Patents Assigned to Universite de Franche-Comte
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Patent number: 8722043Abstract: The present invention relates to the use of anti-human neuropilin-2 antibodies, or of ligands of human neuropilin-2 derived from these antibodies, for obtaining a medicament intended to increase p53 expression and to induce tumor cell apoptosis in the context of an anticancer treatment.Type: GrantFiled: August 26, 2009Date of Patent: May 13, 2014Assignees: Diaclone, EFS Bourgogne Franche Comte, Universite de Franche ComteInventors: Christophe Borg, John Wijdenes, Camille Grandclement
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Patent number: 8472626Abstract: The invention relates to a system (EM, RE) for the optical transmission of a binary code. The invention makes it possible to carry out a coding of the bits transmitted in terms of intensity and phase by choosing a first base in which the signals coding the bits are distinguished only by a first physical quantity, and a second base in which the signals coding the bits are distinguished only by a second physical quantity.Type: GrantFiled: September 24, 2007Date of Patent: June 25, 2013Assignees: Centre National de la Recherche Scientifique—CNRS, Universite de Franche-Comte BesanconInventors: Matthieu Bloch, Jean-Marc Merolla
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Publication number: 20130131466Abstract: A screening tool includes: a compression body for engaging with a portion of a limb of the patient to be compressed; a compression element for compressing the contact surface against the portion of the patient's limb to be compressed; a measurement element for structurally and functionally engaging with a portion of the limb to be examined, as well as generating, via the optical detection of one or more component(s) of the blood, a measurement signal that is characteristic of an arterial pulse in the portion of the limb to be examined during a measurement phase. The compression element generates a measurement pressure substantially equal to a threshold pressure value during the entire measurement phase, and the screening tool also includes: a calculation element for transmitting a negative signal when the arterial pulse is greater than a threshold diagnostic value, and a positive signal it is lower than the threshold value.Type: ApplicationFiled: July 28, 2011Publication date: May 23, 2013Applicants: CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON, UNIVERSITE DE FRANCHE-COMTEInventors: Bruno Wacogne, Christian Pieralli, Stephane Roeslin, Lionel Pazart, Christophe Roncato
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Patent number: 8421559Abstract: The present invention relates to the field of acoustic wave devices, and particularly to that of transducers capable of operating at very high frequencies, from a few hundred MHz to several gigahertz, and its subject is more particularly an interface acoustic wave device including at least two substrates and a layer of ferroelectric material, the latter being contained between a first electrode and a second electrode and having first positive-polarization domains and second negative-polarization domains, the first and second domains being alternated, wherein the assembly constituted by the first electrode, the layer of ferroelectric material, and the second electrode is contained between a first substrate and a second substrate.Type: GrantFiled: September 17, 2009Date of Patent: April 16, 2013Assignees: Etat Francais Represente par le Delegue General pour l'Armement, Centre Nationale de Recherche Scientifique, Université de Franche ComteInventors: Roger Petit, Sylvain Ballandras, Emilie Courjon, Dorian Gachon
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Patent number: 8393224Abstract: The invention relates to a stress gauge of the type having an acoustic resonant structure, including a piezoelectric transducer (10) connected to a holder (20), the holder (20) including opposite the piezoelectric transducer (10) an imbedded reflecting portion (40). The imbedded reflecting portion (40) reflects the volume acoustic waves generated by the piezoelectric transducer (10) when it is excited according to a harmonic mode of the structure and propagating into said holder (20), the reflecting portion (40) being arranged at a distance from the piezoelectric transducer (10) such that the integral of the stress on the propagation distance of the volume acoustic waves up to their reflection is different from zero.Type: GrantFiled: July 18, 2008Date of Patent: March 12, 2013Assignees: Centre National de la Recherche Scientifique, Senseor, Universite de Franche-ComteInventors: Sylvain Jean Ballandras, Jérérmy Masson
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Publication number: 20130060228Abstract: The invention relates to a secure system for the perfusion of a body liquid, enabling a final control of compatability of a treatment with the patient and/or the medical situation previously diagnosed by a doctor, in a simple, efficient and energy-saving manner.Type: ApplicationFiled: October 29, 2010Publication date: March 7, 2013Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ETABLISSEMENT FRANCAIS DU SANG, UNIVERSITE DE FRANCHE-COMTE, CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCONInventors: Lionel Pazart, Bruno François Marcel Wacogne, Christian Gérard Daniel Pieralli, Wilfrid Hervé Boireau, Pascal Charles Serge Morel
