Patents Assigned to UNIVERSITE GRENOBLE ALPES
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Patent number: 11104578Abstract: The invention relates to an exfoliation method according to which a fluid loaded with particles flows at a first flow rate into a first (2), and then into a second, section of a pipe (1), the first flow rate being suitable for generating shear stresses and cavitation bubbles in the fluid as it passes through the first section (2) of the pipe (1), the second section (3) having a hydraulic diameter suitable for bringing about an implosion of cavitation bubbles as soon as the fluid exits the first section (2) and flows into the second section (3), so that an exfoliation of the particles is brought about under the combined action of the shear stresses and a shock wave generated by the implosion of the cavitation bubbles, the first section (2) having a hydraulic diameter less than 300 ?m.Type: GrantFiled: May 16, 2017Date of Patent: August 31, 2021Assignee: UNIVERSITE GRENOBLE ALPESInventors: Frédéric Ayela, Damien Colombet
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Patent number: 11097336Abstract: A device and method for producing metal slugs, in which: a movable support has a plurality of cavities separated by partition walls, such that the cavities travel over a path, a feeding means is positioned above a location on said path and is capable of forming a stream of molten metal, flowing under the effect of gravity, such that, during the continuous movement of the movable support, the continuous stream of molten metal from the feeding means is divided or fragmented into slugs formed successively in said cavities, under the effect of said partition walls.Type: GrantFiled: July 9, 2018Date of Patent: August 24, 2021Assignees: UNIVERSITE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLEInventors: Sébastien Gravier, Georges Kapelski
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Publication number: 20210253760Abstract: The present invention relates to a comb polymer comprising a main chain formed from 1-ethenyl- and/or 1-allyl-2,3,4,5,6-pentafluorobenzene monomers and polymeric side chains grafted in the para position of the pentafluorophenyl groups, in which said polymeric side chains are linked to said main chain by an oxygen atom, the molar grafting rate of polymeric side chains being greater than or equal to 50%. It also relates to a method for the preparation of such a comb polymer.Type: ApplicationFiled: February 12, 2021Publication date: August 19, 2021Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Lionel PICARD, Thomas CLEMENT, Patrice RANNOU
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Publication number: 20210245613Abstract: An electrical power converter unit (2) includes: a first connection interface (10) comprising two leads (12, 14) forming a DC input/output interface for connecting a first electrical device to the power converter unit, a three-phase rectifier power converter circuit (16) and a second connection interface (30) for connecting a second electrical device to the power converter unit. The second connection interface includes a switching unit (46) adapted to switch between:—a DC input/output mode, in which first, second and third arms of the power converter circuit (16) are electrically connected together, forming one DC input/output; and—an AC input/output mode, in which the arms are disconnected from each other, forming separate input/outputs for a three-phase AC voltage.Type: ApplicationFiled: July 25, 2018Publication date: August 12, 2021Applicants: VOLVO TRUCK CORPORATION, UNIVERSITE GRENOBLE ALPESInventors: Michael MILLET, Christophe MAGNET, David FREY, Julien RICHER, Philippe LE BRUSQ
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Publication number: 20210219955Abstract: The invention relates to a sheath (10) for an endoscopic ultrasound probe, comprising: a first flexible portion (10a) suited to surrounding a catheter (4) of the ultrasound probe, made of a material suited to allowing ultrasounds to pass, having a closed distal end, a second portion (10b) suited to surrounding a handle (2) and a cable (3) for electrically connecting the probe to an ultrasound station, and a fitting (11) arranged between the first and the second portion (10a, 10b), said fitting (11) being suited to being removably attached to the handle (2).Type: ApplicationFiled: June 3, 2019Publication date: July 22, 2021Applicant: Universite Grenoble AlpesInventors: Guillaume Custillon, Nicolas Dubois
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Publication number: 20210212570Abstract: The invention relates to a photoacoustic ultrasound probe (100), comprising: a catheter (4), an ultrasound sensor (5) arranged at a distal end (40) of the catheter, at least one optical fibre (50) suited to being connected to a laser source, said optical fibre extending into the catheter up to the distal end (40), said probe being characterised in that the catheter has an inclined distal portion (42) and/or a bevelled distal end (40).Type: ApplicationFiled: June 3, 2019Publication date: July 15, 2021Applicant: Universite Grenoble AlpesInventors: Guillaume Custillon, Nicolas Dubois
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Patent number: 11061325Abstract: A photosensitive composition activatable by multiphoton absorption usable for the fabrication of a three-dimensional structure which is biodegradable and/or biocompatible and/or bioresorbable. This structure is usable as a matrix for cell culture. The photosensitive composition comprises: gelatin, collagen, a water-soluble photoinitiator, able to be excited by several photons and capable of generating singlet oxygen, optionally a cell adhesion promoter, and water. A process for preparing the photosensitive composition, a process for preparing a three-dimensional structure from the photosensitive composition, the three-dimensional structure obtained by this preparation process and a matrix for cell culture comprising this structure.Type: GrantFiled: March 29, 2017Date of Patent: July 13, 2021Assignee: UNIVERSITE GRENOBLE ALPESInventors: Olivier Stephan, Laetitia Gredy
