Abstract: In the receive subsystem, the analogue-to-digital converter (40) works on the output of the low-noise amplifier (33), at a chosen rate (F), which corresponds to a bandwidth sampling. The processing stages comprise a custom circuit (5), with * an input memory (510) arranged to contain N successive digital samples, renewed at the chosen rate in blocks of M samples, * a complex digital low-pass filtering function (511, 512), of chosen cut-off frequency, operating on the input memory to supply N filtered digital samples (515), * an M-periodic summing function (531) on the N filtered digital samples, supplying M filtered and summed digital samples (533), * an M?M discrete Fourier transform stage (55), operating on these M filtered and summed digital samples, the digital signals on the M outputs (559) of the Fourier transform representing M separate channels, of width defined by the cut-off frequency of the abovementioned low-pass filter.
Type:
Grant
Filed:
April 10, 2008
Date of Patent:
April 23, 2013
Assignee:
Universite Pierre et Marie Curie (Paris VI)
Inventors:
Olivier Romain, Bruce Denby, Julien Denoulet
Abstract: The invention relates to pharmaceutical compositions using a polypeptide comprising at least one CXXC motif, such as Giardia parasite's variable surface proteins (VSP) or a fragment thereof to raise by oral or mucosal vaccination an immune response against a heterologous selected antigen, such as tumor antigen, microbial antigen or other antigen.
Type:
Application
Filed:
March 29, 2011
Publication date:
April 18, 2013
Applicants:
INSERM (Institut National de la Sante et de la Recherche Medicale), Centre National de la Recherche Scientifique - CNRS, Universidad Catolica de Cordoba (UCC), Assistance Publique Hopitaux de Paris, Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Universite Pierre et Marie Curie (Paris 6)
Inventors:
David Klatzmann, Eliane Piaggio, Hugo Daniel Luján
Abstract: The invention relates to an implant which includes, in order to electrically stimulate a nerve structure, in particular the retina, an electrically insulating substrate (1), a array of recesses (2) formed in an upper surface of the substrate, stimulation electrodes (3) arranged at the bottom of the recesses, and an electrically conductive layer forming a ground plane (4) at the upper portion of the recesses.
Type:
Application
Filed:
April 29, 2011
Publication date:
April 18, 2013
Applicant:
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Inventors:
Henri Lorach, Milan Djilas, Blaise Yvert, Philippe Bergonzo, Gaelle Lissorgues, Lionel Rousseau, Ryad Benjamin Benosman, Serge Picaud, Jose Sahel, Siohoi Ieng
Abstract: The present invention relates to 4S-iota-carrageenan sulfatase and to the use thereof for partially or totally converting the iota-carrageenan into iota-/alpha-carrageenan or alpha-carrageenan. The invention also relates to the method for extracting said enzyme from a Pseudoalteromonas bacteria population or from red marine algae. Finally, the present invention relates to the use of 4S-iota-carrageenan sulfatase to prepare a texturizing agent containing alpha-carrageenan.
Type:
Grant
Filed:
April 22, 2010
Date of Patent:
April 16, 2013
Assignees:
Centre National de la Recherche (CNRS), Universite Pierre et Marie Curie (Paris 6)
Inventors:
Sabine Joncour Genicot, William Helbert
Abstract: A medical gas insufflation device comprising at least a gas outlet circuit, a connector for connecting a pressurized vessel in which the gas is packaged, an expander placed between the connector and the gas outlet circuit, a high-pressure sensor placed between the connector and the expander, a flow meter placed at the outlet from the expander, and a microprocessor connected at least to the sensor to receive signals representative of the pressure observed at the connector and to the flow meter to receive signals representative of the flow rate at the outlet from the expander, wherein the microprocessor includes evaluation means for evaluating the remaining volume of gas after expansion as a function of the signals received from the sensor and the flow meter during a gas expansion operation.
Type:
Grant
Filed:
November 6, 2007
Date of Patent:
April 16, 2013
Assignees:
Sopro, Universite Pierre et Marie Curie-Paris 6'eme
Abstract: The invention relates to a composite material formed by microparticles of magnetic material A and a conductive liquid B. The material is characterized in that the material A is chosen from magnetic compounds and magnetic alloys and is in the form of particles, the mean size of which is between 1 and 10 ?m, and in that the support fluid B is a conductive fluid chosen from metals, metal alloys and salts that are liquid at temperatures below the Curie temperature of the material A, or from mixtures thereof.
