Patents Assigned to Universitat
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Patent number: 8497513Abstract: The invention relates to a semiconductor device, in particular to a chemical field effect transistor (ChemFET), a high-electron mobility transistor (HEMT) and an ion-sensitive field effect transistor (ISFET), as well as a method for manufacturing the same. The semiconductor device comprises a structure, the structure comprises a substrate, a first layer comprising GaN and a second layer comprising InAlN, wherein the first and the second layer are arranged parallely to each other on the substrate, and wherein the structure comprises a third layer comprising diamond.Type: GrantFiled: February 26, 2009Date of Patent: July 30, 2013Assignee: Universitat UlmInventors: Erhard Kohn, Michele Dipalo, Farid Medjdoub
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Patent number: 8497085Abstract: Described herein is a method for detecting a wound infection comprising the steps of: contacting a sample obtained from a wound with at least two substrates for at least two enzymes selected from the group consisting of lysozyme, elastase, cathepsin G and myeloperoxidase, and detecting a wound infection when a conversion of the at least two substrates with said at least two enzymes are determined.Type: GrantFiled: November 17, 2011Date of Patent: July 30, 2013Assignees: Technische Universitat Graz, Forschungsholding Tu Graz GmbH, Medicinische Universitat GrazInventors: Georg Gübitz, Eva Wehrschütz-Sigl, Andrea Hasmann, Barbara Binder, Michael Burnett, Michael Schintler
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Publication number: 20130186078Abstract: The present invention relates to a micro-valve which is formed from two firmly connected substrates and preferably has an actuator element, for example that is diaphragm-driven, for the controlled opening and closing of a first and/or second passage. The invention further relates to a method for producing such a micro-valve and to a micro-pump which uses at least one such micro-valve. Said micro-pump is intended to be used in particular in conjunction with the development of an artificial sphincter. The micro-valve has a first substrate and a second substrate which are non-detachably joined to each other in order to form a controllable fluid flow section, and at least one first passage and at least one second passage. According to the invention, the micro-valve has at least one elastically deformable seal structure which, for example, can be formed by a photostructurable silicone, to seal off the first and/or second passage.Type: ApplicationFiled: April 7, 2011Publication date: July 25, 2013Applicant: ALBERT-LUDWIGS-UNIVERSITAT FREIBURGInventors: Thomas Lemke, Peter Woias, Jens Kiöker, Frank Goldschmidtooing
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Publication number: 20130189696Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence.Type: ApplicationFiled: March 18, 2013Publication date: July 25, 2013Applicants: DRK BLUTSPENDEDIENST WEST GMBH, ERNST-MORITZ-ARNDT-UNIVERSITAT GREIFSWALDInventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
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Publication number: 20130189745Abstract: The present invention relates to an in vitro produced, artificial cellulosome for enzymatic breakdown of resilient substrates. In particular, the present invention provides a complex having an increased activity on resilient substrates, such as crystalline cellulose. The in vitro formed complex comprises a backbone scaffold having at least four binding sites capable of binding the enzyme components, whereby at least two of the binding sites have essentially the same binding specificity; and at least three different enzyme components being randomly bound to the at least four binding sites. Method for preparing the complex and uses of the same for enzymatic breakdown of resilient substrates are also provided.Type: ApplicationFiled: July 19, 2011Publication date: July 25, 2013Applicant: Technische Universitat MunchenInventors: Wolfgang H. Schwarz, Jan Krauss, Vladimir V. Zverlov, Daniel Hornburg, Daniela Köck, Louis-Philipp Schulte
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Publication number: 20130189725Abstract: The present invention relates to a human in vitro model system of the blood cerebrospinal fluid barrier (BCSFB), to a method for producing said model system, as well as to uses thereof.Type: ApplicationFiled: August 17, 2011Publication date: July 25, 2013Applicant: RUPRECHT-KARLS-UNIVERSITAT HEIDELBERGInventor: Horst Schroten
