Patents Assigned to Tokyo Institute of Technology
  • Patent number: 11433378
    Abstract: Provided are an intermetallic compound having high stability and high activity, and a catalyst using the same. A hydrogen storage/release material containing an intermetallic compound represented by formula (1): RTX . . . (1) wherein R represents a lanthanoid element, T represents a transition metal in period 4 or period 5 in the periodic table, and X represents Si, Al or Ge.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: September 6, 2022
    Assignees: JAPAN SCIENCE AND TECHNOLOGY AGENCY, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Hideo Hosono, Yutong Gong, Jiazhen Wu, Masaaki Kitano, Toshiharu Yokoyama, Yangfan Lu, Tiannan Ye
  • Publication number: 20220277224
    Abstract: A prediction device extracts each predictive feature vector expressing a feature from a peptide that is a target for membrane permeability prediction. The prediction device generates a predicted value of membrane permeability of the prediction target peptide by inputting plural predictive feature vectors into a trained model pre-trained to output a predicted value of peptide membrane permeability.
    Type: Application
    Filed: January 18, 2022
    Publication date: September 1, 2022
    Applicant: Tokyo Institute of Technology
    Inventors: Yutaka AKIYAMA, Masahito OHUE, Keisuke YANAGISAWA, Yasushi YOSHIKAWA, Masatake SUGITA, Takuya FUJIE, Satoshi SUGIYAMA, Shotaro MURATA
  • Patent number: 11428948
    Abstract: A blur compensation system includes: a mirror on which light of an image from a predetermined position is incident and which reflects light of a specific wavelength such that an incidence angle and an emission angle of the light of the specific wavelength are different from each other; a mirror that is disposed at a position on which the light of an image which is reflected by the mirror is incident and reflects the light of the specific wavelength such that an incidence angle and an emission angle of the light of the specific wavelength are different from each other; and a lens that is disposed on an optical axis of the light of an image between the mirror and the mirror and changes a direction of the light of an image which is reflected by the mirror such that light of a wavelength other than the specific wavelength out of the light of an image which is reflected by the mirror is emitted in the same direction as the light of the specific wavelength from an emission position of the light of the specific wave
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: August 30, 2022
    Assignees: NTT DOCOMO, INC., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Shinji Kimura, Kazuhiko Takahashi, Yuji Aburakawa, Masahiro Yamaguchi, Tomoya Nakamura, Shunsuke Igarashi
  • Publication number: 20220267705
    Abstract: A co-culture apparatus includes: a first airtight container; a co-culture device disposed outside of the first airtight container; a first culture medium source disposed in the first airtight container and storing a first culture medium; a second culture medium source storing a second culture medium having a lower dissolved oxygen concentration than that of the first culture medium; and a first conduit connected to the co-culture device and the first culture medium source. The co-culture device includes: a membrane having a first main surface, and a second main surface opposite to the first main surface for culturing cells; a first flow path partially defined by the first main surface and disposed such that the first culture medium flows therethrough; and a second flow path partially defined by the second main surface and disposed such that the second culture medium flows therethrough. The first flow path has an inlet connected to the first conduit.
    Type: Application
    Filed: February 24, 2022
    Publication date: August 25, 2022
    Applicants: SHIMADZU CORPORATION, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Yoichi FUJIYAMA, Yoh-ichi TAGAWA
  • Publication number: 20220265836
    Abstract: A complex is provided comprising a conjugate in which a polymer having a boronic acid group and a compound having a diol structure are bonded, and a substance that is complexed with the conjugate.
    Type: Application
    Filed: May 29, 2020
    Publication date: August 25, 2022
    Applicants: TOKYO INSTITUTE OF TECHNOLOGY, KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION
    Inventors: Nobuhiro Nishiyama, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Makoto Matsui, Hiroaki Kinoh, Kazunori Kataoka, Xueying Liu, Anjaneyulu Dirisala
  • Publication number: 20220251557
    Abstract: The purpose of the present invention is to reduce the strong hepatotoxicity of antisense nucleic acids that incorporate an artificial nucleobase (e.g., LNA). The present invention provides a bridged antisense nucleic acid for which antisense nucleic acid-induced toxicity is reduced by the supplemental addition to the wing region of a specific artificial nucleobase (e.g., MCA), while retaining the sequence of the antisense nucleic acid and the number of artificial nucleobases (e.g., LNA). The present invention also provides an antisense nucleic acid drug having a remarkably-reduced hepatotoxicity.
    Type: Application
    Filed: November 27, 2020
    Publication date: August 11, 2022
    Applicant: TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Kohji SEIO, Yoshiaki MASAKI, Takahito TOMORI
  • Publication number: 20220244248
    Abstract: As a simple antigen detection approach using Q-body, provided is a kit for antigen detection, comprising: a first peptide conjugated with two fluorescent dyes capable of forming a FRET pair or a fluorescent dye and a luminescent material capable of forming a BRET pair, and an antibody fragment with a second peptide added thereto, wherein 1) one of the first peptide and the second peptide is positively charged, and the other peptide is negatively charged, and 2) the first peptide and the second peptide are capable of forming a coiled coil.
