Patents Assigned to TOKYO UNIVERSITY OF SCIENCE FOUNDATION
  • Publication number: 20230003813
    Abstract: Proposed is a phase shift introduction method, a structure, and a circuit device for eliminating or minimizing a risk associated with dissimilar materials, solving in principle a problem of mixing of a signal current and a control current that occurs due to DC connection of a phase shifter to a signal line, and stably and reliably providing a phase shift that is desired to be introduced without being adversely effected by noise generated by an ambient magnetic field, which is generated due to use of an external power supply. A structure according to the present invention includes a phase shifter 101 and a closed-loop circuit 103 that is directly used for computation or storage, and a quantum phase shift is generated in the closed-loop circuit 103 by using a fractional flux quantum captured by the phase shifter 101 that is DC-separated from the closed-loop circuit 103.
    Type: Application
    Filed: November 26, 2020
    Publication date: January 5, 2023
    Applicants: National Institute of Advanced Industrial Science and Technology, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, Tokyo University of Science Foundation
    Inventors: Yasumoto TANAKA, Hirotake YAMAMORI, Takashi YANAGISAWA, Shunichi ARISAWA, Taichiro NISHIO
  • Patent number: 11542292
    Abstract: Provided a polymerizable compound represented by the following Formula A-1 or Formula A-2: In Formula A-1 or Formula A-2, R1 represents an electron-donating group; n represents an integer from 1 to 5; R2 represents a hydrogen atom, a halogen atom, or —ORO, wherein RO represents a hydrogen atom, an alkyl group, or a protecting group of a hydroxy group; R3 represents a hydrogen atom or a protecting group of a hydroxy group; and X represents a structure represented by any one of Formula B-1 to Formula B-5.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: January 3, 2023
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Takeshi Wada, Tatsuya Saito, Yuka Ishii, Yohei Nukaga
  • Publication number: 20220380763
    Abstract: A novel anti-tumor agent capable of delivering siRNA or shRNA specifically to pancreatic cancer cells and suppressing tumor growth, invasion, and metastasis of pancreatic cancer is provided. The present invention provides a nucleic acid delivery enhancer for delivering siRNA or shRNA into cells, which consists of a folic acid-cationic oligopeptide complex. The present invention also provides an anti-tumor agent having siRNA or shRNA capable of binding to mRNA or snoRNA expressed in pancreatic cancer cells to inhibit its expression and a folic acid-cationic oligopeptide complex. The siRNA is capable of binding to RNA selected from the group consisting of, for example, SNORA18 snoRNA, NUP85 mRNA, WASF2 mRNA, and SNORA22 snoRNA.
    Type: Application
    Filed: October 26, 2020
    Publication date: December 1, 2022
    Applicants: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Keisuke TANIUCHI, Takeshi WADA, Rintaro HARA, Kazuki SATO, Kazunori TAKAGI
  • Publication number: 20220356462
    Abstract: A nucleic acid amplification method using a solid-phase carrier according to the present invention comprises: capturing a target nucleic acid comprising mRNA on a solid-phase carrier; carrying out complementary-strand synthesis on the solid phase; carrying out exonuclease treatment to degrade and remove unreacted target- capturing nucleic acid on the solid phase; and then carrying out mRNA degradation and homopolymer addition by TdT reaction in the presence of a chain-terminating nucleotide triphosphate. According to the method of the present invention, cDNA can be stably and highly efficiently amplified even from a small amount of sample even in cases where the ratio of the amount of enzyme to the DNA substrate on the solid phase is excessive, where the reaction time is excessive, and/or where reagents show lot-to-lot variation.
    Type: Application
    Filed: July 10, 2020
    Publication date: November 10, 2022
    Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Kouji MATSUSHIMA, Satoshi UEHA, Shigeyuki SHICHINO, Satoru ITO, Hiroyasu AOKI
  • Patent number: 11472109
    Abstract: A three-dimensional printing apparatus (1) allowing a linear filament (F) in which a fiber bundle (C) is impregnated with resin (P) to be continuously ejected includes twisting means (6) for allowing a total amount of twisting of the filament (F) or an amount of twisting of the fiber bundle (C) to be changed.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: October 18, 2022
    Assignees: NIHON UNIVERSITY, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Masahito Ueda, Ryosuke Matsuzaki, Yoshiyasu Hirano
  • Publication number: 20220313647
    Abstract: Disclosed is a novel measure that is effective in therapy etc. of psychiatric or neurological disorders or symptoms, such as anxiety or depressive disorders, and is unlikely to cause problems such as dependence and adverse effects and is highly safe. The present invention provides an agent for treating, preventing, or ameliorating psychiatric or neurological disorders or symptoms, wherein the agent contains any of the followings as an active ingredient: (1) disulfiram, (2) a metal complex of diethyldithiocarbamate, (3) a disulfide capable of generating diethyldithiocarbamate in the body, (4) a pharmaceutically acceptable salt of (1), (2), or (3), and (5) a solvate of (1), (2), (3), or (4).
