second oxide thin film=being bonded by chemical bonding, and the interface comprising a low-density portion whose density is lower than that of the two oxide thin films.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 23, 2022
    Applicants: TOHOKU UNIVERSITY, CANON ANELVA CORPORATION
    Inventors: Takehito SHIMATSU, Miyuki UOMOTO, Kazuo MIYAMOTO, Yoshikazu MIYAMOTO, Nobuhiko KATOH, Takayuki MORIWAKI, Takayuki SAITOH
  • Publication number: 20220190461
    Abstract: A three-dimensional isotropic metamaterial including an aggregate of SRR-buried block pieces obtained by burying SRRs in a transparent resin cube, at random in a transparent resin member; a method of producing the same; and a terahertz region optical element.
    Type: Application
    Filed: March 27, 2019
    Publication date: June 16, 2022
    Applicant: TOHOKU UNIVERSITY
    Inventors: Yoshiaki KANAMORI, Kazuhiro HANE
  • Patent number: 11359017
    Abstract: The present invention provides a novel method of obtaining data for predicting the onset of an adverse event due to administration of at least one antibody drug selected from an anti-PD-1 antibody, an anti-PD-L1 antibody, an anti-CTLA4 antibody, and an antigen-binding fragment thereof, or a novel method of predicting the onset of the adverse event. More specifically, the present invention provides a method of obtaining data for predicting the onset of an adverse event or a method of predicting the onset of the adverse event, comprising measuring a level of at least one marker selected from sCD163 and CXCL5 in a biological sample collected from a subject administered the antibody drug.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: June 14, 2022
    Assignee: TOHOKU UNIVERSITY
    Inventor: Taku Fujimura
  • Publication number: 20220170106
    Abstract: In order to elucidate the mechanism of malignant alteration of pancreatic cancer caused by BACH1, changes in the gene expression depending on the expression level of BACH1 in the pancreatic cancer cell line were clarified by RNA sequencing. As a result of experiments on in vitro migration ability and invasion ability and in vivo orthotopic transplantation, BACH1 was found to be used as an excellent biomarker for epithelial-to-mesenchymal transition of pancreatic cancer when used alone or in combination with its downstream regulator FOXA1.
    Type: Application
    Filed: February 22, 2019
    Publication date: June 2, 2022
    Applicant: TOHOKU UNIVERSITY
    Inventors: Kazuhiko IGARASHI, Mitsuyo MATSUMOTO, Masaki SATO, Hironari NISHIZAWA
  • Patent number: 11343458
    Abstract: A light-receiving device that achieves both high saturation performance and high sensitivity performance includes a light-receiving pixel including a light-receiving element, a first capacitive element that accumulates a photoelectric charge produced by light received by the light-receiving element, a second capacitive element that accumulates a transferred portion of an amount of the photoelectric charge accumulated in the capacitive element, a switch means for turning on and off a photoelectric charge transfer operation from the capacitive element to the capacitive element, a resetting switch means for resetting the capacitive element and the capacitive element, a pixel selecting switch means, and a source follower switch means. An effective saturation capacity of the capacitive element is 10 to 5,000 times an effective saturation capacity of the capacitive element.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: May 24, 2022
    Assignee: TOHOKU UNIVERSITY
    Inventors: Shigetoshi Sugawa, Rihito Kuroda
  • Publication number: 20220157770
    Abstract: The present invention achieves chemical bonding by means of a joined film made of oxides formed on a joined surface. In a vacuum container, amorphous oxide thin films are respectively formed on smooth surfaces of two substrates, and the two substrates overlap such that the amorphous oxide thin films formed on the two substrates come into contact with each other, thereby causing chemical bonding involving an atomic diffusion at a joined interface between the amorphous oxide thin films to join the two substrates.
    Type: Application
    Filed: February 4, 2022
    Publication date: May 19, 2022
    Applicants: TOHOKU UNIVERSITY, CANON ANELVA CORPORATION
    Inventors: Takehito SHIMATSU, Miyuki UOMOTO, Kazuo MIYAMOTO, Yoshikazu MIYAMOTO, Nobuhiko KATOH, Takayuki MORIWAKI, Takayuki SAITOH
  • Publication number: 20220157361
    Abstract: The present invention provides a device with low power and high performance, which can be applied to sensor nodes, a sensor node using the same, an access controller, a data transfer method, and execute a processing method in a microcontroller. The device has: an MRAM; a non-volatile CPU configured to include a nonvolatile memory; a non-volatile FPGA-ACC configured to include a nonvolatile memory and execute a part of operations on the nonvolatile CPU; and a power-gating control unit that controls power supply to each memory cell in the MRAM, the non-volatile CPU, and the non-volatile FPGA-ACC. The device is further provided with an access controller that controls accesses to the MRAM by reading data in advance and backing up the data when data is to be read from the MRAM.
