Patents Assigned to University of Manchester
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Patent number: 11143961Abstract: The present invention relates to resist compostions, in particular to photoresists that can be used in photolithography, especially in the fabrication of integrated circuits and derivative products. The resist compositions of the invention include an anti-scattering component which has a significant amount of empty space, and thus fewer scattering centers, such that radiation-scattering events are more limited during exposure. Such anti-scattering effects can lead to improved resolutions by reducing the usual proximity effects associated with lithographic techniques, allowing the production of smaller, higher resolution microchips. Furthermore, certain embodiments involve anti-scattering components which are directly linked to the resist components, which can improve the overall lithographic chemistry to provide benefits both in terms of resolution and resist sensitivity.Type: GrantFiled: September 29, 2016Date of Patent: October 12, 2021Assignee: The University of ManchesterInventors: Scott Lewis, Richard Winpenny, Stephen Yeates, Antonio Fernandez
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Patent number: 11100619Abstract: Embodiments of the invention provide a method of processing colour image data comprising receiving image data corresponding to a first and a second region of an image having colour information represented in a first colour space; converting the colour information of the image data from the first colour space to a second colour space, the mapping being arranged to substantially maintain a perceived colour of the colour information and to select a meta-brightness of the first and second regions; and out putting the image data having colour information in the second colour space.Type: GrantFiled: February 9, 2017Date of Patent: August 24, 2021Assignee: The University of ManchesterInventors: Robert James Lucas, Annette Elizabeth Allen
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Publication number: 20210198097Abstract: There is disclosed a device and method for fabricating such a device. The device includes cavities formed in a transparent substrate. A laminated membrane is mounted to the substrate and spans the cavities. The laminated membrane includes a layer of a flexible material, typically a polymer, and a layer of a two-dimensional material that is typically graphene.Type: ApplicationFiled: March 4, 2021Publication date: July 1, 2021Applicant: The University of ManchesterInventors: Aravind Vijayaraghavan, Christian Berger
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Publication number: 20210187085Abstract: The present invention relates to a non-naturally occurring peptide comprising amino acid sequence S-V-L-T-X1-E-N-X2 (SEQ ID NO: 1), wherein X1 is any amino acid and X2 is any amino acid, which may optionally be linked to an amino acid sequence X3-I-X4-X5-E-X6 (SEQ ID NO: 5), wherein, X3, X4, X5 and X6 each denote any amino acid. The present invention further relates to the use of such peptides as a medicament such as for the prevention and treatment of kidney disease and in apheresis methods.Type: ApplicationFiled: October 23, 2018Publication date: June 24, 2021Applicant: The University of ManchesterInventors: Paul BRENCHLEY, Thomas JOWITT, Maryline FRESQUET, Rachel LENNON, Sam RHODEN
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Patent number: 11034839Abstract: The present disclosure relates to compounds of the formula (1) that function as senescent cell detectors: wherein the SBB analogues refer to de novo synthesized derivatives with structural similarity to the Sudan Black B dye, L is an appropriate chemical bond and hapten is biotin, or digoxigenin, or 2,4-dinitrophenol, or fluorescein, but more preferably biotin. The present invention also relates to processes for the preparation of these compounds, to their use in the detection of senescent cells, to methods of detecting senescence in cells and to kits comprising said compounds.Type: GrantFiled: June 28, 2017Date of Patent: June 15, 2021Assignee: THE UNIVERSITY OF MANCHESTERInventors: Vassilis Gorgoulis, Paul Townsend, Panayiotis Marakos, Nikolaos Lougiakis, Nicole Pouli, Nikolaos Kastrinakis
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Publication number: 20210145933Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.Type: ApplicationFiled: January 15, 2019Publication date: May 20, 2021Applicant: THE UNIVERSITY OF MANCHESTERInventors: Paul BISHOP, Simon CLARK, Richard UNWIN