    Type: Application
    Filed: September 25, 2020
    Publication date: October 6, 2022
    Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Akiyoshi SAITOH, Yuya TERASHIMA, Kouji MATSUSHIMA, Yoshitake SANO
  • Patent number: 11450445
    Abstract: A method for manufacturing an electroconductive pattern 40, provided with: a lamination step for laminating an acid generation film 10 containing an acid proliferation agent and a photoacid generator on a polymer film 20 containing an electroconductive polymer formed on a substrate 21; a masking step for masking the top of the acid generation film 10; a light irradiation step for irradiating the laminate from the acid-generation-film 10 side; a doping step for doping the electroconductive polymer with an acid generated and proliferated in the acid generation film 10 by the light irradiation; and a releasing step for releasing the acid generation film 10 from the polymer film 20. This method makes it possible to provide an electroconductive film and a method for manufacturing an electroconductive pattern in which photoacid generation and acid proliferation effects are utilized.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: September 20, 2022
    Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Koji Arimitsu, Makoto Wakabayashi
  • Publication number: 20220281746
    Abstract: An embodiment of the present invention provides a noble gas hydride having the following formula 1: NgnHm. In formula 1, Ng represents a noble gas atom, n represents an integer from 1-8, and m represents an integer from 1-46.
    Type: Application
    Filed: July 6, 2020
    Publication date: September 8, 2022
    Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventor: Kazuo WATANABE
  • Patent number: 11431686
    Abstract: An encrypted data processing system is provided including an encryption device and a server. The encryption device includes an encrypting section that encrypts first information based on a first encryption key and transmits the encrypted information for registration to the server, and encrypts second information based on a second encryption key and transmits the encrypted information to be compared to the server. The server includes a comparison section that employs a cipher comparison function for comparing encrypted information to compare the encrypted information for registration against the encrypted information to be compared, and transmits a comparison result to the encryption device. The encryption device further includes a comparison result decrypting section that employs a decryption function for decrypting the comparison result with the first encryption key and the second encryption key to find a degree of matching between the first information and the second information.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: August 30, 2022
    Assignee: Tokyo University of Science Foundation
    Inventors: Satoshi Iriyama, Maki Kihara
  • Patent number: 11405072
    Abstract: A communication method includes generating at a first node, a message of a predetermined message temporal length that indicates an input value to be encoded and transmitting, at the first node, a signal including a pulse train corresponding to the generated message. The signal including the pulse train includes two pulses that define start and end of the message, respectively, and further two pulses that define within the message, a first time interval calculated from the input value in accordance with a first function and a second time interval calculated from the input value in accordance with a second function, respectively.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: August 2, 2022
    Assignees: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Ferdinand Peper, Kenji Leibnitz, Tetsuya Shimokawa, Mikio Hasegawa, Kaori Kuroda
  • Publication number: 20220157536
    Abstract: Provided is an electrode-forming material for an electrochemical capacitor useful for forming an electrode of an electrochemical capacitor having a high storage capacity and a high energy density. The electrode-forming material for an electrochemical capacitor according to an embodiment of the present invention includes boron-doped nanodiamond (A) having a specific surface area of 110 m2/g or greater and an electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater; and a metal oxide (B), and the content of the (B) is from 20 to 95 mass % with respect to the total content of the (A) and (B).
    Type: Application
    Filed: February 28, 2020
    Publication date: May 19, 2022
    Applicants: DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Takeshi KONDO, Toshifumi TOJO, Makoto YUASA, Kenjo MIYASHITA, Atori MIKI, Masahiro NISHIKAWA, Takahiro TEI
  • Patent number: 11324809
    Abstract: Provided are: a pharmaceutical composition for curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor, in which the pharmaceutical composition contains a carbohydrate modifying enzyme as an active ingredient; and a method of curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: May 10, 2022
    Assignee: Tokyo University of Science Foundation
    Inventors: Yoichiro Iwakura, Tomonori Kaifu
  • Patent number: 11318441
    Abstract: The present invention provides a new hydrogen chloride removing agent that exhibits a good hydrogen chloride removal effect at a relatively low temperature. The present invention preferably provides a new hydrogen chloride removing agent for removing hydrogen chloride contained in a hydrogen-chloride-containing gas, such as a pyrolysis gas, a combustion exhaust gas, a dry distillation gas, etc., especially hydrogen chloride contained in a biomass pyrolysis gas. The present invention relates to a hydrogen chloride removing agent characterized by containing a mixture of a calcium carbonate and an imogolite and/or a synthetic imogolite, and relates to a method for removing, by using said hydrogen chloride removing agent, hydrogen chloride contained in a hydrogen-chloride-containing gas, especially hydrogen chloride contained in a biomass pyrolysis gas.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: May 3, 2022
    Assignees: JAPAN BLUE ENERGY CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Naoki Dowaki, Mitsuo Kameyama, Kiyoshi Dowaki
  • Patent number: 11273405
    Abstract: A method for recovering hydrogen which is capable of efficiently recovering high concentration hydrogen gas by adsorbing and removing hydrocarbon gas such as carbon dioxide from biomass pyrolysis gas under a relatively low pressure, and also capable of storing the recovered high concentration hydrogen gas, preferably, in a cartridge type container that can be used as is as a hydrogen storing container for an apparatus equipped with a fuel cell. The method includes a first purifying stare of purifying biomass pyrolysis gas and a second purifying stage of purifying the obtained purified gas under a pressure equal to or less than the pressure in the first purifying stage to recover gas that contains hydrogen, and further includes a hydrogen storing stage of feeding the gas containing hydrogen recovered in the second purifying stage into the container filled with a hydrogen storage alloy and storing high purity hydrogen.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: March 15, 2022
    Assignees: JAPAN BLUE ENERGY CO., LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Kiyoshi Dowaki, Noboru Katayama, Naoki Dowaki, Mitsuo Kameyama
  • Publication number: 20220076899
    Abstract: An ink includes a boron-doped nanodiamond having a specific surface area of 110 m2/g or greater, and electrical conductivity at 20° C. of 5.0×10?3 S/cm or greater.
