Patents Assigned to University of Tsukuba
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Patent number: 11944579Abstract: A biological activity detection apparatus includes: a drive unit that actively or passively drives in conjunction with a limb motion of a subject; a periarticular detection unit that detects a periarticular physical quantity around a joint in association with the limb motion of the subject based on an output signal from the drive unit; a biological signal detection unit located at a body surface site of the subject with reference to the joint and includes an electrode group for detecting a biological signal of the subject, wherein an activity status of a musculoskeletal system and/or a transmission status of a peripheral nervous system around the joint are converted into quantitative musculoskeletal system data and/or nervous system data on the basis of the physical quantity acquired from the periarticular detection unit and a myogenic potential signal and a neural transmission signal which are acquired from the biological signal processing unit.Type: GrantFiled: August 24, 2017Date of Patent: April 2, 2024Assignees: CYBERDYNE Inc., University of TsukubaInventor: Yoshiyuki Sankai
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Publication number: 20240099631Abstract: This apparatus (1) comprises at least one intravascular device (10), (20) that is disposed in a blood vessel of an organism and that is equipped with at least one electrode (11), (12), (21), (22) for detecting or stimulating the activity of nerve tissue positioned outside the blood vessel nearby, the electrodes (11), (12), (21), (22) being provided on a wire member.Type: ApplicationFiled: January 17, 2022Publication date: March 28, 2024Applicants: E.P.MEDICAL INC., UNIVERSITY OF TSUKUBAInventor: Yuji MATSUMARU
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Carbon nanotube assembled wire, carbon nanotube assembled wire bundle, and carbon nanotube structure
Patent number: 11939219Abstract: The carbon nanotube assembled wire includes a plurality of carbon nanotubes oriented at a degree of orientation of 0.9 or more and 1 or less.Type: GrantFiled: December 26, 2019Date of Patent: March 26, 2024Assignees: SUMITOMO ELECTRIC INDUSTRIES, LTD., UNIVERSITY OF TSUKUBAInventors: Toshihiko Fujimori, Takeshi Hikata, Soichiro Okubo, Jun-ichi Fujita -
Patent number: 11934558Abstract: A distributed data integration device includes an acquisition unit configured to acquire, for a piece of analysis target data, an anchor data intermediate representation and an analysis target intermediate representation, the anchor data intermediate representation being an intermediate representation obtained by converting anchor data by a first function, the anchor data being data commonly used in integration of a plurality of the pieces of analysis target data that are distributed, the analysis target intermediate representation being an intermediate representation obtained by converting the analysis target data by the first function, an anchor data conversion unit configured to convert, for the piece of analysis target data, a plurality of the anchor data intermediate representations by a second function, a calculation unit configured to calculate, for the piece of analysis target data, the second function that minimizes a difference between the plurality of the anchor data intermediate representations, aType: GrantFiled: December 18, 2019Date of Patent: March 19, 2024Assignee: University of TsukubaInventors: Akira Imakura, Tetsuya Sakurai
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Publication number: 20240088394Abstract: A secondary battery of the present disclosure includes a positive electrode, an electrolyte layer, a negative electrode current collector, and metallic lithium as a negative electrode active material that is deposited between the electrolyte layer and the negative electrode current collector by charging, an intermediate layer is present between the electrolyte layer and the negative electrode current collector, and the intermediate layer contains hydrogen boride.Type: ApplicationFiled: September 6, 2023Publication date: March 14, 2024Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, UNIVERSITY OF TSUKUBAInventors: Ximeng LI, Takahiro Kondo
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Patent number: 11925437Abstract: A photoacoustic imaging apparatus comprises: a light emitting unit emitting pulsed light with a wavelength absorbed inside a subject; a thin, flexible film applied to a skin surface of the subject to make the pulsed light transmit it and reflects the light on its outer surface at the same time; a multi-directional light emitting unit emitting a plurality of visible light beams from multi-directions to the outer surface of the thin film; a micro-vibration detection unit detects, on the basis of diffraction and/or interference of a plurality of reflected light obtained from the outer surface of the thin film, a state of causing micro-vibrations of the thin film as the photoacoustic waves generated from the light absorber collide against an inner backside of the thin film; and a shape image transformation unit that produces the images of a shape of the light absorber as detected by the micro-vibration detection unit.Type: GrantFiled: July 24, 2019Date of Patent: March 12, 2024Assignee: CYBERDYNE INC., UNIVERSITY OF TSUKUBAInventor: Yoshiyuki Sankai
