Patents Assigned to UNIVERSITE GRENOBLE ALPES
  • Patent number: 11104578
    Abstract: The invention relates to an exfoliation method according to which a fluid loaded with particles flows at a first flow rate into a first (2), and then into a second, section of a pipe (1), the first flow rate being suitable for generating shear stresses and cavitation bubbles in the fluid as it passes through the first section (2) of the pipe (1), the second section (3) having a hydraulic diameter suitable for bringing about an implosion of cavitation bubbles as soon as the fluid exits the first section (2) and flows into the second section (3), so that an exfoliation of the particles is brought about under the combined action of the shear stresses and a shock wave generated by the implosion of the cavitation bubbles, the first section (2) having a hydraulic diameter less than 300 ?m.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: August 31, 2021
    Assignee: UNIVERSITE GRENOBLE ALPES
    Inventors: Frédéric Ayela, Damien Colombet
  • Patent number: 11097336
    Abstract: A device and method for producing metal slugs, in which: a movable support has a plurality of cavities separated by partition walls, such that the cavities travel over a path, a feeding means is positioned above a location on said path and is capable of forming a stream of molten metal, flowing under the effect of gravity, such that, during the continuous movement of the movable support, the continuous stream of molten metal from the feeding means is divided or fragmented into slugs formed successively in said cavities, under the effect of said partition walls.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: August 24, 2021
    Assignees: UNIVERSITE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLE
    Inventors: Sébastien Gravier, Georges Kapelski
  • Publication number: 20210253760
    Abstract: The present invention relates to a comb polymer comprising a main chain formed from 1-ethenyl- and/or 1-allyl-2,3,4,5,6-pentafluorobenzene monomers and polymeric side chains grafted in the para position of the pentafluorophenyl groups, in which said polymeric side chains are linked to said main chain by an oxygen atom, the molar grafting rate of polymeric side chains being greater than or equal to 50%. It also relates to a method for the preparation of such a comb polymer.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 19, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Lionel PICARD, Thomas CLEMENT, Patrice RANNOU
  • Publication number: 20210245613
    Abstract: An electrical power converter unit (2) includes: a first connection interface (10) comprising two leads (12, 14) forming a DC input/output interface for connecting a first electrical device to the power converter unit, a three-phase rectifier power converter circuit (16) and a second connection interface (30) for connecting a second electrical device to the power converter unit. The second connection interface includes a switching unit (46) adapted to switch between:—a DC input/output mode, in which first, second and third arms of the power converter circuit (16) are electrically connected together, forming one DC input/output; and—an AC input/output mode, in which the arms are disconnected from each other, forming separate input/outputs for a three-phase AC voltage.
    Type: Application
    Filed: July 25, 2018
    Publication date: August 12, 2021
    Applicants: VOLVO TRUCK CORPORATION, UNIVERSITE GRENOBLE ALPES
    Inventors: Michael MILLET, Christophe MAGNET, David FREY, Julien RICHER, Philippe LE BRUSQ
  • Publication number: 20210219955
    Abstract: The invention relates to a sheath (10) for an endoscopic ultrasound probe, comprising: a first flexible portion (10a) suited to surrounding a catheter (4) of the ultrasound probe, made of a material suited to allowing ultrasounds to pass, having a closed distal end, a second portion (10b) suited to surrounding a handle (2) and a cable (3) for electrically connecting the probe to an ultrasound station, and a fitting (11) arranged between the first and the second portion (10a, 10b), said fitting (11) being suited to being removably attached to the handle (2).
    Type: Application
    Filed: June 3, 2019
    Publication date: July 22, 2021
    Applicant: Universite Grenoble Alpes
    Inventors: Guillaume Custillon, Nicolas Dubois
  • Publication number: 20210212570
    Abstract: The invention relates to a photoacoustic ultrasound probe (100), comprising: a catheter (4), an ultrasound sensor (5) arranged at a distal end (40) of the catheter, at least one optical fibre (50) suited to being connected to a laser source, said optical fibre extending into the catheter up to the distal end (40), said probe being characterised in that the catheter has an inclined distal portion (42) and/or a bevelled distal end (40).
