Abstract: A method includes preparing an alkyl-modified graphene oxide, injecting the modified graphene oxide into a well, and inhibiting acid-induced corrosion of a steel surface in the well with the modified graphene oxide. A composition includes an alkyl-modified graphene oxide having one or more alkyl functional group covalently bonded to a graphene core through an oxygen-containing linking group. A method of preparing modified graphene oxide includes mixing graphite powder with an oxidant to provide a mixture, adding the mixture to an acid solution including H2SO4, H3PO4, or a combination thereof to provide graphene oxide, and reacting the graphene oxide with an alkyl halide by nucleophilic substitution to provide the alkyl-modified graphene oxide.

Abstract: Provided herein are novel AAV capsids and recombinant AAV vectors comprising the same. In certain embodiment, vectors comprising a novel AAV capsid show improved transduction of cardiac tissue and/or reduced targeting of liver tissue compared to a prior art AAV capsid.

Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of tumors, containing a novel pyrazolopyrimidine compound or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition is administered in combination with other anticancer agents, and thus can be effectively used as a composition for preventing or treating cancer.

Abstract: The present invention relates to peptides derived from COVID-19 virus envelope protein and spike protein. The invention further relates to polynucleotides and vectors encoding said peptides, and antibodies and chimeric antigen receptors that bind to said peptides. The invention also relates to methods of diagnosis and prediction of conditions in a subject which leverage recognition of said peptides, such as by antigen-specific T cells.

Abstract: Isolated or recombinant anti-EGFL6 monoclonal antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer.

Abstract: A durable solid and liquid repellant material is provided having an elastomeric matrix with a plurality of lubricating domains distributed therein formed by a partial crosslinking reaction between an elastomeric precursor having a first reactive functional group and a polyol having a second reactive functional group. The polyol has a limited solubility circle. The first reactive functional group is selected from the group consisting of: alkene, amine, carboxylic acid, hydroxyl, isocyanate, and combinations thereof and the second reactive group is selected from the group consisting of: amine, carboxylic acid, hydroxyl group, and combinations thereof. The partially crosslinked elastomeric matrix has a crosslink density of greater than or equal to about 200 mol/m3 and less than or equal to about 2,000 mol/m3. Methods for forming the durable solid and liquid repellant material are also provided.

Abstract: Trans-splicing RNA (tsRNA) The invention concerns a trans-splicing RNA (tsRNA) molecule comprising at least one or multiple unstructured target binding domains complementary to at least one or multiple precursor messenger RNA (pre-mRNA) targets and adapted to prevent off-target trans-splicing by the inclusion of a safety domain; a cell or vector or therapeutic or composition or pharmaceutical composition comprising said tsRNA; and a method for killing cells or treating a disease or for imaging or for a cosmetic application using said tsRNA. The invention has use in the medical, cosmetic, and veterinary field.

Abstract: An imaging structure identification system includes an optical imaging system configured to illuminate a liquid biopsy sample for a subject. The liquid biopsy sample has one or more biological structures that are labeled with one or more fluorophores associated with a fluorescence assay for a disease state allowing detection of emitted electromagnetic radiation from the liquid biopsy sample as image data. The system also includes a processing system configured to identifying the subject as being at reduced risk for having the disease state if the subject profile is similar to the first predetermined profile for subjects not being in the disease state. However, if the subject profile is not similar to the first predetermined profile for subjects not being in the disease state it is not determinative if the subject is in the disease state.

Abstract: An electrode including a substrate, a binding compound, and a composite. The composite includes jute-activated carbon and a nickel-cobalt-layered double hydroxide (NiCoLDH). Particles of the NiCoLDH are in the form of nanoflowers with an average size of 5-15 ?m. The nanoflowers comprise nanosheets with an average thickness of 5-20 nm. The particles of the jute-activated carbon are in the form of interconnected nanosheets, which form a porous carbon framework. The porous carbon framework connects the nanoflowers, thereby forming an interconnected structure in the composite. A mixture of the composite and the binding compound is coated on the surface of the substrate. The electrode can be included in supercapacitors and power banks.

Abstract: A machine-readable medium includes instructions. The instructions, when read and executed by a processor, cause the processor to, at a client, receive an instruction to authenticate use of a server application through a host, obtain login credentials for the server application on the host, generate a machine-readable code to represent the login credentials, and display the machine-readable code to log in to the server application through the host.

Abstract: A method of manufacturing a color-routing element, may include: generating an initial pattern; performing blurring on the initial pattern to generate a reference pattern; performing edge detection on the reference pattern to generate at least one comparison pattern reflecting a process error; performing a simulation to obtain at least one color-routing figure of merit based on the reference pattern and the at least one comparison pattern; updating the initial pattern based on a calculation result of the at least one color-routing figure of merit; generating the updated initial pattern as a target pattern of the color-routing element; and manufacturing the color-routing element based on the target pattern.

Abstract: The objective of the present invention is to provide a composition for preventing, improving or treating respiratory diseases, comprising a Persicaria pubescens extract as an active ingredient, and the present invention was completed by confirming the effect of the Persicaria pubescens extract on activating the cell viability of human bronchial epithelial cells (BEAS-2B cells).