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Publication number: 20240029434Abstract: A non-transitory computer-readable recording medium has stored therein a program that causes a computer to execute a process, the process including acquiring movie data including a plurality of consecutive frames calculating first likelihood of a class of the movie data by inputting the acquired movie data to a trained model, calculating an optical flow indicating movement of an area included in the movie data, based on the movie data generating occluded movie data by setting an occluded area in each of the frames included in the movie data, based on the optical flow, calculating second likelihood of a class of the occluded movie data by inputting the occluded movie data to the model identifying an area that affects identification of the class among areas in the movie data, based on the first likelihood and the second likelihood and displaying the identified area that affects identification of the class.Type: ApplicationFiled: July 19, 2022Publication date: January 25, 2024Applicants: FUJITSU LIMITED, University of TsukubaInventors: Tomoki UCHIYAMA, Naoya SOGI, Koichiro NIINUMA, Kazuhiro FUKUI
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Patent number: 11876542Abstract: A compression apparatus performs processing of registering a symbol, which is input, in a predetermined entry among a plurality of entries in a case where the symbol is not registered in a first table having the plurality of entries and outputting the symbol and index data indicating non-compression, processing of outputting index data indicating compression and positional information indicating a position of the entry having the symbol registered therein and having a size smaller than a size of the symbol in a case where the symbol has been registered in the table, and processing of changing the size of the positional information depending on usage conditions of the plurality of entries.Type: GrantFiled: April 28, 2020Date of Patent: January 16, 2024Assignee: UNIVERSITY OF TSUKUBAInventors: Shinichi Yamagiwa, Koichi Marumo, Eisaku Hayakawa
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Patent number: 11866330Abstract: A method for manufacturing a carbon nanotube includes: a mist generating step of generating a mist including a catalyst particle and a liquid carbon source; and a growing step of growing a carbon nanotube from the catalyst particle by heating the mist.Type: GrantFiled: February 18, 2020Date of Patent: January 9, 2024Assignees: SUMITOMO ELECTRIC INDUSTRIES, LTD., UNIVERSITY OF TSUKUBAInventors: Takeshi Hikata, Toshihiko Fujimori, Soichiro Okubo, Jun Otsuka, Jun-ichi Fujita
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Publication number: 20240000829Abstract: An objective of the present invention is to provide a self-assembled polymer micelle-type ornithine donor, which has high bioavailability, low toxicity, and high therapeutic effectiveness, even when provided by oral administration. Another objective of the present invention is to provide a self-assembled polymer micelle-type ornithine donor which is effective in preventing or treating hepatic disorders. In order to achieve the above objectives, an acyl group is introduced into the primary amino group in the side chain of an ornithine unit in the poly(ornithine) segment of poly(ethylene glycol)-b-poly(ornithine), which spontaneously forms polymer micelles without polyion complex formation.Type: ApplicationFiled: November 9, 2021Publication date: January 4, 2024Applicant: University of TsukubaInventors: Yukio NAGASAKI, Yaroslav LEE, Long Binh VONG, Yuta KODA, Yuanyuan DING
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Publication number: 20240003913Abstract: Biomarkers for detecting cognitive dysfunction diseases and methods for detecting cognitive dysfunction diseases using the biomarkers are provided. A method for detecting cognitive dysfunction diseases comprising measuring one or more biomarkers for detecting cognitive dysfunction diseases selected from the following (a), (b), and (c) in a biological sample simultaneously or separately: (a) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of apolipoprotein A1 comprising the amino acid sequence represented by SEQ ID NO:1 or a partial peptide thereof; (b) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of transthyretin comprising the amino acid sequence represented by SEQ ID NO:2 or a partial peptide thereof; and (c) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of complement C3 comprising the amino acid sequence represented by SEQ ID NO:3 or a partial peptide thereof.Type: ApplicationFiled: July 12, 2023Publication date: January 4, 2024Applicants: MCBI INC., UNIVERSITY OF TSUKUBAInventors: Kazuhiko UCHIDA, Kohji MENO, Hideaki SUZUKI, Yoshinori NISHIMURA