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Publication number: 20210196172Abstract: A method for determining a membership function, the membership functions allowing a stress level of a user to be determined on the basis of a physiological parameter measured on the user, the membership function varying, depending on the physiological parameter, between: a first value, representative of a rest state; and a second value, representative of a stressed state; the membership function taking into account a distribution function, which is defined beforehand, the distribution function being a continuous and monotonic function, the distribution function being applied to a normalized parameter established on the basis of a measured physiological parameter, the method comprising determining a normalization function, and optionally a standardization function, the normalization function and the optional standardization function being determined on the basis of physiological parameters measured on a plurality of test individuals, in various calibration periods.Type: ApplicationFiled: December 23, 2020Publication date: July 1, 2021Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, UNIVERSITE GRENOBLE ALPESInventors: Gaël VILA, Christelle GODIN
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Patent number: 11045539Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.Type: GrantFiled: February 15, 2018Date of Patent: June 29, 2021Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes, Establissement Francais Du SangInventors: Audrey Le Gouellec, Bertrand Toussaint, Jean-Luc Lenormand, David Laurin, Elodie Meynet
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Patent number: 11040191Abstract: The invention concerns a method of forming a medical device, the method comprising: forming a graphene film (100) over a substrate (204); depositing, by gas phase deposition, a polymer material covering a surface of the graphene film (100); and removing the substrate (204) from the graphene film (100), wherein the polymer material forms a support (102) for the graphene film (100).Type: GrantFiled: March 9, 2016Date of Patent: June 22, 2021Assignees: Centre National de la Recherche Scientifique, UNIVERSITE GRENOBLE ALPESInventors: Dipankar Kalita, Vincent Bouchiat, Laetitia Marty, Nedjma Bendiab
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Publication number: 20210147899Abstract: Method for determining the sensitivity of a bacterial strain of interest to a viral strain of bacteriophages, the method comprising: a) preparing a sample, this comprising bringing bacteria, belonging to the bacterial strain of interest, into contact with bacteriophages, each bacteriophage belonging to the same viral strain, the bacteria being either in a liquid medium, or in an agar medium; b) placing the sample between a light source and an image sensor, the light source emitting a light wave in an emission spectral band comprised between 500 nm and 600 nm; c) illuminating the sample using the light source and acquiring at least one image of the sample, with the image sensor, in the emission spectral band, no image-forming optic being placed between the sample and the image sensor; d) on the basis of the acquired images, determining a sensitivity of the bacterial strain of interest to the viral strain.Type: ApplicationFiled: November 13, 2020Publication date: May 20, 2021Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPESInventors: Prisca PERLEMOINE, Thomas BORDY, Pierre MARCOUX, Emmanuel PICARD, Rémi TOUTAIN, Marc ZELSMANN, Alexis MAIRE
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Patent number: 11005261Abstract: A control method allows the control of an installation for transmitting electricity comprising a DC transmission network including a group of electricity transmission lines that are linked to one another. The method allows the opening of at least one N-1 safety system, for each safety system being opened, the contribution to the flow of current through the group of transmission lines, originating from the converter station associated with the safety system that is opened, is removed. Furthermore, the method also allows a search for the short-circuit fault in order to identify the faulty transmission line, and an operation, implemented after identification of the faulty transmission line by the search step, of isolating the faulty transmission line by opening the line circuit breakers of the faulty transmission line.Type: GrantFiled: August 30, 2017Date of Patent: May 11, 2021Assignees: Supergrid Institute, Universite Grenoble AlpesInventors: Dieynaba Loume, Alberto Bertinato, Bertrand Raison
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Publication number: 20210130385Abstract: The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.Type: ApplicationFiled: December 27, 2017Publication date: May 6, 2021Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITE GRENOBLE ALPESInventors: Pierre FALSON, Julien DAUVERGNE, Ahcène BOUMENDJEL, Marine PEUCHMAUR, Kim Anh NGUYEN, Sandrine MAGNARD
