Abstract: The present disclosure relates generally to the field of cancer immunotherapy. More particularly, the present disclosure provides antibody recruitment molecules, pharmaceutical compositions comprising same and kits comprising same. The present disclosure also provides methods of treating cancer using the antibody recruitment molecules in combination with oncolytic virus therapy, and methods for enhancing the efficacy and/or reducing the toxicity of the oncolytic virus therapy.

Abstract: Disclosed is an apparatus for inputting a combined photoacoustic/ultrasonic image, which generates 3D image information for a object by performing 2D scanning on the object by a first linear motion of a photoacoustic probe and an ultrasonic probe, and a second linear motion perpendicular to the first linear motion, the apparatus comprising: a transfer unit that move the photoacoustic probe and the ultrasonic probe with respect to the object in the first and/or second direction; a photoacoustic unit that outputs a laser to the object, receives a first ultrasound from the object by the laser, and generates a photoacoustic image signal; an ultrasonic unit that outputs an ultrasound to the object, receives a second ultrasound from the object by the ultrasound, and generates an ultrasonic image signal; and a main controller that combines photoacoustic image and ultrasonic image to generate a combined photoacoustic/ultrasonic image.

Abstract: The present invention provides quaternary ammonium cyclodextrin and a preparation method and uses thereof, as well as a silver nanoparticle-cyclodextrin complex and a preparation method and uses thereof. The quaternary ammonium cyclodextrin of the present invention is introduced with an amine group and quaternary ammonium groups, while retaining the special structure and properties of cyclodextrin itself. The amine group contained in the structure plays a role in reducing and complexing Ag+ in the synthesis of AgNPs, and plays a certain role in stabilizing nanoparticles and forming a complex in combination with quaternary ammonium groups.

Abstract: Provided herein are compositions suitable for treating chemically induced eye damage comprising (a) a nonsteroidal anti-inflammatory drug (NSAID), (b) a histone deacetylase (HDAC) inhibitor and (c) an angiotensin converting enzyme (ACE) inhibitor and, optionally, (d) a water-soluble vitamin. Methods of using provided compositions to treat ocular toxicity and corneal damage following exposure to chemical agents (e.g., mustard gas) are also provided.

Abstract: The present disclosure provides compounds, complexes, compositions, and methods for the detection of cancer. Specifically, the compounds, complexes, compositions of the present technology include pH (low) insertion peptides. Also disclosed herein are methods of using the complexes and compositions of the present technology in diagnostic imaging to detect cancer in a subject.

Abstract: A drilling fluid includes an aqueous base fluid; 1 to 30 wt. % of an okra composition; 10 wt. % of clay particles; and 0.005 to 0.5 wt. % of a base, each wt. % based on a total weight of the drilling fluid composition. The okra composition is uniformly disposed on surfaces of the clay particles. The clay particles disposed with the okra composition are present in the drilling fluid composition in the form of a composite. A pellet made from the clay particles treated with the okra composition has a swelling value at least 75% less than a swelling value of the pellet in an aqueous composition that does not contain the okra composition, as determined by a linear swell meter. A method of making the drilling fluid composition.

Abstract: The present invention provides a mitochondrial function-improving agent containing a lactic acid bacterium belonging to Lactobacillus farciminis or Pediococcus acidilactici, a culture of the lactic acid bacterium, or a culture supernatant of the lactic acid bacterium.

Abstract: The present disclosure provides a method for extracting a Lactarius Hatsudake Tanaka polysaccharide compound, and relates to the field of active substance extraction.

Abstract: A method of making a hydrogel by treating a cellulosic biomass containing pectin and protein with an aqueous acidic solution at a pH, at a temperature, and for a time sufficient to cause formation of at least a gel fraction containing the hydrogel.

Abstract: Methods for producing allograft tissue by applying an antimicrobial solution to allograft tissue. The antimicrobial solution exhibits antimicrobial activity to make allograft resistant to microbial organisms, such as bacterium. Surface-modified tissue grafts prepared by these methods are also disclosed.

Abstract: The present disclosure relates to compositions and methods for restoring enamel, e.g., on tooth surfaces.

Abstract: Disclosed are phototunable hydrogels, compositions that include the same, and methods for using the same for treating wounds and/or injuries, for inhibiting formation of scar tissue at wound sites, for inhibiting fibrosis in subjects in need thereof, for inhibiting lung fibrosis and/or scarring in subject in need thereof, for inhibiting formation of myofibroblasts from fibroblasts, and for inhibiting expression of ?-smooth muscle actin (?-SMA) and/or type I collagen in fibroblasts.