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Publication number: 20230403143Abstract: A secure computation system comprising secure computation server apparatuses, each of which comprises: a discriminant share generation part that computes discriminant shares configured so that an index relating to an input corresponds to a specific value from shares representing the index relating to the input and possible combinations of index shares of an array; a combination configuration part that configures a combination of shares of an element in the array and the discriminant shares for all possible combinations of indices of the array; a shuffle part that shuffles the combinations; a reconstruction part that reconstructs the discriminant shares in the shuffled combinations; and a selection part that selects shares of an element in the array in the combinations where the reconstructed value is the specific value.Type: ApplicationFiled: November 20, 2020Publication date: December 14, 2023Applicants: NEC CORPORATION, UNIVERSITY OF TSUKUBAInventors: Hikaru TSUCHIDA, Takashi NISHIDE
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Publication number: 20230364303Abstract: [Object] Provided is a method of producing a nerve fascicle including efficiently extending axons of neural cells. [Solution] Neural cells are cultivated in the presence of feeder cells including at least one type of cells selected from the group consisting of vascular component cells, perivascular cells, and oligodendrocytes.Type: ApplicationFiled: September 17, 2021Publication date: November 16, 2023Applicant: University of TsukubaInventors: Hiroshi ISHIKAWA, Aiki MARUSHIMA, Yuji MATSUMARU, Masao KODA, Akira MATSUMURA, Hiroki BUKAWA, Akihiro OHYAMA, Junko TOYOMURA, Miho WATANABE, Tetsuya ABE, Shohei TAKAOKA, Yosuke SHIBAO, Hideaki MATSUMURA
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Publication number: 20230346125Abstract: A rocking device includes: a seat which supports a body of a user; a motor which rotates a rotation shaft in a first rotation direction and in a second rotation direction that is a rotation direction opposite to the first rotation direction, and thereby supplies motive power for rocking the seat via a gear attached to the rotation shaft; and a controller which controls rocking of the seat via the motor. The seat is configured to make a first motion of moving in a first movement direction, in accordance with rotation of the rotation shaft in the first rotation direction, and make a second motion of moving in a second movement direction, in accordance with rotation of the rotation shaft in the second rotation direction. The controller is configured to control rocking of the seat such that a prescribed stopped period is provided between the first motion and second motion.Type: ApplicationFiled: April 13, 2023Publication date: November 2, 2023Applicants: TOYOTA BOSHOKU KABUSHIKI KAISHA, UNIVERSITY OF TSUKUBAInventors: Yasuhiro KATO, Akio SHIMIZU, Takahiro HARITA, Takashi ABE
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Patent number: 11787037Abstract: [Problem] Learning of object operation skills robust against variation of conditions is implemented. [Solution] A behavior estimation apparatus 100 includes a collection unit 200 configured to collect skill data obtained when a slave robot is operated under a plurality of different conditions by using a bilateral system capable of operating the slave robot via a master robot through bidirectional control between the master robot and the slave robot. The behavior estimation apparatus 100 further includes a behavior estimation device 300 configured to estimate a command value for causing the slave robot 520 to automatically behave, based on the skill data collected by the collection unit 200 and a response output from the slave robot 520.Type: GrantFiled: March 20, 2019Date of Patent: October 17, 2023Assignee: University of TsukubaInventor: Sho Sakaino