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Publication number: 20130027027Abstract: A microtechnique device includes an actuator, designed to move movable equipment with a permanent magnet with respect to a support. The actuator is designed to move the movable equipment in two degrees of freedom from a position of rest, and the permanent magnet is chosen to have a magnetic field distribution that presents a main plane of symmetry and a main direction of magnetization passing through a centre. The device includes a first magnetic sensor and a second magnetic sensor, these two being designed to detect a movement of the magnet. The sensors are positioned with respect to the position of rest of the magnet in a specific manner in the main plane of symmetry of the magnetic field and near to extrema. The first and second sensors are then sensitive to the movements of the movable equipment perpendicular to their respective working axes.Type: ApplicationFiled: January 17, 2011Publication date: January 31, 2013Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, UNIVERSITE DE FRANCHE COMTEInventors: David Heriban, Joel Agnus, Ronan Noizet
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Publication number: 20130030263Abstract: The invention relates to a device (200) for taking a sample of a body fluid, such as blood, to be incorporated into a fluid circuit of a perfusion (100) of a patient who has a perfusion catheter (104), said device having a tubular structure (202) for connecting to the fluid circuit of the perfusion, provided with a zone for intubation, during use, of a sampling channel (300) comprising a distal end (301); and a means (203) for holding, during use, in the tubular structure, the part of the sampling channel (300) comprising a distal end (301) in such a way that the distal end (301) is oriented towards the perfusion catheter (104), in the direction of flow (F1) of the perfusion product (102), from a perfusion product reservoir (101) towards the perfusion catheter (104).Type: ApplicationFiled: October 29, 2010Publication date: January 31, 2013Applicants: Centre National De La Recherche Scientifique, Etablissement Francais Du Sang, Universite de Franche-Comte, Centre Hospitalier Universitaire De BesanconInventors: Lionel Pazart, Bruno François Marcel Wacogne, Christian Gérard Daniel Pieralli, Wilfrid Hervé Boireau, Pascal Charles Serge Morel
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Publication number: 20120267317Abstract: A diffusion insert (1) for a membrane (5), includes a cup (2) defining a donor compartment (20) receiving a donor solution, the base thereof defining an axial port (22) sealed by the membrane (5), a clamping element (3) to pin down the membrane (5), an element for axially locking (4) the clamping element (3), a deformation element (6) capable of deforming the membrane (5) and of protecting the lateral movement directly tangential to the deformation element (6), characterized in that the insert includes a return element (7) for deforming and radially stretching the membrane (5) in a controlled manner. A kit, a cell, a diffusion unit, and a diffusion method for implementing the diffusion insert are also disclosed.Type: ApplicationFiled: October 7, 2010Publication date: October 25, 2012Applicants: CENTRE HOSPITALIER UNIVERSITAIRE, UNIVERSITE DE FRANCHE-COMTEInventors: Youssef Lboutoune, Philippe Humbert, Delphine Binda, Lionel Pazart
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Publication number: 20120206996Abstract: A transponder including a first resonator and a series of one or more second resonators with coupling of evanescent waves exhibiting at least one first resonant mode and one second resonant mode, said first resonator being connected via a first port, to a first means allowing an interrogation, wherein said second resonators are connected via at least one second port, to at least one variable load element capable of modifying coupling conditions of the resonant modes and consequently a response measured on said first port.Type: ApplicationFiled: October 8, 2010Publication date: August 16, 2012Applicants: SENSEOR, UNIVERSITE DE FRANCHE COMTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Sylvain Ballandras, William Daniau, Jean-François Leguen
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Publication number: 20120135520Abstract: The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.Type: ApplicationFiled: July 1, 2010Publication date: May 31, 2012Applicants: CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON, UNIVERSITE DE FRANCHE-COMTEInventors: Philippe Humbert, Delphine Binda, Celine Viennet-Steiner, Sophie Robin, Helene Tauzin, Gwenael Rolin, Lionel Pazart
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Publication number: 20120116722Abstract: A method for detecting defects in an electrochemical device, including obtaining at least one characteristic value dependent on at least one variable received from the electrochemical device and determining at least one defect in said device from the characteristic value obtained. The method comprises a mathematical operation including a wavelet transform, which operation is carried out in order to obtain the characteristic value from the variable received. The invention also relates to a device that carries out one such method, as well as to a corresponding computer program.Type: ApplicationFiled: June 24, 2010Publication date: May 10, 2012Applicants: ELECTRICITE DE FRANCE, UNIVERSITE DE FRANCHE-COMTE, INRETSInventors: Nadia Yousfi-Steiner, Philippe Mocoteguy, Ludmila Gautier, Daniel Hissel, Denis Candusso
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Patent number: 8138856Abstract: An acoustic wave device comprising a piezoelectric layer on an omnidirectional acoustic mirror and excitation and/or reception means on a surface of said piezoelectric layer, capable of exciting waves in a band gap of the acoustic mirror.Type: GrantFiled: January 28, 2011Date of Patent: March 20, 2012Assignees: Centre National de la Recherche Scientifique, Universite de Franche ComteInventors: Abdelkrim Khelif, Abdelkrim Choujaa, Vincent Laude
