Abstract: The invention relates to a method for producing a dry film (3), wherein a dry powder mixture is processed into the dry film (3) by a rolling device comprising a first roller (2a) and a second roller (2b). The first roller (2a) has a higher circumferential rotational speed than the second roller (2b), and the dry film (3) is placed on the first roller (2a).

Abstract: The present invention relates to a curable resin composition comprising a curable resin mixture and at least one C2-C3-alkenyl-substituted compound of formula (I) wherein m is 1, 2 or 3; Rm1, Rm2, Rm3 and Rm4 are hydrogen or C6-C14-aryloxy, which is substituted by one or more radicals selected from C1-C24-alkyl and C6-C14-aryl-C1-C10-alkylene; R5, R6, are hydrogen or optionally substituted C6-C14-aryl, or R5 and R6 together are a diradical of the formula A; A is a diradical of the formulae A.1 or A.2 wherein R7 is C2-C3-alkenyl; R8, n are as defined in the claims and in the description. The present invention also relates to a polymer comprising in copolymerized form at least one compound of formula (I) and an organopolysiloxane and to novel compounds of formula (I).

Abstract: A sensor array includes a base for providing a probe signal and a plurality of modular recording sites. Each modular recording site of the plurality of modular recording sites is configured for receiving a signal, for converting the signal into a digital sensor signal and to provide the digital sensor signal to the base. The base is configured for receiving a plurality of digital sensor signals from the plurality of modular recording sites and to process the plurality of digital sensor signals so as to provide the probe signal.

Abstract: A method for increasing privacy of user data of a plurality of users within a dataset is disclosed.

Abstract: Method and Electronic system for non-iterative training of a neural network, based on training data including an input data matrix and an output data matrix, the output data matrix being expected for said input data matrix, the training resulting in a matrix of weights of the neural network.

Abstract: The present application relates to a compound having the formula (I) A-L-B wherein A is represented by (AA), L is a bond or a self-immolative spacer; and B is represented by (BB) or (CC). The compound is capable of releasing molecular cargo in the presence of a reductase and is thus suitable for diagnosing or quantifying the activity of the reductase and for treating, ameliorating, preventing or diagnosing a disorder selected from a neoplastic disorder; atherosclerosis; an autoimmune disorder; an inflammatory disease; a chronic inflammatory autoimmune disease; ischaemia; and reperfusion injury.

Abstract: For improving the sensitivity, lifetime and energy consumption of a dielectric elastomer transducer (1) to be used as a sensor, it is suggested that a dielectric layer (3) enclosed by two electrodes (2) of the transducer (1) includes a nanoscale volume of a fluid (15) such that the dielectric layer (3) is rendered compressible and/or displaceable out of a volume enclosed by the two electrodes (2). The advantage of such a design is that, although the dielectric layer (3) and possible buffer layers (4) separating the electrodes (2) from the dielectric layer (3) may all have thicknesses in the order of a few ?m or even in the sub-?m range, the transducer (1) is rendered highly compliant due to the movability of the fluid (15). In consequence, a large nominal capacitance of the transducer (1) as well as a large relative capacitance change (up to twenty times that of the nominal capacitance) can be achieved in conjunction with a very high sensitivity.

Abstract: In order to determine a rheological property of a fluid, the fluid is conveyed with a constant volume flow rate through a nozzle and the fluid strand thereby generated is deposited on a substrate. A relative movement takes place between the nozzle and the substrate at a forward feed velocity value. A contour of the liquid strand between the nozzle and the substrate is optically measured, and an extensional viscosity as a rheological property is deduced from knowledge of the volume flow rate, the forward feed velocity value and the contour of the fluid strand.

Abstract: The disclosure relates to an audio processing apparatus for localizing an audio source. The audio processing apparatus comprises a plurality of audio sensors, including a primary audio sensor and at least two secondary audio sensors, configured to detect an audio signal from a target audio source, wherein the primary audio sensor defines at least two pairs of audio sensors with the at least two secondary audio sensors; and processing circuitry configured to: determine for each pair of audio sensors a first set of likelihoods of spatial directions of the target audio source using a first localization scheme; determine a second set of likelihoods of spatial directions of the target audio source using a second localization scheme; and determine a third set of likelihoods of spatial directions of the target audio source on the basis of the first sets of likelihoods and the second set of likelihoods.

Abstract: A method for producing non-human conditionally immortalized mast cell progenitors comprises: introducing a nucleic acid molecule comprising an inducible homeobox gene into myeloid progenitor cells, wherein said myeloid progenitor cells are derived from a non-human animal and are engineered to express a heterologous high-affinity IgE receptor alpha subunit (Fc?RI?); and selecting for cells which contain the nucleic acid molecule. The non-human conditionally immortalized mast cell progenitors may be cultured to obtain differentiated mast cells. The mast cells find utility in assays for the determination of IgE mediated allergies.

Abstract: The present invention provides compounds able to induce neuroprotection of damaged neurons and boost the remyelination potential of oligodendrocytes. The compounds have been identified through methods of pharmacological screening of a small molecule library consisting of known pharmacologically active compounds and approved drugs. The screening method is also included in the invention.

