Abstract: The invention relates to a method for monitoring a reaction and to a reaction system which are inexpensive, compact, easy to implement, and enable the reaction medium to be fully supervised throughout the entire experiment.

Abstract: The invention relates to polymer particles in the form of filaments formed by block copolymers, as well as to the use thereof as rheology modifiers for aqueous or organic solutions. A first aspect of the invention relates to filamentous polymer particles having a length/diameter ratio greater than 100, said particles being formed by block copolymers synthesized by controlled radical emulsion polymerization in emulsion, performed using at least one hydrophobic monomer in the presence of a water-soluble marcoinitiator. The invention is characterized in that the filamentous particles are obtained in an aqueous medium for the synthesis of said block copolymers, performed by heating the reaction medium to a temperature of 60 to 120° C., the final block copolymer containing between 10 and 50 mol. % of the water-soluble macroinitiator and the hydrophobic monomer conversion rate being at least 50%.

Abstract: A musical instrument having strings and a soundboard, wherein the soundboard is excited by the strings by a transducer and is associated with differential stiffening mechanism defining at least two zones of the soundboard that present complementary vibratory behaviors. The two zones are separated by a slot extending along a common boundary between the two zones. The transducer extends across the slot so as to be connected to both zones of the soundboard, such that both zones are excited simultaneously when action is taken on one of the strings.

Abstract: An acoustic power transmitting unit for thermoacoustic systems includes at least one stage provided with at least two thermoacoustic units each of which includes a regenerator or a stack and two heat exchangers, an acoustic resonator including a tube and containing a fluid and in which a magnetic field having high impedance and low-impedance areas is arranged, wherein certain thermoacoustic units are placed in high dimensionless impedance areas. Each high dimensionless impedance area also includes a thermoacoustic unit, wherein two successive thermoacoustic units are always separated by low dimensionless impedance. The resonator includes a reduced diameter section between each couple of successive thermoacoustic units and each cross-sectional narrowing is associated with at least one by-pass which includes a deviation cavity and makes it possible to deviate the major part of a volume flow rate.

Abstract: An inorganic material is described, constituted by at least two elementary spherical particles, each of said spherical particles comprising metallic nanoparticles having at least one band with a wave number in the range 750 to 1050 cm?1 in Raman spectroscopy and containing one or more metals selected from vanadium, niobium, tantalum, molybdenum and tungsten, said metallic nanoparticles being trapped in a mesostructured matrix based on an oxide of an element Y selected from silicon, aluminium, titanium, tungsten, zirconium, gallium, germanium, tin, antimony, lead, vanadium, iron, manganese, hafnium, niobium, tantalum, yttrium, cerium, gadolinium, europium and neodymium. Said matrix has pores with a diameter in the range 1.5 to 50 nm and amorphous walls with a thickness in the range 1 to 30 nm. Said elementary spherical particles have a maximum diameter of 200 microns and said metallic nanoparticles have a maximum dimension strictly less than 1 nm.

Abstract: The present invention relates to a transgenic pig as a model for studying a cone affecting disease, in particular a cone dystrophy or cone-rod-dystrophy, wherein the pig model expresses a dominant negative guanylate-cyclase-2D (GUCY2D) protein, in particular a GUCY2D protein comprising at least one mutation responsible for the appearance of a CORD6 cone dystrophy in a human being. The invention further relates to methods by which the transgenic pig is produced, to uses of said transgenic pig or of one of its elements to identify new biomarkers of a cone affecting disease and/or new compounds for preventing or treating such a disease. Novel methods for preventing or treating a cone affecting disease or for evaluating conditions needed to alleviate such a disease are further herein described.

Abstract: The invention relates to a novel skeletal muscle-specific p57 regulatory element. This element is useful to drive and enhance the specific skeletal muscle expression of therapeutic genes. It is therefore provided nucleic acids and vectors comprising said enhancer element, as well as pharmaceutical compositions comprising the vectors, and uses thereof.

Abstract: Method for producing a microfluidic device comprising a step in which a stamp made of elastomeric material is used for printing a photo-curable and/or heat-curable liquid disposed on a support.

Abstract: A process is described for the preparation of an inorganic material with a hierarchical porosity in the micropore and mesopore domains. The material has at least two elementary spherical particles having a maximum diameter of 200 microns. The process comprises: a) preparing a solution containing zeolitic nanocrystals with a maximum nanometric dimension equal to 60 nm based on silicon and/or precursor elements of proto-zeolitic entities based on silicon; b) mixing, in solution, metallic particles or at least one metallic precursor of metallic particles, a surfactant and the solution obtained in accordance with a) such that the ratio of the volumes of inorganic and organic materials, Vinorganic/Vorganic, is 0.29 to 0.50; c) aerosol atomization of the solution obtained in b) resulting in formation of spherical droplets; d) drying the droplets; g) eliminating the template and surfactant.