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Publication number: 20110260811Abstract: The elementary filter of the HBAR type includes two resonators (20, 22) of the HBAR type which are each formed by a transducer (8) and a substrate (12) which are coupled in a suitable manner by electroacoustic waves. The first resonator (20), the second resonator (22) and the coupling element (28) by way of evanescent waves include the same monobloc acoustic substrate (12) which is arranged facing and coupled to the piezoelectric transducer (8) by waves having the same longitudinal or transverse vibration mode through the same reference electrode (10).Type: ApplicationFiled: November 5, 2009Publication date: October 27, 2011Applicants: Centre Natianl De La Recherche Scientifique (C.N.R.S), UNIVERSITE DE FRANCHE COMTEInventors: Dorian Gachon, Sylvain Ballandras
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Publication number: 20110133859Abstract: An acoustic wave device comprising a piezoelectric layer on an omnidirectional acoustic mirror and excitation and/or reception means on a surface of said piezoelectric layer, capable of exciting waves in a band gap of the acoustic mirror.Type: ApplicationFiled: January 28, 2011Publication date: June 9, 2011Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE COMTEInventors: Abdelkrim KHELIF, Abdelkrim CHOUJAA, Vincent LAUDE
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Publication number: 20110133857Abstract: The present invention relates to the field of acoustic wave devices, and particularly to that of transducers capable of operating at very high frequencies, from a few hundred MHz to several gigahertz, and its subject is more particularly an interface acoustic wave device including at least two substrates and a layer of ferroelectric material, the latter being contained between a first electrode and a second electrode and having first positive-polarization domains and second negative-polarization domains, the first and second domains being alternated, wherein the assembly constituted by the first electrode, the layer of ferroelectric material, and the second electrode is contained between a first substrate and a second substrate.Type: ApplicationFiled: September 17, 2009Publication date: June 9, 2011Applicants: ETAT FRANCAIS REPRESENTE PAR LE DELEGUE GENERAL POUR L'ARMEMENT, CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE FRANCHE COMTEInventors: Roger Petit, Sylvain Ballandras, Emilie Courjon, Dorian Gachon
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Patent number: 7880563Abstract: An acoustic wave device comprising a piezoelectric layer on an omnidirectional acoustic mirror and excitation and/or reception means on a surface of said piezoelectric layer, capable of exciting waves in a band gap of the acoustic mirror.Type: GrantFiled: February 16, 2006Date of Patent: February 1, 2011Assignees: Centre National de la Recherche Scientifique, Universite de Franche ComteInventors: Abdelkrim Khelif, Abdelkrim Choujaa, Vincent Laude
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Publication number: 20100119896Abstract: A process for the production of dihydrogen from hydrogenated silicon by bringing the hydrogenated silicon into contact with an alkaline solution. Devices of the fuel cell type using this hydrogen production method are also described.Type: ApplicationFiled: May 2, 2008Publication date: May 13, 2010Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.), UNIVERSITE DE FRANCHE-COMTEInventor: Bernard Gauthier-Manuel
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Publication number: 20100111304Abstract: The invention relates to a system (EM, RE) for the optical transmission of a binary code. The invention makes it possible to carry out a coding of the hits transmitted in terms of intensity and phase by choosing a first base in which the signals coding the hits are distinguished only by a first physical quantity, and a second base in which the signals coding the hits are distinguished only by a second physical quantity.Type: ApplicationFiled: September 24, 2007Publication date: May 6, 2010Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITE DE FRANCHE-COMTE BESANCONInventors: Matthieu Bloch, Jean-Marc Merolla
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Publication number: 20090310965Abstract: The invention concerns a device (100) for receiving an optical signal comprising at least one optical signal of angular frequency ?0 modulated by an electrical signal of angular frequency ? whose phase ?1 varies according to the value of at least data bit to be transmitted. The reception device (100) comprises a polarisation separator (105) for separating the modulated optical signal of angular frequency ?0, into first and second optical signals of different polarisation, means (140, 102, 103, 104) of obtaining two electrical signals, means (110a) of modulating the first optical signal from the first electrical signal, means (110b) of modulating the second optical signal from the second electrical signal, and means (115) of combining the first modulated optical signal and the second modulated optical signal in order to form a recombined optical signal.Type: ApplicationFiled: July 13, 2006Publication date: December 17, 2009Applicants: SMARTQUANTUM SA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE-COMTEInventors: Jean-Marc Merolla, Johann Cussey, Frédéric Patois, Nicolas Pelloquin