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Publication number: 20210110204Abstract: The image recognition method comprises receiving a challenge image (100); and comparing the challenge image (100) to a reference image set (400) generated from a reference image (200). The reference image set (400) comprising at least one modified reference image (401-406) having a different lighting condition to the reference image (200).Type: ApplicationFiled: March 26, 2018Publication date: April 15, 2021Applicant: The University of ManchesterInventors: Hujun Yin, James Burnstone, Shireen Zaki
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Patent number: 10959973Abstract: A method for delivering a benefit agent to the surface of the eye, the method comprising applying an ocular benefit composition to a lid margin of the eye wherein the ocular benefit composition comprises at least 5 wt % of one or more lipid and/or lipid derived compounds.Type: GrantFiled: December 14, 2016Date of Patent: March 30, 2021Assignee: The University of ManchesterInventors: Philip Morgan, Carole Maldonado-Codina, Michael Read, Curtis Dobson
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Patent number: 10961127Abstract: A method for the production of 1T-transition metal dichalcogenide few-layer nanosheets and/or monolayer nanosheets comprising electrochemical intercalation of lithium ions into a negative electrode comprising a bulk 2H-transition metal dichalcogenide to provide an intercalated electrode, and an exfoliation step comprising contacting the intercalated electrode with a protic solvent to produce 1T-transition metal dichalcogenide few-layer nanosheets and/or monolayer nanosheets. An electrochemical capacitor comprising a composite electrode comprising 1T-MoS2 nanosheets and graphene, and a method of producing a composite electrode for use in an electrochemical capacitor.Type: GrantFiled: January 23, 2018Date of Patent: March 30, 2021Assignee: The University of ManchesterInventors: Robert Dryfe, Andinet Ejigu, Ian Kinloch
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Patent number: 10947390Abstract: The present disclosure relates to de novo synthesized, chemical compounds of the formula (1) or (2) that function as senescent cell detectors wherein R1, R2, R3, R4 and Z are as defined herein. The present invention also relates to processes for the preparation of these compounds, to their use in the detection of senescent cells, to methods of detecting senescence in cells and to kits comprising said compounds. The compounds have the ability to react with lipofuscin, in an analogous manner to the histochemical dye Sudan Black B (SBB).Type: GrantFiled: June 28, 2017Date of Patent: March 16, 2021Assignee: THE UNIVERSITY OF MANCHESTERInventors: Vassilis Gorgoulis, Paul Townsend, Panayiotis Marakos, Nikolaos Lougiakis, Nicole Pouli, Nikolaos Kastrinakis
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Patent number: 10947107Abstract: There is disclosed a device and method for fabricating such a device. The device includes cavities formed in a substrate. A laminated membrane is mounted to the substrate and spans the cavities. The laminated membrane includes a layer of a flexible material, typically a polymer, and a layer of a two-dimensional material that is typically graphene.Type: GrantFiled: November 4, 2016Date of Patent: March 16, 2021Assignee: The University of ManchesterInventors: Aravind Vijayaraghavan, Christian Berger
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Patent number: 10950774Abstract: Composite materials with thermoelectric properties and devices made from such materials are described. The thermoelectric composite material may comprise a metal oxide material and graphene or modified graphene. It has been found that the addition of graphene or modified graphene to thermoelectric metal oxide materials increases ZT. It has further been found that the ZT of the metal oxide becomes effective over a broader temperature range and at lower temperatures.Type: GrantFiled: February 14, 2014Date of Patent: March 16, 2021Assignee: The University of ManchesterInventors: Robert Freer, Colin Norman, Yue Lin, Deepanshu Srivastava, Ian Kinloch
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Patent number: 10926228Abstract: The present invention relates to a method of altering the relative proportions of protons, deuterons and tritons in a sample using a membrane. The membrane comprises a 2D material and an ionomer. The invention also relates to a method of making said membranes.Type: GrantFiled: July 26, 2016Date of Patent: February 23, 2021Assignee: The University of ManchesterInventors: Marcelo Lozada, Andre K. Geim
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Patent number: 10913035Abstract: This invention relates to membranes of two dimensional material and their uses in filtration. The membranes may include polyaromatic molecules which provide a improvement in the rejection observed for small solutes. The two dimensional material may be a transition metal dichalcogenide (TMDC) or hexagonal boron nitride (hBN).Type: GrantFiled: April 5, 2017Date of Patent: February 9, 2021Assignee: The University of ManchesterInventors: Robert Dryfe, Mark Bissett