Type:
Grant
Filed:
June 26, 2006
Date of Patent:
March 26, 2013
Assignees:
Universite Pierre et Marie Curie, Centre National de la Recherche Scientifique
Abstract: The invention relates to a composite material formed by millimeter-scale particles of magnetic material A and a conductive liquid B. The material is characterized in that the material A is chosen from magnetic compounds and magnetic alloys and is in the form of particles, the mean size of which is between 0.1 and 2 mm, and in that the support fluid B is a conductive fluid chosen from metals, metal alloys and salts that are liquid at temperatures below the Curie temperature of the material A, or from mixtures thereof.
Type:
Grant
Filed:
June 26, 2006
Date of Patent:
March 26, 2013
Assignees:
Universite Pierre et Marie Curie, Centre National de la Recherche Scientifique
Abstract: The present invention provides methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (chimeric RNA).
Type:
Application
Filed:
October 8, 2010
Publication date:
March 14, 2013
Applicants:
ASSOCIATION INSTITUT DE MYOLOGIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Abstract: The invention relates to the use of viral vectors able to stably integrate into the genome of thymic stromal cells, or of intrathymic lymphocytes or lymphocytes precursors, for the manufacture of a medicine intended for intrathymic administration in the frame of the prevention or treatment of genetic immunodeficiencies, acquired immunodeficiencies, or for the induction of immune tolerance of the organism to self or non-self gene products, cells or tissues, or for the prevention or treatment of autoimmune diseases.
Type:
Grant
Filed:
June 3, 2005
Date of Patent:
March 12, 2013
Assignees:
Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Universite Montpellier II
Abstract: The present invention relates to an undergarment (1) comprising: a supporting part (2) which surrounds at least the hips and the top of each thigh; and a flexible collecting bag (10) positioned in the crotch.
Type:
Grant
Filed:
September 12, 2007
Date of Patent:
March 12, 2013
Assignee:
Universite Pierre et Marie Curie (Paris 6)
Abstract: The present invention relates to substrates coated with films comprising compounds of general formula (I) below: and also to the process for manufacturing them and to their use as anode interface layer in electronic devices. The present invention also relates to organic electroluminescent diodes (OLED), polymeric electroluminescent diodes (PLED), organic field-effect transistors (OFET) and organic solar cells (OSC) comprising a substrate according to the invention, to specific organic solar cells and to the process for manufacturing them. Compounds of formula (I) as such also form part of the invention.
Type:
Grant
Filed:
October 13, 2009
Date of Patent:
February 26, 2013
Assignees:
Commissariat a l'Energie Atomique, Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie (Paris 6)
Abstract: A method for controlled reduction of the weight average molar mass of a polysaccharide down to a lower and determined weight average molar mass, which method includes a step for mechanical milling of the polysaccharide by a ball mill, until the polysaccharide having the desired weight average molar mass is obtained.
Type:
Application
Filed:
November 29, 2010
Publication date:
February 7, 2013
Applicants:
CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE - CNRS, INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER-IFREMER, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6 )
Inventors:
Claire Boisset, Tinaig Le Costaouec, Joelle Cozien, Corinne Sinquin, Jacqueline Ratiskol, William Helbert, Gaelle Correc, Veronique Larreta Garde
Abstract: Methods for stimulating an immune response in a mammal by administering a toxin-antigen conjugate are provided. Pharmaceutical compositions and methods for treating an antigen-related state are also described.
Type:
Grant
Filed:
February 13, 2003
Date of Patent:
February 5, 2013
Assignees:
Inserm-Transfert, Universite Pierre et Marie Curie (UPMC)
Abstract: The invention relates to a laser system provided with a laser radiation device (1) in which the radiation frequency is controlled by a heterodyne servo circuit particularly using an interferometric circuit (15). Said interferometric circuit comprises a coil of optical fibres (17) which provide a reference for correcting the laser radiation frequency. To obtain good results in the field of spectral purity, all the elements involved in the laser radiation are fibres and the connections thereof are provided by optical fibres. The invention can be used for lasers requiring high spectral purity.
