Patents Assigned to TOKYO UNIVERSITY OF SCIENCE FOUNDATION
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Patent number: 11932666Abstract: Provided is a polymerizable compound represented by a Formula E-1 or Formula E-2 shown in the description. In Formula E-1 or Formula E-2, R1 represents an alkoxy group, —NRN2, a hydroxy group, an aryl group, or an alkyl group, wherein RN each independently represents a hydrogen atom or an alkyl group having 1 to 10 carbon atoms; n represents an integer from 1 to 5; R3 represents a hydrogen atom, an acetyl group, a phenoxyacetyl group, a pivaloyl group, a benzyl group, a 4-methoxybenzyl group, a benzoyl group, a triphenylmethyl group, a 4,4?-dimethoxytrityl (DMTr) group, a 4-methoxytrityl (MMTr) group, a 9-phenylxanthenyl group, a trimethylsilyl group, a cyanomethoxymethyl group, a 2-(cyanoethoxy)ethyl group, or a cyanoethoxymethyl group; and X represents a structure represented by any one of Formula B-1 to Formula B-5 shown in the description.Type: GrantFiled: October 13, 2022Date of Patent: March 19, 2024Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Takeshi Wada, Tatsuya Saito, Yuka Ishii, Yohei Nukaga
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Patent number: 11920045Abstract: To provide an active-energy-ray-curable composition including a compound represented by General Formula (I) below: where in the General Formula (I), R is hydrogen or a methyl group; A is a structure expressed by one selected from the group consisting of Structural Formulas (II) to (VII) below, each of which may have a substituent such as an alkyl group or an alkoxy group, or both; j and k in the Structural Formulas (VI) and (VII) are an integer of 0 or more; X denotes a substituent including a heteroatom; n is an integer of 0 or more, m is an integer of 1 or more, and n+m is 3 or more, or n is an integer of 0 and m is an integer of 2; and wavy lines in the Structural Formulas (II) to (VII) each independently denote a bond with X or a (meth)acryloyl group (H2C?CR—C(?O)—):Type: GrantFiled: April 1, 2020Date of Patent: March 5, 2024Assignees: Ricoh Company, Ltd., Tokyo University of Science FoundationInventors: Soh Noguchi, Mitsunobu Morita, Takashi Okada, Tatsuki Yamaguchi, Koji Arimitsu
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Patent number: 11920076Abstract: A fire retardant material comprising a carbon fiber which tensile elasticity is 700 GPa or more, and a fire retardant resin such as polycarbonate.Type: GrantFiled: October 12, 2018Date of Patent: March 5, 2024Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Koichi Yonemoto, Kiyoto Murakami, Satoshi Nonaka
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Patent number: 11915883Abstract: An electret includes an electret layer. The electret layer is formed by subjecting a composite film in which inorganic dielectric particles are dispersed and held in a base film to a polarization treatment. The inorganic dielectric particles are mainly composed of an inorganic dielectric material having a bandgap energy of 4 eV or more.Type: GrantFiled: December 9, 2020Date of Patent: February 27, 2024Assignees: DENSO CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Noriyuki Matsushita, Yoshihiro Kozawa, Kazuhiko Kanoh, Yumi Tanaka, Hirotoshi Otsuka, Yuki Kotaka
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Patent number: 11917919Abstract: An electret includes a substrate and an electret layer formed above a surface of the substrate. The electret layer is a composite metal compound containing two or more different metal elements, and is obtained by subjecting a thin film mainly composed of an inorganic dielectric material having a bandgap energy of 4 eV or more to a polarization treatment.Type: GrantFiled: December 9, 2020Date of Patent: February 27, 2024Assignees: DENSO CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Noriyuki Matsushita, Yoshihiro Kozawa, Kazuhiko Kanoh, Yumi Tanaka
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Publication number: 20240019430Abstract: Novel factors which are involved in the mechanism of the onset of IgA nephropathy are explored, and diagnostic, preventive or therapeutic agents for this disease are provided. A method for measuring autoantibodies related to IgA nephropathy, the method comprising measuring the amount of anti-spectrin ? IgA antibodies in a sample derived from a living organism.Type: ApplicationFiled: December 3, 2021Publication date: January 18, 2024Applicants: JUNTENDO EDUCATIONAL FOUNDATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Yusuke SUZUKI, Yoshihito NIHEI, Daisuke KITAMURA
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Patent number: 11873380Abstract: A photoreactive composition including a base-reactive compound, a photobase generator that is represented by the following Formula (1) and that generates a base when irradiated with light, and at least one compound selected from the group consisting of a polycyclic aromatic compound having a fused ring structure having two or more rings and a polycyclic aromatic compound having three or more aromatic rings and having a conjugated structure including any two or more of the three or more aromatic rings, in which the base-reactive compound is a compound having two or more groups that will have their polarity converted by the action of a base and that exhibit reactivity, in one molecule, or a compound having two or more groups that will react under the action of a base, in one molecule.Type: GrantFiled: May 7, 2019Date of Patent: January 16, 2024Assignee: Tokyo University of Science FoundationInventor: Koji Arimitsu