    Type: Application
    Filed: February 15, 2020
    Publication date: May 19, 2022
    Applicant: TOHOKU UNIVERSITY
    Inventors: Masanori Natsui, Daisuke Suzuki, Akira Tamakoshi, Takahiro Hanyu, Tetsuo Endoh, Hideo Ohno
  • Publication number: 20220145255
    Abstract: Provided is a method of producing an osteoblast construct from iPS cells, the method including the steps of: (1) inducing formation of an embryoid body by subjecting undifferentiated iPS cells to non-adherent culture; (2) inducing differentiation of the iPS cells into mesodermal cells by subjecting the embryoid body of the iPS cells obtained in the step (1) to non-adherent culture; and (3) inducing differentiation into osteoblasts by subjecting the mesodermal cells of the iPS cells obtained in the step (2) to non-adherent culture, wherein the steps (1) and (2) are each performed using a culture vessel comprising a bottom surface and a circular side wall arranged upright on the bottom surface, the bottom surface having a plurality of depressed portions arranged independently of each other.
    Type: Application
    Filed: February 26, 2020
    Publication date: May 12, 2022
    Applicant: TOHOKU UNIVERSITY
    Inventors: Hiroshi EGUSA, Hiroko OKAWA, Naohiro HORIE, Takeru KONDO
  • Patent number: 11326262
    Abstract: A hydrogel is formed by a reaction which is induced, in an electrolytic solution, by an electrode product electrochemically generated by electrodes installed in the electrolytic solution. An apparatus including an electrolytic tank with a bottom surface on which a two-dimensional array of working electrodes is provided and a counter electrode installed in the electrolytic tank is prepared. An electrolytic solution containing a dissolved substance that causes electrolytic deposition of a hydrogel is housed in the electrolytic tank. By applying a predetermined voltage to one or more selected working electrodes of the two-dimensional array, a hydrogel with a two-dimensional pattern corresponding to the arrangement of the selected working electrodes is formed.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: May 10, 2022
    Assignees: TOHOKU UNIVERSITY, JAPAN AVIATION ELECTRONICS INDUSTRY, LIMITED
    Inventors: Kosuke Ino, Tomokazu Matsue, Hitoshi Shiku, Mayuko Terauchi, Noriko Taira, Ryota Kunikata, Atsushi Suda
  • Patent number: 11329819
    Abstract: An information processing system 100 comprising at least one first node 1, second nodes 2 for providing a public key change assistance service, and a blockchain 3, wherein the first node 1 comprises a new public key creation unit 151, a second node group selection unit 152, an old and new key information request unit 153, a draft contract preparation unit 154, a signature request unit 155, a first signature execution unit 156, and a registration unit 157; each second node 2 comprises an old and new key information transmission unit 251, a second signature execution unit 252, and a draft contract return unit 253; the draft contract preparation unit 154 randomly determines the order of new public keys as transmission destinations; and the signature request unit 155 and the first signature execution unit 156 perform signature request and execution, respectively, so that the order of the nodes that sign a draft transaction contract is random.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: May 10, 2022
    Assignee: TOHOKU UNIVERSITY
    Inventors: Masao Sakai, Junya Iwazaki, Eisuke Koizumi, Shingo Hasegawa, Shuji Isobe, Masayuki Fukumitsu
  • Patent number: 11325961
    Abstract: To provide a therapy and a diagnosis of cancer or an infection using recognition mechanism of a T-cell receptor.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: May 10, 2022
    Assignee: TOHOKU UNIVERSITY
    Inventor: Koetsu Ogasawara
  • Patent number: 11326433
    Abstract: A fracturing method, to cause a crack in bedrock, includes installing a depressurizing device in a well in the bedrock, and depressurizing the inside of the well with the installed depressurizing device. The installing step includes installing, in the well, a connecting pipe, which is connected to the depressurizing device, and a packer, which is attached to the connecting pipe, and the depressurizing step includes shutting off a gap between the well and the connecting pipe, with the packer, and depressurizing a region in the well below the packer, with the depressurizing device.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: May 10, 2022
    Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, JMC GEOTHERMAL ENGINEERING CO., LTD., INPEX DRILLING CO., LTD.
    Inventors: Hiroshi Asanuma, Shigemi Naganawa, Noriyoshi Tsuchiya, Tatsuya Kajiwara, Kuniaki Shimada
  • Publication number: 20220140174
    Abstract: A display device includes a substrate including a first surface, and a second surface positioned at a side opposite to the first surface; a first light-emitting element located at a lateral side of the substrate; a plurality of light-receiving elements located at a second surface side of the substrate; a plurality of second light-emitting elements located on the first surface of the substrate; and a first drive element controlling driving of the second light-emitting elements based on output of the light-receiving elements. A light-emitting surface of the first light-emitting element is oriented in a first direction. The first direction is parallel to a direction from the first surface toward the second surface. Light-emitting surfaces of the second light-emitting elements are oriented in a second direction. The second direction is from the second surface toward the first surface.