Abstract: The present invention relates to an apparatus (12) for processing information by evaluating randomly moving tokens corresponding to particles or quasiparticles, comprising: an input interface (20) for receiving an input signal; a carrier (22) for supporting a plurality of pathways (30) for the randomly moving tokens and at least one join (32) for connecting two pathways and for permitting a passing of a first token in a first pathway of the two connected pathways through the join upon presence of a second token from a second pathway of the two connected pathways in the join; an insertion unit (24) for inserting tokens into the pathways based on the input signal; an excitation unit (26) for applying a stimulus to a token in at least one pathway of the plurality of pathways, said stimulus acting to increase the random movement of the token in a direction substantially parallel to the carrier; and an output unit (28) for providing an output signal based on a location of at least one token after a predefined or d

Abstract: The current disclosure provides methods and composition for treatment of autoimmune and inflammatory conditions, including systemic lupus erythematosus and antiphospholipid syndrome. Certain aspects of the disclosure are directed to methods for treatment of an autoimmune or inflammatory condition comprising administering a composition comprising a therapeutically effective amount of NAPc2 or NAPc2/proline. Further aspects include pharmaceutical compositions comprising NAPc2 or NAPc2/proline and, in some cases, one or more additional anti-inflammatory agents.

Abstract: The present invention relates to a heat-sensitive recording material comprising a carrier substrate, which is black or coloured on at least one side, and a thermoresponsive layer on the at least one black or coloured side of the carrier substrate, wherein the thermoresponsive layer comprises nanoparticles of at least one cellulose ester, and to a method for producing this material, and to a heat-sensitive recording material that can be obtained by this method.

Abstract: The present invention relates to a method for the biological recovery of metals in electric and electronic waste, which comprises a) inoculating a series of iron-oxidizing microorganisms and a mineral medium or fertilizers into an immobilized biomass column; b) performing a stage of biological oxidation of the iron II ions present in said mineral medium or fertilizers to iron III ions; c) irrigating a liquid phase into leaching columns that house an electrical material or one or more printed circuit boards from which metals are to be recovered, the iron III ions being reduced to iron II oxidizing the metals, and separating the metals by means of the dissolution thereof; and d) extracting the metals from the solution. The invention operates under a cyclic process that allows the iron II solution being re-circulated to the biomass column.

Abstract: A method for detecting free metal ions in a sample includes, providing a liquid sample potentially comprising free metal ions. A fluorescent probe comprising an organic fluorescent core and one or more metal binding functional group is added to the sample. The one or more metal binding functional group is selected from a group comprising a phosphonic acid group and an arsonic acid group and is covalently linked to a sp or sp2-carbon atom or a nitrogen atom of the fluorescent core via a P or As atom. A fluorescence of the sample is measured. A presence of the metal ions leads to a concentration-dependent decrease, increase or shift of fluorescence compared to a reference sample. The method preferably involves determining a concentration of the metal ions in the sample. The liquid sample may be a biological sample, such as a bodily fluid, a tissue sample or a sample comprising cells.

Abstract: Disclosed is an apparatus for the sensor-based examination of biological cells, comprising at least one well, wherein the at least one well has (a) an opening; (b) a planar base; (c) at least one sensor for the examination of biological cells, wherein the at least one sensor is arranged on the base of the at least one well; and (d) a medium for cryopreservation, with the medium for cryopreservation comprising biological cells and contacting a surface of the at least one sensor, wherein the medium for cryopreservation, which comprises the biological cells, is present in a frozen state.

Abstract: The present invention is directed to peptidomimetics having antibacterial activity, especially against Gram-negative bacteria. The peptidomimetics of the invention are compounds of the general formula (I), P1-P2-P3-P4-P5-P6-P7-P8-P9-P10-P11-P12-P13-P14-P15-P16 (I) and pharmaceutically acceptable salts thereof, as described in the description and in the claims. The invention is also directed to therapeutic uses of the peptidomimetics for the treatment or prevention of bacterial infections and diseases related to bacterial infections and to non-therapeutic uses of the peptidomimetics for preserving or disinfecting foodstuffs, cosmetics, medicaments or other nutrient-containing materials. In addition, the present invention provides an efficient synthetic process by which these compounds can, if desired, be made in parallel library-format. Moreover, the peptidomimetics of the invention show improved antimicrobial activity, low or no hemolysis of red blood cells and reduced cytotoxicity.

Abstract: An extrusion-based additive manufacturing process including the step of selectively depositing a molten thermoplastic material (P) on a film or sheet made from or containing a polymer blend obtained by melt blending a mixture made from or containing: (A) 60% to 98.8% by weight of a polyolefin; (B) 0.1% to 30% by weight of a compatibilizer; (C) 0.05% to 20% by weight of an amino resin; and (D) 0% to 5% by weight of an additive, wherein the amounts of (A), (B), (C) and (D) are based on the total weight of (A)+(B)+(C)+(D).

Abstract: The present invention provides a solid oral pharmaceutical composition comprising a pharmaceutically effective amount of living microorganisms and one or more pharmaceutically acceptable water absorbing excipient(s), wherein the composition has a water content, determined according to European Pharmacopoeia 9.4, section 2.5.12., from 0.5 to 30% with respect the total weight of the composition. The invention also provides processes for its preparation as well as it use in therapy. The live-cell based composition of the invention is stable at mild conditions.