Type:
Application
Filed:
December 3, 2009
Publication date:
January 24, 2013
Applicants:
Observatoire de Paris, Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Paris 6
Inventors:
Fabien KEFELIAN, Haifeng JIANG, Pierre LEMONDE, Giorgio SANTARELLI
Abstract: A method of making a metal electrode on the surface of a hydrophobic material (7), the method comprising the steps of: [1] bringing one end of a capillary (5) containing a fluid that includes particles of metal dissolved in a solvent close to a zone of the surface of the material (7); and [2] illuminating said zone by means of laser radiation (3) so as to have the effects of causing a drop of fluid to flow from the capillary, of depositing the drop on the zone, of evaporating the solvent contained in the drop, and of annealing the metal particles on the surface of the material in order to form the electrode.
Type:
Application
Filed:
March 24, 2011
Publication date:
January 10, 2013
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Inventors:
Gilgueng Hwang, Dogan Sinan Haliyo, Stéphane Regnier
Abstract: A method of fabricating an elongate structure having a steerable end, the structure including a flexible longitudinal body associated with at least one actuator member having at least one shape memory alloy wire or “SMAW” extending along the body and anchored thereto at its ends, and associated with a mechanism for heating it in controlled manner. The method includes the following steps: inserting at least one of the ends of the SMAW in tubes; crimping the tubes onto the ends of the SMAW; and securing the tubes to the body in such a manner that the wire extends along the body.
Type:
Application
Filed:
March 24, 2011
Publication date:
January 3, 2013
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Abstract: The invention provides a method of fastening lamellae of a lamellar material that is at least partially conductive onto an insulating substrate (2) containing oxides that are suitable for dissociating into mobile ions of given charge and stationary ions of opposite charge, the method comprising the steps of: placing a sample (1) of the lamellar material against a surface of the substrate; causing the oxides of the substrate to dissociate; and subjecting the substrate and the sample to an electric field by means of an electrode in contact with the substrate and an electrode in contact with the sample.
Type:
Application
Filed:
August 2, 2012
Publication date:
January 3, 2013
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Abstract: A method of producing at least one polypeptide from the nuclear genome of Ostreo-coccus sp., the method including introducing at least one recombinant nucleic acid molecule into the nuclear genome of Ostreococcus sp., wherein the recombinant nucleic acid molecule included a first polynucleotide operatively linked to a second polynucleotide, wherein the second polynucleotide encodes at least one polypeptide and wherein the first polynucleotide comprises a promoter sequence allowing expression of the at least one polypeptide in Ostreoccus sp.
Type:
Grant
Filed:
February 8, 2008
Date of Patent:
December 25, 2012
Assignees:
Centre National de la Recherche Scientifique - CNRS, Universite Pierre et Marie Curie
Abstract: The invention relates to a flapping-wing flying vehicle, the vehicle including a frame having two pivots mounted thereon to pivot about two parallel hinge axes (X), each pivot carrying a respective wing, the vehicle including a first oscillation generator for causing the pivots to oscillate in order to cause the wings to flap, said first oscillation generator comprising: two arms (6), each secured to a respective pivot (2); two cranks (9), each hinged to the end of a respective one of the arms about respective axes (X1) parallel to the hinge axes (X) of the pivots; a connecting rod (10) hinged to the ends of the two cranks about axes (X2) parallel to the hinge axes (X) of the pivots; synchronization means (4) for synchronizing the rotation of the two pivots such that the rotations of the pivots are equal and opposite; two electric motors (7), each placed to cause one of the cranks to rotate relative to the associated arm; and control means (50) for controlling and synchronizing the speeds of rotation of the m
Type:
Grant
Filed:
September 16, 2008
Date of Patent:
December 18, 2012
Assignees:
Universite Paris Sud, Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie (Paris 6)
Inventors:
Pascal Martinelli, Thomas Ravasi, Christophe Grand, Stephane Doncieux, Jean-Baptiste Mouret, Emmanuel De Margerie
Abstract: A method of initiating combustion in an internal combustion engine that has a main chamber (5) of variable volume into which an ignitable mixture is introduced, an auxiliary chamber (10) opening out into the main chamber and a controlled valve unit (11, 14, 15) for putting the auxiliary chamber into communication with, or isolating it from, the main chamber. The method includes controlling the controlled valve to put the auxiliary chamber into communication with the main chamber during a period that includes the top dead center between the compression stage and the expansion stage. An engine is specially adapted to implement the method.
Type:
Grant
Filed:
April 7, 2008
Date of Patent:
December 11, 2012
Assignees:
Universite Pierre et Marie Curie (Paris 6), Centre National de la Recherche Scientifique (CNRS)