    Type: Application
    Filed: June 3, 2020
    Publication date: August 4, 2022
    Applicant: TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Hiroshi UEDA, Tetsuya KITAGUCHI, Yuki OHMURO, Takanobu YASUDA, Akihito INOUE
  • Patent number: 11401369
    Abstract: An object of the present invention is to provide a novel rotaxane and a production method of the same. The present invention provides a rotaxane polyurea having a cyclic molecule and a polyurea chain piercing through the cyclic molecule.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: August 2, 2022
    Assignees: SUMITOMO RUBBER INDUSTRIES, LTD., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Toshiyuki Tarao, Mami Tanaka, Toshikazu Takata, Yosuke Akae
  • Patent number: 11402755
    Abstract: A chemically amplified positive-type photosensitive resin composition capable of forming a resist pattern having excellent cross-sectional perpendicularity of a nonresist section even when a resist pattern is formed on a metal surface, and a method for manufacturing a substrate with a template and a method for manufacturing a plated article using the composition. The composition contains an acid generator, a resin, and a sulfur-containing compound including a sulfur-containing compound and a thiol compound that is different from the sulfur-containing compound.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: August 2, 2022
    Assignees: Tokyo Ohka Kogyo Co., Ltd., Tokyo Institute of Technology
    Inventors: Yasushi Kuroiwa, Yuta Yamamoto
  • Patent number: 11404396
    Abstract: This semiconductor device includes a memory semiconductor chip in which a plurality of memory cells are laminated on a semiconductor substrate, a planar buffer chip which is a semiconductor chip that comprises a plurality of buffer circuits which hold data read from the memory cell and data written to the memory cell and which output the held data in accordance with the number of bit lines of the plurality of memory cells, and an electrical connection structure which electrically connects the bit lines of the memory cells of the memory semiconductor chips and the buffer circuits of the planar buffer chips to each other in a thickness direction of the memory semiconductor chip and the planar buffer chip. The electrical connection structure electrically connects the bit lines of the plurality of memory cells in the thickness direction through a penetration electrode penetrating at least the plurality of memory cells in the thickness direction.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: August 2, 2022
    Assignees: HONDA MOTOR CO., LTD., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Koji Sakui, Takayuki Ohba
  • Patent number: 11398331
    Abstract: An actuator includes a first magnet whose magnetic pole surface has an N pole and a second magnet whose magnetic pole surface has an S pole. When current flows from one end of a first wiring to the other end, the current circulates in one direction at least partially on the first magnet in a first area, while it circulates in a direction opposite to the one direction at least partially on the second magnet in the first area. When current flows from one end of a second wiring to the other end, the current circulates in the direction opposite to the one direction at least partially on another first magnet in the second area, while it circulates in the one direction at least partially on another second magnet in the second area.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: July 26, 2022
    Assignees: TDK CORPORATION, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Kenichi Suzuki, Akira Suzuki, Shusuke Ichihashi, Tadahiko Shinshi, Noriei Azuma
  • Patent number: 11390788
    Abstract: Provided are a chemical heat storage material having excellent cyclic durability and a method for producing the same. A chemical heat storage material includes: a surface layer formed of silica and/or calcium silicate; and calcium oxide particles with the surface layer.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: July 19, 2022
    Assignees: SHIRAISHI CENTRAL LABORATORIES CO., LTD., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Masahiko Tajika, Yukitaka Kato, Naoto Uchiyama, Hiroki Takasu
  • Patent number: 11384112
    Abstract: Provided is an artificial nucleoside or artificial nucleotide capable of composing an artificial oligonucleotide having superior nuclease resistance. The artificial nucleoside or artificial nucleotide is a compound represented by formula (I) or a salt thereof (wherein, Bx represents a pyrimidine base or purine base, R1, R2, R3 and R4 represent hydrogen atoms, C1-6 alkyl groups or the like, Y represents NR5R6 (wherein, R5 and R6, independently of each other, represent a hydrogen atom, C1-6 alkyl group or the like, or R5 and R6, together with a nitrogen atom bound thereto, form a 3- to 11-membered nitrogen-containing non-aromatic heterocyclic group) or an optionally substituted C2-9 aromatic heterocyclic group, Z1 and Z2 represent hydrogen atoms, hydroxyl group-protecting groups, phosphorous-containing groups or the like, and n represents an integer of 1 to 3).
