Patents Assigned to Univ.
  • Patent number: 4998535
    Abstract: An instrument for predicting the benefit of using thrombolytic therapy to treat a patient with a heart condition including a first input port for receiving inputs derived from electrocardiograph measurements of the patient's condition, and a processor for computing an estimate of said benefit based upon the electrocardiograph-derived inputs.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: March 12, 1991
    Assignees: Univ. of Washington New England Medical Center Hospitals, Inc., Duke University
    Inventors: Harry P. Selker, Galen S. Wagner, W. Douglas Weaver, Robert M. Califf
  • Patent number: 4999366
    Abstract: A method of controlling hyperlipidemia in mammals which comprises adminstering to a mammal an amount effective to control hyperlipidemia of a compound having hypolipidemic activity and the structural formula: ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different provided both are not hydrogen when R.sup.3 is an alkenyl or cycloalkenyl group, are selected from the group consisting of hydrogen; alkyl of 1 to 18 carbons; substituted alkyl of 1 to 18 carbons; cycloalkyl of 4 to 10 ring carbon atoms; substituted cycloalky of 4 to 10 ring carbon stoms; alkoxy of 1 to 8 carbon atoms; amido; carbamoyl; acyloxy; alkoxycarbonyl; halogen, aryl and substituted aryl, or together R.sup.1 and R.sup.2 from a C.sub.3 to C.sub.7 alkylene group; andR.sup.3 is hydrogen; lower alkyl; substituted lower alkyl; cycloalkyl; substituted cyloalkyl; aryl; substituted aryl; a group --COR.sup.4 were R.sup.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: March 12, 1991
    Assignees: The North Carolina Central Univ., The Univ. of North Carolina at Chapel Hill
    Inventors: Robert A. Izydore, Iris H. Hall
  • Patent number: 4996533
    Abstract: A method and system for mapping ocean currents with a single radar. The radar is a pulsed monostatic radar operating in the HF/VHF range using a single transmitting antenna with a wide beam width. There is a linear array of antennas, each with its own receiver/digitizer system to sample the complex signal. The summing and phasing of the signals is done in software. The correlation functions are calculated using two successive complex Fourier transforms. The current vectors are measured as a function of range and angle from the radar site, thereby generating the current map.
    Type: Grant
    Filed: September 15, 1989
    Date of Patent: February 26, 1991
    Assignees: Univ. of Colo. Foundation, Inc., The United States of America as represented by the Secretary of the Commerce
    Inventors: Peter T. May, Richard G. Strauch, Bob L. Weber
  • Patent number: 4994369
    Abstract: Nucleic acids and peptides are provided which can be used for detecting the status of functional T-lymphocytes as to stimulation and the time of stimulation. The nucleic acids and peptides may be provided by cloning and expression using recombinant techniques. These diagnoses may be used to determine whether T-cells are functional and the degree to which a T-cell population has been stimulated.
    Type: Grant
    Filed: December 15, 1987
    Date of Patent: February 19, 1991
    Assignee: The Board of Trustees of the Leland Stanford Jr. Univ.
    Inventors: Alan M. Krensky, Mark Davis, Thomas Schall, Jan Jongstra
  • Patent number: 4989051
    Abstract: A unitary emitter-detector diode device for direct optical coupling to optical transmission lines as two surface oriental optical fibers on lateral surfaces of the device. The device has a p-n junction formed between a heavily doped semiconducting layer and a lightly doped semiconducting layer and means for guiding and concentrating the recombination of carriers within the diode. The feed through geometry permits transmitting in either direction from the device as well as detecting.
    Type: Grant
    Filed: February 13, 1990
    Date of Patent: January 29, 1991
    Assignees: The Univ. of Delaware, E. I. DuPont de Nemours & Co.
    Inventors: Thomas W. Whitehead, Robert G. Hunsperger, Garfield Simms
  • Patent number: 4988515
    Abstract: An improved amino acid enriched cardioplegic solution adapted for use in preventing and treating heart muscle damage due to regional ischemia. The solution includes a calcium ion concentration of between about 50-300 umol, a metabolizable substrate concentration of 400-1000 mg % and an osmolarity of between about 400-500 mOsmols.
    Type: Grant
    Filed: April 5, 1989
    Date of Patent: January 29, 1991
    Assignee: The Regents of the Univ. of Calif.
    Inventor: Gerald D. Buckberg
  • Patent number: 4980519
    Abstract: An electronic drum has two or more batons, each baton having a transmitter which transmits a distinct radio frequency signal at a position in space. The electronic drum determines the current X, Y, and Z coordinates of each baton transmitter. To determine the position of each baton transmitter, the drum includes a tablet which has a flat support member at a predefined position, with at least two pairs of electrodes coupled to the flat support member. A first pair of the electrodes is shaped so that the amount of capacitive coupling between each baton transmitter and one of the first pair of electrodes corresponds to the position of the baton transmitter with respect to the X axis. A second pair of electrodes is shaped so that the amount of capacitive coupling between each baton transmitter and one of the second pair of electrodes corresponds to the position of the baton transmitter with respect to the Y axis.
