Abstract: A pressure container for crystal production having excellent corrosion-resistance is provided. This pressure container produces crystals within the container using a seed crystal, a mineralizer, a raw material, and ammonia in a supercritical state or a subcritical state as a solvent. The pressure container has Ag present over the entire surface of at least the inner surface thereof in contact with the solvent. The Ag can be disposed by one or a combination of two or more among, for instance, Ag lining, Ag welding, and Ag plating. The mineralizer is preferably a fluorine mineralizer containing no halogen atoms other than fluorine.

Abstract: In order to enable the measurement of thermal property information about a subject, this thermal diffusion coefficient measuring device, which is used by contacting the surface of a living body, is provided with: a biological information sensor comprising a temperature sensor and a heat flux sensor; and a heating/cooling control means. The temperature sensor is provided at a position contacting the surface of the living body, and operates so as to detect skin temperature. The heat flux sensor is provided at a position contacting the surface of the living body, while being adjacent to the temperature sensor, and operates so as to detect heat flux on the surface of the living body. The heating/cooling control means enables the measurement of the temperature diffusion coefficient of a thermal resistance component that is present between the biological information sensor and a deep inner portion of the living body.

Abstract: Amyotrophic lateral sclerosis (ALS) is a life-threatening neurodegenerative disease characterized by the progressive loss of motor neurons. Muse cells are endogenous reparative pluripotent-like stem cells distributed to various tissues. Once intravenously injected, such cells, upon sensing sphingosine-1-phosphate produced by damaged cells, settle selectively on damaged sites, and after homing, can exhibit multiphase effects including natural differentiation into tissue-protecting and tissue-reconstructing cells. In the present invention, with G93A-Tg mice serving as an ALS model, human Muse cells injected intravenously successfully homed into the lumbar cord, mainly at the pia mater and the lower white matter, and expressed glial-like forms and GFAP. Meanwhile, no such homing or differentiation was observed in the case of human mesenchymal stem cells (MSCs), and, rather, MSCs were found distributed to the lungs.

Abstract: An electrostatic acoustic wave generating device and an electrostatic speaker making entries of dust, water, moisture, etc. into the device and the speaker, allowing reduction in power. A plate-like fixed electrode has a through hole penetrating the thickness of the fixed electrode. A vibrating body and a vibrating electrode each having a plate-like shape are arranged closer to one surface and closer to the other surface of the fixed electrode respectively, and are movable in the respective thickness directions thereof. A connection member connects the vibrating body and the vibrating electrode to each other through the through hole of the fixed electrode to cause the vibrating body and the vibrating electrode to move toward the same direction. Voice signal input is capable of applying a voltage to the fixed electrode, the vibrating body, and the vibrating electrode to move the vibrating body between the fixed electrode and the vibrating body.

Abstract: A force sensor is provided, the force sensor including: a first substrate; a metasurface pattern provided on a principal surface; a protective layer covering the metasurface pattern; a second substrate provided so as to face the first substrate; a reflective layer provided on a second principal surface; and a spacer defining a spacing between the first substrate and the second substrate, so that the force sensor is capable of offering desired response characteristics specified at the time of design.

Abstract: An ophthalmic information processing apparatus includes an acquisition unit and a disease estimation unit. The acquisition unit is configured to acquire a plurality of images with different cross-sectional orientations from each other of a subject’s eye. The disease estimation unit is configured to output estimation information for estimating whether or not the subject’s eye is a glaucoma eye from the images, using a plurality of learned models obtained by performing machine learning for each type of the images.

Abstract: Provided is a method for manufacturing a force sensor including: preparing a first substrate which is made of a material that transmits electromagnetic waves and includes on its surface a metal array arranged in a periodic pattern and a second substrate which includes on its surface a metal layer that reflects electromagnetic waves; forming a spacer member on the surface of the first substrate; forming a first metal layer around the spacer member on the surface of the first substrate; forming a second metal layer in a region corresponding to the first metal layer on the second substrate; and fusing the first metal layer and the second metal layer together to fix the first substrate and the second substrate in a state in which the spacer member formed on the surface of the first substrate abuts the surface of the second substrate.

Abstract: An ophthalmic information processing apparatus includes a determiner and a detector. The determiner is configured to determine a presence or absence of a disc hemorrhage for a front image of a fundus of a subject's eye, using a disc hemorrhage determination model obtained by performing machine learning using a plurality of fundus images labeled with labels indicating the presence or absence of a disc hemorrhage as first teaching data. The detector is configured to detect a disc hemorrhage region depicted in the front image that is determined to have the disc hemorrhage, using a disc hemorrhage region detection model obtained by performing machine learning using a plurality of pairs of image groups as second teaching data, each pair having a front image of a fundus and a disc hemorrhage region image representing a disc hemorrhage region depicted in the front image.

Abstract: Provided is a force sensor including: a first substrate that is made of a material that transmits electromagnetic waves and includes a metal array arranged in a periodic pattern on its surface; a second substrate that is disposed to face the first substrate with a gap therebetween and includes a metal layer that reflects the electromagnetic waves transmitted through the first substrate on its surface; a connecting member configured to connect the first substrate to the second substrate and define an internal space that houses the metal array and the metal layer; and an inert substance that fills the internal space.

Abstract: A LiMnO2 production method includes generating cubic crystal LiMnO2 nanoparticles by adding an organic solvent, manganese oxide nanoparticles, and lithium amide in a reaction vessel and heating in an inert atmosphere. and a washing and recovering the generated particles. Wurtzite type MnO nanoparticles are preferably used as the manganese oxide. As a result, LiMnO2 nanoparticles that have a substantially similar particle size to wurtzite type MnO nanoparticles can be obtained from an Mn raw material. Nanoparticles having a hollow structure can be obtained by controlling the reaction temperature.