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: July 12, 2022
    Assignees: TOKYO INSTITUTE OF TECHNOLOGY, NISSAN CHEMICAL CORPORATION
    Inventors: Kohji Seio, Yoshiaki Masaki, Keishi Yamamoto, Keita Yoshida, Yusuke Iriyama, Hiroyuki Nakajima, Tatsuro Kanaki
  • Patent number: 11378397
    Abstract: A change in geoid height is measured easily. A geoid measurement method of the present invention executes an inertial measurement data acquiring step, a comparison data acquiring step, a state variable estimating step, and a geoid calculating step. In the inertial measurement data acquiring step, data related to velocity, position, and attitude angle is acquired as inertially-derived data based on the output of an inertial measurement part having a three-axis gyro and a three-axis accelerometer attached to a moving body. In the comparison data acquiring step, data related to velocity is acquired as comparison data from a source other than the inertial measurement part. In the state variable estimating step, state variables including a plumb line deviation are estimated by using the inertially-derived data and the comparison data to apply a Kalman filter in which the plumb line deviation is included in the state variables.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: July 5, 2022
    Assignees: JAPAN AVIATION ELECTRONICS INDUSTRY, LIMITED, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Mikio Kozuma, Ryotaro Inoue, Toshiyuki Hosoya, Atsushi Tanaka
  • Patent number: 11377593
    Abstract: In a phosphor according to an aspect, an emission site has a perovskite crystal structure expressed by ABX3, in which A and B are each a cation and X is an anion, and an emission element is located at a B site serving as a body center of the perovskite crystal structure.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: July 5, 2022
    Assignees: KOITO MANUFACTURING CO., LTD., TOKYO INSTITUTE OF TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Hisayoshi Daicho, Yu Shinomiya, Kiminori Enomoto, Hideo Hosono, Satoru Matsuishi, Hiroshi Sawa, Akitoshi Nakano
  • Patent number: 11376266
    Abstract: The present invention is directed to provide antitumor agent including water-soluble sulfasalazine as an active ingredient. Antitumor agents were obtained with, as the water-soluble sulfasalazine, a PEG-modified sulfasalazine represented by the following formula: wherein an average value of n is 4 or larger and 1136 or smaller.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: July 5, 2022
    Assignees: Keio University, Tokyo Institute of Technology
    Inventors: Hideyuki Saya, Osamu Nagano, Kenji Tsuchihashi, Kentaro Suina, Nobuhiro Nishiyama, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Naoki Yamada, Tsukasa Nishimori
  • Publication number: 20220200612
    Abstract: This atomic resonator for causing a resonance frequency by CPT resonance includes: a gas cell having alkali metal atoms enclosed; a photodetector configured to detect light having passed through the gas cell and convert the light to an electric signal; a high-frequency oscillator configured to receive the electric signal and output the signal after a frequency thereof is divided by two; and a laser light source configured to modulate and introduce, into the gas cell, light based on the signal output from the high-frequency oscillator. The high-frequency oscillator has an injection-locked frequency divider circuit including an acoustic resonator as an oscillation element.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Applicants: National Institute of Information and Communications Technology, Tokyo Institute of Technology
    Inventors: Motoaki HARA, Yuichiro YANO, Masatoshi KAJITA, Tetsuya IDO, Hiroyuki ITO
  • Patent number: 11357443
    Abstract: A determination result output device and a determination result output system output a determination result indicating various states of a subject, and a determination result provision device provides a determination result. A determination result output system includes a determination result output device that outputs a determination result indicating the state of a subject, and a determination result provision device that provides the determination result. When acquiring facial-surface change information related to a target purpose from the determination result output device, the determination result provision device generates determination information from facial-surface change information, determines a determination result including a state level of the subject, and sends the determination result to the determination result output device.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: June 14, 2022
    Assignees: Daikin Industries, Ltd., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Junichiro Arai, Yasunori Kotani, Taro Tomatsu, Yoshimi Ohgami
  • Publication number: 20220178012
    Abstract: Provided is a method for forming a ferroelectric film of a metal oxide having a fluorite-type structure at a low temperature of lower than 300° C., and a ferroelectric film obtained at a low temperature. The present invention provides a production method of a ferroelectric film comprising a crystalline metal oxide having a fluorite-type structure of an orthorhombic crystal phase, which comprises using a film sputtering method comprising sputtering a target at a substrate temperature of lower than 300° C., to deposit on the substrate a film of a metal oxide which is capable of having a fluorite-type structure of an orthorhombic crystal phase, and having a subsequent thermal history of said film of lower than 300° C.; or applying an electric field to said film after said deposition or after said thermal history of lower than 300° C.
    Type: Application
    Filed: April 27, 2020
    Publication date: June 9, 2022
    Applicant: Tokyo Institute of Technology
    Inventors: Hiroshi FUNAKUBO, Takao SHIMIZU, Takanori MIMURA, Yoshiko NAKAMURA, Reijiro SHIMURA, Yu-ki TASHIRO
  • Publication number: 20220153992
    Abstract: An intracellularly degraded branched and degradable polyethylene glycol derivative represented by the following formula (1): wherein each symbol is as defined in the present specification, that is used for modifying bio-related substances is provided by the present invention.
    Type: Application
    Filed: March 26, 2020
    Publication date: May 19, 2022
    Applicants: NOF CORPORATION, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Hiroki YOSHIOKA, Kazuki OSAKAMA, Mika HAMURA, Takanori INABA, Nobuhiro NISHIYAMA, Makoto MATSUI, Hiroyasu TAKEMOTO, Takahiro NOMOTO, Xiaohang SUN