Abstract: The subject matter of the invention is a method for producing a concrete component (1), wherein a plurality of layers of a dry mixture consisting of at least one silicate former and one hydraulic binder are deposited one atop another on a base (7), wherein after applying each layer the respective layer is mixed with water, wherein the contour of the area that is mixed with water correlates with the desired shape of the concrete component (1) at the level of the respective layer to be applied.

Abstract: An embodiment of the invention relates to a single photon emission system having a proximal end, a distal end, and a single photon emitter located between the proximal end and the distal end; wherein the single photon emission system is adapted to guide optical pump radiation, which is inputted at the proximal end to optically excite the single photon emitter, along a predefined direction that runs from the proximal end to the distal end; and wherein single photons emitted by said single photon emitter, are guided along said predefined direction to the distal end.

Abstract: The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novopapillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novopapillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.

Abstract: The present invention relates to the use of a compound of formula (I) wherein R1 is H, C1-C6-alkyl, phenyl-C1-C4-alkyl or phenyl, R2 is a phenyl group which is substituted with 2 or 3 C1-C6-alkoxy groups and R3 is indolyl or azaindolyl which may carry one or two substituents independently selected from C1-C6-alkyl, C1-C6-alkoxy, phenyl, OH, halogen, NH2, C1-C6-alkylamino, di-C1-C6-alkylamino, heteroaryl with 5 or 6 ring atoms containing 1 or 2 heteroatoms which are independently selected from O, N, and S, or heterocyclyl with 5 or 6 ring atoms containing 1 or 2 heteroatoms which are independently selected from O, N, and S, a physiologically acceptable salt thereof, or a solvate of the compound of formula (I) or of the salt thereof, for the prevention or treatment of leukemia.

Abstract: The present invention relates to a three-dimensional structure of the intracellular domain (AICD) of human amyloid precursor protein (APP695) in complex with human Fe65-PTB2 (i.e. a protein-complex comprising the intracellular domain (AICD) of human amyloid precursor protein (APP695) and the human Fe65-PTB2), as well as to methods and uses of said three-dimensional structure for identifying ligands which modify the interaction between the AICD and the Fe65-PTB2. Moreover, the present invention relates to pharmaceutical compositions which contain one or more of such identified ligands for the prevention or treatment of neurodegenerative disorders.

Abstract: A two-dimensional (2-D) beam steerable phased array antenna is presented comprising a continuously electronically steerable material including a tunable material or a variable dielectric material, preferred a liquid crystal material. A compact antenna architecture including a patch antenna array, tunable phase shifters, a feed network and a bias network is proposed. Similar to the LC display, the proposed antenna is fabricated by using automated manufacturing techniques and therefore the fabrication costs are reduced considerably.

Abstract: The present invention relates to an access method for accessing a protected communication service via a public communication network by means of a secure communication network, whereby the secure communication network is based on user groups, comprising the steps of defining an access group having access to the communication service based on the user groups of the secure communication network, generating a group key for all members of the access group, providing the group key to a member of the access group via the secure communication network, and accessing the communication service via the public communication network using the group key. The present invention further relates to a communication system comprising a secure communication network based on user groups, a public communication network, a protected communication service, and an access server for managing access rights to the communication service, whereby the communication system is adapted to execute the above method.

Abstract: The present invention relates to a method of determining Botulinum toxin (BoNT) based on a luminescence assay. The present application further relates to a peptide that is susceptible to proteolytic cleavage by BoNT which is suitable for that method.

Abstract: The invention relates to a composite system comprising at least one biodegradable blend, containing at least one biodegradable block copolyester urethane (PEU) and also at least one polyhydroxyalkanoate (PHA), possibly a filler comprising a polysaccharide and/or derivatives thereof and also possibly further biocompatible additives. Composite systems of this type are used for producing molded articles, molded parts or extrudates. Furthermore, the invention relates to possibilities for using the composite system.

Abstract: The present invention relates to peptide-mimetic compounds, the synthesis and use thereof fort he inhibition of proteasomes and the induction of apoptosis in tumor cells. The present invention furthermore relates to pharmaceutical compositions comprising the compounds and the use of the compounds for a treatment of diseases, in particular cancer and neurodegenerative diseases.

Abstract: DNA encoding a monomeric variant of red fluorescent protein eqFP611 comprising an amino acid sequence selected from the group consisting of SEQ ID No. 1, SEQ ID No. 3 and SEQ ID No. 5. DNA comprising a nucleotide sequence selected from the group consisting of SEQ ID No. 2, SEQ ID No. 4 and SEQ ID No. 6.