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Patent number: 10912845Abstract: The present invention relates to an improved method of providing photoreceptor function to a cell, for example for use in the treatment of retinal degeneration. The present invention also relates to compositions and kits, in particular for use in such methods.Type: GrantFiled: February 24, 2015Date of Patent: February 9, 2021Assignee: The University of ManchesterInventors: Robert Lucas, Paul Bishop, Jasmina Cehajic-Kapetanovic
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Publication number: 20200306213Abstract: Compounds, compositions and their use in the treatment or prevention of symptoms of Lowe Syndrome and Dent disease 2 are described, for instance, the use of such compounds in the treatment of Lowe Syndrome and Dent disease 2, or in the treatment or prevention of at least one symptom associated therewith.Type: ApplicationFiled: September 27, 2018Publication date: October 1, 2020Applicants: Université de Montréal, The University of Manchester, Centre National De La Recherche Scientifique, Sorbonne Université, Institut PasteurInventors: Sébastien CARRENO, Khaled Ben El Kadhi, Arnaud Echard, Clothilde Cauvin, Martin Lowe
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Publication number: 20200277360Abstract: Polypeptides comprising a C3b binding region and a C3d inactivating region are disclosed, as well as nucleic acids and vectors encoding proteolytic such polypeptides. Also disclosed are cells and compositions comprising such polypeptides, and uses and methods using the same.Type: ApplicationFiled: June 8, 2018Publication date: September 3, 2020Applicant: THE UNIVERSITY OF MANCHESTERInventors: Simon CLARK, Richard UNWIN, Paul BISHOP
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Patent number: 10752444Abstract: The present invention relates to a transfer chute (100) for granular material, comprising a chute body defining a flow pathway (120) for granular material, a raised portion (110) having an inclined surface (111), and a splitter member (130) arranged proximal to the raised portion (110) for, in use, dividing a flow of granular material over the raised portion into first portion in first conduit (100) and a second portion in a second conduit (300). In some embodiments, a channel (150) is disposed between the first and second conduits (100; 300) to transpose a vertical arrangement of first and second portions of granular material within the chute (10). In this way, separation by particle size or density in the flow may be reversed.Type: GrantFiled: July 28, 2017Date of Patent: August 25, 2020Assignee: The University of ManchesterInventor: John Mark Nicholas Timm Gray
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Publication number: 20200201174Abstract: The present invention relates to a resist composition, especially for use in the production of electronic components via electron beam lithography. In addition to the usual base polymeric component (resist polymer), a secondary electron generator is included in resist compositions of the invention in order to promote secondary electron generation. This unique combination of components increases the exposure sensitivity of resists in a controlled fashion which facilitates the effective production of high-resolution patterned substrates (and consequential electronic components), but at much higher write speeds.Type: ApplicationFiled: February 27, 2020Publication date: June 25, 2020Applicant: The University of ManchesterInventors: Scott Lewis, Stephen Yeates, Richard Winpenny
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Patent number: 10651490Abstract: The present invention relates to a graphene-based or other 2-D material membrane which allows the passage of protons and deuterons and to a method of facilitating proton or deuteron permeation through such a membrane. Monocrystalline membranes made from mono- and few-layers of graphene, hBN, molybdenum disulfide (MoS2), and tungsten disulfide (WS2) etc. are disclosed. In effect, the protons or deuterons are charge carriers that pass through the graphene or other 2-D material membrane. This process can be contrasted with the passage of gaseous hydrogen. Hydrogen is an uncharged gaseous species which is diatomic. In other words, the gas is in molecular form when considering the normal barrier properties whereas in the case of the present invention, the species which is being transported through the membrane is a charged ion comprising a single atom. Membranes of the invention find use in a number of applications such as fuel cells.Type: GrantFiled: September 15, 2015Date of Patent: May 12, 2020Assignee: The University of ManchesterInventors: Marcelo Lozada, Andre K. Geim