Patents Assigned to Universite de Franche-Comte
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Patent number: 9669080Abstract: The invention relates to a peptide of 15 to 20 amino acids deriving from TERT protein, which peptide is capable of (i) binding to HLA class II and (ii) stimulating a CD4 Th response. These universal cancer peptides are especially useful in anti-tumor immunotherapy and immunomonitoring.Type: GrantFiled: March 7, 2013Date of Patent: June 6, 2017Assignees: INVECTYS, Universite De Franche-Comte, Centre Hospitalier Regional Universitaire De BesanconInventors: Pierre Langlade Demoyen, Olivier Adotevi, Magalie Dosset
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Patent number: 9666786Abstract: A bulk wave piezoelectric resonator operating at a predetermined frequency includes a substrate block, having a plane face, a first thickness and consisting of a first material, a resonant plate having a length, width and second thickness, and consisting of a second piezoelectric material, first and second metal electrodes at least partly covering the resonant plate on each side and partly facing each other. The resonant plate is fixed perpendicularly in the vicinity of the plane face of the substrate block so that the width of the resonant plate and the first thickness of the substrate block have the same direction, and the first material, the second material, the first thickness of the block of substrate, the length, the width, the second thickness of the resonant plate are configured for trapping bulk waves at the operating frequency of the resonator and for producing a plane-plane type bulk wave piezoelectric resonator.Type: GrantFiled: October 5, 2012Date of Patent: May 30, 2017Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE-COMTE, ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUESInventors: Sylvain Ballandras, Gwenn Ulliac, Blandine Edouard-Guichardaz, Thomas Baron, Jean-Yves Rauch
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Patent number: 9632121Abstract: The present invention relates to electronic power converter suitable, in a first mode, for receiving electrical voltage and/or current magnitudes from a first device as input, for processing them using processing means capable of measuring said electrical magnitudes and servocontrolling said electrical magnitudes based on said measurements and constraints specific to a second device, and for providing the adapted voltage and/or current magnitudes to said second device.Type: GrantFiled: May 15, 2012Date of Patent: April 25, 2017Assignees: CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE-COMTEInventors: Daniel Depernet, Oumar Ba, Alain Berthon
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Patent number: 9496847Abstract: A piezoelectric and ferroelectric bulk wave transducer operating at a predetermined frequency includes a block of substrate, having a first thickness and in a first material, and a piezoelectric and ferroelectric transduction plate, having a length, a width and a second thickness, and in a second piezoelectric material, first and second metal electrodes covering the plate in the direction of the length thereof. The plate has first and second ferroelectric domains with alternating polarizations, distributed along the length of the plate according to a periodic pattern of pitch. The plate is attached perpendicularly to the block so that the width of the plate and the first thickness of the block are the same direction. The first and second material, the first thickness of the block, the length, the width, the second thickness, the pitch of the plate are configured for generating and trapping bulk waves at the operating frequency of the transducer, guided between both electrodes.Type: GrantFiled: October 5, 2012Date of Patent: November 15, 2016Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE DE FRANCHE-COMTEInventors: Sylvain Ballandras, Gwenn Ulliac, Blandine Edouard-Guichardaz, Florent Bassignot, Emilie Courjon
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Patent number: 9488962Abstract: The invention relates to an alkali-metal vapor cell, especially for an atomic clock, and to its manufacturing process.Type: GrantFiled: October 11, 2013Date of Patent: November 8, 2016Assignees: Centre National de la Recherche Scientifique—CNRS, Universite de Franche ComteInventors: Nicolas Passilly, Christophe Gorecki, Ravinder Chutani, Rodolphe Boudot
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Patent number: 9459156Abstract: This temperature sensor includes an HBAR resonator, a unit for determining the difference between two distinct resonance frequencies at a temperature T, measured between two electrodes of a same pair of the HBAR resonator and a unit for determining the temperature of the resonator from the difference in frequencies and from a one-to-one function providing the match between the temperature and the frequency difference. The resonator is formed by a stack of a first electrode, a transducer, a second electrode, and acoustic substrate and the cuts of the transducer and of the substrate are selected so as to obtain high electro-acoustic couplings and a difference in frequency temperature sensitivities between two distinct vibration modes co-existing within the resonator, greater than or equal to 1 ppm·K?1.Type: GrantFiled: January 18, 2012Date of Patent: October 4, 2016Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE FRANCHE-COMTEInventor: Sylvain Jean Ballandras
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Patent number: 9246472Abstract: The invention relates to an acoustic volume wave resonator including a mounting, a resonating substrate, and a diaphragm. The mounting comprises an internal cavity and an internal electrode, so as to form a gap area between the internal electrode and a portion of the diaphragm. The resonating substrate is configured to generate longitudinal mode acoustic waves vibrating at the work frequency of the resonator, when an electrostatic field having a sinusoidal component at a work frequency is generated in the gap area by applying a differential voltage between the diaphragm or the first surface of the resonating substrate on the one hand and the internal electrode on the other hand.Type: GrantFiled: July 6, 2012Date of Patent: January 26, 2016Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE-COMTEInventors: Bernard Dulmet, Mihaela Ivan, Sylvain Ballandras