    Type: Application
    Filed: October 28, 2021
    Publication date: May 5, 2022
    Applicants: TOHOKU UNIVERSITY, NICHIA CORPORATION
    Inventors: Tetsu TANAKA, Takafumi FUKUSHIMA, Hisashi KINO, Masatsugu ICHIKAWA
  • Patent number: 11322221
    Abstract: A memory device includes: a memory cell capable of holding data; and an ECC circuit capable of generating a correction code and detecting an error based on the correction code. The memory cell is accessed by a pipeline operation. The pipeline operation includes at least four pipeline stages including a read cycle reading data from the memory cell, an ECC cycle executing generation of the correction code or error detection for the memory cell in the ECC circuit, a wait cycle during which processing for data related to the memory cell is not executed, and a write cycle writing data into the memory cell.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: May 3, 2022
    Assignees: Sharp Semiconductor Innovation Corporation, TOHOKU UNIVERSITY
    Inventors: Shigeo Ohyama, Tetsuo Endoh
  • Publication number: 20220127698
    Abstract: A titanium alloy additive manufacturing product contains 5.50 to 6.75 wt % of Al, 3.50 to 4.50 wt % of V, 0.20 wt % or less of 0, 0.40 wt % or less of Fe, 0.015 wt % or less of H, 0.08 wt % or less of C, 0.05 wt % or less of N, and inevitable impurities, in which a pore content is 0.05 number/mm2 or less, and a tensile strength is 855 MPa or more.
    Type: Application
    Filed: January 31, 2020
    Publication date: April 28, 2022
    Applicants: TOHOKU UNIVERSITY, JAMPT CORPORATION
    Inventors: Akihiko CHIBA, Noritaka YASUDA
  • Patent number: 11313861
    Abstract: An object of the disclosure is to provide a composition for evaluating the hepatic glucose uptake capacity of a subject and a method for evaluating the hepatic glucose uptake capacity of a subject with the composition. An object of the disclosure is to provide a method for determining the stage of pre-onset diabetes in a subject with pre-onset diabetes using the method for evaluating the hepatic glucose uptake capacity. An aspect of the disclosure accordingly provides a composition comprising 13C-labeled glucose for evaluating the hepatic glucose uptake capacity of a subject. Another aspect of the disclosure provides a method comprising measuring 13C-labeled glucose in a blood sample or an expired air sample obtained from the subject to which the composition was administered. The desired evaluation or determination can be achieved by comparing the measured value with a reference value.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: April 26, 2022
    Assignees: OTSUKA PHARMACEUTICAL CO., LTD., TOHOKU UNIVERSITY
    Inventors: Makoto Inada, Keiko Kawata, Kimiyoshi Sudoh, Hideki Katagiri, Tetsuya Yamada, Kei Takahashi
  • Publication number: 20220122635
    Abstract: Provided is a perpendicular magnetic recording medium that exhibits improved thermal stability and achieves reduction in switching magnetic field by providing a cap layer having characteristics (characteristics contributing to reducing switching magnetic field of the perpendicular magnetic recording medium as well as to improving thermal stability thereof) superior to existing cap layers. A perpendicular magnetic recording layer (24) has a granular structure which comprises Co- Pt-alloy magnetic crystal grains (24A) and a non-magnetic grain boundary oxide (24B). A cap layer (26) has a granular structure which comprises Co-Pt-alloy magnetic crystal grains (26A) and a magnetic grain boundary oxide (26B). The Co- Pt -alloy magnetic crystal grains (26A) in the cap layer (26) contain 65-90 at % of Co and 10-35 at % of Pt. The magnetic grain boundary oxide (26B) is included in a volume fraction of 5-40 vol % with respect to the total volume of the cap layer (26).
    Type: Application
    Filed: December 23, 2019
    Publication date: April 21, 2022
    Applicants: TANAKA KIKINZOKU KOGYO K.K., TOHOKU UNIVERSITY
    Inventors: Kim Kong THAM, Tomonari KAMADA, Ryousuke KUSHIBIKI, Shin SAITO
  • Publication number: 20220117724
    Abstract: This disclosure provides a method of absorbing or discharging water of an ophthalmic medical device capable of absorbing and discharging water, and an ophthalmic medical device. The method of absorbing or discharging water of an ophthalmic medical device of the present disclosure includes using an ophthalmic medical device including a plurality of electrodes, and generating an electroosmotic flow inside and/or outside the medical device.
    Type: Application
    Filed: March 4, 2019
    Publication date: April 21, 2022
    Applicant: TOHOKU UNIVERSITY
    Inventors: Matsuhiko NISHIZAWA, Shotaro YOSHIDA, Shinya KUSAMA