Abstract: Systems and methods of auto-encoder behavior modelling of vehicle components are described herein. A method for electronic device health prediction may include encoding input data into a reduced feature set via an auto-encoder as part of an artificial neural network. The method may further include decoding the reduced feature set. The method may also include reading the reduced feature set as output. The method may still further include encoding features of a subject device and other devices, wherein at least one of the other devices is designated as a healthy device. The method may additionally include associating the features of the other devices with a healthy device cluster based on a threshold distance. The method may also additionally include associating the features of the subject device with the healthy device cluster, wherein the subject device is flagged as faulty based upon exceeding the threshold distance from the healthy device cluster.
Type:
Application
Filed:
January 15, 2020
Publication date:
July 15, 2021
Applicants:
TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., UNIVERSITY OF CONNECTICUT
Inventors:
Donald McMenemy, John Kaminski, Shailesh N. Joshi, Ali M. Bazzi, Krishna Pattipati
Abstract: Systems and methods of testing the health of vehicular power devices are disclosed herein. A method may include producing operating points as a function of cycling current (Ids) and voltage drain to source (Vds) when a subject device is conducting current. The method may further include determining a mean of moving distribution to adapt a center of the moving distribution contrasted with a plurality of known healthy devices. The method may also include indicating an imminent fault in the subject device based upon a discontinuity among operating points above a threshold.
Type:
Application
Filed:
January 15, 2020
Publication date:
July 15, 2021
Applicants:
TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., UNIVERSITY OF CONNECTICUT
Inventors:
Donald McMenemy, John Kaminski, Shailesh N. Joshi, Ali M. Bazzi, Krishna Pattipati
Abstract: A computer-implemented method includes recording, with a three-dimensional camera, one or more demonstrations of a user performing one or more reaching tasks. Training data is computed to describe the one or more demonstrations. One or more weights of a neural network are learned based on the training data, where the neural network is configured to estimate a goal location of the one or more reaching tasks. A partial trajectory of a new reaching task is recorded. An estimated goal location is computed, by a computer processor, by applying the neural network to the partial trajectory of the new reaching task.
Abstract: A Factor VIII (FVIII) composition formulated such that NaCl is not present in the final formulation or is present in trace amounts, which allows for a concomitant reduction in the lyophilization cycle time and increased stability of the lyophilized FVIII.
Type:
Grant
Filed:
August 21, 2019
Date of Patent:
June 1, 2021
Assignees:
Baxalta Incorporated, Baxalta GmbH, University of Connecticut
Inventors:
Michael Pikal, Serguei Tchessalov, Erik Bjornson, Feroz Jameel, Marc Besman
Abstract: The present invention relates to a therapeutic polypeptide and methods for its creation and use for modulating an immune response in a host organism in need thereof. In particular, the invention relates to the administration to an organism in need thereof, of an effective amount of a pre-coupled polypeptide complex comprising a lymphokine polypeptide portion, for example IL-15 (SEQ ID NO: 5, 6), IL-2 (SEQ ID NO: 10, 12) or combinations of both, and an interleukin receptor polypeptide portion, for example IL-15Ra (SEQ ID NO: 7, 8), IL-2Ra (SEQ ID NO: 9, 11) or combinations of both, for augmenting the immune system in, for example, cancer, SCID, AIDS, or vaccination; or inhibiting the immune system in, for example, rheumatoid arthritis, or Lupus. The therapeutic complex of the invention surprisingly demonstrates increased half-life, and efficacy in vivo.
Abstract: Disclosed are rootstock plants, and methods of producing the rootstock plants, characterized by improved grafting success, enhanced root growth and other performance parameters.