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Patent number: 9180594Abstract: The present invention relates to a tool for a microtechnical gripper. The tool of the invention includes a tip having a support and first and second fingers disposed opposite one another in a chosen position. Each finger is connected to the support by a connecting element so as to be held in a rest position corresponding to the chosen position, the connecting element being flexible in order to allow the fingers to move with at least one degree of freedom relative to the support.Type: GrantFiled: May 24, 2012Date of Patent: November 10, 2015Assignees: Centre National De La Recherche Scientifique CNRS, Universite De Franche-ComteInventors: David Heriban, Joël Agnus
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Publication number: 20150283219Abstract: The invention relates to a peptide of 15 to 20 amino acids deriving from TERT protein, which peptide is capable of (i) binding to HLA class II and (ii) stimulating a CD4 Th response. These universal cancer peptides are especially useful in anti-tumor immunotherapy and immunomonitoring.Type: ApplicationFiled: March 7, 2013Publication date: October 8, 2015Applicants: INVECTYS, Universite De Franche-Comte, Centre Hospitalier Regional Universitaire De BesanconInventors: Pierre Langlade Demoyen, Olivier Adotevi, Magalie Dosset
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Publication number: 20150158120Abstract: According to one aspect, the invention relates to a device (1, 2, 3) for laser nanomachining a sample made of a material having a given transparency band, the device comprising: a focusing module (203, 703) allowing a nondiffracting beam (210, 710) to be generated, along a focusing line generally oriented along the optical axis of the focusing module, from a given incident beam; first means (202, 702) for emitting a first light pulse (I1) of spectral band comprised in the transparency band of said material, able to generate in said material, after focusing by said focusing module, a plasma of free charges along said focusing line via multiphoton absorption, thus forming a “plasma channel”; and second means (202, 702) for emitting at least one second electromagnetic wave (I2) of spectral band comprised in the transparency band of said material, which wave(s) is/are intended to be spatially superposed on said plasma channel in order to heat said material via absorption by the free charges of the plasma.Type: ApplicationFiled: April 12, 2013Publication date: June 11, 2015Applicants: Université de Franche-Comté, Centre National de la Recherche Scientifique-CNRSInventors: François Courvoisier, Pierre-Ambroise Lacourt, Maxime Jacquot, Luca Furfaro, John Dudley, Michel De Labachelerie
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Patent number: 9052218Abstract: A microtechnique device includes an actuator, designed to move movable equipment with a permanent magnet with respect to a support. The actuator is designed to move the movable equipment in two degrees of freedom from a position of rest, and the permanent magnet is chosen to have a magnetic field distribution that presents a main plane of symmetry and a main direction of magnetization passing through a center. The device includes a first magnetic sensor and a second magnetic sensor, these two being designed to detect a movement of the magnet. The sensors are positioned with respect to the position of rest of the magnet in a specific manner in the main plane of symmetry of the magnetic field and near to extrema. The first and second sensors are then sensitive to the movements of the movable equipment perpendicular to their respective working axes.Type: GrantFiled: January 17, 2011Date of Patent: June 9, 2015Assignees: UNIVERSITE DE FRANCHE COMTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUESInventors: David Heriban, Joël Agnus, Ronan Noizet
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Patent number: 8992613Abstract: The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.Type: GrantFiled: July 1, 2010Date of Patent: March 31, 2015Assignees: Universite de Franche-Comte, Centre Hospitalier Universitaire de BesanconInventors: Philippe Humbert, Delphine Binda, Celine Viennet-Steiner, Sophie Robin, Helene Tauzin, Gwenael Rolin, Lionel Pazart
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Publication number: 20150054520Abstract: A micropositioning device for a piezoelectric actuator includes a means for controlling an electric field applied to the piezoelectric actuator so as to deform the piezoelectric material, and means for simultaneous measurement of a variation of electric charge accumulated on the piezoelectric actuator resulting from the deformation; and means for acquiring measurements of the variation of electric charge, for processing these acquisitions and for estimating a displacement (x, y, z) of the piezoelectric actuator and/or an applied force.Type: ApplicationFiled: March 22, 2013Publication date: February 26, 2015Applicants: Universite De Franche Comte, Ecole Nationale Superieure De Mecanique Et Des MicrotechniquesInventors: Ioan Alexandru Ivan, Joël Agnus, Manitrarivo Rakotondrabe
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Patent number: 8922095Abstract: A transponder including a first resonator and a series of one or more second resonators with coupling of evanescent waves exhibiting at least one first resonant mode and one second resonant mode, said first resonator being connected via a first port, to a first means allowing an interrogation, wherein said second resonators are connected via at least one second port, to at least one variable load element capable of modifying coupling conditions of the resonant modes and consequently a response measured on said first port.Type: GrantFiled: October 8, 2010Date of Patent: December 30, 2014Assignees: Senseor, Centre National de la Recherche Scientifique -CNRS, Universite de Franche ComteInventors: Sylvain Ballandras, William Daniau, Jean-François Leguen