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Publication number: 20130189363Abstract: ?-Hairpin peptidomimetics of the general formula Cyclo (-Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11-Xaa12-Xaa13-Xaa14-), enantiomers and pharmaceutically acceptable salts thereof, with Xaa1-Xaa14 being amino acid residues of certain types which are defined in the description and the claims, have anti-infective activity, e.g. to selectively inhibit the growth of or to kill microorganisms such as Bacillus subtilis and/or Shigella boydii. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.Type: ApplicationFiled: August 5, 2010Publication date: July 25, 2013Applicants: UNIVERSITÄT ZÜRICH, POLYPHOR AGInventors: Daniel Obrecht, Frank Otto Gombert, John Anthony Robinson, Krystyna Patora-Komisarska
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Publication number: 20130188131Abstract: It is applied to bifocal, multifocal or progressive intraocular lenses or contact lenses, multifocal corneal ablation or other multifocal configurations, comprising means for projecting the image of a point light source on the retina of a patient and an assembly for directly recording the light reflected in said retina after the double passage of the light through the ocular means, integrating a first focus corrector device inserted in the path of the light beam guided towards the retina and a second focus correction device inserted in the light beam reflected from the retina, to be guided towards the mentioned recording means, each of said focus correction devices having independent control means for controlling the operation thereof.Type: ApplicationFiled: May 3, 2011Publication date: July 25, 2013Applicant: UNIVERSITAT POLITÈCNICA DE CATALUNYAInventors: Jaume Pujol Ramo, Sergio Òscar Luque, Fernando Díaz Doutón
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Publication number: 20130190367Abstract: Compounds of formula (I) or their pharmaceutically acceptable salts, or their stereoisomers or mixtures of stereoisomers, where: R1 is selected from the group consisting of: phenyl, and phenyl mono-, di-, or tri-substituted by a radical independently selected from the group consisting of F, Cl, Br, I, (C1-C6)-alkyl, COO-(C1-C6)-alkyl, and (C1-C6)-alkoxy; and R2 is a radical selected from the same group as R1, further including a phenyl substituted in 4-position by a radical independently selected from the group consisting of —O(CH2)CONH(CH2)3CH3 and OCH2COOC(CH3)3, a biphenyl-4-yl, thiazol-2-yl, and a thiazol-2-yl mono- or di-substituted by a radical selected from F and phenyl; inhibit cell proliferation of tumor cells independently of p53 protein and may also induce apoptosis in several tumor cells independently of p53 protein, being useful for the treatment of several types of cancer.Type: ApplicationFiled: August 29, 2011Publication date: July 25, 2013Applicants: UNIVERSITAT DE BARCELONA, FUNDACIO PRIVADA INSTITUT DE RECERCA BIOMEDICA DE BARCELONA, FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE, FUNDACIO PRIVADA PARC CIENTÍFIC DE BARCELONAInventors: Joan Gil Santano, Rodolfo Lavilla Grífols, Fernando Albericio Palomera, Alba Pérez Perarnau, Sara Preciado Gallego, Diana Mª González Gironès, Daniel Iglesias Serret, Rosario Ramón Albalate
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Publication number: 20130187595Abstract: The invention relates to a circuit for a system for contactless, inductive power transmission, in particular for use in supplying power to mobile devices, and to an associated charging circuit. The circuit comprises a primary-side circuit, which is disposed on a primary side and can be connected to a primary-side supply voltage, and a secondary-side circuit, which is disposed on a secondary side and can be connected to a load to be supplied with power. Furthermore a transformer stage having galvanic isolation is provided for the contactless transfer of power from the primary side over an air gap to the secondary side, wherein at least two magnetically coupled coils are provided for inductive power transmission and can be spatially separated from one another by distancing the secondary side from the primary side. The transformer stage has a resonant converter and the secondary-side circuit further comprises a restabilisation stage.Type: ApplicationFiled: May 27, 2011Publication date: July 25, 2013Applicants: Friedrich-Alexander-Universitat Erlangen-Nurnberg, Friwo Geratebau GMBHInventors: Alexander Bucher, Thomas Durbaum
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Publication number: 20130189676Abstract: The invention relates to an in vitro method for predicting disease risks, progression of diseases, drug risks, success of treatment and for finding drug targets by looking for one or more genetic modifications in the promoter region of the CHK1 (CHEK1) gene on human chromosome 11q23, the genetic modifications being a substitution thymine for guanine in position ?1143 in the promoter of CHK1, of thymine for cytosine in position ?1400, a substitution of cytosine for thymine in position ?1453 or an insertion of one cytosine in position ?1454 and the genetic modifications being detected individually or in any combinations by way of known methods.Type: ApplicationFiled: November 1, 2012Publication date: July 25, 2013Applicant: Universitat Duisburg-EssenInventor: Universitat Duisburg-Essen
