Abstract: In order to develop tools and methods useful in a variety of applications, including the research and development of medical treatments which involve the modification of collagen protein and use of the same, the present invention provides a modified collagen protein expressed in a transformed cell and capable of forming collagen fibers outside of the cell, wherein the transformation is performed by introducing, into the cell, polynucleotides coding the modified collagen protein.

Abstract: A carbon nanostructure producing method includes a growth step in which a plurality of catalyst particles in close contact with each other are separated in a flow of a carbon-containing gas so as to grow carbon nanotubes between the plurality of catalyst particles, and an elongation step in which the carbon nanotube is elongated by a wind pressure of the carbon-containing gas with at least one of the catalyst particles being retained.

Abstract: Problem to be Solved A traverse that is percutaneously provided and a surgical instrument for percutaneously providing the transverse are provided. Solution A rod 10 is placed in each of two rod openings 113, 123 and a transverse bar 130 is inserted in two bar holes 111, 121. Set screws 140, 150 are screwed in screw holes 114, 124. The set screws 140, 150 press the transverse bar 130, thereby restraining the transverse bar 130 in the longitudinal direction. Since portions of the bar holes 111, 121 adjoin the rod openings 113, 123, the pressed transverse bar 130 contacts the rods 10 and pushes the rods 10 against the rod openings 113, 123. A protrusion 127 engages with the rods 10 to restrain hooks 110, 120 in the longitudinal direction and circumferential direction of the rods 10.

Abstract: A motion assisting apparatus includes a multijoint structure having links in series rotatably connected in a relative manner, the links being integrally deformed in a bendable manner, a linear member inserted through each of the links, wherein one end is fixed to the link in front and another end is elongated via the link in rear, a sliding/holding part which fixes an elongated portion of the linear member, and slidably guides the rear link in a connecting direction between each of the links, a drive unit which drives the rear link to slide toward the sliding/holding part and causes the multijoint structure, through which the linear member has been inserted, to engage in an extending or flexing motion, and a control unit which drive-controls the drive unit so that a sliding direction, a sliding speed and a sliding position of the rear link will become an intended state.

Abstract: The present invention aims to provide a novel low-molecular-weight compound showing an orexin receptor agonist activity and expected to be useful as a prophylactic or therapeutic agent for narcolepsy and the like. The present invention provides a compound represented by the formula (I): wherein each symbol is as described in the description, or a pharmaceutically acceptable acid addition salt thereof, which has an orexin receptor agonist activity, and an orexin receptor agonist containing the compound or a pharmaceutically acceptable acid addition salt thereof.

Abstract: A carbon nanotube composite assembled wire is a carbon nanotube composite assembled wire including a plurality of carbon nanotube composites, each of the plurality of carbon nanotube composites including one carbon nanotube and an amorphous carbon-containing layer that coats the carbon nanotube, the carbon nanotube having a D/G ratio of 0.1 or less, the D/G ratio being a ratio of a peak intensity of a D band to a peak intensity of a G band in Raman spectroscopic analysis with a wavelength of 532 nm, each of the plurality of carbon nanotube composites being fibrous and having a diameter of 0.1 ?m or more and 50 ?m or less, the plurality of carbon nanotube composites being oriented in a longitudinal direction of the carbon nanotube composite assembled wire.

Abstract: A paramylon-based resin excellent in mechanical characteristics and thermoplasticity is provided. The present embodiment provides a paramylon-based resin in which hydrogen atoms of hydroxy groups of paramylon are substituted by linear saturated aliphatic acyl group having 14 or more carbon atoms as a long chain component and/or acyl group having 2 or 3 carbon atoms (acetyl group or/and propionyl group) as a short chain component, wherein the paramylon has a weight average molecular weight in the range of more than 140000 to 220000 and a molecular weight distribution (weight average molecular weight/number average molecular weight) of 6.5 or less, a protein content of the paramylon is 0.22% by mass to 5.0% by mass, and a degree of substitution (DSLo) by the long chain component and a degree of substitution (DSSh) by the short chain component satisfy the following expressions (S1), (L1) and (T1); 1.7?DSSh?2.8 (S1), 0?DSLo?0.4 (L1), 2.1?DSLo+DSSh?2.8 (T1).

Abstract: A model learning unit determines a model parameter for calculating an estimated value for each of a plurality of training sets, each including a measurement signal and at least one type of predetermined characteristic value indicating characteristics of the measurement signal as a target value, to minimize a difference between the estimated value calculated for the measurement signal using a predetermined mathematical model and the target value is minimized, determines characteristic value sets, each being a set of a plurality of types of characteristic values indicating characteristics of the measurement signal including the target value, with which, for each target value, the target value is common to a plurality of characteristic value sets, and generates, for each of the characteristic value sets, each of the plurality of training sets including the target value and a measurement signal having characteristics indicated by the plurality of types of characteristic values.

Abstract: A gait disorder support apparatus and gait disorder support method capable of detecting an onset sign of a gait disorder associated with motor symptoms in advance and performing motion assist are proposed. The onset sign of the gait disorder associated with the motor symptoms of a wearer is detected based on the correlation between a gait cycle and a reduction ratio of the gait cycle as compared to immediately preceding gait; and when the onset sign of the gait disorder is detected, a drive unit is controlled so that the drive unit applies assist power to a knee joint of the wearer; and on the other hand, when the onset sign of the gait disorder is not detected, the drive unit is controlled so that driving torque by the drive unit does not hinder the wearer's gait motion.

Abstract: The invention provides an HIF-1 activator for treatment, prevention, alleviation, improvement or recovery from diseases or symptoms associated with reduced HIF-1 activity, as well as a pharmaceutical composition, cosmetic and food composition comprising the activator. Provided is an HIF-1 activator comprising olive leaf extract. Also provided is an HIF-1 activator which is for maintaining the undifferentiated state of stem cells via HIF-1 activation and/or improving dysdifferentiation of stem cells.

Abstract: A trained model generation program causes a computer to implement a learning execution function of inputting first input image data representing a first input image generated by a first reconstruction method using compressed sensing and second input image data representing a second input image generated by a second reconstruction method different from the first reconstruction method to a machine learning device to execute machine learning, the second reconstruction method being an analytical reconstruction method, and causing the machine learning device to generate a trained model, and a trained model acquisition function of acquiring trained model data indicating the trained model. Then, input image data representing an input image is input to the trained model to generate a reconstructed image with improved image quality.

Abstract: A diagnostic imaging support device includes: a learning unit that calculates a feature quantity about each of infectiousness condition and non-infectiousness condition for determining a condition in a determination image of an anterior eye through machine learning on the basis of a learning image of an anterior eye and information about a condition in the learning image.

Abstract: A biopotential can be measured with high accuracy without the electrodes coming into direct contact with the skin and without being affected by any motion artifact. The present invention comprises a first lead which detects a biopotential containing noise components, a second lead which is electrically isolated from the first lead and detects noise components, and a differential amplifier circuit which is input with a first signal output from the first lead and a second signal output from the second lead, and which amplifies and outputs a difference between the first signal and the second signal, wherein a value of an input impedance on the second signal side of the differential amplifier circuit is set so that the noise components detected from the second lead will have a frequency that is higher than a frequency spectrum of the biopotential.

Abstract: A musicality information provision method includes acquiring first performance data from a performance of a given composition, calculating, with respect to a combination of a plurality of parameters indicating musicality, which are included in the first performance data, respective distances between the first performance data and a plurality of sets of second performance data that are acquired from performances of the given composition and that are compared with the first performance data, and outputting determination information for determining the musicality of the first performance data, the determination information including information indicating the distances.

Abstract: A hydrogen generator includes a reaction vessel, a water supply, a temperature adjustor, and a controller. The reaction vessel houses a hydrogen generating material having hydrogen generating ability. The hydrogen generating material includes a two-dimensional hydrogen boride sheet having a two-dimensional network and containing multiple negatively charged boron atoms. The controller is configured to execute a hydrogen generating mode to generate hydrogen from the hydrogen generating material and a regenerating mode to recover the hydrogen generating ability of the hydrogen generating material. The controller controls the temperature adjustor to heat the hydrogen generating material at a first predetermined temperature during the hydrogen generating mode. The controller controls the temperature adjustor to adjust the temperature of the hydrogen generating material to a second predetermined temperature and controls the water supply to supply water during the regenerating mode.

Abstract: There is provided a mutant KLF protein that can induce reprogramming of a somatic cell at a higher efficiency than a KLF protein having a natural amino acid sequence. There is also provided a method for efficiently producing an iPS cell by using the mutant KLF protein. There is provided a mutant KLF protein having an amino acid substitution, or a peptide fragment thereof containing the amino acid substitution.

Abstract: The present invention provides a hydrogen storage and release material including a two-dimensional hydrogen boride-containing sheet including a two-dimensional network containing n(HxBy) (n?4, 0.001?x/y?0.999) having a molar ratio of boron to hydrogen from 1:0.999 to 1:0.001, the molar ratio being determined by thermal desorption spectroscopy, and mass measurement before and after a temperature rise, wherein the hydrogen storage and release material has: peaks derived from B1s of boron at 187.5±1.0 eV and 191.2±1.0 eV to 193±1.0 eV in X-ray photoelectron spectroscopy, and a peak derived from a B—H stretching vibration at from 2400 cm?1 to 2600 cm?1 and also a peak derived from a B—H—B stretching vibration at from 1200 cm?1 to 1800 cm?1 in infrared spectroscopy.

Abstract: A carbon nanotube composite is a carbon nanotube composite including one carbon nanotube and an amorphous carbon-containing layer that coats the carbon nanotube, the carbon nanotube having a D/G ratio of 0.1 or less, the D/G ratio being a ratio of a peak intensity of a D band to a peak intensity of a G band in Raman spectroscopic analysis with a wavelength of 532 nm, the carbon nanotube composite being fibrous and having a diameter of 0.1 ?m or more and 50 ?m or less.

Abstract: A carbon nanotube-resin composite includes: a carbon nanotube assembled wire including a plurality of carbon nanotubes; and a resin, wherein in the carbon nanotube assembled wire, the carbon nanotubes are oriented at a degree of orientation of 0.9 or more and 1 or less.

Abstract: As a sintered body for a radiation shielding material, which can effectively shield mainly low-energy-level neutrons, that is, thermal neutrons and lower, slow neutrons, and has excellent physical properties such as bending strength and Vickers hardness, leading to high machining strength, a sintered body for a radiation shielding material comprising LiF ranging between 99 wt. % to 5 wt. %, and one or more fluorides selected from among MgF2, CaF2, AlF3, KF, NaF, and/or YF3 ranging between 1 wt. % to 95 wt. %, having physical properties of a relative density of 92% or more, a bending strength of 50 MPa or more, and a Vickers hardness of 100 or more, is provided.