Abstract: The invention relates to methods for coating a substrate with at least one monolayer of self-assembling proteins, using stabilized aqueous solutions with self-assembling proteins, and also to substrates obtainable as a result. Methods for stabilizing solutions with self-assembling proteins, and the stabilized solutions obtainable therefrom, are likewise provided by the invention. According to the coating method, at least one monolayer of a self-assembling protein is produced on a substrate by first providing a stabilized aqueous solution which comprises at least one self-assembling protein.

Abstract: The invention relates to a method for locating an RFID tag (1) using at least one RFID reading device (2). The invention is characterized in that the RFID reading device (2) transmits a query signal (3) which comprises a broadband signal (4); the RFID tag (1) modulates the query signal (3) with a code signal (5) by varying the antenna impedance of the RFID tag and reflects said signal as a reflected signal (6); the RFID reading device (2) receives the reflected signal (6) and obtains the code signal (5) and a scattered broadband signal (7) from the reflected signal; the RFID reading device (2) determines a travel time of the broadband signal (4) by comparing the broadband signal (4) with the scattered broadband signal (7); the RFID reading device (2) determines the distance between the RFID reading device (2) and the RFID tag (1) from the travel time difference.

Abstract: The invention relates to an induction switch comprising a discharge container filled with gas and a coaxially interleaved electrode device, and to a corresponding method for commutating high voltages. The inductive production of a dense plasma and the subsequent flooding of an electrode gap with the plasma ions produced enables the commutation of high currents in the kiloamp range when there are blocking voltages of over 500 kV. Such an induction switch only requires a single discharge gap, can be used over a very wide voltage range, and avoids the problem of electrode erosion as a result of the electrode-free energy coupling.

Abstract: The present subject matter can include a two-dimensional electrochemical writing assembly and uses thereof. The writing assembly can enable for time-dependently displaying of a physical parameter, such as a time-dependent display or recording of the temperature. The writing assembly comprises two different types of electrochemical processors, of which one type is used for controlling the time-dependent switching of the second type of electrochemical processors used in the writing assembly.

Abstract: The present invention is directed to Nogo-A antagonists useful for the control of blood glucose or blood insulin levels in a subject and related use and formulation thereof. In particular, the invention is directed to Nogo-A antagonists useful for the prevention, repression or treatment insulin secretion deficiency and related methods and pharmaceutical formulations. In particular, the invention relates to Nogo-A antagonists useful in the treatment of diabetes mellitus.

Abstract: A measuring method and device for characterizing a semiconductor component (1) having a pn junction and a measuring surface, which has a contacting subarea, covered by a metallization. The method including: A. Planar application of electromagnetic excitation radiation onto the measuring area of the semiconductor component (1) for separating charge carrier pairs in the semiconductor component (1), and B. spatially resolved measurement of electromagnetic radiation originating from the semiconductor component (1) using a detection unit. In one step A, a predetermined excitation subarea of the measuring surface has a predetermined intensity of the excitation radiation and at least one sink subarea of the measuring surface has an intensity of the excitation radiation which is less than the intensity applied to the excitation subarea. The excitation and sink subareas are disposed on opposite sides of said contacting subarea and adjoin it and/or entirely or partially overlap it.

Abstract: Disclosed is a process for the direct alkylation of aromatic compounds with alkanes. To this end a judicious catalyst combination is provided. The composition comprises palladium as a catalytically active metal, and zinc as a promoter, or a metal such as tin having a comparable promoting action. The metals are contained in a zeolite support, or a similar support of a metal organic framework type or a silico alumino phosphate type.

Abstract: An arrangement of floating platforms is provided, including (a) an anchored main platform and (b) one or more outer platforms, each of which being connected to the main platform by at least one connection element. One or more of the main and/or outer platforms are rotatable about a vertical axis by drive units which are fixed thereon. Marine engines having a propeller propulsion system are provided as drive units on the main platform and/or the outer platforms.

Abstract: Specific polymorphisms in BChE gene have been found which allow determining whether a patient suffers from dementia with Lewy bodies (DLB), and allow distinguishing it from Alzheimer's disease. The invention provides an in vitro method for the diagnosis of DLB comprising determining in a biological sample from a subject, the genotype of the following polymorphisms in butyrylcholinesterase (BChE) gene: the polymorphic site at position 3687 in NCBI Accession Number NG_009031 (i.e. SEQ ID NO: 1) the polymorphic site at position 4206 in SEQ ID NO: 1, the polymorphic site at position 4443 in SEQ ID NO: 1. and the polymorphic site at position 68974 in NCBI Accession Number NG_009031 (i.e. position 934 in SEQ ID NO: 26).