Abstract: Inorganic material having at least two elementary spherical particles, each of said spherical metallic particles: a polyoxometallate with formula (XxMmOyHh)q?, where H is hydrogen, O is oxygen, X is phosphorus, silicon, boron, nickel or cobalt and M is one or more vanadium, niobium, tantalum, molybdenum, tungsten, iron, copper, zinc, cobalt and nickel, x is 0, 1, 2 or 4, m is 5, 6, 7, 8, 9, 10, 11, 12 or 18, y is 17 to 72, h is 0 to 12 and q is 1 to 20.

Abstract: The invention relates to polymer particles in the form of filaments formed by block copolymers, as well as to the method for preparing same by means of controlled radical polymerization in emulsion in the presence of a specific living macroinitiator derived from a nitroxide. The invention is characterized in that the filamentous particles are obtained in a dispersed aqueous medium by means of the synthesis of said block copolymers, performed by heating the reaction medium at a temperature of 60 to 120° C., the final block copolymer containing between 10 and 50 mol. % of the macroinitiator which is water soluble and the hydrophobic monomer conversion rate being at least 50%. According to the invention, the weight ratio of hydrophilic fraction of the filamentous particles is less than 25 wt %.

Abstract: The invention relates to an assistance terminal (5, 6a, 6b) including a housing (5) and at least one terminal (6a, 6b) for remotely monitoring a person (1) connected to a medical assistance and/or monitoring device (3).

Abstract: The invention relates to an amphiphilic block copolymer, to the preparation thereof, and to the use thereof in the form of a self-stabilizing latex. The copolymer has the formula R5O—[—CH2CH2—O—]n—C(?O)—CR3R4—[CH2CR6R7]m—S—C(?S)—S—R1 where: R1 is a straight or branched alkyl group, an alkenyl group having one or more —C?C— bonds, or an alkynyl group having one or more —C?C— bonds, said groups including 8 to 18 carbon atoms; 20?n?100; R3 and R4 each are independently H, an alkyl group with 1 to 4 carbon atoms, or a nitrile group, at least one of R3 and R4 being different than H; R6 is a phenyl group or an alkoxycarbonyl group in which the alkoxy group includes 1 to 8 carbon atoms; R7 is a hydrogen atom or a methyl radical; and 20?m?1000.

Abstract: The present invention relates to a novel bacterial strain isolated from groundwater. The invention also relates to bacterial extracts and to the use of same in the context of the treatment of inflammations. More particularly, the present invention relates to novel compositions of interest in the treatment and the prevention of inflammatory disorders, notably dermatological pathologies.

Abstract: The invention relates to a method for treating obesity in a patient, which method comprises administering an effective quantity of ABCG1 inhibitor to a patient in need thereof. The invention further provides an in vitro method for determining whether a patient is at risk of developing obesity, which method comprises detecting the presence of a mutation, substitution or deletion of at least one nucleotide in ABCG1 20 gene or regulatory sequences thereof.

Abstract: A steerable structure of the catheter or endoscope type is disclosed. The structure includes an elastically or deformable longitudinal body including at least one actuator of material of the shape memory type incorporated longitudinally with the body together with a Joule-effect heater enabling the actuator to be contracted longitudinally in order to cause the longitudinal body to bend. The actuator extends over at least one portion of the body that presents varying stiffness.

Abstract: Organic-inorganic hybrid nanofibres comprising two phases: a first mineral phase comprising a structured mesoporous network with open porosity; and a second organic phase comprising an organic polymer, wherein said organic phase is basically not present inside the pores of the structured mesoporous network. A membrane and an electrode comprising said nanofibres. A fuel cell comprising said membrane and/or said electrode. A method of preparing said nanofibres by electrically assisted extrusion (electrospinning).

Abstract: The present invention notably relates to ulvan lyases, to nucleic acid sequences coding for these ulvan lyases, to vectors comprising these coding sequences, to a method of manufacturing these ulvan lyases, as well as to a method of degrading ulvans using these ulvan lyases and applicable applications to the degradation products of the ulvans. The ulvan lyases of the present invention, or ulvanolytic protein, are notably defined as proteins of 30 or 46 kD comprising the following four sequences in their peptide sequence: PNDPNLK, LLEVGNTGTFGSTGS, DLANPDNV and WNLPE.

Abstract: The invention pertains to methods for using chimeric polypeptides of the formula: B-X wherein B represents the B fragment of Shiga toxin or a functional equivalent thereof, and X represents one or more polypeptides of therapeutic significance. Compositions for therapeutic use comprising the polypeptide B-X are also included.

Abstract: The present invention presents new insights in the mechanism of action of the estrogen receptor alpha in breast cancer cells and provides means and tools for modulating said mechanisms of action, thereby influencing the proliferation of estrogen-positive cells such as cancer cells.