Abstract: A system and method that determines whether a heat exchanger within a complex networked system is fouling is provided. The system and method includes training classifiers indicative of a plurality of fouling conditions associated with the heat exchanger and testing the classifiers with optimal sensor data from optimal sensors to determine whether the fouling is being experienced by the heat exchanger.

Abstract: The present disclosure provides advantageous sheet stabilized emulsion based inks, and improved methods for fabricating and using such inks. More particularly, the present disclosure provides improved methods for fabricating conductive inks derived from water-in-oil emulsions stabilized by sheets exfoliated from layered materials (e.g., substantially pristine and non-oxidized graphite or hexagonal boron nitride), and related methods of use. A layered material (e.g., substantially pristine and non-oxidized graphite or hexagonal boron nitride) can be exfoliated into individual sheets, and these sheets can be utilized to stabilize water-in-oil emulsions. In certain embodiments, by utilizing long chain alkanes (e.g., hexadecane), one can advantageously fabricate emulsions with high viscosity and stability. In this form, the emulsions can be used as inks, thereby advantageously providing an inexpensive route to printing electrically conducting and/or insulating lines and shapes.

Abstract: The present disclosure is directed to a system and method for handling data in an underwater acoustic sensors network, the system comprises a low power computing system configured to function underwater, the computing system including a processor and a memory in communication with the processor, wherein the memory stores a set of instructions executable by the processor, the set of instructions when executed by the processor, cause the processor to receive a primary data from a plurality of master nodes; process the primary data using one or more data reduction algorithms to obtain a resultant data, wherein the resultant data is of a reduced size than the primary data; perform some generic computations on the resultant data, and transmit the resultant data to a gateway.

Abstract: The disclosure provides compounds of the formula I and the pharmaceutically acceptable salts thereof. The variables, e.g. R1, R2, R3, R4, A, B, J, V, W, M, J and Ar are defined herein. The disclosure also provides pharmaceutical compositions comprising a compound or salt of formula I and a pharmaceutically acceptable carrier, methods of inhibiting dihydrofolate reductase (DHFR) in vitro or in vivo with a compound or salt of formula I, and methods of treating a bacterial infections, fungal infections, and protozoal infections with a compound or salt of formula I. A compound or salt of formula I can be the first and only active ingredient used in a pharmaceutical composition or method of this disclosure or may be combined with one or more additional active ingredients that are not compounds or salts of formula I.

Abstract: Described are devices, systems and techniques for implementing atomic memory objects in a multi-writer, multi-reader setting. In an embodiment, the devices, systems and techniques use maximum distance separable (MDS) codes, and may be specifically designed to optimize a total storage cost for a given fault-tolerance requirement. Also described is an embodiment to handle the case where some of the servers can return erroneous coded elements during a read operation.

Abstract: A fluid analysis device can include a fluid inlet opening configured to receive a test fluid, and one or more fluid distribution channels in fluid communication with the fluid inlet opening and configured to receive and distribute the test fluid from the fluid inlet opening using a passive self-loading mechanism. The device can include a plurality of assays fluidly isolated from each other and configured to receive the test fluid from the one or more fluid distribution channels.

Abstract: The disclosure provided herein relates generally to mesenchymal-like stem cells “hES-T-MiSC” or “T-MSC” and the method of producing the stem cells. The method comprises culturing embryonic stem cells under conditions that the embryonic stem cells develop through an intermediate differentiation of trophoblasts, and culturing the differentiated trophoblast in hES-T-MSC or T-MSC, T-MSC derived cells and cell lineages “T-MSC-DL” are also described. Disclosed also herein are solutions and pharmaceutical compositions comprising the T-MSC and/or T-MSC-DL, methods of making the T-MSC and T-MSC-DL, and methods of using the T-MSC and T-MSC-DL for treatment and prevention of diseases, specifically. T-MSC and T-MSC-DL are used as immunosuppressive agents to treat multiple sclerosis and autoimmune diseases.

Abstract: Hybrid organic/inorganic coating compositions of nanometer thickness are described, where the organic layer is a clay-containing layer comprising a clay and a hydrophilic polymer and the inorganic layer is a metal-containing layer comprising a metal with a refractive index greater than 1.5, where the coating compositions allow for the generation and tenability of iridescent color through control of the coat thickness.

Abstract: The present disclosure includes systems and methods for capture a whole slide image of a sample. In exemplary embodiments, a camera is configured to capture a digital image of a sample. The system captures a bright field image of the sample, and captures a digital image of the sample illuminated from a first incident angle at a first wavelength and a second incident angle at a second wavelength. The system can determine whether the sample is defocused based on the transitional shift between a first wavelength channel and a second wavelength channel of the captured digital image. The system can determine the defocus distance based on the transitional shift and autofocus using the defocus distance such the bright field image is in focus.

