Abstract: A material processing and associated additive manufacturing system and method that utilizes high intensity light to fuse an entire layer of material, at one time, to create a three-dimensional component. The system and method of the present invention allows for each layer to be created in a fraction of the time, thereby reducing the overall time for a three-dimensional component to be created, thereby increasing control over the properties achieved.

Abstract: Statistical models for predicting minimum number of step data of an attacker and reliability functions of a computer network system are described. The models are based on utilizing vulnerability information along with an attack graph. Using the model, it is possible to identify the interaction among vulnerabilities and individual variables or risk factors that drive the minimum number of step data. Gaining a better understanding of the relationship between the vulnerabilities and their interactions can provide security administrators with a better view and understanding of their security status.

Abstract: Disclosed are nanoparticles and nanogel drug compositions and the use thereof for treating age-related macular degeneration.

Abstract: A variety of particles forming microencapsulated thermochromic materials. The particles can include a thermochromic core and a metal oxide shell encapsulating the thermochromic core. The thermochromic core can include one or both of an organic thermochromic material and an inorganic salt thermochromic material. In some aspects, the particles include a dye selected from a crystal violet lactone dye, a fluoran dye, and a combination thereof. In still further aspects, the particles include a color developer selected from a hydroxybenzoate, a 4,4?-dihydroxydiphenyl propane, a hydroxycoumarin derivative, a lauryl gallate, and a combination thereof. In some aspects, the metal oxide shell is a TiO2 shell. The particles can be used in cements and paints and for a variety of building materials. Methods of making the particles and building materials and methods of use, for example, for removing a volatile organic carbon from a building material, are also provided.

Abstract: A cocrystal having the formula LiX.aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical compositions comprising such cocrystals, cocrystal solvates, or cocrystal hydrates, and methods of preparing such cocrystals, cocrystal solvates, or cocrystal hydrates, and such pharmaceutical compositions.

Abstract: In one embodiment, an algae cultivation system includes a basin that contains a liquid and a photobioreactor at least partially immersed in the liquid of the basin, the photobioreactor comprising a closed container including multiple panels that together define an interior space in which algae can be cultivated, at least one of the panels being transparent, the photobioreactor further comprising an inflatable float associated with the container that can be filled with a gas to change one or both of the position and orientation of the container within the liquid.

Abstract: In one embodiment, an electrochromic device includes a single active layer configured to be alternately placed in a light-transmitting state in which relatively large amounts of light can be transmitted through the active layer and a light-blocking state in which relatively small amounts of light can be transmitted through the active layer, wherein the device comprises no other layers of material that contribute to transitioning between the two states

Abstract: Methods and compositions for treating or preventing muscle wasting resulting from an underlying disease or disorder, such as cancer cachexia. A therapeutically effective amount of a ketogenic supplement—such as R,S 1,3 butanediol diacetoacetate, R,S 1,3-butanediol acetoacetate diester, derivatives thereof, or combinations thereof—is administered to a patient or subject in need. The ketogenic supplement may further include a medium chain triglyceride in combination with the ketone ester.

Abstract: Photoelectrochemical cells including a cathode including alpha-hematite and a metal dichalcogenide, an anode including a conducting polymer, and an electrolyte.

Abstract: A system for authenticating an individual's location activity includes a mobile communications device connected to a network and in electronic communication with at least one other computer. The mobile communications device is configured to authenticate the individual's presence at a location using biometric data entered by the individual. The mobile communications device has applications stored thereon to access location information for the mobile communications device using a GPS application stored on the mobile communications device and to access time information for the mobile communications device from a clock application stored on the mobile communications device. The mobile communications devices creates a digital signature that authenticates an individual's location activity by storing an encrypted digital certificate comprising a hash calculation using the biometric data, a validation key generated by authenticating the biometric data, the location information, and the time information.

Abstract: An exemplary method of indicating a condition of grout within a post-tensioned tendon involves positioning a magnet and a metallic sensing plate in close proximity to an outer surface of the post-tensioned tendon; rotating the magnet and the metallic sensing plate around the outer surface of the post-tensioned tendon; measuring an amount of magnetic forces applied to the magnet during rotation of the magnet around the post-tensioned tendon; measuring an impedance between the metallic sensing plate and metallic strands within the post-tensioned tendon during rotation of the metallic sensing plate around the post-tensioned tendon; and generating an image of a cross-section of the post-tensioned tendon indicating one or more grout conditions in spatial proximity to the metallic strands within the post-tensioned tendon based on measurement data using the magnet and the metallic sensing plate.

Abstract: Alzheimer's disease is treated using THC (alone, or in combination with melatonin) administered in an ultra-low dose amount sufficient to (i) reduce A? protein levels; (ii) reduce A? aggregation: (iii) maintain A?PP protein levels; (iv) enhance mitochondrial functioning; (v) decrease phosphorylation of GSK-3? protein; (vi) decrease GSK-3? protein levels; (vii) decrease phosphorylation of Tau protein; and/or (viii) maintain Tau protein levels, in said patient without severe psychological impairments and side effects associated with higher doses of THC.

Abstract: Provided is a method of inhibiting protein kinase C zeta/protein kinase M zeta, including contacting a sample containing an isoform of protein kinase C zeta with a compound of formula: referred to as 1-naphthol-3,6,8-trisulphonic acid, or a pharmaceutically acceptable salt thereof. In some embodiments, contacting the sample with the compound does not inhibit protein kinase C iota/lambda. In a specific example, the sample includes neural tissue, the isoform of protein kinase C zeta is protein kinase M zeta, and inhibiting includes reducing kinase activity and further includes diminishing long-term potentiation. In some embodiment, the method includes inhibiting glucose transport. Also provided is a method of affecting memory, including administering the compounds to a mammalian organism.

Abstract: Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of separating CO2 from a gas, and the like.

Abstract: Described are non-toxigenic Clostridium difficile strains and spores. Also described are vaccines comprising the Clostridium difficile spores. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.

Abstract: Described herein are compounds, formulations, and methods for blocking sporozoite invasion and subsequent liver-stage parasite development of a protozoan parasite, such as Plasmodium falciparum.

Abstract: System and method for providing patient-specific models to distinguish between epochs of electrocardiograms (ECGs) located far away from atrial fibrillation rhythms and those located just prior to the onset of those episodes, to provide for the prediction of the onset of an occurrence of atrial fibrillation (AF) in the patient.

Abstract: Alzheimer's disease is treated using THC (alone, or in combination with melatonin) administered in an ultra-low dose amount sufficient to (i)reduce A? expression; (ii) reduce A? aggregation: (iii) maintain APP expression; (iv) enhance mitochondrial functioning; (v) decrease phosphorylation of GSK3? protein; (vi) decrease the expression of GSK3? protein; (vii) decrease phosphorylation of Tau protein; and/or (viii) maintain Tau protein expression, in said patient without severe psychological impairments and side effects associated with higher doses of THC.

Abstract: Described herein are compositions composed of frustrated Lewis pairs impregnated in porous materials such as, for example, metal-organic frameworks, and their uses thereof. These compositions may allow new applications of frustrated Lewis pairs in catalysis by sequestering and protecting the frustrated Lewis pair within the nanospace of the porous material. Also provided are methods of hydrogenating an organic compound having at least one unsaturated functional group comprising using the compositions described herein.

Abstract: The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.