Abstract: The present invention provides a transmission guided-mode resonant grating integrated spectroscopy device (transmission GMRG integrated spectroscopy device) characterized by comprising, disposed in this order on an optical detector array in which a plurality of diodes are mounted on a substrate made of a semiconductor: a transparent spacer layer; a waveguide layer; a transparent buffer layer provided as desired; a transmission metallic grating layer having a thickness causing surface plasmon; and a transparent protection film layer which is provided as desired.

Abstract: A flow control method is a flow control method of controlling flow around a blade of a rotary wing, a plasma actuator being disposed at the blade. The flow control method includes: determining a characteristic frequency ratio that is a characteristic value among frequency ratios, each of the frequency ratios being a ratio between an actuator driving frequency and an angle of attack changing frequency, the actuator driving frequency being a frequency of an applied voltage applied to the plasma actuator, the angle of attack changing frequency being a frequency at which an angle of attack of the blade changes in accordance with a rotation angle of the blade; setting the actuator driving frequency such that the frequency ratio becomes the characteristic frequency ratio; and applying a voltage of the set actuator driving frequency to the plasma actuator to control the flow around the blade.

Abstract: A peptide represented by (i) or (ii) below: (i) a peptide having an amino acid sequence represented by EEG(X1)QD(X2)EPEA, wherein X1 and X2 are identical or different and are Y, F, or W; or (ii) a peptide having an amino acid sequence where one or several amino acids are deleted, substituted, or added in amino acid positions excluding X1 and X2 of the amino acid sequence of (i) above and having an activity of binding to FABP3 protein.

Abstract: A rare earth-iron-nitrogen-based magnetic powder according to this invention contains, as main constituent components, a rare-earth element (R), iron (Fe), and nitrogen (N). Moreover, this magnetic powder has an average particle size of 1.0-10.0 ?m, and contains 22.0-30.0 mass % of a rare-earth element (R) and 2.5-4.0 mass % of nitrogen (N). Further, this magnetic powder includes: a core part having any one crystal structure among a Th2Zn17 type, a Th2Ni17 type, and a TbCu7 type; and a shell layer provided on the surface of the core part and having a thickness of 1-30 nm. The shell layer contains a rare-earth element (R) and iron (Fe) so that the R/Fe atomic ratio is 0.3-5.0, and further contains 0-10 at % (exclusive of 0) of nitrogen (N). Furthermore, this magnetic powder contains compound particles composed of a rare-earth element (R) and phosphorus (P).

Abstract: A variable embedding method, for solving a large-scale problem using dedicated hardware by dividing variables of a problem graph into partial problems and by repeating an optimization process of the partial problems when an interaction of the variables of an optimization problem is expressed in the problem graph, includes: determining whether a duplicate allocation of the variables of the optimization problem to the vertices of the hardware graph is required when embedding at least a part of all the variables into the vertices of the hardware graph; and selecting one of the variables requiring no duplicate allocation and embedding selected variable in one of the vertices of the hardware graph without using another one of the variables requiring the duplicate allocation as one of the variables of the partial problem.

Abstract: The present invention provides a vaccine composition for treating or preventing cancer expressing VASH2, containing a peptide including an amino acid sequence represented by SEQ ID NO: 4.

Abstract: System include an ultrasonic transducer configured to couple to a nondestructive testing (NDT) sample and configured to produce and direct an ultrasonic probe wave at a selected frequency into a subsurface region of the NDT sample, a 3D laser scanning vibrometer configured to direct a detection beam in a scan area on a surface of the NDT sample and to receive a return beam from the scan area, and to detect, based on the return beam, a 3D motion of the surface across a wideband frequency range, and a processor, and a memory configured with instructions that, when executed by the processor, cause the processor to produce sub-surface image data of the NDT sample at multiple harmonics of the selected frequency in the wideband frequency range based on the detected 3D surface motion, wherein the sub-surface image data describes a nonlinear defect response produced in the NDT sample by interaction of the ultrasonic probe wave with the subsurface region.

Abstract: A storage circuit includes: the array of a memory cell MC including a variable-resistance element; a conversion circuit that converts the resistance value of each memory cell into the signal level of an electric signal; a reference signal generation circuit that generates a reference signal common to a plurality of columns; a correction circuit that corrects one of the signal level of the reference signal and the signal level of the electric signal for each column of the array of the memory cell; and an RW circuit that determines data stored in the memory cell belonging to a corresponding column by comparing one of the reference level and the signal level of the electric signal, corrected by the correction circuit, and the other of the reference level and the signal level of the electric signal.

Abstract: The signal processing system generates image data, based on an electric signal group output from a radiation detector, and recognizes the electric signal group as a processing target, and the electric signal group includes at least part of an electric signal group meeting the following requirements: the electric signal group is an electric signal group with a signal value within a predetermined range, the electric signal group corresponding to a gamma ray with energy equal to or less than 375 keV; the predetermined range is equal to or greater than 50% and equal to or less than 80% relative to a 100% signal value; and the 100% signal value is a signal value detected when a gamma ray with energy of 511 keV enters a radiation detection element in the radiation detector and is totally absorbed by the radiation detection element.

Abstract: A method of treating a disease that is treatable through inhibition of at least one kinase selected from the group consisting of CDK7, CDK4, CDK6, PIM2, TSSK3, MST4, NEK6, MAP3K, MST3, DDR1, SPHK1, CaMK1, AurA, BRK, CaMK4, and PIM1, the method comprising administering an effective dose of a compound represented by the following formula (1) or a salt thereof to a patient: