Patents Assigned to University of Tsukuba
-
Publication number: 20230169627Abstract: A model learning unit determines a model parameter for calculating an estimated value for each of a plurality of training sets, each including a measurement signal and at least one type of predetermined characteristic value indicating characteristics of the measurement signal as a target value, to minimize a difference between the estimated value calculated for the measurement signal using a predetermined mathematical model and the target value is minimized, determines characteristic value sets, each being a set of a plurality of types of characteristic values indicating characteristics of the measurement signal including the target value, with which, for each target value, the target value is common to a plurality of characteristic value sets, and generates, for each of the characteristic value sets, each of the plurality of training sets including the target value and a measurement signal having characteristics indicated by the plurality of types of characteristic values.Type: ApplicationFiled: April 6, 2021Publication date: June 1, 2023Applicant: University of TsukubaInventors: Yoshiaki YASUNO, Thitiya SEESAN
-
Patent number: 11654035Abstract: A gait disorder support apparatus and gait disorder support method capable of detecting an onset sign of a gait disorder associated with motor symptoms in advance and performing motion assist are proposed. The onset sign of the gait disorder associated with the motor symptoms of a wearer is detected based on the correlation between a gait cycle and a reduction ratio of the gait cycle as compared to immediately preceding gait; and when the onset sign of the gait disorder is detected, a drive unit is controlled so that the drive unit applies assist power to a knee joint of the wearer; and on the other hand, when the onset sign of the gait disorder is not detected, the drive unit is controlled so that driving torque by the drive unit does not hinder the wearer's gait motion.Type: GrantFiled: March 17, 2017Date of Patent: May 23, 2023Assignees: CYBERDYNE Inc., University of TsukubaInventor: Yoshiyuki Sankai
-
Publication number: 20230106845Abstract: A trained model generation program causes a computer to implement a learning execution function of inputting first input image data representing a first input image generated by a first reconstruction method using compressed sensing and second input image data representing a second input image generated by a second reconstruction method different from the first reconstruction method to a machine learning device to execute machine learning, the second reconstruction method being an analytical reconstruction method, and causing the machine learning device to generate a trained model, and a trained model acquisition function of acquiring trained model data indicating the trained model. Then, input image data representing an input image is input to the trained model to generate a reconstructed image with improved image quality.Type: ApplicationFiled: February 24, 2021Publication date: April 6, 2023Applicant: University of TsukubaInventors: Hiroyuki KUDO, Kazuki MORI
-
Patent number: 11607126Abstract: A biopotential can be measured with high accuracy without the electrodes coming into direct contact with the skin and without being affected by any motion artifact. The present invention comprises a first lead which detects a biopotential containing noise components, a second lead which is electrically isolated from the first lead and detects noise components, and a differential amplifier circuit which is input with a first signal output from the first lead and a second signal output from the second lead, and which amplifies and outputs a difference between the first signal and the second signal, wherein a value of an input impedance on the second signal side of the differential amplifier circuit is set so that the noise components detected from the second lead will have a frequency that is higher than a frequency spectrum of the biopotential.Type: GrantFiled: June 1, 2015Date of Patent: March 21, 2023Assignees: University of Tsukuba, CYBERDYNE Inc.Inventors: Yoshiyuki Sankai, Alexsandr Igorevitch Ianov
-
Patent number: 11583820Abstract: A hydrogen generator includes a reaction vessel, a water supply, a temperature adjustor, and a controller. The reaction vessel houses a hydrogen generating material having hydrogen generating ability. The hydrogen generating material includes a two-dimensional hydrogen boride sheet having a two-dimensional network and containing multiple negatively charged boron atoms. The controller is configured to execute a hydrogen generating mode to generate hydrogen from the hydrogen generating material and a regenerating mode to recover the hydrogen generating ability of the hydrogen generating material. The controller controls the temperature adjustor to heat the hydrogen generating material at a first predetermined temperature during the hydrogen generating mode. The controller controls the temperature adjustor to adjust the temperature of the hydrogen generating material to a second predetermined temperature and controls the water supply to supply water during the regenerating mode.Type: GrantFiled: September 29, 2021Date of Patent: February 21, 2023Assignees: DENSO CORPORATION, University of Tsukuba, TOKYO INSTITUTE OF TECHNOLOGYInventors: Yasuyuki Hikita, Hiroaki Yoto, Takahiro Kondo, Shin-ichi Ito
-
