Patents Assigned to University of Georgia Research Foundation, Inc.
  • Publication number: 20190281752
    Abstract: A new variety of Pennisetum alopecuroides plant named ‘Tift PA18’ produces a reduced number of seeds, making it less invasive.
    Type: Application
    Filed: March 6, 2018
    Publication date: September 12, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Wayne W. Hanna, Brian M. Schwartz
  • Patent number: 10398663
    Abstract: A mitochondria targeted gold nanoparticle (T-3-BP-AuNP) decorated with 3-bromopyruvate (3-BP) and delocalized lipophilic triphenylphosphonium (TPP) cations to target the mitochondrial membrane potential (??m) was developed for delivery of 3-BP to cancer cell mitochondria by taking advantage of higher ??m in cancer cell compared to normal cells. This construct showed remarkable anticancer activity in prostate cancer cells compared to non-targeted construct NT-3-BP-AuNP and free 3-BP. Anticancer activity of T-3-BP-AuNP was further enhanced upon laser irradiation by exciting the surface plasmon resonance band of AuNP and thereby utilizing a combination of 3-BP chemotherapeutic and AuNP photothermal effects. T-3-BP-AuNPs showed markedly enhanced ability to alter cancer cell metabolism by inhibiting glycolysis and demolishing mitochondrial oxidative phosphorylation in prostate cancer cells.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: September 3, 2019
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Shanta Dhar, Sean Marrache
  • Publication number: 20190269055
    Abstract: A new Hibiscus plant named ‘RutHib2’ is characterized by a combination of good form, medium vigor, purple foliage, magenta flowers with a red eye, and good tolerance to Alternaria, Cercospora, and Phytophthora pathogens.
    Type: Application
    Filed: February 26, 2018
    Publication date: August 29, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventor: John M. Ruter
  • Publication number: 20190269056
    Abstract: A new Hibiscus plant named ‘RutHib1’ is characterized by a combination of good form, medium vigor, predominately purple foliage, white flowers with a red eye, and good tolerance to Alternaria, Cercospora, and Phytophthora pathogens.
    Type: Application
    Filed: February 26, 2018
    Publication date: August 29, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventor: John M. Ruter
  • Publication number: 20190246541
    Abstract: A new crapemyrtle plant has deep, uniform purple foliage and stems; a true pink flower color; an intermediate upright growth habit; and powdery mildew and Cercospera resistance.
    Type: Application
    Filed: February 5, 2019
    Publication date: August 8, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Matthew A. Dirr, Donglin Zhang
  • Publication number: 20190246542
    Abstract: A new crapemyrtle plant has deep, uniform purple foliage and stems; a light lavender to white flower color; an intermediate upright growth habit; and powdery mildew and Cercospera resistance.
    Type: Application
    Filed: February 5, 2019
    Publication date: August 8, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Matthew A. Dirr, Donglin Zhang
  • Publication number: 20190246543
    Abstract: A new crapemyrtle plant has deep, uniform purple foliage and stems; a deep raspberry pink/red flower color; an intermediate upright growth habit; and powdery mildew and Cercospera resistance.
    Type: Application
    Filed: February 5, 2019
    Publication date: August 8, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Matthew A. Dirr, Donglin Zhang
  • Patent number: 10358637
    Abstract: The carbohydrate processing enzyme PNGase F was catalytically inactivated through mutation. Additional mutations yielded a catalytically inactive carbohydrate-binding protein with lectin-like properties including high affinity and specificity N-linked glycans, O-linked glycans, or both.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: July 23, 2019
    Assignees: University of Georgia Research Foundation, Inc., Glycosensors and Diagnostics, LLC
    Inventors: Kausar N. Samli, Robert J. Woods, Loretta Yang
  • Patent number: 10328182
    Abstract: Compositions, devices, grafts and methods for reducing or preventing anti-neointima following cardiovascular injuries and interventions are disclosed. The compositions, devices, and grafts typically include an effective amount of a CTP synthase 1 inhibitor to reduce proliferation of vascular smooth muscle cells, without substantial reducing the proliferation of endothelial cells. Methods of reducing neointima formation, accelerating re-endothelialization, and reducing restenosis in a subject using the compositions, devices, and grafts are also disclosed.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: June 25, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Shiyou Chen, Rui Tang
  • Patent number: 10329538
    Abstract: Attenuated isolates of the Arkansas serotype of infectious bronchitis virus (IBV), including the IBV isolate ArkGA p60 deposited at the ATCC under Patent Designation PTA-123783, and compositions thereof are presented. Methods for administering the isolates or compositions as vaccines to the prevent virulent IBV infection in birds of the order Galliformes are also presented.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: June 25, 2019
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Brian J. Jordan, Mark W. Jackwood
  • Patent number: 10329585
    Abstract: The present invention includes the Paramyxovirus Parainfluenza Virus 5 (PIV5) as an oncolytic agent for treating various cancers, including, but not limited to breast cancer, lung cancer and melanoma. PIV5 oncolytic agents include both wild type PIV5 and various recombinant PIV5 constructs. Recombinant PIV5 constructs may include PIV5 lacking the conserved C-terminus of the V protein (PIV5V?C), PIV5 with mutations in the N-terminus of the V/P protein (PIV5CPI?), and PIV5 expressing MDA-7/IL-24 (rPIV5-MDA7), rPIV5-V/P-CPI?, rPIV5-CPI+, rPIV5-Rev, rPIV5-RL, rPIV5-P-S157A, rPIV5-P-S308A, rPIV5-L-A1981D, rPIV5-F-5443P, rPIV5-MDA7, rPIV5?SH-CPI?, or rPIV5?SH-Rev. Also included are methods of making and using such oncolytic agents and compositions including such oncolytic agents.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: June 25, 2019
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventor: Biao He
  • Publication number: 20190169664
    Abstract: Host cells are metabolically engineered to consume glucose and glycerol simultaneously, and to divert glucose from catabolic to anabolic pathways without adversely affecting glucose uptake.