    Type: Grant
    Filed: March 2, 1990
    Date of Patent: December 25, 1990
    Assignee: The Board of Trustees of the Leland Stanford Jr. Univ.
    Inventor: Max V. Mathews
  • Patent number: 4977085
    Abstract: A method is provided for expressing the proteases dipeptidyl aminopeptidases A and B which are useful for processing precursor proteins. Genes controlling these proteases may be insdrted into appropriate vectors and transformed into cultures. The proteases may either be utilized to process precursor proteins in vivo or may be extracted from cultures and used to process precursor proteins in vitro.
    Type: Grant
    Filed: February 29, 1984
    Date of Patent: December 11, 1990
    Assignee: The Board of Regents of the Univ. of California
    Inventors: George Sprague, Ira Herskowitz, Jeremy Thorner, David Julius, Lindley Blair, Anthony Brake
  • Patent number: 4977276
    Abstract: Novel heteroarotinoid compositions characterized by the formulae: ##STR1## where: X is S or O; OAc is the acetate group ##STR2## and R is --H, --OH, --OCH.sub.3, or --OC.sub.2 H.sub.5 and includes ##STR3## for formulae (1) and (2). Such compositions exhibit activity as anticancer agents.
    Type: Grant
    Filed: December 28, 1989
    Date of Patent: December 11, 1990
    Assignee: The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges acting for and on behalf of Oklahoma State Univ.
    Inventors: Kenneth D. Berlin, Warren T. Ford, Shirish N. Rajadhyaksha, Jonathan B. Gale, Lyle W. Spruce
  • Patent number: 4972196
    Abstract: A planar antenna is described which comprises a sandwich like structure of a radiating patch, ground plane and transmission feed line. Capacitive means connect the path to the feed line through a rectangular aperture in the ground plane. The energization of the feed line excites radiating modes in both the aperture and the space between the radiating patch and ground plane thereby resulting in an improved impedance bandwidth.
    Type: Grant
    Filed: September 15, 1987
    Date of Patent: November 20, 1990
    Assignee: Board of Trustees of the Univ. of Illinois
    Inventors: Paul E. Mayes, Michael D. Thomas
  • Patent number: 4961958
    Abstract: A process and apparatus that may be used for the production of diamond and doped diamond films at high rates by activated reactive vapor deposition. Carbon is evaporated in a vacuum chamber in the presence of atomic hydrogen containing plasma to form diamond precursors which then deposit on a substrate located within the vacuum chamber. The substrate temperature is maintained at between about 20.degree.-600.degree. C.
    Type: Grant
    Filed: June 30, 1989
    Date of Patent: October 9, 1990
    Assignee: The Regents of the Univ. of Calif.
    Inventors: Chandra V. Desphandey, Rointan F. Bunshah, Hans J. Doerr
  • Patent number: 4950658
    Abstract: This invention relates to a method for improving memory and accompanying symptoms in patients with Alzheimer's disease and related disorders of memory. The method includes the steps of dosing a patient with 2,2-dichlorovinyl dimethyl phosphate sometimes referred to as dichlorvos or DDVP, or a precursor thereof maintaining said dosage at a level and over a period of time sufficient to create a concentration of DDVP in the brain whereby memory improvement occurs. A satisfactory precursor for this method is 2,2,2-trichloro-1-hydroxyethyl dimethyl phosphate sometimes referred to as metrifonate and 1,2-dibromo, 2-dichlorvoethyl dimethyl phosphate sometimes referred to as naled. Other precursors are also useful.
    Type: Grant
    Filed: December 6, 1988
    Date of Patent: August 21, 1990
    Assignee: Board of Trustees of Southern Illinois Univ.
    Inventors: Robert E. Becker, Ezio Giacobini
  • Patent number: 4944689
    Abstract: A molded connector box for connecting electric power delivery wires to a panel (radiant heating) is formed with side walls and a bottom wall. A power wire inlet slot is formed through one side wall and an outlet slot through another side wall. Each slot has a power wire clamping fixture associated therewith. Blade type wire connectors are positioned adjacent to the inlet and outlet openings and a cooperating wire securing element is connected to its adjacent side wall via a strap in a position to be folded into the box and lock into its respective wire connector to hold the wires in the connector. A cover plate snaps into position to close the connector box.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: July 31, 1990
    Assignee: Univ. of British Columbia
    Inventor: Owen R. Carr
  • Patent number: 4943589
    Abstract: This invention is directed to a method for treating helminthiasis which comprises administering to an animal in need thereof an anthelmintically effective amount of a compound of Formula (I): ##STR1## where R.sup.1 is hydrogen or --SR.sup.2,whereinR.sup.2 is hydrogen, --C(O)--CH.sub.3, or ##STR2## or a pharmaceutically acceptable salt thereof. This invention is also directed to a composition for treating helminthiasis in an animal which comprises a pharmaceutically acceptable excipient and an anthelmintically effective amount of a compound of Formula (I). This invention is also directed to novel compounds of Formula (I) wherein R.sup.