Publication number: 20220402756Abstract: The present invention provides a hydrogen storage and release material including a two-dimensional hydrogen boride-containing sheet including a two-dimensional network containing n(HxBy) (n?4, 0.001?x/y?0.999) having a molar ratio of boron to hydrogen from 1:0.999 to 1:0.001, the molar ratio being determined by thermal desorption spectroscopy, and mass measurement before and after a temperature rise, wherein the hydrogen storage and release material has: peaks derived from B1s of boron at 187.5±1.0 eV and 191.2±1.0 eV to 193±1.0 eV in X-ray photoelectron spectroscopy, and a peak derived from a B—H stretching vibration at from 2400 cm?1 to 2600 cm?1 and also a peak derived from a B—H—B stretching vibration at from 1200 cm?1 to 1800 cm?1 in infrared spectroscopy.Type: ApplicationFiled: November 6, 2020Publication date: December 22, 2022Applicants: University of Tsukuba, Tokyo Institute of TechnologyInventors: Takahiro Kondo, Ryota Ishibiki, Taiga Goto, Shin-Ichi Ito, Yoshihiro Kinoshita
-
Publication number: 20220323761Abstract: A method for inducing a hibernation-like state and a device for the same is described. The method is a chemical and physical method for reducing, in a subject, a theoretical set-point temperature of a body temperature and/or a feedback gain of heat production, or for inducing a hibernation-like state in the subject, the method including applying an excitatory stimulus to pyroglutamylated RFamide peptide (QRFP)-producing neurons. A device used to implement the method is also described.Type: ApplicationFiled: September 30, 2020Publication date: October 13, 2022Applicant: University of TsukubaInventors: Takeshi SAKURAI, Toru TAKAHASHI, Genshiro SUNAGAWA
-
Publication number: 20220241308Abstract: Provided is a neuronal function modulating agent effective for neuronal cell protection and exerts a neuronal function modulating effect through neuronal cell protection. The disclosed neuronal function modulating agent comprises malvidin-3,5-diglucoside as an active ingredient, the disclosed pharmaceutical composition comprises the neuronal function modulating agent, and the disclosed food composition comprises the neuronal function modulating agent.Type: ApplicationFiled: May 22, 2020Publication date: August 4, 2022Applicants: University of Tsukuba, National Institute of Advanced Industrial Science and Technology, ZEON CORPORATIONInventors: Hiroko ISODA, Kazunori SASAKI, Kazuhiko SATO, Masumi ASAKAWA, Kenichi TOMINAGA, Hiroshi FUJISAWA, Masami KOSHIYAMA
-
Publication number: 20220233626Abstract: Provided is a grape pericarp extract that exhibits neuronal function modulating effects. The grape pericarp extract comprises 15 mg/g or more of malvidin-3,5-diglucoside in dry mass.Type: ApplicationFiled: May 22, 2020Publication date: July 28, 2022Applicants: University of Tsukuba, National Institute of Advanced Industrial Science and Technology, ZEON CORPORATIONInventors: Hiroko ISODA, Kazunori SASAKI, Kazuhiko SATO, Masumi ASAKAWA, Kenichi TOMINAGA, Hiroshi FUJISAWA, Masami KOSHIYAMA
-
Publication number: 20220226479Abstract: There is provided technology for promoting permeation of a substance into a cell layer. Provided is a cell layer permeation promoter comprising a compound represented by general formula (1). Also provided is a composition for facilitating drug absorption that contains the cell layer permeation promoter, said composition being for facilitating absorption of a drug into a living body. Also provided is a pharmaceutical composition that contains the cell layer permeation promoter and furthermore contains a drug to be absorbed into a living body.Type: ApplicationFiled: March 19, 2020Publication date: July 21, 2022Applicants: University of Tsukuba, Tokyo University of Pharmacy and Life SciencesInventors: Takeo USUI, Yoko NAGUMO, Minagi MUKAIYAMA, Yoshio HAYASHI, Atsuhiko TANIGUCHI, Chihiro UCHIYAMA
-
Publication number: 20220156932Abstract: Provided are a skin disease analysis program, a skin disease analysis method, a skin disease analyzer, and a skin disease analysis system, which can analyze skin disease more accurately.Type: ApplicationFiled: March 26, 2020Publication date: May 19, 2022Applicants: University of Tsukuba, SOINN Inc., Life Science Institute, Inc.Inventors: Yasuhiro FUJISAWA, Kodai IWASHITA, Mitsuyoshi ISHIDA
-
Patent number: 11335083Abstract: Provided are an object identification device and an object identification method in which objects can be easily identified. The object identification device is provided with a pixel group extraction unit which scans, in units of the image area, an X-ray transferred image obtained from an imaging unit which performs X-ray imaging to an item to be inspected that is supplied, and extracts a plurality of pixel groups including characteristics of a shape of at least a part of the item to be inspected, and a determination unit which determines, with regard to the plurality of pixel groups extracted by the pixel group extraction unit, whether the item to be inspected corresponds to the object by executing all of the series of mappings related to an angle of an n direction by using each of the weight parameters based on the data group read from the memory unit.Type: GrantFiled: January 11, 2019Date of Patent: May 17, 2022Assignees: CYBERDYNE INC., University of TsukubaInventor: Yoshiyuki Sankai
-
Patent number: 11313342Abstract: A wave-activated power generation device is disclosed. The device includes a float configured to be capable of floating in the sea; a rotor configured to generate a rotational inertial mass effect; a power generator configured to generate power based on rotation of the rotor; a first elastic body; and a drive part configured to connect the rotor with the float via the first elastic body so as to rotate the rotor along with movement of the float.Type: GrantFiled: August 21, 2018Date of Patent: April 26, 2022Assignee: University of TsukubaInventors: Takehiko Asai, Ruriko Haraguchi, Yoshikazu Araki