    Type: Application
    Filed: May 5, 2017
    Publication date: June 6, 2019
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Yajun YAN, Yifei WU, Xinxiao SUN, Yuheng LIN
  • Patent number: 10307435
    Abstract: Disclosed are compositions, articles, and method for enhancing exercise performance in a subject. The method involves contacting the oral cavity of the subject with a composition comprising a sweet and caloric food product for a period sufficient to cause a cephalic phase response in the subject.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: June 4, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventor: Jamie A. Cooper
  • Patent number: 10307106
    Abstract: Systems and methods for estimating time-dependent voltages that are induced in electrophysiological monitoring systems by magnetic field gradients generated during a magnetic resonance imaging (“MRI”) scan are provided. The gradient-induced voltages are subsequently removed from signals acquired with the electrophysiological monitoring system during an MRI scan. As an example, the electrophysiological monitoring system can include an electrocardiography (“ECG”) system, an electroencephalography (“EEG”) system, an electromyography (“EMG”) system, a voltage device tracking (“VDT”) system, and so on. The gradient-induced voltages are estimated using a two-step procedure in which a learning algorithm is used to determine fitting parameters to be used in a model of the gradient-induced voltages. The fitting parameters are then used together with the model to extract the gradient-induced voltages from signals acquired during an MRI scan. The gradient-induced voltages can then be removed from the acquired signals.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: June 4, 2019
    Assignees: BRIGHAM AND WOMEN'S HOSPTIAL, INC., UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Wei Wang, HuaLei Zhang, Ehud J. Schmidt, Tsz Ho Tse
  • Patent number: PP30724
    Abstract: A new variety of Pennisetum alopecuroides plant named ‘Tift H18’ produces a reduced number of seeds, making it less invasive.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: July 16, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Wayne W. Hanna, Brian M. Schwartz
  • Patent number: RE47539
    Abstract: Convenient methods of preparing aza-dibenzocyclooctynes are disclosed herein. Aza-dibenzocyclooctynes attached to a surface are also disclosed herein. Aza-dibenzocyclooctynes can be reacted with azides to form heterocyclic compounds. Such reactions can be useful in a wide variety of applications including, for example, labeling surfaces.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: July 30, 2019
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: Vladimir V. Popik, Alexander Kuzmin, Andrei Polukhtine
  • Patent number: PP30815
    Abstract: A new variety of Citrus ichangensis x C. maxima plant named ‘Tift2-16’ produces fruit with a reduced number of seeds, making it valuable as a backyard fruit tree. Also, it is a desirable tree for landscaping.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: August 20, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Wayne W. Hanna, Brian M. Schwartz
  • Patent number: PP30816
    Abstract: A new variety of Citrus reticulata plant named ‘Tift3-46’ produces fruit with a reduced number of seeds, making it valuable as a backyard fruit tree. Also, it is a desirable tree for landscaping.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: August 20, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Wayne W. Hanna, Brian M. Schwartz
  • Patent number: PP30824
    Abstract: A new Hibiscus plant named ‘RutHib1’ is characterized by a combination of good form, medium vigor, predominately purple foliage, white flowers with a red eye, and good tolerance to Alternaria, Cercospora, and Phytophthora pathogens.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: August 20, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventor: John M. Ruter
  • Patent number: PP30853
    Abstract: A new Hibiscus plant named ‘RutHib2’ is characterized by a combination of good form, medium vigor, purple foliage, magenta flowers with a red eye, and good tolerance to Alternaria, Cercospora, and Phytophthora pathogens.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: August 27, 2019
    Assignee: University of Georgia Research Foundation, Inc.
    Inventor: John M. Ruter