    Type: Grant
    Filed: October 27, 1988
    Date of Patent: July 24, 1990
    Assignees: Syntex (U.S.A.) Inc., The Regents of the Univ. of California
    Inventors: Phillip Crews, Thomas R. Matthews, Paul Horton
  • Patent number: 4936823
    Abstract: An implant capsule for insertion into a body canal to apply radiation treatment to a selected portion of the body canal. The device includes a body member defining at least one therapeutic treatment material receiving chamber and at least one resilient arm member associated with the body member for removably engaging the body canal when the device is positioned therein.
    Type: Grant
    Filed: May 4, 1988
    Date of Patent: June 26, 1990
    Assignees: Triangle Research and Development Corp., The Johns Hopkins Univ.
    Inventors: David P. Colvin, Bernard R. Marsh
  • Patent number: 4933022
    Abstract: A solar cell structure having dual metal layer contacts or interdigitated metal contact fingers on one surface is provided with internal bypass diodes in each cell. Each bypass diode comprises doped regions in contact with the metal spaced from the doped regions of the active solar cell. The doped regions of the bypass diodes are of opposite conductivity type from the doped regions of the active solar cell for each contact. The bypass diode is spaced from the active region and is shaded from irradiation during normal operation.
    Type: Grant
    Filed: November 14, 1988
    Date of Patent: June 12, 1990
    Assignee: Board of Trustees of the Leland Stanford Univ. & Electric Power Research Institute
    Inventor: Richard M. Swanson
  • Patent number: 4931158
    Abstract: An apparatus and process for reactive magnetron sputtering wherein film deposition is controlled by placing a grid located over the primary plasma and an auxiliary plasma adjacent to the substrate. The auxiliary plasma is produced using a positively biased d.c. probe. Control of the deposited film properties is provided by varying the d.c. probe voltage and open area of the wire grid.
    Type: Grant
    Filed: August 8, 1989
    Date of Patent: June 5, 1990
    Assignee: The Regents of the Univ. of Calif.
    Inventors: Rointan F. Bunshah, Chandra V. Deshpandey, Aziz A. Karim
  • Patent number: 4927843
    Abstract: The invention relates to novel pharmaceutical compositions which are effective against a wide spectrum of viruses belonging to the Retroviridae family. The active ingredient of the compositions is a thiosemicarbazone compound as herein defined. The compounds are similar to the well-known compound M-IBT (methyl isatin-.beta.-thiosemicarbazone) which has been widely used against smallpox. Contrary to the compounds used according to the present invention, one of which is novel by itself, M-IBT is not effective against viruses of the Retroviridae against which the novel compositions are active.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: May 22, 1990
    Assignee: Ramot Univ. Authority for Applied Res. & Devp. Ltd.
    Inventor: Yael Teitz
  • Patent number: 4924097
    Abstract: A monodisperse aerosol generator forms a stable jet of liquid at a velocity allowing columnar breakup into droplets of uniform size and spacing. To prevent degradation of the monodisperse aerosol, it is disposed by entrainment in a high velocity gaseous stream. To provide an interface for direct injection onto a particle collection device or into an infrared or Raman spectrometer or to interface a liquid chromatograph with a particle collection device or an infrared or Raman spectrometer, the generator is followed by a desolvation chamber operation at about atmospheric pressure and a multistage pressure reducer which evacuates solvent vapor and gaseous medium to form a high momentum, solvent-depleted solute aerosol beam which is input into the infrared or Raman spectrometer.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: May 8, 1990
    Assignees: Georgia Tech RSS. Corp, Univ of Ga Rss. Foundation
    Inventors: Richard F. Browner, James A. de Haseth
  • Patent number: RE33209
    Abstract: An electrical circuit device made in integrated monolithic form has low level operating characteristics of a MOS device and high level operating characteristics of a Triac. The structure includes two double diffused MOS transistors which have merged drain regions. At higher voltage and current levels a lateral Triac structure is triggered by the MOS devices. Alternatively, separate terminal contacts can be made to the P and N regions comprising the MOS transistor source and channel regions with the Triac triggered conventionally by an externally applied control voltage.
    Type: Grant
    Filed: December 5, 1983
    Date of Patent: May 1, 1990
    Assignee: Board of Trustees of the Leland Stanford Jr. Univ.
    Inventor: James D. Plummer