Abstract: The invention discloses an AlCrVTiSiON nano-gradient coating with surface pre-oxidation and a preparation method thereof, belonging to the technical field of coatings. The AlCrVTiSiON nano gradient coating is prepared by arc ion plating technology, wherein the target materials are selected from metal Cr target, V target, AlCrSi target and AlTiSi target. In order to further improve the heat resistance of the coating and increase the cutting amount during service, the AlCrVTiSiON nano-gradient coating with O element content increasing from inside to outside was formed. The prepared coating has good heat resistance, which is suitable for high-speed cutting and improves processing efficiency.

Abstract: A microfluidic device includes a microfluidic channel formed in the microfluidic device and defined by a floor and a ceiling positioned vertically above the floor, wherein the microfluidic channel includes at least one fluid inlet configured to receive a fluid flow and at least one fluid outlet, and wherein at least one of the ceiling and the floor of the microfluidic channel is sloped relative to a horizontal plane.

Abstract: The spin-orbit torque-based random number generator includes a spin torque generation layer including a first spin torque layer and a second spin torque layer, a magnetization-free layer, a tunnel barrier layer, and a magnetization pinned layer, wherein the second spin torque layer is disposed between the magnetization-free layer and the first spin torque layer and generates field-like torque (FLT) and damping-like torque (DLT) related to the magnetization direction of the magnetization-free layer; the first spin torque layer adjusts a torque ratio according to the size of field-like torque to the size of damping-like torque in conjunction with the thickness of the second spin torque layer; in the magnetization-free layer, a magnetization direction is randomly aligned up or down based on the adjusted torque ratio; and a random number is generated based on current that is switched and output based on the randomly aligned magnetization direction.

Abstract: A method and system are arranged for fact checking electronically posted claims. The system includes an input/output device for inputting a textual complex claim as a natural language statement with a combination of two or more facts and outputting an indication that the textual complex claim is true or false. A processor connected to the input/output device generates, by a program generation module, a reasoning program for the input complex claim as a sequence of reasoning steps, where each step directs to a function in a set of sub-task functions. The processor generates, by a program execution module, each step in the reasoning program to a respective sub-task function and executes the respective sub-task function in order to provide the outputted indication.

Abstract: To accurately perform movement control of a moving body, a machine tool includes a feed driver that moves a moving body in the machine tool, a feedback controller that feedback-controls the feed driver in accordance with a state variable, a friction compensator that, to compensate for rolling friction that occurs in the feed driver, adds, in advance, a friction compensation value obtained from measurement data of rolling friction or a friction compensation value calculated using a rolling friction model to a command value to be input to the feed driver, and a reverse response reducer that reduces, using the state variable of the feedback controller, a reverse response that occurs due to addition of the friction compensation value.

Abstract: A first-dimension-guided differential scaling algorithm of the contour plot in comprehensive two-dimensional gas chromatography (2D GC) system is developed by incorporating both 1D and 2D chromatograms obtained by first and second detectors. This differential scaling method is shown to significantly improve 2D GC results in terms of retention time accuracy and consistency, peak width and hence peak capacity, and analyte quantification accuracy, which are inevitably affected by the modulation period and phase shift in modulation when the conventional contour plot reconstruction methods. Furthermore, the differential scaling method is shown to better handle the coelution and missing peak issues often encountered in the conventional methods. Finally, the differential scaling method exhibits high versatility in detector selection, which greatly broadens the 2D GC utility and can be easily adapted to other 2D chromatography systems.

Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods for modulating autophagy for treatment and prevention of autophagy-associated diseases, disorders, or conditions and compositions of photoreactive compounds. An aspect of the present disclosure provides for autophagy enhancing agents capable of treating or preventing diseases, disorders, or conditions in which autophagy is implicated.

Abstract: A robot arm having a series of rigid links including a first rigid link and a final rigid link, the links being operatively controlled via tendon-driven joints, each tendon-driven joint comprising a motorized spool configured to rotate in either of two directions and operatively coupled, via a cable assembly having an elastic portion, to a pulley configured to move a respective rigid link thereby. A controller adapts robot arm motion in response to position and force sensing signals. A tendon-driven joint may be implemented via one motor controlling the tension of two cables acting in opposing directions and coupled between respective ones of a pair of common-driven spools and a pair of pulleys.

Abstract: A novel approach for computing efficiently quantum based signal autocorrelations includes example designs associated with quantum circuits for computing the quantum autocorrelation of the signal. Importantly, to compensate for unique challenges associated with quantum signal processing (particularly regarding probabilistic measurements that result from QFT and IQFT operations), normalization and denormalization steps ensure that quantum measurement results are comparable to ranges that would be obtained with classical autocorrelation computation methods. In addition, because probabilistic measurements resulting from QFT and IQFT operations lose important phase information, lost phase information can be restored following measurement using QFT and IQFT.

Abstract: Provided herein is a see-through transparent, stable, safe and (bio)degradable hydrogel-based particulate support medium, made of calcium alginate particles. The calcium alginate particles, or hybrid hydrogel particles, are characterized by a substantially homogeneous average particle size that ranges from 0.1 micrometer to 5 micrometer.

