Patents Assigned to UNIVERSITE GRENOBLE ALPES
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Patent number: 10106858Abstract: Disclosed is a method for the in vitro detection of strains of Legionella pneumophila, resistant to antibiotics, in particular to the fluoroquinolones. Also disclosed are nucleotide probes and a kit of reagents allowing the detection of Legionella pneumophila bacterial strains that are resistant to antibiotics, in particular of the fluoroquinolone type.Type: GrantFiled: June 17, 2014Date of Patent: October 23, 2018Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Max Maurice Louis Maurin, Dominique Schneider, Lubana Shadoud, Sophie Jarraud, Jean Francois Timsit, Jerome Etienne
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Patent number: 10093988Abstract: The invention relates to oligonucleotides and to the use thereof as universal primers for the detection and identification of amphibia/fish species, especially in complex and deteriorated substrates. The invention also relates to a method for detecting and identifying amphibia/fish species in samples collected from the environment (ground, water, faeces) or from industry (especially transformed products). The invention further relates to a kit for said detection.Type: GrantFiled: May 25, 2012Date of Patent: October 9, 2018Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Pierre Taberlet, Eric Coissac, Tiayyba Riaz
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Publication number: 20180279887Abstract: A device non-invasively measures aortic flow in the subdiaphragmatic region in a small laboratory mammal. The device includes a device for plethysmography of the thorax by inductance measurement, having two electrically conducting, extendible coils rigidly attached to an elastic garment that is adjustable to the torso of the mammal, a device for acquiring the signal from variation in the cross-section of each coil, and a processor configured to calculate the instantaneous subdiaphragmatic aortic flow of the mammal from the signals from the variation in cross-section of each coil and from a functional model of the cardiorespiratory system. The exchanges of blood between the thorax and the rest of the body of the mammal include an output of blood via the abdominal aorta in the subdiaphragmatic region and an input of blood via the inferior vena cava.Type: ApplicationFiled: August 26, 2016Publication date: October 4, 2018Applicant: UNIVERSITE GRENOBLE ALPESInventors: Pierre BACONNIER, François BOUCHER, Pierre-Yves GUMERY
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Publication number: 20180287166Abstract: An electrochemical reactor block including at least two pellets cut out of a flexible conductive film including chains of a linear polymer, carbon nanotubes being bound to each of the chains by pi-pi interaction, a catalyst agent selected from the group including enzymes, metal catalysts, macrocyclic catalysts, and redox mediators being trapped between the pellets.Type: ApplicationFiled: September 14, 2016Publication date: October 4, 2018Applicant: Universite Grenoble-AlpesInventors: Serge Cosnier, Raoudha Haddad
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Patent number: 10056266Abstract: A method for manufacturing a resistive device, includes depositing a first electrically conductive layer on a substrate; forming an etching mask on the first conductive layer; etching the first conductive layer through the mask, such as to obtain a plurality of electrically conductive pillars separated from one another; and forming storage elements with variable electrical resistance at the tops of the electrically conductive pillars, such that each storage element is supported by one of the electrically conductive pillars, the step of forming the storage elements including the following operations depositing a first layer by non-collimated cathode sputtering at normal incidence relative to the substrate; and depositing a second layer on the first layer by cathode sputtering, the second layer including a first chemical species sputtered at an oblique incidence.Type: GrantFiled: October 15, 2015Date of Patent: August 21, 2018Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE GRENOBLE ALPESInventors: Bernard Dieny, Maxime Darnon, Gabriele Navarro, Olivier Joubert
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Patent number: 10039568Abstract: The invention relates to a device for guiding a medical needle, including said medical needle (1) and an insert (2) that is rotatably, translatably, and slidably arranged in the needle (1), wherein said device is characterized in that the insert (2) has, in the free state thereof, a curved distal portion (21), and in that the needle has at least two regions (11, 12), the mechanical behaviors of which are different, wherein the mechanical behaviors of each region (11, 12) and of the curved distal portion (21) of the insert are selected such that a movement of the insert (2) into the needle (1) causes a local deformation of the needle and/or of the insert. The invention also relates to a method for manufacturing said device.Type: GrantFiled: October 18, 2012Date of Patent: August 7, 2018Assignee: UNIVERSITE GRENOBLE ALPESInventors: Denis Favier, Thierry Alonso, Gregory Chagnon, Yinong Liu, Alexandre Moreau-Gaudry
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Publication number: 20180211829Abstract: The invention relates to a method for manufacturing an optoelectronic device (50) including wire-like, conical, or frustoconical semiconductor elements (20) predominantly comprising a III-V compound. Each semiconductor element extends along an axis and includes a portion (54), the side surfaces (55) of which are covered with a shell (56) including at least one active region (31), wherein the portions are created by continuous growth in a reactor, and wherein the temperature in the reactor varies in an uninterrupted manner from a first temperature value that favors growth of first crystallographic planes perpendicular to said axis, to a second temperature value that is strictly lower than the first temperature value and favors growth of second crystallographic planes parallel to said axis.Type: ApplicationFiled: July 13, 2016Publication date: July 26, 2018Applicants: Aledia, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Universite Grenoble AlpesInventors: Philipe Gilet, Amélie Dussaigne, Damien Salomon, Joel Eymery, Christophe Durand