    Type: Application
    Filed: June 3, 2019
    Publication date: July 15, 2021
    Applicant: Universite Grenoble Alpes
    Inventors: Guillaume Custillon, Nicolas Dubois
  • Patent number: 11061325
    Abstract: A photosensitive composition activatable by multiphoton absorption usable for the fabrication of a three-dimensional structure which is biodegradable and/or biocompatible and/or bioresorbable. This structure is usable as a matrix for cell culture. The photosensitive composition comprises: gelatin, collagen, a water-soluble photoinitiator, able to be excited by several photons and capable of generating singlet oxygen, optionally a cell adhesion promoter, and water. A process for preparing the photosensitive composition, a process for preparing a three-dimensional structure from the photosensitive composition, the three-dimensional structure obtained by this preparation process and a matrix for cell culture comprising this structure.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 13, 2021
    Assignee: UNIVERSITE GRENOBLE ALPES
    Inventors: Olivier Stephan, Laetitia Gredy
  • Publication number: 20210196172
    Abstract: A method for determining a membership function, the membership functions allowing a stress level of a user to be determined on the basis of a physiological parameter measured on the user, the membership function varying, depending on the physiological parameter, between: a first value, representative of a rest state; and a second value, representative of a stressed state; the membership function taking into account a distribution function, which is defined beforehand, the distribution function being a continuous and monotonic function, the distribution function being applied to a normalized parameter established on the basis of a measured physiological parameter, the method comprising determining a normalization function, and optionally a standardization function, the normalization function and the optional standardization function being determined on the basis of physiological parameters measured on a plurality of test individuals, in various calibration periods.
    Type: Application
    Filed: December 23, 2020
    Publication date: July 1, 2021
    Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, UNIVERSITE GRENOBLE ALPES
    Inventors: Gaël VILA, Christelle GODIN
  • Patent number: 11045539
    Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: June 29, 2021
    Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes, Establissement Francais Du Sang
    Inventors: Audrey Le Gouellec, Bertrand Toussaint, Jean-Luc Lenormand, David Laurin, Elodie Meynet
  • Patent number: 11040191
    Abstract: The invention concerns a method of forming a medical device, the method comprising: forming a graphene film (100) over a substrate (204); depositing, by gas phase deposition, a polymer material covering a surface of the graphene film (100); and removing the substrate (204) from the graphene film (100), wherein the polymer material forms a support (102) for the graphene film (100).
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: June 22, 2021
    Assignees: Centre National de la Recherche Scientifique, UNIVERSITE GRENOBLE ALPES
    Inventors: Dipankar Kalita, Vincent Bouchiat, Laetitia Marty, Nedjma Bendiab
  • Publication number: 20210147899
    Abstract: Method for determining the sensitivity of a bacterial strain of interest to a viral strain of bacteriophages, the method comprising: a) preparing a sample, this comprising bringing bacteria, belonging to the bacterial strain of interest, into contact with bacteriophages, each bacteriophage belonging to the same viral strain, the bacteria being either in a liquid medium, or in an agar medium; b) placing the sample between a light source and an image sensor, the light source emitting a light wave in an emission spectral band comprised between 500 nm and 600 nm; c) illuminating the sample using the light source and acquiring at least one image of the sample, with the image sensor, in the emission spectral band, no image-forming optic being placed between the sample and the image sensor; d) on the basis of the acquired images, determining a sensitivity of the bacterial strain of interest to the viral strain.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 20, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES
    Inventors: Prisca PERLEMOINE, Thomas BORDY, Pierre MARCOUX, Emmanuel PICARD, Rémi TOUTAIN, Marc ZELSMANN, Alexis MAIRE
  • Patent number: 11005261
    Abstract: A control method allows the control of an installation for transmitting electricity comprising a DC transmission network including a group of electricity transmission lines that are linked to one another. The method allows the opening of at least one N-1 safety system, for each safety system being opened, the contribution to the flow of current through the group of transmission lines, originating from the converter station associated with the safety system that is opened, is removed. Furthermore, the method also allows a search for the short-circuit fault in order to identify the faulty transmission line, and an operation, implemented after identification of the faulty transmission line by the search step, of isolating the faulty transmission line by opening the line circuit breakers of the faulty transmission line.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: May 11, 2021
    Assignees: Supergrid Institute, Universite Grenoble Alpes
    Inventors: Dieynaba Loume, Alberto Bertinato, Bertrand Raison
  • Publication number: 20210130385
    Abstract: The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.
