Abstract: Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign proliferative disorders (warts) or in the prevention of the development of cancer. Pharmaceutical compositions formulated for topical application comprising a therapeutically effective amount of lopinavir or a therapeutically effective amount lopinavir and ritonavir in a pharmaceutically acceptable vehicle are also provided. Also disclosed are methods of treating a patient having an HPV related dysplasia of the cervix comprising administering to said patient a therapeutically effective dose of the disclosed pharmaceutical compositions.

Abstract: An antenna array (106) which in use emits radiation in two respectively orthogonally polarised directions, the array including a plurality of elements, the elements including at least one element of a first type and at least four elements of a second type wherein the element of the first type comprises part of two balanced feeds with two elements of the second type and the element of the first type is capacitively coupled to two further elements of the second type, wherein the elements used to produce radiation in a first direction lie in a first plane (104), the elements used to produce radiation in a second direction lie in a second plane (102), and the first and second planes are spaced apart, and the element of the first type includes two portions, one of which lies in the first plane and one of which lies in the second plane.

Abstract: The present invention relates to an electron beam (eBeam) resist composition, particularly an (eBeam) resist composition for use in the fabrication of integrated circuits. Such resist compositions include an anti-scattering compound which minimizes scattering and secondary electron generation, thus affording extremely high resolution lithography. Such high resolution lithography may be used directly upon silicon-based substrates to produce integrated circuits, or may alternatively be used to produce a lithographic mask (e.g. photomask) to facilitate high-resolution lithography.

Abstract: Embodiments of the invention provide a method of processing colour image data comprising receiving image data corresponding to a first and a second region of an image having colour information represented in a first colour space; converting the colour information of the image data from the first colour space to a second colour space, the mapping being arranged to substantially maintain a perceived colour of the colour information and to select a meta-brightness of the first and second regions; and out putting the image data having colour information in the second colour space.

Abstract: Embodiments relate to a signal processing system and method in particular for determining the location of a feature within a hollow body using deconvolution of measured acoustic waves.

Abstract: A method for delivering a benefit agent to the surface of the eye, the method comprising applying an ocular benefit composition to a lid margin of the eye wherein the ocular benefit composition comprises at least 5 wt % of one or more lipid and/or lipid derived compounds.

Abstract: The present invention relates to an ink formulation comprising two-dimensional inorganic layered particles. The ink formulations of the present invention are for inkjet printing. The present invention also relates to a process for the preparation of these ink formulations, to the use of these ink formulations for the production of printed films and tracks comprising the inorganic material, to the films or tracks produced by the inkjet printing these ink formulations, and to devices that comprise these films or tracks.

Abstract: Embodiments of the present invention provide an electromagnetic sensor (400) for detecting a microstructure of a metal target, comprising: a magnetic device (410, 420) for providing an excitation magnetic field; a magnetometer (430) for detecting a resultant magnetic field induced in a metal target; and a calibration circuit (450, 551, 552, 553, 554) for generating a calibration magnetic field for calibrating the electromagnetic sensor, wherein the calibration reference magnetic field is generated by an electrical current induced in the calibration circuit by the excitation magnetic field.

Abstract: A biocompatible and biodegradable medical device patch actuating primarily as soft tissue structural reinforcement. The device has a layered architecture, where the primary serves as suturing layer and mechanical support to a thick porous scaffold which can be coated with a mimic-like extra cellular matrix (ECM). The device can be provided to the end user under the format of independent layers that can be cut and assembled to the specific need to the end user and patient. The layers are assembled without the need of any adhesive. Totally haemocompatible and of behavior superior to polytetrafluoroethylene used for any soft tissue repaired, the field of this invention is demonstrated for cardiovascular therapy but should not be limited to it. It is of practical relevance of vein, tendon and hernias and dermal treatments.

Abstract: There is disclosed a device and method for fabricating such a device. The device includes cavities formed in a substrate. A laminated membrane is mounted to the substrate and spans the cavities. The laminated membrane includes a layer of a flexible material, typically a polymer, and a layer of a two-dimensional material that is typically graphene.

Abstract: A method for the production of non-carbon-based 2D materials and/or non-carbon-based 2D material nanoplatelet structures having a thickness of less than 100 nm in an electrochemical cell having a negative electrode which comprises a non-carbon-based bulk 2D material and an electronically conducting material such as a metal.

Abstract: The present invention relates to a method of altering the relative proportions of protons, deuterons and tritons in a sample using a membrane. The membrane comprises a 2D material and an ionomer. The invention also relates to a method of making said membranes.

Abstract: Embodiments of the present invention provide an electromagnetic sensor (400) for detecting a microstructure of a metal target, comprising: a magnetic device (410, 420) for providing an excitation magnetic field; a magnetometer (430) for detecting a resultant magnetic field induced in a metal target; and a calibration circuit (450, 551, 552, 553, 554) for generating a calibration magnetic field for calibrating the electromagnetic sensor, wherein the calibration reference magnetic field is generated by an electrical current induced in the calibration circuit by the excitation magnetic field.

Abstract: The present invention relates to an imagable specimen sample, particularly an imagable histological sample for imaging via techniques such as scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The invention provides imaging preparation compositions, such as resin compositions, which can be embedded within a specimen sample and can also encapsulate the sample. The compositions contain either or both of a secondary electron generator and/or a self-healing component. The secondary electron generator enhances image quality by increasing the amount of secondary electron scattering. The self-healing component minimises specimen sample damage caused by the imaging technique.

Abstract: Borylated compounds are disclosed, as well as their methods of preparation and their applications. The disclosed borylated compounds are highly stable, and have reduced band gap properties, thereby making them attractive candidates for incorporation into semiconducting materials for use in a variety of electronic, optical or electro-optical devices or components.

Abstract: Embodiments of the present invention relate to a communication system and method adapted to manage interference between users of base stations.

Abstract: A multilayer sheet of cells, comprising a layer of endothelial cells, and a layer of podocytes is disclosed.

Abstract: Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign proliferative disorders (warts) or in the prevention of the development of cancer. Pharmaceutical compositions formulated for topical application comprising a therapeutically effective amount of lopinavir or a therapeutically effective amount lopinavir and ritonavir in a pharmaceutically acceptable vehicle are also provided. Also disclosed are methods of treating a patient having an HPV related dysplasia of the cervix comprising administering to said patient a therapeutically effective dose of the disclosed pharmaceutical compositions.

Abstract: This invention relates to methods of purifying water using graphene oxide laminates which are formed from stacks of cross-linked individual graphene oxide flakes. The laminates also comprise graphene and/or at least one cross-linking agent. The invention also relates to the laminate membranes themselves.

Abstract: Devices and methods for measuring an electrical characteristic, in particular, for measuring current are provided. The devices can use a pair of MEMS optical modulators as opposed to the more conventional coil and associated oil insulation arrangement.