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Patent number: 10007983Abstract: The present disclosure relates to an image processing method including the following steps: receiving a deformation or displacement image; defining a meshing of the deformation image; assigning a respective pair of unknown variables to each node of the meshing; detecting one (or more) node(s) located at the boundary between two different materials of the body studied; enriching the node(s) detected; calculating a basic matrix for each basic cell of the meshing; assembling the basic matrixes in order to obtain an overall structural matrix; calculating a resilience image of the body based on the overall structural matrix.Type: GrantFiled: September 3, 2014Date of Patent: June 26, 2018Assignee: Universite Grenoble AlpesInventors: Jacques Ohayon, Adeline Bouvier, Guy Cloutier
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Publication number: 20180159241Abstract: The invention relates to a glazing including a glass sheet, one surface of which is covered with a conductive layer. Said glass sheet comprises, at a nonzero distance from the conductive layer, a periodic pattern of conductive elements that is suitable for increasing, for a predetermined frequency, the transmission of radiofrequency electromagnetic waves. Said periodic pattern is selected so as to have a transmission zero at a frequency of between substantially half and substantially double the frequency to be amplified.Type: ApplicationFiled: June 17, 2016Publication date: June 7, 2018Applicants: CENTRE TECHNIQUE DE L'INDUSTRIE DES PAPIERS, CARTONS ET CELLULOSES, UNIVERSITE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLEInventors: Alejandro NIEMBRO, Guy EYMIN-PETOT-TOURTOLLET, Emmanuel PISTONO, Pierre LEMAITRE-AUGER, Tan-Phu VUONG
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Publication number: 20180146679Abstract: A use, as antimicrobial material, of semicrystalline nano- and/or microfibrillated cellulose to which silver nanoparticles are attached, the silver nanoparticles being present in a weight amount strictly greater than 1% and strictly less than 20% relative to the total weight of said cellulose, the material being obtained with a process including at least one step of microwave irradiation of an aqueous dispersion of semicrystalline nano- and/or microfibrillated cellulose supplemented with at least one silver salt, in the presence of a reducing agent. An antimicrobial composition including such an antimicrobial material and to the application thereof for forming an antimicrobial film or coating, in particular for an article for food-processing.Type: ApplicationFiled: November 21, 2017Publication date: May 31, 2018Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPESInventors: Aurelien AUGER, Delphine BOUTRY, Elise EYMARD-VERNAIN, Arnaud GUIOT, Cecile LELONG
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Patent number: 9918856Abstract: A spacer including a first part made from a first shape memory material, and a second part made from a second shape memory material.Type: GrantFiled: June 20, 2014Date of Patent: March 20, 2018Assignee: Universite Grenoble AlpesInventors: Denis Favier, Pierre Mozer, Yohan Payan, Gabriel Antherieu, Nathanael Connesson
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Publication number: 20180070988Abstract: A minimally invasive system for dynamic correction of a spinal deformity in patients includes: a flat ligament made of synthetic material, a plurality of staples intended to be anchored on a respective vertebral body of the patient to hold the ligament against each vertebral body, and a device for mechanically tensioning the ligament.Type: ApplicationFiled: April 13, 2016Publication date: March 15, 2018Applicant: UNIVERSITE GRENOBLE ALPESInventors: Aurélien COURVOISIER, Ahmad EID, Jacques GRIFFET
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Patent number: 9907860Abstract: This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Said organic molecule comprises a 5 to 21 amino acid anionic polypeptide. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.Type: GrantFiled: October 23, 2015Date of Patent: March 6, 2018Assignees: INSTITUT PASTEUR, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE PARIS-SUD, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Francoise Baleux, Hugues Lortat-Jacob, David Bonnaffe, Yves-Marie Coic
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Publication number: 20180056057Abstract: The invention concerns a method of forming a medical device, the method comprising: forming a graphene film (100) over a substrate (204); depositing, by gas phase deposition, a polymer material covering a surface of the graphene film (100); and removing the substrate (204) from the graphene film (100), wherein the polymer material forms a support (102) for the graphene film (100).Type: ApplicationFiled: March 9, 2016Publication date: March 1, 2018Applicants: Centre National de la Recherche Scientifique, UNIVERSITE GRENOBLE ALPESInventors: Dipankar KALITA, Vincent BOUCHIAT, Laetitia MARTY, Nedjma BENDIAB