Abstract: The present invention utilizes 3D printing technology, specifically fused filament fabrication (FFF) 3D printing, to produce solid dosage forms, such as pharmaceutical tablets. The production process utilizes novel printing filaments, typically on a spool, which contain the active ingredient. Such active-containing filaments have proved to be extremely robust and the principles outlined in the present disclosure provide access to a variety of viable formulations directly from a 3D printer. This, for the first time, affords a viable means for the in situ (e.g. within a pharmacy) 3D printing of personalized medicines tailored to a patient's needs. The invention also relates to purpose-built software for operating the printing apparatus, as well as local, national and global systems for monitoring the real time operation of a plurality of printing apparati to enable facile detection of malfunctions, thereby making regulatory approval viable and facilitating regulatory compliance.

Abstract: Disclosed is an inductive coupling system and method for adaptive control of power transfer for a wireless three-dimensional stacked chip package. The system includes a slave chip and a master chip connected via inductive coupling; the system for adaptive control of power transfer herein shifts a load feedback voltage received by the slave chip into a feedback voltage data codeword through a level decision circuit, and the system can load the feedback voltage data codeword onto a data link of the system and feedback same to the master chip. In the present disclosure, the master chip includes a DPID control circuit controls a voltage-controlled oscillator and a frequency divider to adjust the frequency of an input clock in an energy transfer system so as to achieve adaptive control of the transmitting power of a transmitting chip.

Abstract: A method is to be implemented by a computing device that stores a risk assessment model, and includes steps of: obtaining an entry of target physiological data and target magnetic resonance imaging (MRI) images of a brain of a subject with mild cognition impairment (MCI); obtaining, based on the target MRI images, voxel values respectively of primitive voxels that are related to grey matter of the brain of the subject; selecting, from among the primitive voxels, any primitive voxel satisfying a filtering criterion as a selected voxel; calculating an average of the voxel value(s) respectively of the selected voxel(s) to obtain an average target voxel value; and obtaining a probability of the subject developing Alzheimer's disease within a predetermined time period by feeding the average target voxel value and the entry of target physiological data into the risk assessment model.

Abstract: The disclosure belongs to the technical field of additive manufacturing, and discloses a flexible piezoelectric sensor based on 4D printing. The sensor includes a magnetic part and a conductive part, wherein: the conductive part includes two substrates disposed opposite to each other and a spiral structure disposed between the two substrates. Both the two substrates and the spiral structure are made of conductive metal materials. The magnetic part has a flexible porous structure and is arranged between the two substrates to generate a magnetic field. When the two substrates are subjected to external pressure, the spiral structure and the magnetic part are compressed simultaneously, the magnetic flux passing through the spiral structure changes, and the voltage of the two substrates changes, by measuring the voltage change of the two substrates to reflect the change of external pressure, the pressure measuring process is achieved.

Abstract: Structures and methods operable to detect radiation are described. The structure includes a dual-layer detector imaging device that permits one-shot of x-rays for dual-energy imaging. In one embodiment, a front layer of the detector includes a photon counting detector and aback layer of the detector includes an an x-ray radiation source for absorbing x-ray radiation to separate radiation into low energy and high energy components for incidence upon an imaging object. In an embodiment, the imaging object includes a contrast agent material having a characteristic K-edge atomic energy band level, and the separation filter absorbing the X-ray radiation is near the K-edge atomic energy band level.

Abstract: A transformational energy efficient technology using ionic liquid (IL) to couple with monoethanolamine (MEA) for catalytic CO2 capture is disclosed. [EMmim+][NTF2?] based catalysts are rationally synthesized and used for CO2 capture with MEA. A catalytic CO2 capture mechanism is disclosed according to experimental and computational studies on the [EMmim+][NTF2?] for the reversible CO2 sorption and desorption.

Abstract: An apparatus for collecting a nasal specimen includes a device body with a nozzle at a distal end of the device body. The nozzle is configured to interface with a nasal cavity. The apparatus further includes an irrigation path and a collection path within the device body. The collection path may be separate from the irrigation path. The irrigation path is configured to direct a fluid from an irrigation chamber into the nasal cavity in order to dislodge a sample from the nasal cavity. When the fluid flows back out of the nasal cavity, the collection path is configured to direct at least a portion of the fluid and the sample dislodged from the nasal cavity into a collection chamber.

Abstract: A process for separating carbon dioxide from acetylene utilizes a CHA-type zeolite membrane.