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Patent number: 11873354Abstract: A photobase generator includes a compound including a first skeleton represented by the following formula (a), and a second skeleton including a nitrogen atom bonding to a bonding position of the first skeleton to form an amide group, wherein the compound generates a base, in which a hydrogen atom is bonding with the nitrogen atom of the second skeleton, by light irradiation, and the pKa of a conjugate acid of the base in water is 12 or more. In formula (a), G is a divalent aromatic group, and * represents the bonding position with the nitrogen atom.Type: GrantFiled: September 10, 2020Date of Patent: January 16, 2024Assignee: Tokyo University of Science FoundationInventor: Koji Arimitsu
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Publication number: 20230407127Abstract: A coating agent has: a film-forming component containing an organosilicon compound having a radical polymerizable functional group and an alkoxysilyl group; and a film-curing component composed so that a base and a radical can be generated on irradiation with ultraviolet light. The film-curing component includes a nonionic photobase generator having no ionic bond in the molecular structure. The content of the nonionic photobase generator is 0.1 parts by mass or more and 50 parts by mass or less, based on 100 parts by mass of the organosilicon compound.Type: ApplicationFiled: November 12, 2021Publication date: December 21, 2023Applicants: KABUSHIKI KAISHA TOYOTA JIDOSHOKKI, Tokyo University of Science FoundationInventors: Ayano SASAKI, Sayako SATO, Hidenori MUNEKATA, Motoshige ISOBE, Hisashi MURAMATSU, Koji ARIMITSU
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Patent number: 11817261Abstract: An ink includes a boron-doped nanodiamond having a specific surface area of 110 m2/g or greater, and electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater.Type: GrantFiled: November 18, 2021Date of Patent: November 14, 2023Assignees: DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Takeshi Kondo, Tatsuo Aikawa, Makoto Yuasa, Kenjo Miyashita, Masahiro Nishikawa, Takahiro Tei
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Publication number: 20230288238Abstract: The sensor of a fluid sensor system includes an outer peripheral sensor unit including three or more sensor pairs to surround and sandwich the heating element. The computing device of the system includes a first identification unit identifies a sensor pair in which an output difference between an output value corresponding to a temperature detected by one temperature sensor of the sensor pair and an output value corresponding to a temperature detected by the other temperature sensor of the sensor pair is largest, a second identification unit identifies other sensor pairs adjacent to the identified sensor pair in the circumferential direction, and a flow direction estimation unit estimates the flow direction of the fluid on the basis of the output difference in the sensor pair having the largest output difference and output differences in the other sensor pairs adjacent to the sensor pair in the circumferential direction.Type: ApplicationFiled: February 28, 2023Publication date: September 14, 2023Applicants: MITSUBISHI HEAVY INDUSTRIES, LTD., Tokyo University of Science FoundationInventors: Shunsuke MIZUMI, Naoto OMURA, Masahiro MOTOSUKE, Daiki SHIRAISHI, Koichi MURAKAMI
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Patent number: 11742153Abstract: Provided is an electrode-forming material for an electrochemical capacitor useful for forming an electrode of an electrochemical capacitor having a high storage capacity and a high energy density. The electrode-forming material for an electrochemical capacitor according to an embodiment of the present invention includes boron-doped nanodiamond (A) having a specific surface area of 110 m2/g or greater and an electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater; and a metal oxide (B), and the content of the (B) is from 20 to 95 mass % with respect to the total content of the (A) and (B).Type: GrantFiled: February 28, 2020Date of Patent: August 29, 2023Assignees: DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Takeshi Kondo, Toshifumi Tojo, Makoto Yuasa, Kenjo Miyashita, Atori Miki, Masahiro Nishikawa, Takahiro Tei
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Patent number: 11718590Abstract: A compound represented by Chemical formula 1: wherein n is an integer of 2 or more, is provided. Also provided is a derivatization reagent for derivatizing a diene-containing compound, including a compound represented by Chemical formula 1. Further provided is a synthesis method for a compound, including a nucleophilic substitution reaction between an aryl halide and a heterocyclic amine compound being saturated, the compound being represented by Chemical formula 1.Type: GrantFiled: December 21, 2021Date of Patent: August 8, 2023Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, JEOL Ltd.Inventors: Tatsuya Higashi, Shoujiro Ogawa, Masaki Takiwaki, Seketsu Fukuzawa
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Publication number: 20230220022Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.Type: ApplicationFiled: January 3, 2023Publication date: July 13, 2023Applicants: The University of Tokyo, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Kouji MATSUSHIMA, Satoshi UEHA, Shungo DESHIMARU, Chang-Yu CHEN, Shoji YOKOCHI, Yoshiro ISHIWATA, Shiro SHIBAYAMA