    Type: Application
    Filed: December 27, 2017
    Publication date: May 6, 2021
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITE GRENOBLE ALPES
    Inventors: Pierre FALSON, Julien DAUVERGNE, Ahcène BOUMENDJEL, Marine PEUCHMAUR, Kim Anh NGUYEN, Sandrine MAGNARD
  • Patent number: 10978234
    Abstract: A magnetic stack includes a first element including a ferromagnetic layer; a second element including a metal layer able to confer on the assembly formed by the first and the second elements a magnetic anisotropy perpendicular to the plane of the layers. The first element further includes a refractory metal material, the second element being arranged on the first element.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: April 13, 2021
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITÉ GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Jyotirmoy Chatterjee, Paulo Veloso Coelho, Bernard Dieny, Ricardo Sousa, Lucian Prejbeanu
  • Patent number: 10960191
    Abstract: The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: March 30, 2021
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE
    Inventors: Philippe Cinquin, Dominique Schneider, Max Maurin, Donald Martin, Sarra El Ichi, Abdelkader Zebda, Jean-Pierre Alcaraz, Fabian Reche, Patrick Tuvignon, Jacques Thelu, Audrey Le Gouellec, Bertrand Toussaint
  • Patent number: 10951034
    Abstract: A method of protecting a high-voltage network comprising the steps for maintaining first controlled switches closed and second controlled switches open; measuring voltage and current on high-voltage interfaces; communicating the direction of the current to the other end of a high-voltage line; for each node: identifying a fault; verifying that the current is lower than the current interruption capability of the high-voltage interface switch and opening this switch.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: March 16, 2021
    Assignees: Supergrid Institute, Institut Polytechnique De Grenoble, Universite Grenoble Alpes
    Inventors: William Leon Garcia, Alberto Bertinato, Bertrand Raison, Pascal Tixador, Bruno Luscan
  • Patent number: 10935546
    Abstract: The present invention deals with heterotrimeric AMP-activated protein kinase (AMPK) comprising a fluorophore pair wherein the conformational change can be measured by FRET. It represents an advanced tool to screen and identify AMPK interactors in vitro and in cells in vivo. Such invention can also be considered as a reporter of the cellular energy status as it allows the spatiotemporal monitoring, in situ, of fluctuations in the ratio of AMP and ADP versus ATP.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: March 2, 2021
    Assignees: Universite Grenoble Alpes, European Molecular Biology Laboratory
    Inventors: Imre Berger, Martin Pelosse, Uwe Schlattner
  • Patent number: 10928369
    Abstract: The invention relates to a method for calibrating an electronic nose, said electronic nose comprising a plurality of optical sensors arranged on a surface and capable of being in contact with a gaseous medium of interest, said optical sensors being capable of delivering a signal representative of the local optical index of the gaseous medium of interest when they are excited by photons, the method being characterized in that it comprises the following steps: after having placed the electronic nose in a gaseous medium of interest at the initial pressure (P0) and the initial temperature (T0): a) sending photons in the direction of the sensors so as to excite said sensors; b) measuring the signal delivered by each of the sensors, this measurement providing as many responses as there are sensors; c) modifying the pressure and/or temperature of the gaseous medium of interest; d) repeating step b); and e) for each sensor, determining a correction factor such as a variation in the signal between steps d) and b) corr
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: February 23, 2021
    Assignees: ARYBALLE TECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT A L'ENERGIE ATOMIQUE, UNIVERSITE GRENOBLE ALPES
    Inventors: Cyril Herrier, Yanxia Hou-Broutin, Francois-Xavier Gallat, Thierry Livache, Tristan Rousselle
  • Patent number: 10918647
    Abstract: The invention provides antifungal compounds, antifungal compositions, and intermediates for the preparation of antifungal compounds and antifungal compositions. The invention also provides methods of inhibiting fungi and methods of treating fungal infections, for example, with a compound or composition described herein. The antifungal compositions can include antifungal adjuvants such as essential oils or essential oil extracts, which adjuvants further improve the antifungal activity of the compositions.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: February 16, 2021
    Assignees: University of Southern California, CNRS, Universite Grenoble Alpes, INSERM
    Inventors: Charles E. McKenna, Carlo Petosa, Jerome Govin, Boris A. Kashemirov, Elena Ferri, Flore Mietton
  • Publication number: 20210013040
    Abstract: A method for forming spacers on a gate pattern includes deposition of a first dielectric layer having basal portions on an active layer and side portions of the edges of the pattern; anisotropic modification of only the basal portions of the first layer, so as to obtain modified basal portions; deposition of a second dielectric layer on the first layer, also having basal and side portions; anisotropic etching of only the basal portions of the second layer, so as to remove these basal portions while conserving the side portions; and removal of the modified basal portions while conserving the first and second non-modified side portions, by selective etching of the modified dielectric material vis-à-vis the non-modified dielectric material.
    Type: Application
    Filed: July 10, 2020
    Publication date: January 14, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE GRENOBLE ALPES
    Inventors: Nicolas POSSEME, Marceline BONVALOT, Ahmad CHAKER, Christophe VALLEE