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Publication number: 20140292137Abstract: The subject matter here is an actuation device (1) comprising an actuation element (3) including a fixed portion (31) and a driving portion (32); wherein the fixed portion (31) includes a crawling surface (311), the driving portion (32) includes a flexible moveable blade (321) positioned in parallel and at a distance from the crawling surface (311), and wherein, when a power supply voltage is applied between the moveable blade (321) and the crawling surface (311), the free end (3211) comes into contact with the crawling surface (311), and a contact area, between the moveable blade (321) and the crawling surface (311), increases by propagation of the crawling front (3213) along the moveable blade (321), the propagation of the crawling front displacing the moveable blade (321) according to a first orientation.Type: ApplicationFiled: November 26, 2013Publication date: October 2, 2014Applicants: SILMACH, UNIVERSITE DE FRANCHE-COMTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Patrice Le Moal, Gilles Bourbon, Patrice Minotti, Paul Vescovo
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Publication number: 20140292155Abstract: A piezoelectric and ferroelectric bulk wave transducer operating at a predetermined frequency includes a block of substrate, having a first thickness and in a first material, and a piezoelectric and ferroelectric transduction plate, having a length, a width and a second thickness, and in a second piezoelectric material, first and second metal electrodes covering the plate in the direction of the length thereof. The plate has first and second ferroelectric domains with alternating polarizations, distributed along the length of the plate according to a periodic pattern of pitch. The plate is attached perpendicularly to the block so that the width of the plate and the first thickness of the block are the same direction. The first and second material, the first thickness of the block, the length, the width, the second thickness, the pitch of the plate are configured for generating and trapping bulk waves at the operating frequency of the transducer, guided between both electrodes.Type: ApplicationFiled: October 5, 2012Publication date: October 2, 2014Applicants: UNIVERSITE DE FRANCHE-COMTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)Inventors: Sylvain Ballandras, Gwenn Ulliac, Blandine Edouard-Guichardaz, Florent Bassignot, Emilie Courjon
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Patent number: 8829764Abstract: The invention relates to a resonator of the harmonic bulk acoustic resonator HBAR type, comprising a piezoelectric transducer (6) clamped between two electrodes (4, 8) with a strong electroacoustic coupling, cut according to a first cutting angle ?1, and an acoustic substrate (10) with a working frequency acoustic quality coefficient at least equal to 5·1012, cut according to a second cutting angle ?2 with at least one shearing vibration mode. The transducer and the substrate are arranged in such a way that the polarization direction of the shearing mode of the transducer and the polarization direction of the shearing of the substrate are aligned, and the second cutting angle ?2 is such that the temperature coefficient of the frequency of the first order CTFB1 corresponding to the shearing mode and to the second cutting angle ?2 is zero with inversion of the sign thereof on either side of, or equal to, a bias.Type: GrantFiled: May 29, 2009Date of Patent: September 9, 2014Assignees: Universite de Franche Comte, Centre National de la Recherche Scientifique (C.N.R.S.)Inventors: Sylvain Ballandras, Dorian Gachon
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Patent number: 8810106Abstract: The invention relates to a resonator of the high bulk acoustic resonator HBAR type, for operating at a pre-determined working frequency, comprising: a piezoelectric transducer (6), an acoustic substrate (10), a counter-electrode (8) formed by a metal layer adhering to a first face of the transducer (6) and a face of the acoustic substrate (10), and an electrode (4) arranged on a second face of the transducer (6) facing away from the first face of the transducer (6) and the substrate (10).Type: GrantFiled: May 29, 2009Date of Patent: August 19, 2014Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite de Franche ComteInventors: Sylvain Ballandras, Dorian Gachon
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Patent number: 8802307Abstract: A process for the production of dihydrogen from hydrogenated silicon by bringing the hydrogenated silicon into contact with an alkaline solution. Devices of the fuel cell type using this hydrogen production method are also described.Type: GrantFiled: May 2, 2008Date of Patent: August 12, 2014Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite de Franche-ComteInventor: Bernard Gauthier-Manuel
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Patent number: 8729982Abstract: The elementary filter of the HBAR type includes two resonators (20, 22) of the HBAR type which are each formed by a transducer (8) and a substrate (12) which are coupled in a suitable manner by electroacoustic waves. The first resonator (20), the second resonator (22) and the coupling element (28) by way of evanescent waves include the same monobloc acoustic substrate (12) which is arranged facing and coupled to the piezoelectric transducer (8) by waves having the same longitudinal or transverse vibration mode through the same reference electrode (10).Type: GrantFiled: November 5, 2009Date of Patent: May 20, 2014Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite de Franche-ComteInventors: Dorian Gachon, Sylvain Ballandras