Abstract: The present disclosure provides advantageous graphene/graphite stabilized composites (e.g., graphene/graphite stabilized emulsion-templated foam composites), and improved methods for fabricating such graphene/graphite stabilized composites. More particularly, the present disclosure provides improved methods for fabricating pristine, graphene/graphite/polymer composite foams derived from emulsions stabilized by graphene/graphite kinetic trapping. In exemplary embodiments, the present disclosure provides that, instead of viewing the insolubility of pristine graphene/graphite as an obstacle to be overcome, it is utilized as a means to create or fabricate water/oil emulsions, with graphene/graphite stabilizing the spheres formed. These emulsions are then the frameworks used to make foam composites that have shown bulk conductivities up to about 2 S/m, as well as compressive moduli up to about 100 MPa and breaking strengths of over 1200 psi, with densities as low as about 0.25 g/cm3.

Abstract: In an embodiment, a hydrogen monitoring system comprises a plurality of sensing elements that individually comprise a working electrode, a counter electrode, an insulating layer located in between the working electrode and the counter electrode, a catalyst located on an end of both the working electrode and the counter electrode, an electrolyte located on the end of the sensing elements on both the working electrode and the counter electrode, between the working electrode and the counter electrode, and in contact with the catalyst, and an electrical circuit located on an opposite end of the sensing element that connects the working electrode and the counter electrode.

Abstract: A mechanochromic system comprising a first inorganic/polymer composite layer; and a first elastomer layer bonded to the composite layer to form a composite/elastomer assembly, methods of making, and methods of use thereof are provided.

Abstract: This disclosure provides a unique approach for the synthesis of non-stoichiometric, mesoporous metal oxides with nano-sized crystalline wall. The as-synthesized mesoporous metal oxide is very active and stable (durability >11 h) electocatalyst in both acidic and alkaline conditions. The intrinsic mesoporous metal oxide serves as an electrocatalyst without the assistant of carbon materials, noble metals, or other materials, which are widely used in previously developed systems. The as-synthesized mesoporous metal oxide has large accessible pores (2-50 nm), which are able to facilitate mass transport and charge transfer. The as-synthesized mesoporous metal oxide requires a low overpotential and is oxygen deficient. Oxygen vacancies and mesoporosity served as key factors for excellent performance.

Abstract: Thermal barrier coatings and methods to make such coatings present improved resistance to CMAS infiltration. The method for forming a thermal barrier coating includes applying a layer of the thermal barrier coating to a component having a surface, forming a plurality of first channels in the thermal barrier coating, and forming a plurality of second channels in the thermal barrier coating. The first channels extend through a thickness of the thermal barrier coating from an interface with the surface of the component to a free surface opposite the interface. The second channels are disposed between the free surface and the interface and extending lengthwise generally parallel to the free surface of the thermal barrier coating.

Abstract: Devices, computer-readable media, and methods for differential adaptive bitrate streaming based on scene complexity are disclosed. In one example, a method includes inferring, by a processor, a complexity of a scene contained in a first chunk of an adaptive bitrate streaming video, wherein the first chunk is a next chunk of the adaptive bitrate streaming video to be downloaded to an adaptive bitrate streaming video player, and wherein the complexity indicates a relative amount of spatial and temporal information contained in the scene, and selecting, by the processor, a first track from which to download the first chunk, wherein the first track is one of a plurality of tracks containing the first chunk, and wherein each track of the plurality of tracks encoded the first chunk at a different bitrate, and wherein a bitrate of the first track is proportional to the complexity of the scene as inferred.

Abstract: The invention provides a drug conjugate comprising: 1) a therapeutic agent that comprises a phosphate, phosphonate, carboxy, or phosphoramidate group, and 2) a fluorescent group linked to the phosphate, phosphonate, carboxy, or phosphoramidate group to form the corresponding ester and salts thereof. The conjugates are useful for therapy and as probes. The invention also provides therapeutic methods for treating diseases with conjugates of the invention as well as methods for determining optimal dosages of a conjugate or a therapeutic agent for a given patient using a conjugate of the invention.

Abstract: A mesoporous metal doped cerium oxide catalyst is provided. The catalyst can contain nanotextured cerium oxide (CeO2) which can be utilized for hydrogen production or reformate gas purification in a water gas shift reaction. The catalyst may be advantageously used to remove CO from a gas containing CO. The catalyst may also be incorporated into a fuel processor.

Abstract: A computer-implemented method includes recording one or more demonstrations of a task performed by a user. Movements of one or more joints of the user are determined from the one or more demonstrations. By a computer processor, a neural network or Gaussian mixture model incorporating one or more contraction analysis constraints is learned, based on the movements of the one or more joints of the user, the one or more contraction analysis constraints representing motion characteristics of the task. A first initial position of a robot is determined. A first trajectory of the robot is determined to perform the task, based at least in part on the neural network or Gaussian mixture model and the first initial position.

Abstract: To predict a failure condition in a power module of a vehicle, it is determined whether a discontinuity in statistical data characterizing physical measurements of the power module meets a threshold criterion. Responsive to the discontinuity meeting the threshold criterion, a data offset in the physical measurements is computed at the discontinuity. A shift correction is applied to the physical measurements in accordance with the computed data offset responsive to a determination that the discontinuity is attributable to a restart of the power module. Other statistical data characterizing the shift-corrected physical measurements are computed and the statistical data and the other statistical data are provided to a machine learning processor that predicts the failure condition in the power module.

Abstract: A wearable 3D augmented reality display and method, which may include 3D integral imaging optics.