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Patent number: 10978234Abstract: A magnetic stack includes a first element including a ferromagnetic layer; a second element including a metal layer able to confer on the assembly formed by the first and the second elements a magnetic anisotropy perpendicular to the plane of the layers. The first element further includes a refractory metal material, the second element being arranged on the first element.Type: GrantFiled: February 15, 2019Date of Patent: April 13, 2021Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITÉ GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Jyotirmoy Chatterjee, Paulo Veloso Coelho, Bernard Dieny, Ricardo Sousa, Lucian Prejbeanu
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Patent number: 10960191Abstract: The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.Type: GrantFiled: April 4, 2016Date of Patent: March 30, 2021Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLEInventors: Philippe Cinquin, Dominique Schneider, Max Maurin, Donald Martin, Sarra El Ichi, Abdelkader Zebda, Jean-Pierre Alcaraz, Fabian Reche, Patrick Tuvignon, Jacques Thelu, Audrey Le Gouellec, Bertrand Toussaint
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Patent number: 10951034Abstract: A method of protecting a high-voltage network comprising the steps for maintaining first controlled switches closed and second controlled switches open; measuring voltage and current on high-voltage interfaces; communicating the direction of the current to the other end of a high-voltage line; for each node: identifying a fault; verifying that the current is lower than the current interruption capability of the high-voltage interface switch and opening this switch.Type: GrantFiled: September 11, 2017Date of Patent: March 16, 2021Assignees: Supergrid Institute, Institut Polytechnique De Grenoble, Universite Grenoble AlpesInventors: William Leon Garcia, Alberto Bertinato, Bertrand Raison, Pascal Tixador, Bruno Luscan
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Patent number: 10935546Abstract: The present invention deals with heterotrimeric AMP-activated protein kinase (AMPK) comprising a fluorophore pair wherein the conformational change can be measured by FRET. It represents an advanced tool to screen and identify AMPK interactors in vitro and in cells in vivo. Such invention can also be considered as a reporter of the cellular energy status as it allows the spatiotemporal monitoring, in situ, of fluctuations in the ratio of AMP and ADP versus ATP.Type: GrantFiled: June 18, 2015Date of Patent: March 2, 2021Assignees: Universite Grenoble Alpes, European Molecular Biology LaboratoryInventors: Imre Berger, Martin Pelosse, Uwe Schlattner
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Patent number: 10928369Abstract: The invention relates to a method for calibrating an electronic nose, said electronic nose comprising a plurality of optical sensors arranged on a surface and capable of being in contact with a gaseous medium of interest, said optical sensors being capable of delivering a signal representative of the local optical index of the gaseous medium of interest when they are excited by photons, the method being characterized in that it comprises the following steps: after having placed the electronic nose in a gaseous medium of interest at the initial pressure (P0) and the initial temperature (T0): a) sending photons in the direction of the sensors so as to excite said sensors; b) measuring the signal delivered by each of the sensors, this measurement providing as many responses as there are sensors; c) modifying the pressure and/or temperature of the gaseous medium of interest; d) repeating step b); and e) for each sensor, determining a correction factor such as a variation in the signal between steps d) and b) corrType: GrantFiled: March 2, 2018Date of Patent: February 23, 2021Assignees: ARYBALLE TECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT A L'ENERGIE ATOMIQUE, UNIVERSITE GRENOBLE ALPESInventors: Cyril Herrier, Yanxia Hou-Broutin, Francois-Xavier Gallat, Thierry Livache, Tristan Rousselle
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Patent number: 10918647Abstract: The invention provides antifungal compounds, antifungal compositions, and intermediates for the preparation of antifungal compounds and antifungal compositions. The invention also provides methods of inhibiting fungi and methods of treating fungal infections, for example, with a compound or composition described herein. The antifungal compositions can include antifungal adjuvants such as essential oils or essential oil extracts, which adjuvants further improve the antifungal activity of the compositions.Type: GrantFiled: July 26, 2017Date of Patent: February 16, 2021Assignees: University of Southern California, CNRS, Universite Grenoble Alpes, INSERMInventors: Charles E. McKenna, Carlo Petosa, Jerome Govin, Boris A. Kashemirov, Elena Ferri, Flore Mietton
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Publication number: 20210013040Abstract: A method for forming spacers on a gate pattern includes deposition of a first dielectric layer having basal portions on an active layer and side portions of the edges of the pattern; anisotropic modification of only the basal portions of the first layer, so as to obtain modified basal portions; deposition of a second dielectric layer on the first layer, also having basal and side portions; anisotropic etching of only the basal portions of the second layer, so as to remove these basal portions while conserving the side portions; and removal of the modified basal portions while conserving the first and second non-modified side portions, by selective etching of the modified dielectric material vis-à-vis the non-modified dielectric material.Type: ApplicationFiled: July 10, 2020Publication date: January 14, 2021Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE GRENOBLE ALPESInventors: Nicolas POSSEME, Marceline BONVALOT, Ahmad CHAKER, Christophe VALLEE