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Patent number: 11637230Abstract: The purpose of the present invention is to provide a thermoelectric conversion element having a film which not only maintains sufficient adhesion even when exposed to a high temperature but also exhibits excellent oxidation resistance and crack resistance. The problem is solved by a thermoelectric conversion element including a thermoelectric conversion component, in which the thermoelectric conversion component contains magnesium silicide and/or manganese silicide and is covered with a film containing Si and Zr.Type: GrantFiled: June 28, 2019Date of Patent: April 25, 2023Assignees: Nihon Parkerizing Co., Ltd., Tokyo University of Science FoundationInventors: Junichi Uchida, Yuki Haijima, Yuki Sueuchi, Tsutomu Iida
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Publication number: 20230124539Abstract: The present invention provides a binder for positive electrode of lithium ion battery which is excellent in workability at the time of producing a positive electrode, is excellent in charge and discharge characteristics such as cycle characteristics and rate characteristics, and enables to possible to produce a positive electrode having an extended cycle life, as well as the present invention provides a slurry for forming positive electrode mixture layer of lithium ion battery, a positive electrode for lithium ion battery, and a lithium ion battery, using the same.Type: ApplicationFiled: February 25, 2021Publication date: April 20, 2023Applicants: Tokyo University of Science Foundation, TOSOH CORPORATIONInventors: Tatsuo HORIBA, Kei KUBOTA, Yoshinari ABE, Asako OISHI, Shinichi KOMABA, Hiroshi INOUE, Eiichi TOUGOU
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Publication number: 20230115206Abstract: A sign detection device is provided with a plurality of sensors, a data acquisition unit, a calculation unit, and a detection unit. The plurality of sensors are respectively disposed at a plurality of positions of a detection target to measure a physical parameter at each positions. The data acquisition unit is configured to acquire time-series change data of the physical parameters from the plurality of sensors. The calculation unit is configured to calculate dynamic network information representing a time change of a complex network structure including a parameter indicating a correlation between the physical parameters at any two positions of the plurality of positions, on the basis of the time-series change data. The detection unit is configured to detect a sign of sudden change vibration of the detection target, on the basis of the dynamic network information.Type: ApplicationFiled: October 5, 2022Publication date: April 13, 2023Applicants: MITSUBISHI HEAVY INDUSTRIES, LTD., Tokyo University of Science FoundationInventors: Tomohito NAKAMORI, Keisuke MATSUYAMA, Takuya KUROSAKA, Hiroshi GOTODA, Natsumi KIKUTA
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Patent number: 11578132Abstract: It is an object of the present invention to provide a method for efficiently producing a B cell population comprising B cells that recognize a specific antigen. According to the present invention, provided is a method for producing a B cell population, comprising: a step (c) of culturing a cell population comprising B cells together with a specific antigen in the absence of IL-21, in the absence of IL-4, and in the presence of a cytokine other than IL-21 and IL-4, while giving stimulation mediated by CD40 and a BAFF receptor to the cells; and a step (d) of culturing the cell population comprising B cells, while giving stimulation mediated by has to the cells, so as to obtain a B cell population comprising B cells that recognize the specific antigen.Type: GrantFiled: January 15, 2018Date of Patent: February 14, 2023Assignees: KANEKA CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Tatsuya Moutai, Tomoyuki Nakaishi, Hiroshi Kita, Mitsuaki Kitano, Daisuke Kitamura
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Patent number: 11572393Abstract: Disclosed are a novel therapeutic means effective and practical against cancer, and a novel substance useful as such a therapeutic means. Provided are novel peptides derived from a partial region of HMGN1, HMGN2, HMGN4 or HMGN5, and anti-cancer agents and anti-cancer effect enhancers containing the peptide as an active ingredient. The peptide of the present invention has an anti-tumor effect even independently, and exerts a remarkably excellent anti-tumor effect particularly when used in combination with an immune checkpoint regulator, or an anti-CD4 antibody or antigen-binding fragment thereof.Type: GrantFiled: March 7, 2019Date of Patent: February 7, 2023Assignees: THE UNIVERSITY OF TOKYO, ONO PHARMACEUTICAL CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Kouji Matsushima, Satoshi Ueha, Shungo Deshimaru, Chang-Yu Chen, Shoji Yokochi, Yoshiro Ishiwata, Shiro Shibayama
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Patent number: 11558694Abstract: An electret includes a composite oxide having an ABO3 type perovskite structure containing two different metal elements A and B. The composite oxide is in a polarized state, at least a part of one of the metal elements A and B is substituted with a dopant element having a lower valence than the one of the metal elements A and B, and the composite oxide has a bandgap energy of 4 eV or more.Type: GrantFiled: December 9, 2020Date of Patent: January 17, 2023Assignees: DENSO CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Yoshihiro Kozawa, Noriyuki Matsushita, Kazuhiko Kanoh, Yumi Tanaka, Tomoya Maruyama, Hiroshi Okamoto, Naoya Morioka, Katsuyoshi Saiki