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Publication number: 20230316700Abstract: An information processing apparatus acquires an image; generates a shielding image in which a part of an area included in an area of the acquired image has been shielded; calculates, by inputting the image to a first model that has been trained, first likelihood of the target object included in the image; calculates, by inputting the shielding image to a second model that calculates an approximation value of likelihood of the target object included in the image when the image is input, second likelihood corresponding to the approximation value of the likelihood of the target object included in the shielding image; specifies, based on the first likelihood and the second likelihood, an area that affects discrimination of the class and that is included in the area of the image; and displays the specified area that affects discrimination of the class.Type: ApplicationFiled: March 31, 2022Publication date: October 5, 2023Applicants: FUJITSU LIMITED, University of TsukubaInventors: Naoya SOGI, Tomoki UCHIYAMA, Kazuhiro FUKUI, Koichiro NIINUMA
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Patent number: 11774447Abstract: This invention provides a method for diagnosis of rheumatoid arthritis of a subject, a method for assisting diagnosis of rheumatoid arthritis, and a method for monitoring disease activity of rheumatoid arthritis and/or therapeutic effects of an agent for rheumatoid arthritis, comprising detecting citrullination of an arginine residue of the inter-?-trypsin inhibitor heavy chain (ITIH) 4 in a biological sample obtained from the subject. This invention also provides a citrullinated protein derived from the protein having the amino acid sequence as shown in SEQ ID NO: 1 or 5 by modification of arginine 438 into citrulline or a fragment thereof, an antibody binding to such citrullinated protein, and an agent for diagnosis of rheumatoid arthritis comprising such antibody.Type: GrantFiled: July 2, 2018Date of Patent: October 3, 2023Assignee: University of TsukubaInventors: Isao Matsumoto, Takayuki Sumida, Hoshimi Kawaguchi
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Patent number: 11759104Abstract: In a scanning imaging apparatus of some aspect examples, a scanner applies an optical scan to a sample to acquire data. A scan controller controls the scanner to sequentially apply, to the sample, pattern scans according to a two-dimensional pattern including cycles. A movement unit relatively moves a scan area corresponding to the two-dimensional pattern and the sample. A movement controller controls the movement unit such that cycles in first and second scans of the pattern scans cross each other. An image constructing unit constructs an image based on data acquired under controls performed by the scan controller and the movement controller. The scan controller and the movement controller perform controls of the scanner and the movement unit respectively such that first and second cycles in a pattern scan cross each other at least at one point.Type: GrantFiled: September 7, 2020Date of Patent: September 19, 2023Assignees: UNIVERSITY OF TSUKUBA, TOPCON CORPORATIONInventors: Yoshiaki Yasuno, Shuichi Makita, Tatsuo Yamaguchi, Toshihiro Mino
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Patent number: 11746316Abstract: Proposed are a three-dimensional structuring method of cells and a three-dimensional structuring system of cells capable of efficiently bonding multiple cell clusters in a three-dimensional direction, pursuant to their growth, while ensuring safety. A plurality of fibers, in which one end of each of the fibers is held by a flat plate, are inserted together with the flat plate into a flow path through which a culture solution is supplied, a plurality of cell clusters are placed in the flow path upon causing the cell clusters to run with a liquid flow of the culture solution, and each of the cell clusters is cultured by being stacked on an outer surface of each of the fibers with the flat plate as a growth origin.Type: GrantFiled: June 9, 2017Date of Patent: September 5, 2023Assignees: CYBERDYNE Inc., University of TsukubaInventor: Yoshiyuki Sankai
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PARAMYLON-BASED RESIN, MOLDING MATERIAL, MOLDED BODY, AND METHOD FOR PRODUCING PARAMYLON-BASED RESIN
Publication number: 20230272123Abstract: A paramylon-based resin having a weight-average molecular weight of paramylon in a range of 70000 to 140000, and formed by substituting hydrogen atoms of hydroxy groups of a paramylon with a long-chain component being a linear saturated aliphatic acyl group having 14 or more carbon atoms and a short-chain component being an acyl group (acetyl group or/and propionyl group) having 2 or 3 carbon atoms, wherein a degree of substitution with the long-chain component (DSLo) and a degree of substitution with the short-chain component (DSSh) satisfy the following conditional expressions (1) and (2), Izod impact strength is 5.0 kJ/m2 or more, and an MFR (melt flow rate at 210° C. and under a load of 5 kg) is 2 g/10 min or more. To provide a paramylon-based resin excellent in mechanical characteristics and thermoplasticity. 2.2?DSLo+DSSh?2.Type: ApplicationFiled: April 20, 2023Publication date: August 31, 2023Applicants: NEC CORPORATION, UNIVERSITY OF TSUKUBAInventors: Midori SHIMURA, Shukichi Tanaka, Toshie Miyamoto, Masatoshi Iji