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Patent number: 9890368Abstract: The present invention relates to polypeptide fragments comprising an amino-terminal fragment of the PA subunit of a viral RNA-dependent RNA polymerase or variants thereof possessing endonuclease activity, wherein said PA subunit is from a virus belonging to the Orthomyxoviridae family. This invention also relates to (i) crystals of the polypeptide fragments which are suitable for structure determination of said polypeptide fragments using X-ray crystallography and (ii) computational methods using the structural coordinates of said polypeptide to screen for and design compounds that modulate, preferably inhibit the endonucleolytically active site within the polypeptide fragment. In addition, this invention relates to methods identifying compounds that bind to the PA polypeptide fragments possessing endonuclease activity and preferably inhibit said endonucleolytic activity, preferably in a high throughput setting.Type: GrantFiled: October 21, 2014Date of Patent: February 13, 2018Assignees: European Molecular Biology Laboratory (EMBL), Centre National de la Recherche Scientifique, Universite Grenoble AlpesInventors: Denis Bouvier, Thibaut Crepin, Rob Ruigrok, Aelxander Dias, Stephen Cusack
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Publication number: 20180020969Abstract: A system controls a cyclic motion of at least one body segment of an individual, including: at least one three-dimensional motion sensor, an attachment attaching the sensor to the body segment of the individual, a processor coupled to the sensor and capable of being carried by the individual, in which a reference cyclic motion and tolerance limits specific to the individual concerning at least one parameter of the motion to be controlled, which change depending on the progress thereof, are stored, the processor being configured to detect the cyclic motion, integrate the measurement data from the sensor in such a way as to calculate the parameter(s) of the motion of the segment and to compare, in real time, the parameter(s) of the measured motion (Ctr) with the parameter(s) of the previously recorded reference motion (Cref) of the individual, and a feedback device coupled to the processor, designed to provide the individual with real-time information on the compliance of the parameters(s) of the measured moType: ApplicationFiled: December 18, 2015Publication date: January 25, 2018Applicants: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Philippe CINQUIN, Vincent NOUGIER, Jacques GRIFFET, Aurélien COURVOISIER, Lucas STRUBER, Jean DUBOUSSET
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Patent number: 9876633Abstract: The invention relates to a device for the radio transmission of a data word between a transmitter (1) and a receiver (65), comprising a transmitter (1) that can transmit at least one block of data comprising a preamble word and a data word repeated several times; an elementary synchronization block allowing the synchronization of the receiver (65) to the transmitter (1) and the detection of the preamble word; and a synchronous averaging device (67) calculating the average of the data word repeated.Type: GrantFiled: April 1, 2015Date of Patent: January 23, 2018Assignee: UNIVERSITE GRENOBLE ALPESInventor: Emil Novakov
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Publication number: 20170354843Abstract: A method for measuring, monitoring, controlling, evaluating and correcting proprioceptive and/or postural and/or locomotor and/or motor and/or spatial orientation abilities of a user, includes measuring and processing in order to detect an effective movement or an effective posture of the user; comparing the effective movement or the effective posture to a theoretical movement or a theoretical posture; providing biological feedback in order to allow the user to correct his effective movement or his effective posture with respect to the theoretical movement or the theoretical posture; calculating and storing a score; transmitting the score to a third party in order to allow the latter to monitor the performances of the user; and automatically or non-automatically updating a level of difficulty.Type: ApplicationFiled: November 20, 2015Publication date: December 14, 2017Applicants: ASSOCIATION POUR LA RECHERCHE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS (ARMINES), UNIVERSITE GRENOBLE ALPES, INFOMATIQUE DE SECURITEInventors: Nicolas VUILLERME, Céline FRANCO, Bruno DIOT, Quentin MOURCOU, Anthony FLEURY
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Publication number: 20170332986Abstract: Radiographic imaging system including: an x-ray transmission unit; an x-ray receiver unit; a plate made from a material opaque to x-rays and situated between the transmission unit and the receiver unit, the plate including at least four channels, each channel enabling a part of the x-rays emitted by the transmission unit to pass through the channel; and an image processing unit configured to determine the coordinates of the projected patterns and to calculate a position of the receiver unit from the coordinates of the projected patterns and from the coordinates of the channels.Type: ApplicationFiled: November 5, 2015Publication date: November 23, 2017Applicants: UNIVERSITÉ GRENOBLE ALPES, SURGIQUAL INSTITUTE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPESInventors: Yannick GRONDIN, Philippe AUGERAT, Philippe CINQUIN, Laurent DESBAT, Benjamin SPENCER
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Publication number: 20170336242Abstract: A capacitive detection device comprising: a capacitive detector comprising a ribbon made of a dielectric material, a pair of electrodes formed on a first face of said ribbon and comprising a first electrode and a second electrode in the form of combs whose branches are arranged alternately between one another; and a third electrode in the form of a layer formed on the other face of said ribbon; and further comprising a containment electrode arranged at least partly facing and at a distance from said pair of electrodes, this containment electrode being electrically connected to said third electrode. Measurement devices including this capacitive detection device are also disclosed.Type: ApplicationFiled: May 16, 2017Publication date: November 23, 2017Applicant: Universite Grenoble AlpesInventor: Pierre Jean-Yves Thibault