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Patent number: 8491766Abstract: The invention at hand concerns a novel class of gas sensors, in particular for hydrogen or hydrogen-containing fluids (gases or liquids), such as hydrocarbons, hydrogen sulphides or more complex gas mixtures or gas compositions which contain hydrogen or hydrogen compounds.Type: GrantFiled: November 29, 2006Date of Patent: July 23, 2013Assignee: Justus-Liebig-Universitat GiessenInventors: Baker Farangis, Bruno K. Meyer, Hans-Peter Jorde, Jennifer Stiebich
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Patent number: 8495492Abstract: Systems, methods, and apparatus are provided for distributed augmentation. In one implementation, a system is provided. The system includes one or more presentation applications, each presentation application operable to provide a presentation output and a plurality of augmentation and presentation control (iAPC) modules operable to provide user augmentations of the presentation output. The system also includes one or more distributed augmentation and presentation management (DAPm) modules operable to separately manage augmentations from the presentation output and to provide an augmented presentation output and one or more display devices for presenting the augmented presentation output.Type: GrantFiled: March 14, 2007Date of Patent: July 23, 2013Assignee: Technische Universität DarmstadtInventors: Eberhard Max Mühlhäuser, Christoph Trompler, Georg Turban
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Patent number: 8492106Abstract: The transporter that translocates ergothioneine has been identified. Described are methods for identifying and obtaining compounds capable of modulating ergothioneine transport as well as the use of such compounds for the treatment of diseases ergothioneine may be involved in such as autoimmune diseases, in particular rheumatoid arthritis, as well as other diseases arising from cell damage caused by radiation, radicals and relative oxidant species. Furthermore, diagnostic means and methods for determining the presence or susceptibility to such a disease are provided.Type: GrantFiled: May 24, 2005Date of Patent: July 23, 2013Assignee: Universitat Zu KolnInventors: Dirk Gründemann, Edgar Schömig
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Publication number: 20130182949Abstract: In summary, the present invention relates to a method for analyzing and/or testing at least one user interface, comprising the steps of: transmitting an address of at least one user interface, in particular a web-based user interface, and/or a source code together with the associated graphical elements of at least one user interface, in particular a web-based user interface, to an evaluation apparatus (10); transmitting the address of the at least one user interface and/or the source code together with the associated graphical elements of the at least one user interface to at least two differently configured presentation apparatuses (12, 14); generating at least one pixel image of the user interface on each presentation apparatus (12, 14); transmitting each generated pixel image to the evaluation apparatus (10); automatically determining and/or representing at least one difference between the generated pixel images of the at least one user interface.Type: ApplicationFiled: February 3, 2009Publication date: July 18, 2013Applicant: Universitat Karlsruhe (TH)Inventor: Viktor Pankratius
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Publication number: 20130184565Abstract: A hyperpolarized liquid contrast agent is for use in a MRT device. The liquid contrast agent passes through a conduit of a MW resonator in the magnetic field of the MRT device. A microwave with a frequency of at least 40 GHz couples into the MW resonator for polarizing the liquid contrast agent upon passage through the conduit in the MW resonator using DNP. The contrast agent is polarized in a continuous passage in the MW resonator and administered immediately. A MW mode is formed in the MW resonator which has an antinode in the magnetic field strength and a node in the electric field strength. The power of the introduced microwave and coupling of the microwave into the resonator are adjusted such that in the area of the line, an amplitude of the MW magnetic field strength B1?1.5·10?2 Ts 1/T1,e results, wherein T1,e is the relaxation time of the DNP-active electrons.Type: ApplicationFiled: December 20, 2012Publication date: July 18, 2013Applicant: Johann Wolfgang Goethe-Universitat Frankfurt am MainInventor: Johann Wolfgang Goethe-Universitat Frankfurt am Main