Abstract: The present disclosure provides advantageous composite films/coatings, and improved methods for fabricating such composite films/coatings. More particularly, the present disclosure provides improved methods for fabricating composite films by trapping at least a portion of a layered material (e.g., hexagonal boron nitride sheets/layers) at an interface of a phase separated system and then introducing the layered material to a polymer film. The present disclosure provides for the use of boron nitride layers to increase the properties (e.g., dielectric constant and breakdown voltage) of polymer films. The exemplary films can be produced by an advantageous climbing technique. Exemplary boron nitride films are composed of overlapping boron nitride sheets with a total thickness of about one nanometer, with the film then transferred onto a polymer film, thereby resulting in significant increases in both dielectric and breakdown properties of the polymer film.
Type:
Grant
Filed:
July 17, 2018
Date of Patent:
May 11, 2021
Assignee:
University of Connecticut
Inventors:
Douglas H. Adamson, Zhenhua Cui, Andrey V. Dobrynin
Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1-R4 have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful in immunotherapy as a potential treatment, or co-treatment, for cancer or infectious diseases.
Type:
Application
Filed:
March 15, 2019
Publication date:
April 22, 2021
Applicants:
UNIVERSITY OF IOWA RESEARCH FOUNDATION, UNIVERSITY OF CONNECTICUT
Abstract: An antenna electrode including a first electrode that includes a core and a first conductive surface; a second electrode that includes a second conductive surface; and an electrical tunnel junction between the first conductive surface and the second conductive surface, the tunnel junction having a gap width greater than about 0.1 nm and less than about 10 nm.
Abstract: Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
Type:
Grant
Filed:
May 9, 2017
Date of Patent:
March 23, 2021
Assignees:
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC, THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE, THE UNIVERSITY OF CONNECTICUT
Inventors:
Aida E. Rieder, Teresa B. De Los Santos, Luis L. Rodriguez, Devendra Rai, Fayna C. Diaz-San Segundo, Paul D. Hoeprich
Abstract: A moisture responsive system comprising: a thin film polymer layer, wherein the thin film polymer comprises a hydrophilic polymer; and a substrate polymer layer, wherein the substrate polymer comprises a hydrophobic elastomer; wherein the thin film polymer layer is attached to the substrate polymer layer at a bottom surface of the thin film polymer layer and the thin film polymer layer has a top surface opposing the bottom surface is provided. A method of making a moisture responsive system, comprising: applying a thin film polymer layer to a foundation; applying a substrate polymer layer on the thin film polymer layer; curing the substrate polymer layer to form a thin film polymer layer/substrate polymer bilayer; and removing the thin film polymer layer/substrate polymer bilayer from the foundation is provided. A method of using such a moisture responsive system by applying moisture to the moisture responsive system is provided.
Abstract: A thermal barrier coating for an internal combustion engine includes an insulating thermal spray coating, where a chosen material of the insulating thermal spray coating has a thermal conductivity lower than 2 W/mK in fully dense form and the chosen material includes a coefficient of thermal expansion within 5 ppm/K of a coefficient of thermal expansion of a material of a component of the internal combustion engine upon which the coating is placed.
Type:
Application
Filed:
September 8, 2020
Publication date:
March 11, 2021
Applicant:
The University of Connecticut
Inventors:
Eric Jordan, Chen Jiang, Rishi Kumar, Balakrishnan Nair
Abstract: An imaging method is provided that includes: (i) providing a microscope having a lens and an autofocusing camera positioned adjacent to the microscope; (ii) positioning an illumination source adjacent to the microscope; (iii) moving a sample to a predefined offset position and illuminating the sample; (iv) acquiring an image of the illuminated sample via the autofocusing camera; and (v) utilizing a convolution neural network to identify an in-focus position of the sample. The convolution neural network may further include an input layer, output layer, and at least one hidden layer situated between the input and output layers. The hidden layer(s) may be selected from a group consisting of a convolution layer, pooling layer, normalization layer, fully connected layer, and a combination thereof. The convolution neural network may be trained to accurately define the weight to be applied to the layer(s).