    Type: Application
    Filed: November 18, 2021
    Publication date: March 10, 2022
    Applicants: DAICEL CORPORATION, TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Takeshi KONDO, Tatsuo AIKAWA, Makoto YUASA, Kenjo MIYASHITA, Masahiro NISHIKAWA, Takahiro TEI
  • Patent number: 11227726
    Abstract: An electrolyte solution for a potassium ion battery or a potassium ion capacitor, the electrolyte solution comprising at least one potassium salt compound selected from the group consisting of potassium bis(trifluoromethanesulfonyl)amide and potassium bis(fluorosulfonyl)amide and at least one solvent selected from the group consisting of ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, triethylene glycol dimethyl ether, tetraethylene glycol dimethyl ether, pentaethylene glycol dimethyl ether, ethylene carbonate, and propylene carbonate, in which a concentration of the potassium salt compound in the electrolyte solution is from 1.5 mol/kg to 12.0 mol/kg.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: January 18, 2022
    Assignee: Tokyo University of Science Foundation
    Inventors: Shinichi Komaba, Kei Kubota, Tomooki Hosaka
  • Publication number: 20210397097
    Abstract: A method of producing a molded product, the method including: pressing a mold having a surface including at least one of a concave part or a convex part against a photocurable positive electron beam resist; obtaining a molded product of the positive electron beam resist having a surface including a concave part and a convex part by irradiating the photocurable positive electron beam resist pressed against the resist with light to cure the resist; and partially decomposing the molded product of the positive electron beam resist in a region subjected to irradiation with an electron beam by irradiating the surface of the molded product of the positive electron beam resist with the electron beam.
    Type: Application
    Filed: July 26, 2019
    Publication date: December 23, 2021
    Applicants: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, TOYO GOSEI CO., LTD.
    Inventors: Jun TANIGUCHI, Takao OKABE, Takeshi OSAKI, Takashi MIYAZAWA
  • Patent number: 11193172
    Abstract: Novel means that enables prediction of prognosis of a patient with cancer or inflammatory disease is disclosed. In the method for prediction of prognosis of a patient with cancer or inflammatory disease according to the present invention, the expression level of the FROUNT gene in a sample collected from the patient is measured. Since FROUNT is a poor prognostic factor, the lower the expression level of the FROUNT gene is, the better the prognosis in the patient is predicted to be. Or, the expression level of the CC chemokine receptor/ligand gene in a sample collected from the patient is measured. Since the CC chemokine receptor/ligand gene such as CCR2 or CCR5 is a good prognostic factor, the higher the expression level of the CC chemokine receptor/ligand gene is, the better the prognosis in the patient is predicted to be.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: December 7, 2021
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Yuya Terashima, Kouji Matsushima, Etsuko Toda, Mikiya Otsuji, Meiji Itakura
  • Patent number: 11180579
    Abstract: An active energy ray-curable composition is disclosed including: an anionically polymerizable compound represented by (1): wherein EWG represents an electron-withdrawing group, X represents a single bond or an oxygen atom (—O—), R represents an n-valent organic group, and n represents an integer of 1 to 6; when n is an integer of 2 to 6, the respective EWG and the respective X may be the same or different; and when n is 1, EWG and R may be bonded; and a compound (photobase generator) represented by (2): wherein ring A represents an aromatic ring that may be substituted or a heteroaromatic ring that may be substituted; R1 and R2 are the same or different and each represents a hydrogen atom or an alkyl group; R1 and R2 may be bonded to each other to form a ring together with an adjacent nitrogen atom; and the ring may be substituted.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: November 23, 2021
    Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, TOAGOSEI CO., LTD.
    Inventors: Koji Arimitsu, Kento Oomura
  • Patent number: 11145863
    Abstract: Provided is the positive electrode active material for a potassium ion battery according to the embodiment comprises a compound represented by Formula (1), in which M represents at least one element selected from the group consisting of V, Fe, Co, Ni, and Mn, and x represents a number from 0 to 1; and is a positive electrode for a potassium ion battery comprising the positive electrode active material for a potassium ion battery according to the embodiment, or a potassium ion battery comprising the positive electrode for a potassium ion battery. KMOxPO4F1-x??[Formula (1)].
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: October 12, 2021
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventors: Shinichi Komaba, Kei Kubota, Kuniko Chihara, Akihiro Katogi