Abstract: The present embodiments relate generally to a soft system for producing a giant magnetoelastic effect. In some embodiments, the soft system is composed of platinum-catalyzed silicone polymer matrix and neodymium-iron-boron nanomagnets. The soft system shows up to four times more enhancement of the magnetomechanical coupling factor (T/Pa) than traditional rigid counterparts owing to a distinct physical mechanism. In embodiments, the giant magnetoelastic effect is coupled with magnetic induction to implement a soft magnetoelastic generator (MEG) as an approach to biomechanical energy conversion, a technology that was heretofore conventionally challenged by low current, high internal impedance, and low water/humidity resistance for decent operation stability. This new method of biomechanical-to-electrical conversion is intrinsically waterproof since the magnetic fields are able to penetrate water with negligible intensity loss.

Abstract: A combiner includes a first unit combiner including a first primary winding connected to a first input terminal, a second primary winding connected to a second input terminal, and a first secondary winding having first and second end portions, the first end portion connected to an output terminal, wherein the first primary winding, the second primary winding, and the first secondary winding are stacked and form a first loop, a second unit combiner including a third primary winding connected to a third input terminal, a fourth primary winding connected to a fourth input terminal, and a second secondary winding having third and fourth end portions, the third end portion connected to the output terminal, wherein the third primary winding, the fourth primary winding, and the second secondary winding are stacked and form a second loop, and a third secondary winding connected between the first and fourth end portions.

Abstract: Provided are humanized anti-HLA-A2 antibodies. In certain aspects, the humanized anti-HLA-A2 antibodies are capable of constituting an antigen binding domain of a chimeric antigen receptor (CAR), where the CAR is capable of being expressed in a human cell such that the CAR specifically binds to HLA-A2. Also provided are CARs that include the humanized anti-HLA-A2 antibodies. Modified cells including the antibodies and CARs, as well as methods of using such modified cells are also provided.

Abstract: A photoelectric fluid field cluster catalytic method for atomic-scale deterministic processing, comprises the following steps: selecting nanoparticles with photocatalytic activity as a photocatalytic medium, and using a photoreduction method to realize the precipitation of metal nanoparticles on a surface of the photocatalytic medium, thus creating photoelectrocatalytic clusters; illuminating a coupling area between a surface to be processed of a workpiece, the photoelectrocatalytic clusters and a flexible tool with a catalytic light source, and simultaneously applying a bias voltage to a conductive tray of the workpiece; and applying a normal load to a flexible tool head and setting a rotation speed to generate a hydrodynamic pressure to drive a polishing solution to flow, thus enabling controllable removal with atomic-level precision.

Abstract: Reaction assemblies, reactor systems including the same, and associated methods are disclosed. In an example, a reaction assembly includes a reaction assembly housing, a moving bed region, a gas acceleration region, and a reactive bed region. The gas acceleration region includes a nozzle configured to accelerate a reaction gas and one or more downcomer regions defined between the nozzle and the reaction assembly housing. A flow of reaction gas is accelerated within the gas acceleration region to produce a fluidizing gas flow to facilitate a chemical reaction between the reaction gas and reaction particles within the reactive bed region. A reactor system can include a reactor enclosure, a reaction particle inlet, a reaction gas inlet, and a reaction assembly. A method can include introducing a flow of reaction particles and a flow of reaction gas into a reactor enclosure and flowing the reaction gas in contact with the reaction particles.

Abstract: The present disclosure provides compounds of Formula (I) or a salt, enantiomer, stereoisomer, solvate, isotopically enriched analog, prodrug, or polymorph thereof, and uses thereof. The present disclosure also provides pharmaceutical compositions comprising, as an active ingredient, the compound of Formula (I) or a salt, enantiomer, stereoisomer, solvate, isotopically enriched analog, prodrug, or polymorph thereof, and uses thereof. The series of compounds designed and synthesized in the present disclosure can effectively prevent and/or treat diseases or disorders associated with NAMPT.

Abstract: A device for multi-energy field induced atomic-scale CNC machining in an environmental atmosphere comprises an electromagnetic shielding chamber and a control mechanism, wherein an environmental chamber is arranged in the electromagnetic shielding chamber, a workpiece platform is arranged at the bottom of the environmental chamber, and a nanotool driven by a nanotool actuator is arranged at the top of the environmental chamber, and a gas inlet and a gas outlet which are connected to the environmental chamber are formed in the electromagnetic shielding chamber; and the control mechanism is used for controlling the workpiece platform and the nanotool actuator and applying energy fields including a force field, a temperature field, an electric field, an optical field and a magnetic field. The device has the advantages of atomic precision, high efficiency, low cost and good universality.

Abstract: The present invention relates to methods and compositions for transplanting non-lymphoid tissues into lymphoid organs. It may be used to cultivate organ tissues including for the purpose of supplementing or reconstituting organ function. Tissues that may be propagated in this manner include but are not limited to lung, kidney, thyroid, intestine, and brain.

Abstract: The present application relates to the field of power equipment detection devices, and in particular to a power transformer fault detection device, which includes a detection component for detecting the oil composition of the transformer, and also includes a rotating part comprising multiple groups of oil pools that are evenly spaced around the rotating axis of the rotating part. The multiple groups of oil pools are connected to oil outlets at different heights on the transformer, and a light-transmitting window is provided on the oil pool. A detection component is installed on the rotating part, and can detect the composition of the liquid in the oil pool through the light-transmitting window. The present application has the effect of allowing staff to monitor the working status of the transformer in a timely manner and reducing the labor burden of the staff.

Abstract: Various implementations described herein relate to devices, systems, and methods for inducing and/or causing cellular migration and uses thereof. Implementations described herein can be used to cause a portion of a cell population to migrate in response to a differential stimulus. Implementations described herein can be used to isolate and characterize the portion of the cell population. Implementations described herein can be used for research, diagnostic, or therapeutic purposes.