Abstract: The present disclosure provides improved viscosity measuring assemblies, and related methods of use. More particularly, the present disclosure provides advantageous measuring assemblies configured to measure the viscosity of samples/fluids (e.g., opaque or transparent liquids) using microchannels. The present disclosure provides for a viscosity measuring assembly (e.g., hand-held electronic measuring assembly) that is configured to measure the viscosity of samples/fluids (e.g., opaque or transparent Newtonian and non-Newtonian liquids, including blood, etc.), in a short period of time (e.g., within a couple of minutes) utilizing only about a droplet of fluid. The viscosity measuring assembly can include a substrate having a microchannel, a light source (e.g., a collimated low coherence light source), and a sensor (e.g., photodiode).
Type:
Grant
Filed:
May 3, 2018
Date of Patent:
February 23, 2021
Assignee:
University of Connecticut
Inventors:
George Lykotrafitis, Kostyantyn Partola
Abstract: Systems and methods for fault detection and diagnosis in a machine. The method includes selecting fault characteristic frequencies of faults, implementing the fault characteristic frequencies as modulating signals, receiving a feedback signal from at least one sensor associated with a machine, applying active modulation using the modulating signals to the feedback signal to obtain modulated signals, and monitoring for a low-frequency fault indicative component from the modulated signals.
Abstract: Devices, computer-readable media, and methods for selecting a video chunk from among a plurality of video chunks associated with a first time block of a video in accordance with a designated perceptual visual quality are disclosed. For instance, a processing system including at least one processor may obtain a selection of a designated perceptual visual quality for a video, select a video chunk from among a plurality of video chunks associated with a first time block of the video, based upon a manifest file of the video, where the video chunk is selected in accordance with the designated perceptual visual quality, and where each of the plurality of video chunks is associated with a respective perceptual visual quality. The processing system may further obtain the video chunk from a server and record the video chunk in a buffer.
Type:
Grant
Filed:
September 4, 2019
Date of Patent:
February 9, 2021
Assignees:
AT&T Intellectual Property I, L.P., The University of Connecticut
Inventors:
Subhabrata Sen, Krishna R. Pattipati, Bing Wang, Yanyuan Qin
Abstract: The present disclosure provides advantageous graphene/graphite stabilized composites (e.g., graphene/graphite stabilized emulsion-templated foam composites), and improved methods for fabricating such graphene/graphite stabilized composites. More particularly, the present disclosure provides improved methods for fabricating pristine, graphene/graphite/polymer composite foams derived from emulsions stabilized by graphene/graphite kinetic trapping. In exemplary embodiments, the present disclosure provides that, instead of viewing the insolubility of pristine graphene/graphite as an obstacle to be overcome, it is utilized as a means to create or fabricate water/oil emulsions, with graphene/graphite stabilizing the spheres formed. These emulsions are then the frameworks used to make foam composites that have shown bulk conductivities up to about 2 S/m, as well as compressive moduli up to about 100 MPa and breaking strengths of over 1200 psi, with densities as low as about 0.25 g/cm3.
Type:
Application
Filed:
October 8, 2020
Publication date:
January 28, 2021
Applicant:
University of Connecticut
Inventors:
Douglas H. Adamson, Steven Woltornist, Andrey V. Dobrynin
Abstract: Disclosed is a compound of the formula (I) or (II): wherein a f are as described herein. The compounds are useful in the activation of Type II NKT cells and in treating cancer.
Type:
Application
Filed:
March 25, 2019
Publication date:
January 28, 2021
Applicants:
The United States of America,as represented by the Secretary,Department of Health and Human Services, University of Connecticut
Inventors:
Lise H. Pasquet, Jay A. Berzofsky, Amy R. Howell, Masaki Terabe, Kaddy Camara, Stewart K. Richardson
Abstract: This invention relates to an intermediate height Sand Cherry plant known as Prunus pumila and referred to by the name ‘UCONNPP002’, with a dense mounded form that is easy to produce and exhibits reliable landscape performance and ornamental traits as shown herein and described.