-
Patent number: 11300807Abstract: An image display device acquires positional information including a distance between at least one eye of an observer and an image display surface, and corrects, based on the acquired positional information, a relative positional relationship between slit areas and an image displayed on the image display surface, by using a width smaller than the width of one subpixel as a minimum correction unit.Type: GrantFiled: December 5, 2018Date of Patent: April 12, 2022Assignee: University of TsukubaInventors: Hideki Kakeya, Ayuki Hayashishita
-
Publication number: 20220071209Abstract: Provided is a plant pathogen control agent that is used to control plant pathogens on plants and is a novel method for using cellulose nanofibers. The plant pathogen control agent is a plant pathogen control agent containing plant-derived cellulose nanofibers as active ingredient, in which a surface of a nanofiber-coated layer to be formed by sparging or spraying the plant pathogen control agent onto the foliage or the stems of the plants and then by drying the plant pathogen control agent has hydrophilicity. Examples of the cellulose nanofibers include a plant-derived nanofiber material selected from the group consisting of gramineous plants, broadleaf trees, and needleleaf trees. Examples of the plants to be an application target include cabbage plants, soybean plants, tomato plants, tobacco plants, or coffee tree seedlings. In addition, examples of the plant pathogens to be a control target include causative bacterium, rust fungi, or pathogenic fungi.Type: ApplicationFiled: September 20, 2019Publication date: March 10, 2022Applicants: Marubeni Corporation, University of Tsukuba, Chuetsu Pulp and Paper Co., Ltd.Inventors: Yasuhiro ISHIGA, Hiroyuki TANAKA
-
Patent number: 11181487Abstract: A phase imaging method and apparatus are provided, the phase imaging method including causing a quantum beam from a radiation source to be incident on a detector through a test object and at least one phase grating and obtaining a phase image of the test object, based on intensity distribution of a beam in a pixel constituting the detector. The intensity distribution of the beam at least includes information of absorption (a0), visibility (V), and phase (?). At least three adjacent pixels are assumed to have a substantially identical value for each of the absorption (a0), the visibility (V), and the phase (?) through variable approximation of an image. The absorption, the visibility, and the phase are obtained, based on at least one measurement image.Type: GrantFiled: June 12, 2019Date of Patent: November 23, 2021Assignee: University of TsukubaInventors: Hiroyuki Kudo, Songzhe Lian
-
Patent number: 11136539Abstract: Proposed are a functional improvement evaluation apparatus and a nerve cell culture apparatus of model animals capable of performing feedback control, even to mammalian model animals, based on biosignals in the same manner has humans based on a relatively simple configuration.Type: GrantFiled: April 26, 2016Date of Patent: October 5, 2021Assignees: CYBERDYNE Inc., University of TsukubaInventor: Yoshiyuki Sankai
-
Patent number: 11059888Abstract: A regulatory T cell activator including a substance that inhibits the binding between DNAX accessory molecule-1 (DNAM-1) and CD155.Type: GrantFiled: April 19, 2017Date of Patent: July 13, 2021Assignee: University of TsukubaInventors: Akira Shibuya, Kazuko Shibuya, Fumie Abe, Rei Hirochika, Genki Okumura
-
Patent number: 11002678Abstract: A data creation method includes: an autofluorescence data generation step of placing a focus of light having a predetermined wavelength at one set of coordinates on a predetermined focal plane, irradiating a sample positioned at the set of coordinates with excitation light containing the light to obtain autofluorescence emitted from the sample, and generating autofluorescence data including intensity data and/or spectrum data of the autofluorescence; a reflected light data generation step of irradiating the set of coordinates on the predetermined focal plane with illumination light to obtain reflected light scattered by the sample, and generating intensity data of the reflected light; and a correspondence data creation step of creating correspondence data associating the autofluorescence data and the reflected light data on the set of coordinates on the predetermined focal plane.Type: GrantFiled: December 22, 2017Date of Patent: May 11, 2021Assignee: University of TsukubaInventors: Nobuhiko Nomura, Yutaka Yawata, Tatsunori Kiyokawa
-
Publication number: 20210108218Abstract: An expression system is provided, including a first nucleic acid fragment containing a long intergenic region (LIR) derived from geminivirus, a small intergenic region (SIR) derived from geminivirus, and an expression cassette of a target protein linked between the LIR and the SIR and a second nucleic acid fragment containing an expression cassette of a Rep/RepA protein derived from geminivirus, in which the expression cassette of the target protein includes a promoter, a nucleic acid fragment encoding the target protein, and two or more linked terminators in this order.Type: ApplicationFiled: March 6, 2018Publication date: April 15, 2021Applicant: University of TsukubaInventors: Kenji MIURA, Hiroshi EZURA, Ken HOSHIKAWA