Abstract: A calculation computer includes a calculator-solver receiving a working matrix representation corresponding to a system of equations, as well as residue data, and for providing a solution to the system of equations from residue data, an adapter receiving an initial matrix representation corresponding to a system of equations to be processed, as well as a filtering matrix representation, the working matrix representation forced to meet with the initial matrix representation, the adapter iteratively calculates blockwise an intermediate matrix from the initial matrix representation and from said numerical representation of a filtering matrix representation, the calculator-solver works on this intermediate matrix, blockwise, so as to provide a solution of the system of equations of the initial matrix representation, without completely inverting the latter,

Abstract: The invention provides a method of fastening lamellae of a lamellar material that is at least partially conductive onto an insulating substrate (2) containing oxides that are suitable for dissociating into mobile ions of given charge and stationary ions of opposite charge, the method comprising the steps of: placing a sample (1) of the lamellar material against a surface of the substrate; causing the oxides of the substrate to dissociate; and subjecting the substrate and the sample to an electric field by means of an electrode in contact with the substrate and an electrode in contact with the sample.

Abstract: The invention relates to a selective inhibitor of Elk-1 or MSK-1 activation for use in the prevention and/or treatment of mood and anxiety disorders.

Abstract: The present invention relates to at least one protein belonging to the bHLH family and/or at least a nucleic acid molecule coding for the bHLH proteins as drug.

Abstract: The present invention relates to a heterogeneous enzymatic catalyst consisting of a macroprous silica monolith incorporating an enzyme immobilized by means of a compiling agent, to a process for preparing this enzymatic catalyst, to the use of the catalyst for carrying out chemical reactions by continuous flow heterogeneous enzymatic catalyst and to a process of continuous flow heterogeneous enzymatic catalysis using said catalyst.

Abstract: The disclosure relates to a bituminous composition comprising at least one bitumen and at least one organogelling molecule taken alone or as a mixture, said organogelling molecule being represented by the following general formula (I): where: A represents an acyclic, cyclic or polycyclic, saturated or unsaturated, linear or branched hydrocarbon-based group having 3 to 92 carbon atoms, resulting from the polymerization of the side chains of at least one unsaturated fatty acid, X represents an NH group or an oxygen atom O, R1 represents a group chosen from: a linear or branched hydrocarbon-based group having 2 to 40 carbon atoms, optionally comprising one or more heteroatoms and optionally comprising one or more unsaturations, or a substituted or unsubstituted aromatic group, R2 represents a group chosen from: a hydrogen atom, a linear or branched hydrocarbon-based group having 1 to 40 carbon atoms, comprising one or more heteroatoms and optionally comprising one or more unsaturations, or a substituted or unsub

Abstract: The present invention relates to an apparatus for the treatment of a brain affection, which comprises at least one implantable generator (4) made of non-ferromagnetic material comprising a casing (7), an ultrasound generating treating device (11) positioned into said casing to induce brain affection treatment by emission of ultrasound waves, and means for fastening the implantable casing into the skull. The apparatus further comprises a power controller (PwC) to supply electricity to the treating device of the implantable generator and to set and control its working parameters, and connecting means (6) to connect the power controller and the treating device of the implantable generator. A method for treating a brain affection with such an apparatus is also disclosed.

Abstract: The invention relates to a system for electroencephalographic detection of an improper adjustment of a ventilator used on a mammal. The system includes an electroencephalograph, capable of measuring, as a function of time, an electroencephalographic signal representative of a breathing process; and an input for receiving a respiratory initiation signal, different from the electroencephalographic signal, capable of indicating a respiratory initiation time. The detection system further includes means for specifying a beta frequency band comprised between 15 and 30 Hz and with a width comprising between 5 and 10 Hz; means for processing the measured electroencephalographic signal, configured for processing the measured electroencephalographic signal as it is being acquired, in the sole specified beta frequency band; and means for identifying, for each breathing cycle, an improper adjustment of the ventilator from the electroencephalographic signals processed in the sole beta frequency band.

Abstract: Methods for increasing the efficiency of target tissue penetration of an adeno-associated virus (AAV) vector in a patient are provided. In some aspects, the methods involve inhibiting the interaction of the serum protein galectin 3 binding protein (G3BP) with AAV vector. Further provided are methods for reducing tissue distribution of a virus or for neutralizing a virus harbored by an organ destined for transplant, or newly transplanted, by administering a composition comprising G3BP.