Abstract: Fluidic systems, devices and methods are provided for separating and sequestering particles from a fluid flow within traps in a fluidic chip is provided. The fluidic platform is particularly suited for parallel live zebrafish embryo studies providing automated zebrafish embryo trapping and flow through culture as well as whole mount zebrafish antibody staining functions. The zebrafish on a chip testing platform uses a chaotic hydrodynamic trapping process to trap and retain zebrafish embryos in a consistent body orientation (i.e., head pointed inward) without any external adjustments. The system and apparatus can also be adapted to be a multifunctional concentration gradient generator (CGG) that can be used to automatically immobilize dechorionated zebrafish embryos and generate chemical gradients for acute fish embryo toxicity (FET) tests.

Abstract: A method for determining mediators on the association between adverse childhood experiences and suicidal ideation of older adults according to an embodiment of the present disclosure, which is a method for determining mediators on the association between adverse childhood experiences of older adults, as an independent variable, and suicidal ideation, as a dependent variable, may include a data measurement step of measuring data for adverse childhood experiences, suicidal ideation, mental health mediators, physical health mediators, social relationship mediators, and covariates; and a statistical analysis step of estimating adjusted effects and crude effects of the mental health mediators, physical health mediators, and social relationship mediators on the suicidal ideation using a logistic-regression analysis and analyzing three path models respectively using mental health mediators, physical health mediators, and social relationship mediators, which are sets of multiple mediators.

Abstract: A process equipment system of hydraulic oil circuit blocks and an automated production line thereof, which relates to the field of mechanical processing technology. In view of the problem of low production efficiency in the positioning and processing of hydraulic oil circuit blocks, based on the six-point positioning principle, the workpiece is achieved the six-point positioning by the support components, positioning devices, and clamping devices on the upper layer of the base. The clamping device is capable to move along the chain, so as to adjust and change the clamping position, and can achieve processing five surfaces through one-time clamping of oil circuit blocks, improving positioning accuracy and processing efficiency, meeting the needs of automated production.

Abstract: A cathode material includes a Mo-doped sodium metal phosphate represented by Na4Mn1-xMoxV(PO4)3, in which x is greater than 0 and x is 0.2 or less. A sodium ion battery includes a cathode, an anode, a separator between the cathode and the anode, and an organic electrolyte, in which the cathode includes the cathode material. The cathode material has the advantage of low cost and easy preparation and also has the performance of high capacity under high current density when applied to the sodium ion battery.

Abstract: A highly sensitive technology enabling selective recognition of aflatoxins such as in contaminated cereal samples. Methods for the synthesis of AgNP-containing MIP membranes from the monomer mixtures containing both methacrylate monomers and oligomers as well as AgNOs solution in dimethylformamide enable the detection system. The AgNP were formed in the structure of the polymeric membranes during the pre-heating step followed by the UV-initiated polymerization. The highly selective sensor elements where MIP membranes are combined with the Ag nanostructures as signal amplifiers (LSPR-MIP nanochips) can be stored separately and used with a simple optical recognition system as selective elements of point-of-care sensor devices, even in in-field conditions. Composite plasmonic membranes provide both highly selective recognition of the target toxin and the generation of an enhanced optical signal, allowing aflatoxin B1 detection at ultralow concentrations.

Abstract: Aspects of the present disclosure are directed to a method for synthesizing carbon quantum dots. The method includes reacting a mixture of a fruit waste material and deionized water hydrothermally in an autoclave at a reaction temperature in a range of 150° C. to 250° C. to form a carbon quantum dot containing suspension, centrifuging the carbon quantum dot containing suspension to separate the carbon quantum dots from a hydrochar, and filtering the carbon quantum dot containing suspension to obtain the carbon quantum dots. The carbon quantum dots have a size ranging from 2 to 10 nm. The carbon quantum dots have a Stokes shift of at least 150 nm at an excitation wavelength of 360 nm or lower.

Abstract: A method for fault diagnosis of a pressure sensor of an electro-hydraulic system with an explicit controller and an implicit controller in parallel is provided. The method may include receiving parameter information of the electro-hydraulic system; estimating a first chamber pressure of the hydraulic actuator online by utilizing a second chamber pressure of the hydraulic actuator; obtaining valve opening signals of the explicit controller and the implicit controller in a valve controller; converting the valve opening signals are difference-calculated to obtain two residual signals; and the residuals of an independent metering valve 1 and an independent metering valve 2 are compared with a preset threshold, respectively, to identify whether the independent metering valve 1 and the independent metering valve 2 are faulty or not. The method is simple to operate, has a fast response time and low cost for troubleshooting, and improves the diagnostic accuracy and coverage of the electro-hydraulic system.

Abstract: A method of upcycling polymers to useful hydrocarbon materials. A catalyst with nanoparticles on a substrate selectively docks and cleaves longer hydrocarbon chains over shorter hydrocarbon chains. The catalyst includes metal nanoparticles in an order array on a substrate.