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Publication number: 20130183527Abstract: The present invention relates to a process for obtaining nanocrystalline corundum, characterised in that it comprises a first step of thermal treatment of the raw material used in the process at standard pressure, to a temperature greater than that of the last endothermic accident of the differential thermal analysis record of the raw material, performed to 925° C.; and a second step of fast cooling from the maximum temperature reached in the preceding step to room temperature. Moreover, the present invention relates to the nanocrystalline corundum obtainable from the process described, as well as to multiple uses of said corundum. Furthermore, this material may be disaggregated, for example by means of high-energy grinding, to produce a fine aggregate that may be used as an abrasive or as a functional load in plastic polymers or other types of materials.Type: ApplicationFiled: August 3, 2011Publication date: July 18, 2013Applicant: UNIVERSITAT DE VALENCIAInventors: Joaquín Bastida Cuairán, Rafael Ibañez Puchades, Maria del Mar Urquila Casas, Pablo Rafael Pardo Ibañez
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Publication number: 20130182464Abstract: The present invention relates to an electronic circuit with which input voltages at an input of the circuit are converted into higher output voltages at an output of the circuit, whereby the voltage conversion already starts at low voltages at the input. According to the present invention, the DC converter circuit for the generation of an output voltage from an input voltage (Vin) comprises a transformer (Tr) with a first primary winding (1) that can be connected to the input voltage (Vin) via a first transistor (T1) that is connected in series, and a second primary winding (2) that can be connected to the input voltage (Vin) via a second transistor (T2) that is connected in series.Type: ApplicationFiled: December 20, 2012Publication date: July 18, 2013Applicant: ALBERT-LUDWIGS-UNIVERSITAT FREIBURGInventor: Albert-Ludwigs-Universitat Freiburg
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Publication number: 20130184733Abstract: A device for repeated piercing of an organic tissue and method thereof are disclosed. The device may comprise an arrangement of application tools each of which is connected to an operating mechanism and has a distal tool end which is formed for at least one application tool with a penetration device, whereby by way of the operating mechanism the tools can be displaced relative to each other between an initial position and a penetration position. During the relative movement, the effect direction of an application force provided by at least one application tool is counter to the effect direction of the application force provided by the other application tool. A mechanical actuation device, which is connected to the operating mechanism, is suitable for repeatedly effecting the relative displacement of the at least one application tool between the initial position and the penetration with an operating frequency.Type: ApplicationFiled: January 11, 2013Publication date: July 18, 2013Applicant: TECHNISCHE UNIVERSITAT BERLINInventor: TECHNISCHE UNIVERSITAT BERLIN
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Patent number: 8488851Abstract: The invention relates to a system and method for measuring light diffusion in the eyeball or eye region, by recording and processing retinal images. The inventive system includes a double-pass ophthalmoscopic system having means for correcting low-order aberrations. Said system can be used to record images of the plane of the retina on a CCD camera, the outer part of said images containing information relating to ocular scattering. The aforementioned images can be used to obtain the objective scattering index (OSI), providing the ratio between the energy on the outer part of the image and the energy in the central part, or, alternatively, the modulation transfer function (MTF) area can be used for this purpose once the low frequencies have been filtered. According to the inventive method, the low-order aberrations are corrected before a retinal image or a temporal sequence of retinal images is captured and recorded.Type: GrantFiled: May 5, 2008Date of Patent: July 16, 2013Assignee: Universitat Politecnica de CatalunyaInventors: Pablo Artal Soriano, Jaume Pujol Ramo, Sergio Oscar Luque, Antonio Benito Galindo, Guillermo Pérez Sanchez