Abstract: The present invention relates to a method for culturing adipocytes, in which a homogeneous population of mature adipocytes isolated from adipose tissue is cultured on a three-dimensional culture substrate.

Abstract: The present invention relates to methods to prepare red blood cells (RBCs) for infusion to a patient. Depletion of RBCs with altered deformability is achieved by filtration through micro-bead filters.

Abstract: A device for generating a clock signal, including a phase-locked loop including: a controlled oscillator to deliver a clock signal; plural phase comparators to compare a phase of the clock signal delivered by the controlled oscillator with plural clock signal phases applied at an input of the phase-locked loop; a mechanism for weighted summation of output signals of the plural phase comparators such that one or more of the weighting coefficients applied to one of the output signals has an absolute value that overrides the absolute values of the other weighting coefficients applied to the other output signals; and a mechanism filtering the weighted sum of the output signals of the plural phase comparators, to deliver at an output a control signal to the controlled oscillator.

Abstract: The invention relates to a process for the preparation of an aqueous dispersion of polymer particles in an aqueous medium employing a living macroinitiator requiring a reinitiation temperature of less than 100° C. Application of the particles obtained in the field of surface coatings.

Abstract: A process for depositing a layer on at least part of the surface of a substrate by at least partially submerging the substrate in a solution comprising a solvent and at least one compound intended to form the layer, then drying the substrate, this drying being at least partially carried out in an atmosphere that is isolated from the solution. The submersion in the solution and the drying of the substrate are carried out in the same controlled-atmosphere enclosure.

Abstract: A surgical instrument comprising an elongate body which ends with a tool carrier and which is intended to be introduced into the peritoneal cavity by way of a trocar, the body comprising: an internal tube, which extends along a longitudinal axis of the body and which ends with a bendable stand; an external tube, which extends around the internal tube, coaxially with respect to the internal tube, and which is mounted so as to rotate about the internal tube; the external tube ending with a bellows, which extends around the stand and which, at its end, bears the tool carrier.

Abstract: The present invention relates to a method for treating at least a surface of a substrate containing labile hydrogen atoms to confer to it cytotoxic properties or cell-adhesion properties, characterized in that it comprises at least a step consisting of exposing, within a liquid medium, said substrate or a surface thereof with at least a copolymer, said copolymer containing at least a monomer unit of type A including at least a reactive site able to attach to said substrate or said surface by covalent bonds and at least a monomer unit of type B including at least one molecule able to confer antimicrobial, antiviricidal and/or antifungicidal or cell-adhesion properties to said substrate or said surface, said step being carried out in efficient conditions to promote the covalent grafting of said copolymer to said substrate or a surface thereof.

Abstract: The present invention relates to the use of a transgenic non-human animal, such as a mouse, expressing a reporter gene detectable by a chromogenic, luminescent or fluorescent signal which identifies the cells that express Pw1, or of Pw1-expressing cells or tissues isolated therefrom, as a model for screening a candidate substance for its ability to stimulate adult stem cells, or for monitoring cell aging.

Abstract: System for simulation of a contact with a surface by tactile stimulation comprising a surface (4.1) that will come into contact with the digital pulp of a user's finger (9), said system comprising means of displacing the surface along first and second directions (X, Y) orthogonal to each other and approximately tangent to the digital pulp of the finger (9), said displacement means being controlled as a function of the simulation to be generated, in which said displacement means are electromagnetic actuators (14.1, 14.2).

Abstract: Method for preparing a homogeneous collagen-based material by concentration of a collagen solution, includes bringing a collagen solution into contact by way of continuous injection and use of the material for tissue repair.

Abstract: The invention relates to a semi-conductor transducer, and to the use thereof in an electron donor or electron acceptor space sensor. Said transducer consists of an insulating substrate on the surface of which two electrodes and a semiconductor sensitive element are provided. The sensitive element consists of a layer of a semiconductor molecular material M1 having a conductivity C1 and a layer of a semiconductor molecular material M2 having a conductivity C2 and a forbidden bandwidth Eg2<1 eV. The material layer M1 is in contact with the electrodes. The material layer M2 is deposited on the material layer M1 and is not in contact with the electrodes. The conductivities are such that C2/C1?1.